#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36630 uniprotkb:P41412 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:"MI:0096"(pull down) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149191|imex:IM-19512-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N - - crc64:1159312B63E475E4 figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/30 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 intact-crc:2EF31F048B3DA6B2|rigid:1Ybmw0F1RrZbuwJArLW/iuOAdQo false 35s radiolabel:?-? maltose binding protein tag:n-n|sufficient binding region:1-147 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36630 uniprotkb:P41412 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149259|imex:IM-19512-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N - - crc64:1159312B63E475E4 figure legend:Fig. 3B, 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 intact-crc:6BB46CEA8B8F38E1|rigid:1Ybmw0F1RrZbuwJArLW/iuOAdQo false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41412 uniprotkb:P01129 intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" intact:EBI-1009350|uniprotkb:Q9UU04|ensemblfungi:"SPBC336.12c.1:pep" psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:cdc10_schpo(display_long)|uniprotkb:cdc10(gene name)|psi-mi:cdc10(display_short)|uniprotkb:SPBC336.12c(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149285|imex:IM-19512-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N refseq:NP_596132.1|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|ensemblfungi:SPBC336.12c(gene)|ensemblfungi:SPBC336.12c.1(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009303"(rRNA transcription)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR036770|interpro:IPR036887|dip:DIP-353N - crc64:1159312B63E475E4 crc64:0E514EE1BE218EFA figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 rogid:3uQ3wPJ5PLO3N2b6Tch1q+nfc8M284812 intact-crc:FAB7101C219D9C32|rigid:meKKxaf/byrKKlmpu4K7SvXnCTI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41412 uniprotkb:P33520 intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" intact:EBI-1149288|ensemblfungi:"SPBC725.16.1:pep" psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:res1_schpo(display_long)|uniprotkb:res1(gene name)|psi-mi:res1(display_short)|uniprotkb:sct1(gene name synonym)|uniprotkb:SPBC725.16(orf name)|uniprotkb:p72sct1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149303|imex:IM-19512-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N refseq:NP_595496.1|ensemblfungi:SPBC725.16(gene)|ensemblfungi:SPBC725.16.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-210N - crc64:1159312B63E475E4 - figure legend:Fig. 3B, 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 rogid:coc4pLAyvaoErfrKBc01I8VZEVI284812 intact-crc:935C82FB008D5903|rigid:ABZfM8V87t9ad70MEgWfW6XVTh0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P41412 uniprotkb:P33520 intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" intact:EBI-1149288|ensemblfungi:"SPBC725.16.1:pep" psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:res1_schpo(display_long)|uniprotkb:res1(gene name)|psi-mi:res1(display_short)|uniprotkb:sct1(gene name synonym)|uniprotkb:SPBC725.16(orf name)|uniprotkb:p72sct1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149309|imex:IM-19512-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N refseq:NP_595496.1|ensemblfungi:SPBC725.16(gene)|ensemblfungi:SPBC725.16.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-210N - crc64:1159312B63E475E4 - figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 rogid:coc4pLAyvaoErfrKBc01I8VZEVI284812 intact-crc:6AC94B51E6219F1C|rigid:ABZfM8V87t9ad70MEgWfW6XVTh0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36630 uniprotkb:P33520 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1149288|ensemblfungi:"SPBC725.16.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:res1_schpo(display_long)|uniprotkb:res1(gene name)|psi-mi:res1(display_short)|uniprotkb:sct1(gene name synonym)|uniprotkb:SPBC725.16(orf name)|uniprotkb:p72sct1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149313|imex:IM-19512-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:NP_595496.1|ensemblfungi:SPBC725.16(gene)|ensemblfungi:SPBC725.16.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-210N - - - figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:coc4pLAyvaoErfrKBc01I8VZEVI284812 intact-crc:33D92AA97A1338E8|rigid:qvKVIuwctrQxGCsv45yBiryEWHY false ha tag:c-c mutation increasing interaction:130-130 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P36630 uniprotkb:P41412 intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" intact:EBI-1149177|uniprotkb:Q02300|ensemblfungi:"SPAC22F3.09c.1:pep" psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:res2_schpo(display_long)|uniprotkb:res2(gene name)|psi-mi:res2(display_short)|uniprotkb:pct1(gene name synonym)|uniprotkb:SPAC22F3.09c(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149323|imex:IM-19512-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 refseq:NP_593032.1|ensemblfungi:SPAC22F3.09c(gene)|ensemblfungi:SPAC22F3.09c.1(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-35569N - - crc64:1159312B63E475E4 figure legend:Fig. 4E|comment:"Interaction occurs in the presence of mutant ser130ala res1 protein (AC P33520)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 rogid:Bt8hchyEhUudF6B8+g/Vna0gU/s284812 intact-crc:2C24CE25B0DEAC31|rigid:1Ybmw0F1RrZbuwJArLW/iuOAdQo false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P33520 uniprotkb:P36630 intact:EBI-1149288|ensemblfungi:"SPBC725.16.1:pep" intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" psi-mi:res1_schpo(display_long)|uniprotkb:res1(gene name)|psi-mi:res1(display_short)|uniprotkb:sct1(gene name synonym)|uniprotkb:SPBC725.16(orf name)|uniprotkb:p72sct1(gene name synonym) psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1149333|imex:IM-19512-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_595496.1|ensemblfungi:SPBC725.16(gene)|ensemblfungi:SPBC725.16.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-210N refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 - - - figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2006/10/30 2014/10/16 rogid:coc4pLAyvaoErfrKBc01I8VZEVI284812 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 intact-crc:B11FEFF319E1AABA|rigid:qvKVIuwctrQxGCsv45yBiryEWHY false mutation increasing interaction:130-130 ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P33520 uniprotkb:P36630 intact:EBI-1149288|ensemblfungi:"SPBC725.16.1:pep" intact:EBI-1149212|ensemblfungi:"SPAPB2B4.03.1:pep" psi-mi:res1_schpo(display_long)|uniprotkb:res1(gene name)|psi-mi:res1(display_short)|uniprotkb:sct1(gene name synonym)|uniprotkb:SPBC725.16(orf name)|uniprotkb:p72sct1(gene name synonym) psi-mi:cg22_schpo(display_long)|uniprotkb:cig2(gene name)|psi-mi:cig2(display_short)|uniprotkb:cyc17(gene name synonym)|uniprotkb:SPAPB2B4.03(orf name) psi-mi:"MI:0423"(in-gel kinase assay) Ayte et al. (2001) pubmed:11781565|imex:IM-19512 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0486"(UniProt) intact:EBI-1167935|imex:IM-19512-9 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_595496.1|ensemblfungi:SPBC725.16(gene)|ensemblfungi:SPBC725.16.1(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR003163(DNA-binding, yeast)|interpro:IPR018004|interpro:IPR029793|interpro:IPR036770|interpro:IPR036887|dip:DIP-210N refseq:NP_593889.1|interpro:IPR013763(Cyclin-related)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0006310"(DNA recombination)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0031138"(negative regulation of conjugation with cellular fusion)|go:"GO:0031568"(mitotic G1 cell size control checkpoint signaling)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0110044"(regulation of cell cycle switching, mitotic to meiotic cell cycle)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR039361|ensemblfungi:SPAPB2B4.03(gene)|ensemblfungi:SPAPB2B4.03.1(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000746"(conjugation)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR036915|reactome:R-SPO-5687128|reactome:R-SPO-5689880|reactome:R-SPO-68949|reactome:R-SPO-69656|reactome:R-SPO-75815|reactome:R-SPO-8951664|reactome:R-SPO-983168|reactome:R-SPO-69017|reactome:R-SPO-69202 - - - figure legend:Fig. 4A, 4B|inhibition:Phosphorylation is inhibited by Rum1.|agonist:Phosphorylation is stimulated by hydroxyurea treatment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/10/30 2014/10/16 rogid:coc4pLAyvaoErfrKBc01I8VZEVI284812 rogid:jy0L9N93HkOpYT6A/7S3SFUUeQg284812 intact-crc:2E17850BDFB8B123|rigid:qvKVIuwctrQxGCsv45yBiryEWHY false mutation disrupting interaction:130-130|sufficient binding region:1-192|glutathione s tranferase tag:n-n ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)