#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01903	uniprotkb:P01911	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287	intact:EBI-1033104|uniprotkb:O19717|uniprotkb:O19739|uniprotkb:P13759|uniprotkb:Q29875|uniprotkb:Q30145|uniprotkb:Q9GIX9|uniprotkb:Q9GIY4|uniprotkb:Q9MY13|uniprotkb:Q9XRY5|uniprotkb:Q0PQ39|uniprotkb:Q14280|uniprotkb:Q14QT2|uniprotkb:Q155F7|uniprotkb:Q19AF2|uniprotkb:Q19K86|uniprotkb:Q1AP33|uniprotkb:Q1G0Z9|uniprotkb:Q1JRP3|uniprotkb:Q1KLJ6|uniprotkb:Q27PR6|uniprotkb:Q27PR7|uniprotkb:Q29673|uniprotkb:Q29720|uniprotkb:Q29722|uniprotkb:Q29734|uniprotkb:Q29770|uniprotkb:Q29771|uniprotkb:A0MWF2|uniprotkb:A0N0W1|uniprotkb:A2ICT1|uniprotkb:A2TGX3|uniprotkb:A4F5N0|uniprotkb:A4ZXA5|uniprotkb:A4ZXA6|uniprotkb:A4ZY86|uniprotkb:A5H000|ensembl:ENSP00000353099|uniprotkb:A5HKN8|uniprotkb:A7DZP9|uniprotkb:A7LA26|uniprotkb:A7UHG2|uniprotkb:A7X5B1|uniprotkb:A7X5B7|uniprotkb:A7X5E0|uniprotkb:A7X5E6|uniprotkb:A7X5H8|uniprotkb:A7X5J4|uniprotkb:A7X5K7|uniprotkb:A8K098|uniprotkb:A8YQE9|uniprotkb:A9JPG0|uniprotkb:B0BK85|uniprotkb:B1GWE7|uniprotkb:B2CR03|uniprotkb:B0LUZ6|uniprotkb:B0UYW1|uniprotkb:Q768U2|uniprotkb:Q29772|uniprotkb:Q29790|uniprotkb:Q29792|uniprotkb:Q29800|uniprotkb:Q29806|uniprotkb:Q29833|uniprotkb:Q29874|uniprotkb:Q29886|uniprotkb:Q29968|uniprotkb:Q29974|uniprotkb:Q29975|uniprotkb:Q2A120|uniprotkb:Q2HZE5|uniprotkb:Q2L9H4|uniprotkb:Q2LE76|uniprotkb:Q2MF40|uniprotkb:Q2MJA6|uniprotkb:Q2MZ92|uniprotkb:Q2VQU1|uniprotkb:Q2YHQ2|uniprotkb:Q30006|uniprotkb:Q30108|uniprotkb:Q30112|uniprotkb:Q30115|uniprotkb:Q30116|uniprotkb:Q30117|uniprotkb:Q30120|uniprotkb:Q30134|uniprotkb:Q30142|uniprotkb:Q30149|uniprotkb:Q30159|uniprotkb:Q30166|uniprotkb:Q30167|uniprotkb:Q30200|uniprotkb:Q307W5|uniprotkb:Q31636|uniprotkb:Q32MY7|uniprotkb:Q3HUP9|uniprotkb:Q3KTM1|uniprotkb:Q3LA84|uniprotkb:Q3LA87|uniprotkb:Q3LA88|uniprotkb:Q3LA89|uniprotkb:Q3LA90|uniprotkb:Q3LA91|uniprotkb:Q3LA92|uniprotkb:Q3LA93|uniprotkb:Q3LA94|uniprotkb:Q3LA95|uniprotkb:Q3LA96|uniprotkb:Q3LA97|uniprotkb:Q3LA98|uniprotkb:Q3LA99|uniprotkb:Q3LAA0|uniprotkb:Q3LAA1|uniprotkb:Q3LAA2|uniprotkb:Q3MQ60|uniprotkb:Q3T919|uniprotkb:Q4PRC3|uniprotkb:Q4PRC5|uniprotkb:Q4VZY7|uniprotkb:Q53IG1|uniprotkb:Q56FN9|uniprotkb:Q56FP1|uniprotkb:Q56FP2|uniprotkb:Q56FP3|uniprotkb:Q58F52|uniprotkb:Q5BM92|uniprotkb:Q5EER6|uniprotkb:Q5K3W2|uniprotkb:Q5NDB9|uniprotkb:Q5U9W6|uniprotkb:Q5UBA2|uniprotkb:Q5UT58|uniprotkb:Q5W3L4|uniprotkb:Q5Y7A7|uniprotkb:Q5Y7B0|uniprotkb:Q5Y7B9|uniprotkb:Q5Y7E9|uniprotkb:Q5Y7G0|uniprotkb:Q683P7|uniprotkb:Q6REE2|uniprotkb:Q6T865|uniprotkb:Q6U387|uniprotkb:Q701T1|uniprotkb:Q70GL2|uniprotkb:Q70Q85|uniprotkb:Q768U4|uniprotkb:Q7M2H4|uniprotkb:Q7YNY9|uniprotkb:Q7YP03|uniprotkb:Q7YP04|uniprotkb:Q7YQ26|uniprotkb:Q7YQA3|uniprotkb:Q7YQA5|uniprotkb:Q860D8|uniprotkb:Q860D9|uniprotkb:Q860E5|uniprotkb:Q860H8|uniprotkb:Q860S0|uniprotkb:Q860Z3|uniprotkb:Q861G6|uniprotkb:Q861H0|uniprotkb:Q861H4|uniprotkb:Q861H5|uniprotkb:Q861H7|uniprotkb:Q861H8|uniprotkb:Q8HWQ6|uniprotkb:Q8MH59|uniprotkb:Q8MH60|uniprotkb:Q8WLU3|uniprotkb:Q8WMA0|uniprotkb:Q95348|uniprotkb:Q95383|uniprotkb:Q95389|uniprotkb:Q95461|uniprotkb:Q95HK1|uniprotkb:Q95HL0|uniprotkb:Q95HL1|uniprotkb:Q95IE3|uniprotkb:Q95IG2|uniprotkb:Q95IT6|uniprotkb:Q96HZ9|uniprotkb:Q9BCL7|uniprotkb:Q9BCP0|uniprotkb:Q9BCP1|uniprotkb:Q9BCP2|uniprotkb:Q9BCP5|uniprotkb:Q9BD21|uniprotkb:Q9BD33|uniprotkb:Q9BD40|uniprotkb:Q9GIK5|uniprotkb:Q9GIL5|uniprotkb:Q9GIL6|uniprotkb:Q9GIP3|uniprotkb:Q9GIX8|uniprotkb:Q9GIY0|uniprotkb:Q9GIY1|uniprotkb:Q9GIY2|uniprotkb:B2LVF9|uniprotkb:B2NJ29|uniprotkb:B2ZCY1|uniprotkb:B3VTP8|uniprotkb:B3VTQ3|uniprotkb:B5A8Y2|uniprotkb:B5A8Y3|uniprotkb:C0LAB5|uniprotkb:B5B8U0|uniprotkb:B5B9V5|uniprotkb:B5B9V6|uniprotkb:B5LZ25|uniprotkb:B5QSK8|uniprotkb:B6VCX2|uniprotkb:B6VEL9|uniprotkb:B7UDB2|uniprotkb:B9VRA4|uniprotkb:B9X248|uniprotkb:Q0PGR5|uniprotkb:O02876|uniprotkb:O02930|uniprotkb:O19585|uniprotkb:O19718|uniprotkb:O19788|uniprotkb:O46699|uniprotkb:O46793|uniprotkb:O46872|uniprotkb:O62869|uniprotkb:O62889|uniprotkb:O77969|uniprotkb:O78047|uniprotkb:O78210|uniprotkb:O98212|uniprotkb:P01912|uniprotkb:P01914|uniprotkb:P04229|uniprotkb:P13758|uniprotkb:P13760|uniprotkb:P13761|uniprotkb:P20039|uniprotkb:P79545|uniprotkb:Q06662|intact:EBI-3866098|intact:EBI-13953066|uniprotkb:Q9GIY3|uniprotkb:Q9GJ25|uniprotkb:Q9GJ56|uniprotkb:Q9GJ57|uniprotkb:Q9GJ58|uniprotkb:Q9GJ60|uniprotkb:Q9GJF8|uniprotkb:Q9GJF9|uniprotkb:Q9GJG0|uniprotkb:Q9MXZ0|uniprotkb:Q9MXZ5|uniprotkb:Q9MY45|uniprotkb:Q9MY56|uniprotkb:Q9MYF5|uniprotkb:Q9TPB6|uniprotkb:Q9TPW1|uniprotkb:Q9TPW3|uniprotkb:Q9TPW9|uniprotkb:Q9TPX4|uniprotkb:Q9TQ37|uniprotkb:Q9TQ91|uniprotkb:Q9TQE0|uniprotkb:Q9UBY1|uniprotkb:Q9UIM9|uniprotkb:Q9UIN0|uniprotkb:Q9XRX1|uniprotkb:Q9XRY4|uniprotkb:Q9Y453|uniprotkb:Q9Y4H7|intact:EBI-13953170|intact:EBI-2877159	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:drb1_human(display_long)|uniprotkb:HLA-DRB1(gene name)|psi-mi:HLA-DRB1(display_short)|uniprotkb:Human leukocyte antigen DRB1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Hennecke et al. (2002)	pubmed:11877480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1033150|rcsb pdb:1J8H	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N	refseq:NP_002115.2|ensembl:ENSG00000196126(gene)|ensembl:ENST00000360004(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001772"(immunological synapse)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016045"(detection of bacterium)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032673"(regulation of interleukin-4 production)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051262"(protein tetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FYT|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:1R5I|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:1T5X|rcsb pdb:1YMM|rcsb pdb:2FSE|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:2SEB|rcsb pdb:2WBJ|rcsb pdb:2XN9|rcsb pdb:3L6F|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6HBY|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|refseq:XP_011546040.1|refseq:NP_001230894.1	-	-	-	assembly:pentameric, multimeric|3d-r-factors:working 78.900%, free 75.400%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2021/02/11	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:YdQX0KNIxO5tYjgm6hdRRZfNlk49606	intact-crc:F9FA9F165B801189|rigid:257IQ6GyDSMtf3Ny02FQT9gdfnM	false	sufficient binding region:26-206	sufficient binding region:30-221	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01903	uniprotkb:P03437	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287	intact:EBI-1033097|uniprotkb:A0PC85|uniprotkb:Q67132	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:hema_i68a0(display_long)|uniprotkb:HA(gene name)|psi-mi:HA(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Hennecke et al. (2002)	pubmed:11877480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:387139(i68a0)|taxid:387139("Influenza A virus (strain A/Aichi/2/1968 H3N2)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1033150|rcsb pdb:1J8H	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N	go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|interpro:IPR000149(Haemagglutinin, influenza A/B virus type, HA1 chain)|interpro:IPR001364(Haemagglutinin, influenza A/B virus type, HA1/HA2 chain)|interpro:IPR008980(Viral capsid/haemagglutinin protein)|interpro:IPR013828(Haemagglutinin, HA1 chain, alpha/beta region)|rcsb pdb:1EO8|rcsb pdb:1FYT|rcsb pdb:1HA0|rcsb pdb:1HGG|rcsb pdb:1HTM|rcsb pdb:1J8H|rcsb pdb:1KEN|rcsb pdb:1KG0|rcsb pdb:1PYW|rcsb pdb:1QFU|rcsb pdb:1QU1|rcsb pdb:2HMG|rcsb pdb:2VIR|rcsb pdb:2VIS|rcsb pdb:2VIT|rcsb pdb:2VIU|rcsb pdb:2YPG|rcsb pdb:3EYM|rcsb pdb:3HMG|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3VUN|rcsb pdb:4C56|rcsb pdb:4HMG|rcsb pdb:5HMG|rcsb pdb:6E56|rcsb pdb:6N5D|rcsb pdb:6N5E|rcsb pdb:6XPX|rcsb pdb:6Y5L|go:"GO:0020002"(host cell plasma membrane)|dip:DIP-45342N	-	-	-	assembly:pentameric, multimeric|3d-r-factors:working 78.900%, free 75.400%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2021/02/11	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:/L5FEF9locc5e/OC0yTdbuKaqFI387139	intact-crc:F9FA9F165B801189|rigid:257IQ6GyDSMtf3Ny02FQT9gdfnM	false	sufficient binding region:26-206	sufficient binding region:322-334	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01903	uniprotkb:P01848	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287	intact:EBI-1034847|uniprotkb:A0A087WWC6	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:trac_human(display_long)|uniprotkb:TRAC(gene name)|psi-mi:TRAC(display_short)|uniprotkb:TCRA(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Hennecke et al. (2002)	pubmed:11877480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1033150|rcsb pdb:1J8H	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N	rcsb pdb:4PRP|rcsb pdb:3D39|rcsb pdb:3QUX|rcsb pdb:4APQ|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:6DKP|rcsb pdb:5KS9|rcsb pdb:5KSA|rcsb pdb:5KSB|rcsb pdb:1FYT|rcsb pdb:3PWP|rcsb pdb:3QJF|rcsb pdb:3SJV|rcsb pdb:3T0E|rcsb pdb:3TN0|rcsb pdb:3TVM|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948|rcsb pdb:4ONH|rcsb pdb:4NHU|rcsb pdb:4Y2D|rcsb pdb:4Y4F|rcsb pdb:4Y4H|rcsb pdb:4Y4K|rcsb pdb:5BRZ|rcsb pdb:5BS0|interpro:IPR015370(Protein of unknown function DUF1968)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1J8H|rcsb pdb:1KGC|rcsb pdb:1MI5|rcsb pdb:1OGA|rcsb pdb:1QRN|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2AK4|rcsb pdb:2BNQ|rcsb pdb:2BNR|rcsb pdb:2BNU|rcsb pdb:2ESV|rcsb pdb:2EYR|rcsb pdb:2EYS|rcsb pdb:2EYT|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GJ6|rcsb pdb:2IAL|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2PYF|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLM|rcsb pdb:2VLR|rcsb pdb:2XN9|rcsb pdb:2XNA|rcsb pdb:3DX9|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:3GSN|rcsb pdb:3HG1|rcsb pdb:3KPR|rcsb pdb:3KPS|rcsb pdb:3KXF|rcsb pdb:3O6F|rcsb pdb:3O8X|rcsb pdb:3O9W|rcsb pdb:3QDG|rcsb pdb:3QDJ|rcsb pdb:3QDM|rcsb pdb:3QEQ|rcsb pdb:3QEU|rcsb pdb:4MVB|rcsb pdb:4MXQ|rcsb pdb:4N0C|rcsb pdb:4N5E|rcsb pdb:4Y16|rcsb pdb:5HHM|rcsb pdb:5HHO|rcsb pdb:5HYJ|rcsb pdb:4WW1|rcsb pdb:4WW2|rcsb pdb:4WWK|rcsb pdb:4ZDH|rcsb pdb:5C07|rcsb pdb:5C08|rcsb pdb:5C09|rcsb pdb:5C0A|rcsb pdb:5C0B|rcsb pdb:5C0C|rcsb pdb:5EU6|rcsb pdb:3SCM|rcsb pdb:3SDA|rcsb pdb:3SDC|rcsb pdb:3SDD|rcsb pdb:3SDX|rcsb pdb:3SKN|rcsb pdb:1AO7|rcsb pdb:1BD2|rcsb pdb:5FK9|rcsb pdb:5FKA|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0009617"(response to bacterium)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|rcsb pdb:4G8E|rcsb pdb:4G8F|rcsb pdb:4JRX|rcsb pdb:4JRY|reactome:R-HSA-202427|rcsb pdb:4P4K|rcsb pdb:4UDT|rcsb pdb:4UDU|rcsb pdb:4X6B|rcsb pdb:4X6C|rcsb pdb:4X6D|reactome:R-HSA-198933|reactome:R-HSA-202424|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFH|rcsb pdb:2CDF|rcsb pdb:2CDG|rcsb pdb:3QIB|rcsb pdb:3ARB|rcsb pdb:3ARD|rcsb pdb:3ARE|rcsb pdb:3ARF|rcsb pdb:3ARG|rcsb pdb:3O4L|rcsb pdb:4C56|rcsb pdb:1QSF|rcsb pdb:3HE7|rcsb pdb:4IRS|rcsb pdb:5JZI|interpro:IPR036179|rcsb pdb:5NQK|rcsb pdb:6JXR	-	-	-	assembly:pentameric, multimeric|3d-r-factors:working 78.900%, free 75.400%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2021/02/11	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:5bcFWiVM2BbHI9XW+lBqH50aj1g9606	intact-crc:F9FA9F165B801189|rigid:257IQ6GyDSMtf3Ny02FQT9gdfnM	false	sufficient binding region:26-206	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P01903	uniprotkb:P01850	intact:EBI-1030473|uniprotkb:Q30160|uniprotkb:Q6IAZ1|uniprotkb:Q861I2|uniprotkb:Q9TP70|uniprotkb:A2BET4|ensembl:ENSP00000372608|ensembl:ENSP00000372746|ensembl:ENSP00000378786|ensembl:ENSP00000402951|ensembl:ENSP00000404533|ensembl:ENSP00000405295|ensembl:ENSP00000410443|ensembl:ENSP00000479287	intact:EBI-1034839|uniprotkb:A0A5B8|uniprotkb:A6NH51|uniprotkb:A0A0J9YYE9	psi-mi:dra_human(display_long)|uniprotkb:HLA-DRA(gene name)|psi-mi:HLA-DRA(display_short)|uniprotkb:MHC class II antigen DRA(gene name synonym)|uniprotkb:HLA-DRA1(gene name synonym)	psi-mi:trbc1_human(display_long)|uniprotkb:TRBC1(gene name)|psi-mi:TRBC1(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Hennecke et al. (2002)	pubmed:11877480	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1033150|rcsb pdb:1J8H	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061984.2|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002469"(myeloid dendritic cell antigen processing and presentation)|go:"GO:0002491"(antigen processing and presentation of endogenous peptide antigen via MHC class II)|go:"GO:0002503"(peptide antigen assembly with MHC class II protein complex)|go:"GO:0002504"(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|ensembl:ENST00000416883(transcript)|go:"GO:0023026"(MHC class II protein complex binding)|ensembl:ENST00000442960(transcript)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032395"(MHC class II receptor activity)|go:"GO:0032588"(trans-Golgi network membrane)|ensembl:ENST00000613328(transcript)|go:"GO:0032831"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0045622"(regulation of T-helper cell differentiation)|go:"GO:0050890"(cognition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:2000516"(positive regulation of CD4-positive, alpha-beta T cell activation)|interpro:IPR001003(MHC class II, alpha chain, N-terminal)|go:"GO:0001772"(immunological synapse)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR036179|rcsb pdb:1A6A|rcsb pdb:1AQD|rcsb pdb:1BX2|rcsb pdb:1D5M|rcsb pdb:1D5X|rcsb pdb:1D5Z|rcsb pdb:1D6E|rcsb pdb:1DLH|rcsb pdb:1FV1|rcsb pdb:1FYT|rcsb pdb:1H15|rcsb pdb:1HQR|rcsb pdb:1HXY|rcsb pdb:1J8H|rcsb pdb:1JWM|rcsb pdb:1JWS|rcsb pdb:1JWU|rcsb pdb:1KG0|rcsb pdb:1KLG|rcsb pdb:2G9H|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2ICW|rcsb pdb:2IPK|rcsb pdb:2OJE|rcsb pdb:1KLU|rcsb pdb:2Q6W|rcsb pdb:2SEB|rcsb pdb:1LO5|rcsb pdb:1PYW|rcsb pdb:2WBJ|rcsb pdb:1R5I|rcsb pdb:2XN9|rcsb pdb:3C5J|rcsb pdb:3L6F|rcsb pdb:1SEB|rcsb pdb:1SJE|rcsb pdb:3O6F|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|rcsb pdb:3QXA|rcsb pdb:3QXD|rcsb pdb:3S4S|rcsb pdb:3S5L|rcsb pdb:3T0E|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4C56|rcsb pdb:4E41|rcsb pdb:4FQX|rcsb pdb:4GBX|rcsb pdb:4H1L|rcsb pdb:4H25|rcsb pdb:4H26|rcsb pdb:4I5B|rcsb pdb:4IS6|rcsb pdb:1SJH|rcsb pdb:1T5W|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD4|rcsb pdb:1T5X|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4OV5|rcsb pdb:1YMM|rcsb pdb:4X5W|rcsb pdb:4X5X|rcsb pdb:4Y19|rcsb pdb:4Y1A|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5V4M|rcsb pdb:5V4N|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6ATZ|rcsb pdb:1ZGL|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6BIN|rcsb pdb:6BIR|rcsb pdb:6BIV|rcsb pdb:6BIX|rcsb pdb:6BIY|rcsb pdb:6BIZ|rcsb pdb:2FSE|rcsb pdb:6CPL|rcsb pdb:6CPN|rcsb pdb:6CPO|rcsb pdb:6CQJ|rcsb pdb:6CQL|rcsb pdb:6CQN|rcsb pdb:6CQQ|rcsb pdb:6CQR|rcsb pdb:6NIX|rcsb pdb:6QZA|rcsb pdb:6QZC|rcsb pdb:6QZD|rcsb pdb:6R0E|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2132295|reactome:R-HSA-389948|reactome:R-HSA-877300|rcsb pdb:6V0Y|ensembl:ENSG00000204287(gene)|ensembl:ENSG00000206308(gene)|ensembl:ENSG00000226260(gene)|ensembl:ENSG00000227993(gene)|ensembl:ENSG00000228987(gene)|ensembl:ENSG00000230726(gene)|ensembl:ENSG00000234794(gene)|ensembl:ENSG00000277263(gene)|ensembl:ENST00000383127(transcript)|ensembl:ENST00000383259(transcript)|ensembl:ENST00000395388(transcript)|ensembl:ENST00000411524(transcript)|ensembl:ENST00000414698(transcript)|dip:DIP-6063N	rcsb pdb:4L9L|rcsb pdb:4LCC|rcsb pdb:4LCW|rcsb pdb:4MNQ|rcsb pdb:3D3V|rcsb pdb:4NQC|rcsb pdb:4NQD|rcsb pdb:4NQE|rcsb pdb:4OZF|rcsb pdb:4OZG|rcsb pdb:4OZH|rcsb pdb:4OZI|rcsb pdb:4PRH|rcsb pdb:4PRI|rcsb pdb:4PRP|rcsb pdb:3D39|rcsb pdb:3HE6|rcsb pdb:3KPR|rcsb pdb:4GG6|rcsb pdb:4GG8|rcsb pdb:4L4V|rcsb pdb:2BNQ|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003597(Immunoglobulin C1-set)|rcsb pdb:1FYT|rcsb pdb:1J8H|rcsb pdb:1KGC|rcsb pdb:1KTK|rcsb pdb:1MI5|rcsb pdb:1OGA|rcsb pdb:1YMM|rcsb pdb:1ZGL|rcsb pdb:2AK4|rcsb pdb:2AXH|rcsb pdb:2BNR|rcsb pdb:2BNU|rcsb pdb:2ESV|rcsb pdb:2F53|rcsb pdb:2F54|rcsb pdb:2GJ6|rcsb pdb:2IAL|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2NTS|rcsb pdb:2NW2|rcsb pdb:2NX5|rcsb pdb:2P5E|rcsb pdb:2P5W|rcsb pdb:2PO6|rcsb pdb:2PYE|rcsb pdb:2PYF|rcsb pdb:2VLJ|rcsb pdb:2VLK|rcsb pdb:2VLM|rcsb pdb:2VLR|rcsb pdb:2XN9|rcsb pdb:2XNA|rcsb pdb:3DX9|rcsb pdb:3DXA|rcsb pdb:3FFC|rcsb pdb:4ZDH|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|rcsb pdb:4G8E|rcsb pdb:4G8F|rcsb pdb:4IIQ|rcsb pdb:4JRX|rcsb pdb:4JRY|rcsb pdb:4MJI|rcsb pdb:4P46|rcsb pdb:4X6B|rcsb pdb:4X6C|rcsb pdb:4X6D|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948|rcsb pdb:4JFD|rcsb pdb:4JFE|rcsb pdb:4JFF|rcsb pdb:4JFH|rcsb pdb:2CDE|rcsb pdb:2CDF|rcsb pdb:2CDG|rcsb pdb:3ARB|rcsb pdb:3ARD|rcsb pdb:3ARE|rcsb pdb:3ARF|rcsb pdb:3ARG|rcsb pdb:3O4L|rcsb pdb:1AO7|rcsb pdb:3HG1|rcsb pdb:3KPS|rcsb pdb:3TN0|rcsb pdb:4L4T|interpro:IPR036179	-	-	-	assembly:pentameric, multimeric|3d-r-factors:working 78.900%, free 75.400%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2021/02/11	rogid:NCr/6W1ldQuOhlyWUW4aTnhmKKY9606	rogid:tLvWuE6FRB59QPlPL99jKQFkiuQ9606	intact-crc:F9FA9F165B801189|rigid:257IQ6GyDSMtf3Ny02FQT9gdfnM	false	sufficient binding region:26-206	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)