#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03255 uniprotkb:Q15326 intact:EBI-2603114|uniprotkb:P06438|uniprotkb:Q64825|uniprotkb:Q64826 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 psi-mi:e1a_ade05(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym) psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:"MI:0096"(pull down) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052886|mint:MINT-2575948 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:AP_000197.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR014410(Adenovirus early E1A)|rcsb pdb:2KJE|rcsb pdb:2R7G|rcsb pdb:6H6D|rcsb pdb:6H6H|go:"GO:0042025"(host cell nucleus)|dip:DIP-40736N|mint:P03255|mint:MINT-2575949(identity) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1|mint:MINT-2575950(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/14 2014/10/16 rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 intact-crc:7A8B17493711B036|rigid:MltgBWpyOLmRJsiL0ClGEsvD+WE false binding-associated region:86-128(MINT-2983756) glutathione s tranferase tag:?-?(MINT-2576146)|mutation disrupting interaction:563-563(MINT-2576153)|binding-associated region:558-602(MINT-2576151) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12978 uniprotkb:Q15326 intact:EBI-8052923|uniprotkb:Q777H1|intact:MINT-2576568|uniprotkb:Q69023 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 psi-mi:ebna2_ebvb9(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:"MI:0096"(pull down) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052916|mint:MINT-2576531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401644.1|mint:P12978|dip:DIP-41174N|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060153"(modulation by virus of host cell cycle)|rcsb pdb:2MKR|rcsb pdb:2N2J|rcsb pdb:5HDA|go:"GO:0019056"(modulation by virus of host transcription)|mint:MINT-2576532(identity) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1|mint:MINT-2576536(identity) - comment:mint|function:Involved in latent cycle. Transactivates the expression of LMP-1|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/14 2014/10/16 rogid:NFW1UkIAeAdFQXUOC7vT8XKGxes10377 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 intact-crc:BD5A35B6CDEC29B5|rigid:qq37Tf1zy4YWiXTDMvqgBTgcjDA false binding-associated region:379-439(MINT-2583869) glutathione s tranferase tag:?-?(MINT-2576549)|mutation disrupting interaction:563-563(MINT-2576537)|mutation disrupting interaction:451-557(MINT-2576540)|binding-associated region:451-602(MINT-2576543) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20747 uniprotkb:P12978 intact:EBI-8052986|intact:MINT-2578472|ensemblmetazoa:F54B11.11.1 intact:EBI-8052923|uniprotkb:Q777H1|intact:MINT-2576568|uniprotkb:Q69023 psi-mi:q20747_caeel(display_long)|uniprotkb:F54B11.11(orf name)|uniprotkb:CELE_F54B11.11(orf name) psi-mi:ebna2_ebvb9(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:"MI:0096"(pull down) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8053015|mint:MINT-2578612 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F54B11.11|mint:Q20747|ensemblmetazoa:F54B11.11.1(transcript)|ensemblmetazoa:WBGene00010034(gene)|go:"GO:0045087"(innate immune response)|interpro:IPR003366(CUB-like region)|refseq:NP_510270.1|mint:MINT-2578613(identity) refseq:YP_401644.1|mint:P12978|dip:DIP-41174N|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060153"(modulation by virus of host cell cycle)|rcsb pdb:2MKR|rcsb pdb:2N2J|rcsb pdb:5HDA|go:"GO:0019056"(modulation by virus of host transcription)|mint:MINT-2578621(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:Involved in latent cycle. Transactivates the expression of LMP-1|comment:"Stoichiometry: 1.0" figure legend:F1E|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/14 2019/08/05 rogid:/6Do/2shzSNk4Egpxlb49F0V9RQ6239 rogid:NFW1UkIAeAdFQXUOC7vT8XKGxes10377 intact-crc:EFAC9AA63CEB15F3|rigid:0mSCKdmaD4OMr0YvlhEpjO+wasU false glutathione s tranferase tag:?-?(MINT-2578617)|binding-associated region:117-163(MINT-2578614) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20747 uniprotkb:P03255 intact:EBI-8052986|intact:MINT-2578472|ensemblmetazoa:F54B11.11.1 intact:EBI-2603114|uniprotkb:P06438|uniprotkb:Q64825|uniprotkb:Q64826 psi-mi:q20747_caeel(display_long)|uniprotkb:F54B11.11(orf name)|uniprotkb:CELE_F54B11.11(orf name) psi-mi:e1a_ade05(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8052997|mint:MINT-2578413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:F54B11.11|mint:Q20747|ensemblmetazoa:F54B11.11.1(transcript)|ensemblmetazoa:WBGene00010034(gene)|go:"GO:0045087"(innate immune response)|interpro:IPR003366(CUB-like region)|refseq:NP_510270.1|mint:MINT-2578418(identity) refseq:AP_000197.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR014410(Adenovirus early E1A)|rcsb pdb:2KJE|rcsb pdb:2R7G|rcsb pdb:6H6D|rcsb pdb:6H6H|go:"GO:0042025"(host cell nucleus)|dip:DIP-40736N|mint:P03255|mint:MINT-2578414(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1E|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/14 2019/08/05 rogid:/6Do/2shzSNk4Egpxlb49F0V9RQ6239 rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285 intact-crc:322FD17888E9D1D2|rigid:sC9mWLRLiuEwPgr9RC9BwYW6QvQ false binding-associated region:117-163(MINT-2578425)|glutathione s tranferase tag:?-?(MINT-2578430) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O01914 uniprotkb:P03255 intact:EBI-2416528|ensemblmetazoa:F23H11.2.1 intact:EBI-2603114|uniprotkb:P06438|uniprotkb:Q64825|uniprotkb:Q64826 psi-mi:taf1b_caeel(display_long)|uniprotkb:TATA box-binding protein-associated factor 1B(gene name synonym)|uniprotkb:F23H11.2(orf name) psi-mi:e1a_ade05(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym) psi-mi:"MI:0096"(pull down) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8053051|mint:MINT-2578735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR021752|refseq:NP_497287.2|wormbase:F23H11.2|interpro:IPR033599|mint:O01914|ensemblmetazoa:F23H11.2.1(transcript)|ensemblmetazoa:WBGene00017758(gene)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0005668"(RNA polymerase transcription factor SL1 complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0070860"(RNA polymerase I core factor complex)|reactome:R-CEL-73772|mint:MINT-2578739(identity) refseq:AP_000197.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR014410(Adenovirus early E1A)|rcsb pdb:2KJE|rcsb pdb:2R7G|rcsb pdb:6H6D|rcsb pdb:6H6H|go:"GO:0042025"(host cell nucleus)|dip:DIP-40736N|mint:P03255|mint:MINT-2578748(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1E|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/14 2014/10/16 rogid:xpiMj+KtKhp7YQt6WU0buNrcGZg6239 rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285 intact-crc:99A3A244E6B984D8|rigid:rAd4uQBXwMd3Zp4dZ77LHrsz5eE false glutathione s tranferase tag:?-?(MINT-2578744)|binding-associated region:144-189(MINT-2578741) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12978 uniprotkb:O01914 intact:EBI-8052923|uniprotkb:Q777H1|intact:MINT-2576568|uniprotkb:Q69023 intact:EBI-2416528|ensemblmetazoa:F23H11.2.1 psi-mi:ebna2_ebvb9(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:taf1b_caeel(display_long)|uniprotkb:TATA box-binding protein-associated factor 1B(gene name synonym)|uniprotkb:F23H11.2(orf name) psi-mi:"MI:0096"(pull down) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8053033|mint:MINT-2578691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401644.1|mint:P12978|dip:DIP-41174N|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060153"(modulation by virus of host cell cycle)|rcsb pdb:2MKR|rcsb pdb:2N2J|rcsb pdb:5HDA|go:"GO:0019056"(modulation by virus of host transcription)|mint:MINT-2578692(identity) interpro:IPR021752|refseq:NP_497287.2|wormbase:F23H11.2|interpro:IPR033599|mint:O01914|ensemblmetazoa:F23H11.2.1(transcript)|ensemblmetazoa:WBGene00017758(gene)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0005668"(RNA polymerase transcription factor SL1 complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0070860"(RNA polymerase I core factor complex)|reactome:R-CEL-73772|mint:MINT-2578696(identity) - comment:mint|function:Involved in latent cycle. Transactivates the expression of LMP-1|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1E|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/14 2014/10/16 rogid:NFW1UkIAeAdFQXUOC7vT8XKGxes10377 rogid:xpiMj+KtKhp7YQt6WU0buNrcGZg6239 intact-crc:B4B70F7D654A9882|rigid:KR1PAdsxU4a6+S3Hjd80tp+1gJM false - glutathione s tranferase tag:?-?(MINT-2578699)|binding-associated region:144-189(MINT-2578702) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15326 uniprotkb:P03255 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-2603114|uniprotkb:P06438|uniprotkb:Q64825|uniprotkb:Q64826 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:e1a_ade05(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8053149|mint:MINT-2577206 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1|mint:MINT-2577211(identity) refseq:AP_000197.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0046719"(regulation by virus of viral protein levels in host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR014410(Adenovirus early E1A)|rcsb pdb:2KJE|rcsb pdb:2R7G|rcsb pdb:6H6D|rcsb pdb:6H6H|go:"GO:0042025"(host cell nucleus)|dip:DIP-40736N|mint:P03255|mint:MINT-2577207(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-qt_6)|taxid:9606(Homo sapiens) - 2006/06/14 2014/10/16 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:Yj7851FOR0yCEZBF540O97/Oo/M28285 intact-crc:D0EE1E3CD8AD9604|rigid:MltgBWpyOLmRJsiL0ClGEsvD+WE false flag tag:?-?(MINT-2577223)|mutation disrupting interaction:563-563(MINT-2577212)|binding-associated region:451-602(MINT-2577218) mutation disrupting interaction:115-115(MINT-2583877) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q15326 uniprotkb:P03255-2 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-6859460|intact:EBI-7796221|intact:EBI-8665485|intact:EBI-7796198|intact:EBI-6996423|intact:EBI-7427771|intact:EBI-8679750|intact:EBI-8544261|intact:EBI-8646018|intact:EBI-8646062|intact:EBI-8646168|intact:EBI-7427730|intact:EBI-8053186|intact:EBI-8645976|intact:EBI-8646143|intact:EBI-8665537|intact:EBI-7427512|intact:EBI-8544381|intact:MINT-87562|intact:EBI-8544435|intact:EBI-8679721|intact:EBI-8665366|intact:EBI-7140610|intact:EBI-8646114|intact:EBI-8665567|intact:EBI-7140682|intact:EBI-8544418 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:p03255-2(display_long)|uniprotkb:Early E1A 32 kDa protein(gene name synonym)|uniprotkb:243R(isoform synonym)|uniprotkb:S-E1A(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:28285(ade05)|taxid:28285("Human adenovirus C serotype 5 (HAdV-5)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8053180|mint:MINT-2583884 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1|mint:MINT-2583893(identity) intact:EBI-2603114(isoform-parent)|mint:MINT-2583885(identity) - comment:"Stoichiometry: 1.0" isoform-comment:No experimental confirmation available.|comment:"Stoichiometry: 1.0" figure legend:F3A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-qt_6)|taxid:9606(Homo sapiens) - 2006/06/14 2014/10/16 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:3OSlEpVJ8y6MDaS6uIIUi38tgKM28285 intact-crc:7545876D02A0BC1F|rigid:M11FeGVIFEk3fSsDKQ/p8qQ/ax8 false flag tag:?-?(MINT-2583902)|binding-associated region:451-602(MINT-2583897) mutation disrupting interaction:115-115(MINT-2583886) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P12978 uniprotkb:Q15326 intact:EBI-8052923|uniprotkb:Q777H1|intact:MINT-2576568|uniprotkb:Q69023 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 psi-mi:ebna2_ebvb9(display_long)|uniprotkb:EBNA2(gene name)|psi-mi:EBNA2(display_short)|uniprotkb:BYRF1(orf name) psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ansieau et al. (2002) pubmed:11733528|mint:MINT-5214864 taxid:10377(ebvb9)|taxid:10377("Epstein-Barr virus (strain B95-8) (HHV-4)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8053239|mint:MINT-2577583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_401644.1|mint:P12978|dip:DIP-41174N|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044204"(host cell nuclear matrix)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0060153"(modulation by virus of host cell cycle)|rcsb pdb:2MKR|rcsb pdb:2N2J|rcsb pdb:5HDA|go:"GO:0019056"(modulation by virus of host transcription)|mint:MINT-2577596(identity) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1|mint:MINT-2577584(identity) - comment:mint|function:Involved in latent cycle. Transactivates the expression of LMP-1|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2006/06/14 2014/10/16 rogid:NFW1UkIAeAdFQXUOC7vT8XKGxes10377 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 intact-crc:7346201A24480E9B|rigid:qq37Tf1zy4YWiXTDMvqgBTgcjDA false - flag tag:?-?(MINT-2577593) 1 1 psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)