#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P62593 uniprotkb:P35804 intact:EBI-1031989|uniprotkb:P00810|uniprotkb:Q47313 intact:EBI-1031985 psi-mi:blat_ecolx(display_long)|uniprotkb:bla(gene name)|psi-mi:bla(display_short)|uniprotkb:blaT-3(gene name)|psi-mi:blaT-3(display_short)|uniprotkb:blaT-4(gene name)|psi-mi:blaT-4(display_short)|uniprotkb:blaT-5(gene name)|psi-mi:blaT-5(display_short)|uniprotkb:blaT-6(gene name)|psi-mi:blaT-6(display_short)|uniprotkb:TEM-1(gene name synonym)|uniprotkb:TEM-2(gene name synonym)|uniprotkb:TEM-3(gene name synonym)|uniprotkb:TEM-4(gene name synonym)|uniprotkb:TEM-5(gene name synonym)|uniprotkb:TEM-6(gene name synonym)|uniprotkb:TEM-8/CAZ-2(gene name synonym)|uniprotkb:TEM-16/CAZ-7(gene name synonym)|uniprotkb:TEM-24/CAZ-6(gene name synonym)|uniprotkb:IRT-4(gene name synonym)|uniprotkb:Penicillinase(gene name synonym) psi-mi:blip_strcl(display_long) psi-mi:"MI:0114"(x-ray crystallography) Lim et al. (2001) pubmed:11573088 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:1901(strcl)|taxid:1901(Streptomyces clavuligerus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1032008|rcsb pdb:1JTG - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_008864019.1|refseq:YP_008864686.1|refseq:YP_008995211.1|refseq:YP_007447512.1|rcsb pdb:4ID4|refseq:YP_003829069.1|refseq:YP_003829170.1|refseq:YP_003937675.1|refseq:YP_004119720.1|refseq:YP_004119734.1|refseq:YP_190222.1|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR000871(Beta-lactamase, class A)|rcsb pdb:6AYK|rcsb pdb:4DXB|rcsb pdb:4DXC|refseq:NP_943295.1|refseq:NP_957565.1|refseq:YP_001693174.1|refseq:YP_003108102.1|refseq:YP_003108210.1|rcsb pdb:4MEZ|refseq:YP_009060387.1|refseq:YP_009060444.1|refseq:YP_009060580.1|refseq:YP_009061316.1|refseq:YP_009066523.1|refseq:YP_009068284.1|refseq:YP_009068507.1|refseq:YP_009070232.1|refseq:YP_009070558.1|refseq:YP_009071512.1|interpro:IPR023650|rcsb pdb:1AXB|rcsb pdb:1BT5|rcsb pdb:1BTL|rcsb pdb:1CK3|rcsb pdb:1ERM|rcsb pdb:1ERO|rcsb pdb:1ERQ|rcsb pdb:1ESU|rcsb pdb:1FQG|rcsb pdb:1JTD|rcsb pdb:1JTG|rcsb pdb:1JVJ|rcsb pdb:1JWP|rcsb pdb:1JWV|rcsb pdb:1JWZ|rcsb pdb:1LHY|rcsb pdb:1LI0|rcsb pdb:1LI9|rcsb pdb:1M40|rcsb pdb:1NXY|rcsb pdb:1NY0|rcsb pdb:1NYM|rcsb pdb:1NYY|rcsb pdb:1PZO|rcsb pdb:4QY5|rcsb pdb:4QY6|rcsb pdb:4R4R|rcsb pdb:4R4S|rcsb pdb:1PZP|rcsb pdb:1S0W|rcsb pdb:1TEM|rcsb pdb:1XPB|rcsb pdb:1XXM|rcsb pdb:1YT4|rcsb pdb:1ZG4|rcsb pdb:1ZG6|rcsb pdb:2B5R|rcsb pdb:2V1Z|rcsb pdb:2V20|rcsb pdb:3C7U|rcsb pdb:3C7V|rcsb pdb:3CMZ|rcsb pdb:3DTM|rcsb pdb:3JYI|go:"GO:0046677"(response to antibiotic)|go:"GO:0008800"(beta-lactamase activity)|go:"GO:0030655"(beta-lactam antibiotic catabolic process)|rcsb pdb:3TOI|refseq:WP_063865014.1|rcsb pdb:4GKU|refseq:YP_001096393.1|refseq:YP_006903139.1|refseq:YP_006939984.1|refseq:YP_006940092.1|refseq:YP_006952181.1|refseq:YP_006952421.1|refseq:YP_006952427.1|refseq:YP_006953479.1|refseq:YP_006953762.1|refseq:YP_006953988.1|refseq:YP_006954235.1|rcsb pdb:4IBR|rcsb pdb:4IBX|rcsb pdb:4ZJ2|rcsb pdb:4ZJ3|rcsb pdb:4ZJ1|rcsb pdb:4RVA|rcsb pdb:4RX2|rcsb pdb:4RX3|refseq:WP_000027057.1|refseq:WP_063864949.1|refseq:YP_001816609.1|rcsb pdb:5NPO|rcsb pdb:6B2N|rcsb pdb:5HVI|rcsb pdb:5HW1|rcsb pdb:5HW5|rcsb pdb:5I52|rcsb pdb:5I63|rcsb pdb:5IQ8|rcsb pdb:5KKF|rcsb pdb:5KPU|rcsb pdb:6APA interpro:IPR009099(Beta-lactamase-inhibitor protein BLIP)|interpro:IPR024221|rcsb pdb:1JTG|rcsb pdb:1S0W|rcsb pdb:1XXM|rcsb pdb:2B5R|rcsb pdb:2G2U|rcsb pdb:2G2W|rcsb pdb:3C4O|rcsb pdb:3C4P|rcsb pdb:3C7U|rcsb pdb:3C7V|rcsb pdb:3E2K|rcsb pdb:3E2L|rcsb pdb:3GMU|rcsb pdb:3N4I|go:"GO:0005576"(extracellular region)|go:"GO:0033252"(regulation of beta-lactamase activity)|interpro:IPR037873|refseq:WP_044955856.1 - - - assembly:dimeric, multimeric|3d-r-factors:working 82.700%, free 79.500%|3d-resolution:1.73A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:fDVrtA3cZifFdIZ1xC+teVUEjDs562 rogid:ERIlefx+7eTElVOIVBV3P2UHC+g1901 intact-crc:5499785FA0153C6F|rigid:56zZlFT8iMHdX1lukKAsrlXQTow false sufficient binding region:24-286 sufficient binding region:37-201 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)