#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q09591	uniprotkb:Q20060	intact:EBI-1152136|ensemblmetazoa:M106.1.1	intact:EBI-1152127|ensemblmetazoa:F35G12.8.1|ensemblmetazoa:F35G12.8.2	psi-mi:mix1_caeel(display_long)|uniprotkb:Structural maintenance of chromosomes protein 2(gene name synonym)|uniprotkb:Lethal protein 29(gene name synonym)|uniprotkb:mix-1(gene name)|psi-mi:mix-1(display_short)|uniprotkb:let-29(gene name synonym)|uniprotkb:smc-2(gene name synonym)|uniprotkb:M106.1(orf name)	psi-mi:smc4_caeel(display_long)|uniprotkb:smc-4(gene name)|psi-mi:smc-4(display_short)|uniprotkb:F35G12.8(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hagstrom et al. (2002)	pubmed:11914278|imex:IM-27306	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1152148|imex:IM-27306-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036277|refseq:NP_496331.1|wormbase:M106.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|interpro:IPR024704|reactome:R-CEL-2299718|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:0007076"(mitotic chromosome condensation)|ensemblmetazoa:M106.1.1(transcript)|ensemblmetazoa:WBGene00003367(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|interpro:IPR027120|reactome:R-CEL-2514853	interpro:IPR036277|refseq:NP_497935.1|wormbase:F35G12.8|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|ensemblmetazoa:F35G12.8.1(transcript)|ensemblmetazoa:F35G12.8.2(transcript)|ensemblmetazoa:WBGene00004874(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-2299718|reactome:R-CEL-2514853|interpro:IPR041738	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2006/11/01	2014/10/16	rogid:8+HyNebI+yO6q+Ue+R8W5exBZiI6239	rogid:B5+QPuo8PZea/B+rguC7zhpop1Q6239	intact-crc:74BBF99633FB6072|rigid:6c85gXJaXUeRc1XSbGLcxtLZ3CQ	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q09591	uniprotkb:P48996	intact:EBI-1152136|ensemblmetazoa:M106.1.1	intact:EBI-1152153|ensemblmetazoa:R13G10.1.1	psi-mi:mix1_caeel(display_long)|uniprotkb:Structural maintenance of chromosomes protein 2(gene name synonym)|uniprotkb:Lethal protein 29(gene name synonym)|uniprotkb:mix-1(gene name)|psi-mi:mix-1(display_short)|uniprotkb:let-29(gene name synonym)|uniprotkb:smc-2(gene name synonym)|uniprotkb:M106.1(orf name)	psi-mi:dpy27_caeel(display_long)|uniprotkb:Protein dumpy-27(gene name synonym)|uniprotkb:dpy-27(gene name)|psi-mi:dpy-27(display_short)|uniprotkb:R13G10.1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hagstrom et al. (2002)	pubmed:11914278|imex:IM-27306	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1152165|imex:IM-27306-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036277|refseq:NP_496331.1|wormbase:M106.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|interpro:IPR024704|reactome:R-CEL-2299718|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:0007076"(mitotic chromosome condensation)|ensemblmetazoa:M106.1.1(transcript)|ensemblmetazoa:WBGene00003367(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|interpro:IPR027120|reactome:R-CEL-2514853	interpro:IPR036277|refseq:NP_497771.1|wormbase:R13G10.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|ensemblmetazoa:R13G10.1.1(transcript)|ensemblmetazoa:WBGene00001086(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046536"(dosage compensation complex)	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2006/11/01	2014/10/16	rogid:8+HyNebI+yO6q+Ue+R8W5exBZiI6239	rogid:5aBfvWjTWYJ/kl3LutsfeBti2/M6239	intact-crc:0364295CB65B04DA|rigid:T0VzLUf++iWvt+tgrzC+lNf5J/A	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q09591	uniprotkb:Q20060	intact:EBI-1152136|ensemblmetazoa:M106.1.1	intact:EBI-1152127|ensemblmetazoa:F35G12.8.1|ensemblmetazoa:F35G12.8.2	psi-mi:mix1_caeel(display_long)|uniprotkb:Structural maintenance of chromosomes protein 2(gene name synonym)|uniprotkb:Lethal protein 29(gene name synonym)|uniprotkb:mix-1(gene name)|psi-mi:mix-1(display_short)|uniprotkb:let-29(gene name synonym)|uniprotkb:smc-2(gene name synonym)|uniprotkb:M106.1(orf name)	psi-mi:smc4_caeel(display_long)|uniprotkb:smc-4(gene name)|psi-mi:smc-4(display_short)|uniprotkb:F35G12.8(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hagstrom et al. (2002)	pubmed:11914278|imex:IM-27306	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1152172|imex:IM-27306-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036277|refseq:NP_496331.1|wormbase:M106.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|interpro:IPR024704|reactome:R-CEL-2299718|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:0007076"(mitotic chromosome condensation)|ensemblmetazoa:M106.1.1(transcript)|ensemblmetazoa:WBGene00003367(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|interpro:IPR027120|reactome:R-CEL-2514853	interpro:IPR036277|refseq:NP_497935.1|wormbase:F35G12.8|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|ensemblmetazoa:F35G12.8.1(transcript)|ensemblmetazoa:F35G12.8.2(transcript)|ensemblmetazoa:WBGene00004874(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-2299718|reactome:R-CEL-2514853|interpro:IPR041738	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2006/11/01	2017/10/10	rogid:8+HyNebI+yO6q+Ue+R8W5exBZiI6239	rogid:B5+QPuo8PZea/B+rguC7zhpop1Q6239	intact-crc:BCF5E6C8B1410DC9|rigid:GE8pFnJYX7sClU48pr/2Ray3CDM	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q09591	uniprotkb:P48996	intact:EBI-1152136|ensemblmetazoa:M106.1.1	intact:EBI-1152153|ensemblmetazoa:R13G10.1.1	psi-mi:mix1_caeel(display_long)|uniprotkb:Structural maintenance of chromosomes protein 2(gene name synonym)|uniprotkb:Lethal protein 29(gene name synonym)|uniprotkb:mix-1(gene name)|psi-mi:mix-1(display_short)|uniprotkb:let-29(gene name synonym)|uniprotkb:smc-2(gene name synonym)|uniprotkb:M106.1(orf name)	psi-mi:dpy27_caeel(display_long)|uniprotkb:Protein dumpy-27(gene name synonym)|uniprotkb:dpy-27(gene name)|psi-mi:dpy-27(display_short)|uniprotkb:R13G10.1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hagstrom et al. (2002)	pubmed:11914278|imex:IM-27306	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1152172|imex:IM-27306-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036277|refseq:NP_496331.1|wormbase:M106.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|interpro:IPR024704|reactome:R-CEL-2299718|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:0007076"(mitotic chromosome condensation)|ensemblmetazoa:M106.1.1(transcript)|ensemblmetazoa:WBGene00003367(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|interpro:IPR027120|reactome:R-CEL-2514853	interpro:IPR036277|refseq:NP_497771.1|wormbase:R13G10.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|ensemblmetazoa:R13G10.1.1(transcript)|ensemblmetazoa:WBGene00001086(gene)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000805"(X chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046536"(dosage compensation complex)	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2006/11/01	2017/10/10	rogid:8+HyNebI+yO6q+Ue+R8W5exBZiI6239	rogid:5aBfvWjTWYJ/kl3LutsfeBti2/M6239	intact-crc:BCF5E6C8B1410DC9|rigid:GE8pFnJYX7sClU48pr/2Ray3CDM	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q20060	uniprotkb:Q09591	intact:EBI-1152127|ensemblmetazoa:F35G12.8.1|ensemblmetazoa:F35G12.8.2	intact:EBI-1152136|ensemblmetazoa:M106.1.1	psi-mi:smc4_caeel(display_long)|uniprotkb:smc-4(gene name)|psi-mi:smc-4(display_short)|uniprotkb:F35G12.8(orf name)	psi-mi:mix1_caeel(display_long)|uniprotkb:Structural maintenance of chromosomes protein 2(gene name synonym)|uniprotkb:Lethal protein 29(gene name synonym)|uniprotkb:mix-1(gene name)|psi-mi:mix-1(display_short)|uniprotkb:let-29(gene name synonym)|uniprotkb:smc-2(gene name synonym)|uniprotkb:M106.1(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Hagstrom et al. (2002)	pubmed:11914278|imex:IM-27306	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1152189|imex:IM-27306-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR036277|refseq:NP_497935.1|wormbase:F35G12.8|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|ensemblmetazoa:F35G12.8.1(transcript)|ensemblmetazoa:F35G12.8.2(transcript)|ensemblmetazoa:WBGene00004874(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|reactome:R-CEL-2299718|reactome:R-CEL-2514853|interpro:IPR041738	interpro:IPR036277|refseq:NP_496331.1|wormbase:M106.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR027417|interpro:IPR024704|reactome:R-CEL-2299718|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0042464"(dosage compensation by hypoactivation of X chromosome)|go:"GO:0046536"(dosage compensation complex)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0110039"(positive regulation of nematode male tail tip morphogenesis)|go:"GO:0007076"(mitotic chromosome condensation)|ensemblmetazoa:M106.1.1(transcript)|ensemblmetazoa:WBGene00003367(gene)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005524"(ATP binding)|interpro:IPR027120|reactome:R-CEL-2514853	-	-	-	figure legend:Fig. 2L-2Q|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2006/11/01	2014/10/16	rogid:B5+QPuo8PZea/B+rguC7zhpop1Q6239	rogid:8+HyNebI+yO6q+Ue+R8W5exBZiI6239	intact-crc:02254AF53B482B11|rigid:6c85gXJaXUeRc1XSbGLcxtLZ3CQ	false	-	-	-	-	psi-mi:"MI:0709"(polyclonal antibody immunostaining)	psi-mi:"MI:0709"(polyclonal antibody immunostaining)