#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P49735 uniprotkb:Q26454 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875853 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 intact-crc:09B45F61C70AF445|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49735 uniprotkb:Q9XYU1 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875853 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 intact-crc:09B45F61C70AF445|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49735 uniprotkb:Q9VGW6 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875853 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 intact-crc:09B45F61C70AF445|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P49735 uniprotkb:Q9V461 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875853 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 intact-crc:09B45F61C70AF445|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:P49735 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875859 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:D25B63920BDCF397|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q26454 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875859 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 intact-crc:D25B63920BDCF397|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q9XYU1 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875859 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 intact-crc:D25B63920BDCF397|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q9VGW6 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875859 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 go:"GO:0000785"(chromatin) - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 intact-crc:D25B63920BDCF397|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:Q9V461 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875865 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0000785"(chromatin) - - comment:MCM5 antibody was only able to co-precipitate MCM3 in near equimolar amounts. The other MCMs could also be detected in the immunoprecipitate, but in much lower amounts. It was assumed this is because the MCM5 antibody partially disrupts the complex. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 intact-crc:CB20EEE9A6CEB02E|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:Q26454 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875865 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0000785"(chromatin) - - comment:MCM5 antibody was only able to co-precipitate MCM3 in near equimolar amounts. The other MCMs could also be detected in the immunoprecipitate, but in much lower amounts. It was assumed this is because the MCM5 antibody partially disrupts the complex. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 intact-crc:CB20EEE9A6CEB02E|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:P49735 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875865 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N go:"GO:0000785"(chromatin) - - comment:MCM5 antibody was only able to co-precipitate MCM3 in near equimolar amounts. The other MCMs could also be detected in the immunoprecipitate, but in much lower amounts. It was assumed this is because the MCM5 antibody partially disrupts the complex. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:CB20EEE9A6CEB02E|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:Q9XYU1 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875865 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 go:"GO:0000785"(chromatin) - - comment:MCM5 antibody was only able to co-precipitate MCM3 in near equimolar amounts. The other MCMs could also be detected in the immunoprecipitate, but in much lower amounts. It was assumed this is because the MCM5 antibody partially disrupts the complex. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 intact-crc:CB20EEE9A6CEB02E|rigid:ew8vdA/PATWKeo8bpxB+FV8WEy4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:P49735 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-875872 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N go:"GO:0000785"(chromatin) - - comment:The immuno-adsorbed complexes were washed in RIPA buffer containing 0.1% SDS and 1% Triton X-100 prior to elution in order to retain only the more tightly bound partners. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:DE5EA772BE27C6E1|rigid:5GlSclzxedJoNe2T3JMaX2zIjPo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:Q9XYU1 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-875882 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 go:"GO:0000785"(chromatin) - - comment:The immuno-adsorbed complexes were washed in RIPA buffer containing 0.1% SDS and 1% Triton X-100 prior to elution in order to retain only the more tightly bound partners. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 intact-crc:040FE8DA21D1640F|rigid:AeZH/CwvsxPS9HuyVLCB9lCZ/qM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q26454 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875891 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0000785"(chromatin) - - comment:The immuno-adsorbed complexes were washed in RIPA buffer containing 0.1% SDS and 1% Triton X-100 prior to elution in order to retain only the more tightly bound partners. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 intact-crc:E9EE14A2F32E336D|rigid:WSiNIEJEVoksPOnDNBUroZPIQbs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:P49735 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-875891 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N go:"GO:0000785"(chromatin) - - comment:The immuno-adsorbed complexes were washed in RIPA buffer containing 0.1% SDS and 1% Triton X-100 prior to elution in order to retain only the more tightly bound partners. taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:E9EE14A2F32E336D|rigid:WSiNIEJEVoksPOnDNBUroZPIQbs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q26454 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-872542 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 - - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 intact-crc:2AFD9FEC892C840E|rigid:f1jNsDJBhsw+jtZyQk3HDp64xX4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:P49735 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-873594 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N - - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:C2F401D568E4EE82|rigid:5GlSclzxedJoNe2T3JMaX2zIjPo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:P49735 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-873598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N - - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 intact-crc:DC29B8D0E32FC67B|rigid:dTr8NdNXtSV5zKLJE3+RIrMCjPQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VGW6 uniprotkb:Q9XYU1 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Crevel et al. (2001) pubmed:11726693 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-873602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 - - - - taxid:7227(drome-embryo)|taxid:7227(drosophilla melanogaster embryo) - 2006/03/03 2014/10/16 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 intact-crc:90ABF3A8391C8E6D|rigid:AeZH/CwvsxPS9HuyVLCB9lCZ/qM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)