#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07306	uniprotkb:Q96G23	intact:EBI-1172335|uniprotkb:I3L1X1|ensembl:ENSP00000269299	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:asgr1_human(display_long)|uniprotkb:ASGR1(gene name)|psi-mi:ASGR1(display_short)|uniprotkb:Hepatic lectin H1(gene name synonym)|uniprotkb:CLEC4H1(gene name synonym)|uniprotkb:C-type lectin domain family 4 member H1(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172345|imex:IM-19013-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001184145.1|refseq:NP_001662.1|ensembl:ENSG00000141505(gene)|ensembl:ENST00000269299(transcript)|go:"GO:0004873"(asialoglycoprotein receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|rcsb pdb:1DV8|rcsb pdb:5JPV|rcsb pdb:5JQ1|rcsb pdb:6YAU|reactome:R-HSA-446203|refseq:XP_011522163.1	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	comment:"The UniprotKB sequence P07306 for the asialoglycoprotein receptor type 1 does not have the initial Met found in the sequence referred to by the authors (GenBank M10058)."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/11/29	2014/10/16	rogid:UH2AMm7waPVhiDZ5WtasFlfRH/o9606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:2FB4F0DCD483BAC9|rigid:79Tl7XMl92WyO4yTU+EWFEps8z8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07307	uniprotkb:Q96G23	intact:EBI-1172636|uniprotkb:O00448|uniprotkb:Q03969|uniprotkb:A6NLV8|uniprotkb:A8MT12|ensembl:ENSP00000347140|uniprotkb:D3DTM9|uniprotkb:D3DTN0	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:asgr2_human(display_long)|uniprotkb:ASGR2(gene name)|psi-mi:ASGR2(display_short)|uniprotkb:Hepatic lectin H2(gene name synonym)|uniprotkb:CLEC4H2(gene name synonym)|uniprotkb:C-type lectin domain family 4 member H2(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172695|imex:IM-19013-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001172.1|refseq:NP_001188281.1|refseq:NP_550434.1|refseq:NP_550435.1|ensembl:ENSG00000161944(gene)|ensembl:ENST00000355035(transcript)|go:"GO:0004873"(asialoglycoprotein receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|reactome:R-HSA-446203|refseq:NP_550436.1|refseq:XP_005256705.1|refseq:XP_006721589.1|refseq:XP_016880140.1|refseq:XP_016880141.1|refseq:XP_016880142.1	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/11/29	2014/10/16	rogid:lE18Bnh/XRccdkXtBadw9N8I0uc9606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:4F996A3B14990B5E|rigid:AqqwIJDUxWEn53fqHcRXFoC1iD4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15245	uniprotkb:Q96G23	intact:EBI-1172714|uniprotkb:A8K1H2|uniprotkb:Q9NQD4|uniprotkb:O15395|ensembl:ENSP00000355930|uniprotkb:A6NFF3|uniprotkb:C9JSU6	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:s22a1_human(display_long)|uniprotkb:SLC22A1(gene name)|psi-mi:SLC22A1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:Organic cation transporter 1(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172729|imex:IM-19013-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003048.1|refseq:NP_694857.1|ensembl:ENSG00000175003(gene)|ensembl:ENST00000366963(transcript)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0008513"(secondary active organic cation transmembrane transporter activity)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0015101"(organic cation transmembrane transporter activity)|go:"GO:0015214"(pyrimidine nucleoside transmembrane transporter activity)|go:"GO:0015651"(quaternary ammonium group transmembrane transporter activity)|go:"GO:0015695"(organic cation transport)|go:"GO:0015697"(quaternary ammonium group transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019534"(toxin transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0048241"(epinephrine transport)|go:"GO:0051610"(serotonin uptake)|go:"GO:0072530"(purine-containing compound transmembrane transport)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901998"(toxin transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-112311|reactome:R-HSA-181430|reactome:R-HSA-2161517|reactome:R-HSA-442660|reactome:R-HSA-549127|refseq:XP_006715615.1	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	caution:The authors state that the 5' ends of the cDNAs for OCT1 began at +917 and +973. Thus the shortest construct begins at amino acid 325. However, they do not specify where the 3' end finishes.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/11/29	2014/10/16	rogid:Y0EKrpDp0Usc166Mn/aJkU84dA49606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:A223AFAD247CA058|rigid:8dW3G3PnCdrEgp51lqXg6Icc3m8	false	sufficient binding region:325-554..554	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P27449	uniprotkb:Q96G23	intact:EBI-721179|uniprotkb:Q6FH26|ensembl:ENSP00000329757	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:vatl_human(display_long)|uniprotkb:ATP6V0C(gene name)|psi-mi:ATP6V0C(display_short)|uniprotkb:ATP6C(gene name synonym)|uniprotkb:ATP6L(gene name synonym)|uniprotkb:ATPL(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172735|imex:IM-19013-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185498.1|refseq:NP_001685.1|ensembl:ENSG00000185883(gene)|ensembl:ENST00000330398(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|mint:P27449|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/11/29	2014/10/16	rogid:SENUYPVXYqkUWD9OawRSREg3SZk9606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:28C5D9DE6F48EE10|rigid:KyeV2nUnKzK5wHxEcqYPX2aBKs8	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07306	uniprotkb:Q96G23	intact:EBI-1172335|uniprotkb:I3L1X1|ensembl:ENSP00000269299	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:asgr1_human(display_long)|uniprotkb:ASGR1(gene name)|psi-mi:ASGR1(display_short)|uniprotkb:Hepatic lectin H1(gene name synonym)|uniprotkb:CLEC4H1(gene name synonym)|uniprotkb:C-type lectin domain family 4 member H1(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172776|imex:IM-19013-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001184145.1|refseq:NP_001662.1|ensembl:ENSG00000141505(gene)|ensembl:ENST00000269299(transcript)|go:"GO:0004873"(asialoglycoprotein receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|rcsb pdb:1DV8|rcsb pdb:5JPV|rcsb pdb:5JQ1|rcsb pdb:6YAU|reactome:R-HSA-446203|refseq:XP_011522163.1	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	comment:"The UniprotKB sequence P07306 for the asialoglycoprotein receptor type 1 does not have the initial Met found in the sequence referred to by the authors (GenBank M10058)."|figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/29	2014/10/16	rogid:UH2AMm7waPVhiDZ5WtasFlfRH/o9606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:29747ACF9F5F7DBD|rigid:79Tl7XMl92WyO4yTU+EWFEps8z8	false	glutathione s tranferase tag:?-?	biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07307	uniprotkb:Q96G23	intact:EBI-1172636|uniprotkb:O00448|uniprotkb:Q03969|uniprotkb:A6NLV8|uniprotkb:A8MT12|ensembl:ENSP00000347140|uniprotkb:D3DTM9|uniprotkb:D3DTN0	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:asgr2_human(display_long)|uniprotkb:ASGR2(gene name)|psi-mi:ASGR2(display_short)|uniprotkb:Hepatic lectin H2(gene name synonym)|uniprotkb:CLEC4H2(gene name synonym)|uniprotkb:C-type lectin domain family 4 member H2(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172835|imex:IM-19013-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001172.1|refseq:NP_001188281.1|refseq:NP_550434.1|refseq:NP_550435.1|ensembl:ENSG00000161944(gene)|ensembl:ENST00000355035(transcript)|go:"GO:0004873"(asialoglycoprotein receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055088"(lipid homeostasis)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|reactome:R-HSA-446203|refseq:NP_550436.1|refseq:XP_005256705.1|refseq:XP_006721589.1|refseq:XP_016880140.1|refseq:XP_016880141.1|refseq:XP_016880142.1	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/29	2014/10/16	rogid:lE18Bnh/XRccdkXtBadw9N8I0uc9606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:3DD1D6D834B8AC3F|rigid:AqqwIJDUxWEn53fqHcRXFoC1iD4	false	glutathione s tranferase tag:?-?	biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96G23	uniprotkb:O15245	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	intact:EBI-1172714|uniprotkb:A8K1H2|uniprotkb:Q9NQD4|uniprotkb:O15395|ensembl:ENSP00000355930|uniprotkb:A6NFF3|uniprotkb:C9JSU6	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:s22a1_human(display_long)|uniprotkb:SLC22A1(gene name)|psi-mi:SLC22A1(display_short)|uniprotkb:OCT1(gene name synonym)|uniprotkb:Organic cation transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172856|imex:IM-19013-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	refseq:NP_003048.1|refseq:NP_694857.1|ensembl:ENSG00000175003(gene)|ensembl:ENST00000366963(transcript)|go:"GO:0005277"(acetylcholine transmembrane transporter activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005330"("dopamine:sodium symporter activity")|go:"GO:0005334"("norepinephrine:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0008504"(monoamine transmembrane transporter activity)|go:"GO:0008513"(secondary active organic cation transmembrane transporter activity)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0015101"(organic cation transmembrane transporter activity)|go:"GO:0015214"(pyrimidine nucleoside transmembrane transporter activity)|go:"GO:0015651"(quaternary ammonium group transmembrane transporter activity)|go:"GO:0015695"(organic cation transport)|go:"GO:0015697"(quaternary ammonium group transport)|go:"GO:0015874"(norepinephrine transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019534"(toxin transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0048241"(epinephrine transport)|go:"GO:0051610"(serotonin uptake)|go:"GO:0072530"(purine-containing compound transmembrane transport)|go:"GO:0090494"(dopamine uptake)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901998"(toxin transport)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR004749(Organic cation transport protein)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-112311|reactome:R-HSA-181430|reactome:R-HSA-2161517|reactome:R-HSA-442660|reactome:R-HSA-549127|refseq:XP_006715615.1	-	-	-	figure legend:4|caution:"It is specified that the hOCT1 construct begins at residue 306 and is the C-terminal half of the protein. However, the authors state that the construct ends at residue 544 and also that it ends at 504. The translation of the GenBank sequence they refer to (U77086)is 554 residues long as the UniprotKB sequence."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/29	2014/10/16	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	rogid:Y0EKrpDp0Usc166Mn/aJkU84dA49606	intact-crc:9CD6FB8820F1D4D3|rigid:8dW3G3PnCdrEgp51lqXg6Icc3m8	false	biotin tag:?-?	glutathione s tranferase tag:?-?|sufficient binding region:306-544..544	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P27449	uniprotkb:Q96G23	intact:EBI-721179|uniprotkb:Q6FH26|ensembl:ENSP00000329757	intact:EBI-1057080|uniprotkb:Q9HD96|uniprotkb:Q9NW79|uniprotkb:D3DV06|uniprotkb:Q5SZE5|ensembl:ENSP00000271688|ensembl:ENSP00000357950	psi-mi:vatl_human(display_long)|uniprotkb:ATP6V0C(gene name)|psi-mi:ATP6V0C(display_short)|uniprotkb:ATP6C(gene name synonym)|uniprotkb:ATP6L(gene name synonym)|uniprotkb:ATPL(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)	psi-mi:cers2_human(display_long)|uniprotkb:CERS2(gene name)|psi-mi:CERS2(display_short)|uniprotkb:TMSG1(gene name synonym)|uniprotkb:Tumor metastasis-suppressor gene 1 protein(gene name synonym)|uniprotkb:SP260(gene name synonym)|uniprotkb:LASS2(gene name synonym)|uniprotkb:LAG1 longevity assurance homolog 2(gene name synonym)|uniprotkb:Sphingosine N-acyltransferase CERS2(gene name synonym)|uniprotkb:Very-long-chain ceramide synthase CERS2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pan et al. (2001)	pubmed:11543633|imex:IM-19013	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1172876|imex:IM-19013-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001185498.1|refseq:NP_001685.1|ensembl:ENSG00000185883(gene)|ensembl:ENST00000330398(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|mint:P27449|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712	refseq:XP_011507754.1|refseq:NP_071358.1|refseq:NP_859530.1|ensembl:ENSG00000143418(gene)|ensembl:ENST00000271688(transcript)|ensembl:ENST00000368954(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050291"(sphingosine N-acyltransferase activity)|go:"GO:1900148"(negative regulation of Schwann cell migration)|interpro:IPR001356(Homeobox)|interpro:IPR006634(TRAM, LAG1 and CLN8 homology)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016439(Longevity assurance, LAG1/LAC1)|mint:Q96G23|reactome:R-HSA-1660661|go:"GO:1905045"(negative regulation of Schwann cell proliferation involved in axon regeneration)	-	-	-	figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/11/29	2014/10/16	rogid:SENUYPVXYqkUWD9OawRSREg3SZk9606	rogid:Eqxvp+41fFXPr+hpqRQsLB6Lq4M9606	intact-crc:EB92A1FD8BEB031B|rigid:KyeV2nUnKzK5wHxEcqYPX2aBKs8	false	glutathione s tranferase tag:?-?	biotin tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)