#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O73798	uniprotkb:Q5HZ83	intact:EBI-8068109|intact:MINT-609362	intact:EBI-8068143|intact:MINT-609378	psi-mi:igf1r_xenla(display_long)|uniprotkb:igf1r(gene name)|psi-mi:igf1r(display_short)	psi-mi:q5hz83_xenla(display_long)|uniprotkb:gipc2.S(gene name)|psi-mi:gipc2.S(display_short)|uniprotkb:GIPC(gene name synonym)|uniprotkb:gipc2(gene name synonym)|uniprotkb:XELAEV_18025065mg(orf name)	psi-mi:"MI:0018"(two hybrid)	Booth et al. (2002)	pubmed:11751850|mint:MINT-5214969	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068153|mint:MINT-73454	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001081734.1|interpro:IPR016246(Insulin receptor)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR011009(Protein kinase-like)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR036116|interpro:IPR036941|go:"GO:0001556"(oocyte maturation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|mint:MINT-609385(identity)	interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|refseq:NP_001082286.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:MINT-609394(identity)	-	comment:mint|function:"This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. Plays a role in oocyte maturation. Promotes head development by inhibiting Wnt signaling during embryogenesis"|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/01/11	2014/10/16	rogid:h2TiONWYXECnNMDL228RkSNGm+I8355	rogid:vdaEISy66InnNba2ohWX20czT6A8355	intact-crc:9398F80D04222300|rigid:rLXZGJthxZVjOW3iyboR869GHYg	false	binding-associated region:958-1358(MINT-609386)|ha tag:?-?(MINT-609388)	tag:?-?(MINT-609397)|binding-associated region:1-232(MINT-609395)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O73798	uniprotkb:Q5HZ83	intact:EBI-8068109|intact:MINT-609362	intact:EBI-8068143|intact:MINT-609378	psi-mi:igf1r_xenla(display_long)|uniprotkb:igf1r(gene name)|psi-mi:igf1r(display_short)	psi-mi:q5hz83_xenla(display_long)|uniprotkb:gipc2.S(gene name)|psi-mi:gipc2.S(display_short)|uniprotkb:GIPC(gene name synonym)|uniprotkb:gipc2(gene name synonym)|uniprotkb:XELAEV_18025065mg(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Booth et al. (2002)	pubmed:11751850|mint:MINT-5214969	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8068232|mint:MINT-73455	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001081734.1|interpro:IPR016246(Insulin receptor)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR011009(Protein kinase-like)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002011(Receptor tyrosine kinase, class II, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR036116|interpro:IPR036941|go:"GO:0001556"(oocyte maturation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|mint:MINT-609408(identity)	interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|refseq:NP_001082286.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:MINT-609415(identity)	-	comment:mint|function:"This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. Plays a role in oocyte maturation. Promotes head development by inhibiting Wnt signaling during embryogenesis"|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2006/01/11	2014/10/16	rogid:h2TiONWYXECnNMDL228RkSNGm+I8355	rogid:vdaEISy66InnNba2ohWX20czT6A8355	intact-crc:A72300BD06692804|rigid:rLXZGJthxZVjOW3iyboR869GHYg	false	myc tag:?-?(MINT-609409)	binding-associated region:1-320(MINT-609416)|ha tag:?-?(MINT-609418)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)