#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O94556	uniprotkb:P50528	intact:EBI-1116472|ensemblfungi:"SPAC6F12.14.1:pep"	intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep"	psi-mi:apc8_schpo(display_long)|uniprotkb:cut23(gene name)|psi-mi:cut23(display_short)|uniprotkb:apc8(gene name synonym)|uniprotkb:SPAC6F12.14(orf name)|uniprotkb:20S cyclosome/APC complex protein apc8(gene name synonym)|uniprotkb:Cell untimely torn protein 23(gene name synonym)	psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name)	psi-mi:"MI:0018"(two hybrid)	May et al. (2002)	pubmed:11777938	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1148019	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3ZN3|rcsb pdb:5FTP|ensemblfungi:SPAC6F12.14(gene)|ensemblfungi:SPAC6F12.14.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|refseq:NP_593300.1|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SPO-983168	refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025	-	-	crc64:F11CD0EF9B913917	figure legend:Fig 4C, 4D, 5B	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/10/26	2014/10/16	rogid:1VGixeW3PZla68diUHg/2d+aSwA284812	rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812	intact-crc:C6582965F9988FC8|rigid:NR5xODAUbZrXtRD1DkpNCFWJ5Jg	false	sufficient binding region:1-473|mutation decreasing interaction:349-349|necessary binding region:1-50|necessary binding region:440-565	necessary binding region:584-683|sufficient binding region:313-683|binding-associated region:508-510	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50528	uniprotkb:O94556	intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep"	intact:EBI-1116472|ensemblfungi:"SPAC6F12.14.1:pep"	psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name)	psi-mi:apc8_schpo(display_long)|uniprotkb:cut23(gene name)|psi-mi:cut23(display_short)|uniprotkb:apc8(gene name synonym)|uniprotkb:SPAC6F12.14(orf name)|uniprotkb:20S cyclosome/APC complex protein apc8(gene name synonym)|uniprotkb:Cell untimely torn protein 23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	May et al. (2002)	pubmed:11777938	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1148027	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025	rcsb pdb:3ZN3|rcsb pdb:5FTP|ensemblfungi:SPAC6F12.14(gene)|ensemblfungi:SPAC6F12.14.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|refseq:NP_593300.1|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SPO-983168	-	crc64:F11CD0EF9B913917	-	figure legend:Fig. 3A	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/26	2014/10/16	rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812	rogid:1VGixeW3PZla68diUHg/2d+aSwA284812	intact-crc:68AA9D085EA327FB|rigid:NR5xODAUbZrXtRD1DkpNCFWJ5Jg	false	-	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P50528	uniprotkb:O94556	intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep"	intact:EBI-1116472|ensemblfungi:"SPAC6F12.14.1:pep"	psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name)	psi-mi:apc8_schpo(display_long)|uniprotkb:cut23(gene name)|psi-mi:cut23(display_short)|uniprotkb:apc8(gene name synonym)|uniprotkb:SPAC6F12.14(orf name)|uniprotkb:20S cyclosome/APC complex protein apc8(gene name synonym)|uniprotkb:Cell untimely torn protein 23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	May et al. (2002)	pubmed:11777938	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1148039	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025	rcsb pdb:3ZN3|rcsb pdb:5FTP|ensemblfungi:SPAC6F12.14(gene)|ensemblfungi:SPAC6F12.14.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|refseq:NP_593300.1|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SPO-983168	-	crc64:F11CD0EF9B913917	-	figure legend:Fig. 3B, 4A	taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)")	-	2006/10/26	2014/10/16	rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812	rogid:1VGixeW3PZla68diUHg/2d+aSwA284812	intact-crc:4422851CD9E33EBC|rigid:NR5xODAUbZrXtRD1DkpNCFWJ5Jg	false	-	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94556	uniprotkb:P50528	intact:EBI-1116472|ensemblfungi:"SPAC6F12.14.1:pep"	intact:EBI-1112601|ensemblfungi:"SPAC23C11.16.1:pep"	psi-mi:apc8_schpo(display_long)|uniprotkb:cut23(gene name)|psi-mi:cut23(display_short)|uniprotkb:apc8(gene name synonym)|uniprotkb:SPAC6F12.14(orf name)|uniprotkb:20S cyclosome/APC complex protein apc8(gene name synonym)|uniprotkb:Cell untimely torn protein 23(gene name synonym)	psi-mi:plo1_schpo(display_long)|uniprotkb:plo1(gene name)|psi-mi:plo1(display_short)|uniprotkb:SPAC23C11.16(orf name)	psi-mi:"MI:0096"(pull down)	May et al. (2002)	pubmed:11777938	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1148050	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:3ZN3|rcsb pdb:5FTP|ensemblfungi:SPAC6F12.14(gene)|ensemblfungi:SPAC6F12.14.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|refseq:NP_593300.1|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|reactome:R-SPO-983168	refseq:NP_593647.1|ensemblfungi:SPAC23C11.16(gene)|ensemblfungi:SPAC23C11.16.1(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005829"(cytosol)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0010973"(positive regulation of division septum assembly)|go:"GO:0031031"(positive regulation of septation initiation signaling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035974"(meiotic spindle pole body)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051301"(cell division)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140434"(positive regulation of protein localization to meiotic spindle pole body)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902542"(regulation of protein localization to mitotic spindle pole body)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990813"(meiotic centromeric cohesion protection)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|reactome:R-SPO-156711|reactome:R-SPO-162658|reactome:R-SPO-2500257|reactome:R-SPO-2565942|reactome:R-SPO-68884|dip:DIP-35381N|reactome:R-SPO-6804115|reactome:R-SPO-9648025	-	-	crc64:F11CD0EF9B913917	figure legend:Fig. 3C	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/10/26	2014/10/16	rogid:1VGixeW3PZla68diUHg/2d+aSwA284812	rogid:b9BjDOB+1fQLQ8e/Lv5YLaF+zME284812	intact-crc:E95391D3CDA2DE34|rigid:NR5xODAUbZrXtRD1DkpNCFWJ5Jg	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)