#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0049"(filter binding) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8375586|mint:MINT-1773416 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1773422(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1773433(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:7D47E923CA5C8477|rigid:264Za2O351duNPzrrfYQEFrQlRE false binding-associated region:531-551(MINT-1773429)|mutation disrupting interaction:551-551(MINT-1773431)|biotin tag:n-n(MINT-1773423) glutathione s tranferase tag:?-?(MINT-1773434)|binding-associated region:1-118(MINT-1773440) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0049"(filter binding) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8375645|mint:MINT-1793958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1793960(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1793971(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:4C1B499DAFF3E820|rigid:264Za2O351duNPzrrfYQEFrQlRE false binding-associated region:531-551(MINT-1793963)|biotin tag:n-n(MINT-1793969)|mutation disrupting interaction:551-551(MINT-1793961) glutathione s tranferase tag:?-?(MINT-1793979)|binding-associated region:149-257(MINT-1793972) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8375681|mint:MINT-1773472 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1773484(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1773478(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:mint taxid:9986(rabbit-kidney glomer)|taxid:9986(Oryctolagus cuniculus) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:3BB557834DADEECC|rigid:264Za2O351duNPzrrfYQEFrQlRE false - - 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0084"(phage display) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8375718|mint:MINT-1773374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1773388(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1773405(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:481FC2DDCB937099|rigid:264Za2O351duNPzrrfYQEFrQlRE false binding-associated region:531-551(MINT-1773395)|biotin tag:n-n(MINT-1773389) binding-associated region:151-228(MINT-1773411) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8375768|mint:MINT-1773521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1773523(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1773529(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:24BE90E4F423A025|rigid:264Za2O351duNPzrrfYQEFrQlRE false - binding-associated region:1-118(MINT-1773536)|glutathione s tranferase tag:?-?(MINT-1773530) 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8375747|mint:MINT-1773445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1773451(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1773462(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:A5A54077FEFAB272|rigid:264Za2O351duNPzrrfYQEFrQlRE false binding-associated region:531-551(MINT-1773458)|biotin tag:n-n(MINT-1773452)|mutation disrupting interaction:551-551(MINT-1773460) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q28645 uniprotkb:Q8SQG9 intact:EBI-8375591|intact:MINT-1773380 intact:EBI-1174758 psi-mi:podxl_rabit(display_long)|uniprotkb:PODXL(gene name)|psi-mi:PODXL(display_short)|uniprotkb:PCLP1(gene name synonym)|uniprotkb:Podocalyxin-like protein 1(gene name synonym) psi-mi:nhrf2_rabit(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:PDZ domain-containing protein NHERF-2(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Li et al. (2002) pubmed:11997330|mint:MINT-5215361 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8375787|mint:MINT-1793937 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013836(CD34/Podocalyxin)|refseq:NP_001076235.1|interpro:IPR017403(Podocalyxin-like protein 1)|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0036057"(slit diaphragm)|go:"GO:0045121"(membrane raft)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072175"(epithelial tube formation)|mint:MINT-1793949(identity) interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:NP_001075576.1|interpro:IPR031197|go:"GO:0005634"(nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR036034|mint:MINT-1793939(identity) - comment:mint|function:Functions as an antiadhesin that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:domino|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/07 2014/10/16 rogid:Ghevdo8u2W/iFeKC6pQFUjhFHq09986 rogid:6tAxAfhRA5wjSikCvOHoM5Qm1Ik9986 intact-crc:4F050D6D3078E90D|rigid:264Za2O351duNPzrrfYQEFrQlRE false - binding-associated region:149-257(MINT-1793940)|glutathione s tranferase tag:?-?(MINT-1793947) 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification)