#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01579	uniprotkb:P15260	intact:EBI-1030767|uniprotkb:Q53ZV4|uniprotkb:B5BU88|ensembl:ENSP00000229135	intact:EBI-1030755|uniprotkb:Q53Y96|uniprotkb:E1P587|ensembl:ENSP00000356713|uniprotkb:B4DFT7	psi-mi:ifng_human(display_long)|uniprotkb:IFNG(gene name)|psi-mi:IFNG(display_short)|uniprotkb:Immune interferon(gene name synonym)	psi-mi:ingr1_human(display_long)|uniprotkb:IFNGR1(gene name)|psi-mi:IFNGR1(display_short)|uniprotkb:CDw119(gene name synonym)|uniprotkb:Interferon gamma receptor alpha-chain(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Randal et al. (2001)	pubmed:11250200	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1030783|rcsb pdb:1FYH	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000610.2|ensembl:ENSG00000111537(gene)|ensembl:ENST00000229135(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032747"(positive regulation of interleukin-23 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032834"(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response)|go:"GO:0033141"(positive regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0040008"(regulation of growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051173"(positive regulation of nitrogen compound metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060550"(positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0060552"(positive regulation of fructose 1,6-bisphosphate metabolic process)|go:"GO:0060557"(positive regulation of vitamin D biosynthetic process)|go:"GO:0060559"(positive regulation of calcidiol 1-monooxygenase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0150076"(neuroinflammatory response)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901857"(positive regulation of cellular respiration)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1904440"(positive regulation of iron ion import across plasma membrane)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000309"("positive regulation of tumor necrosis factor (ligand) superfamily member 11 production")|interpro:IPR002069(Interferon gamma)|interpro:IPR009079(Four-helical cytokine-like, core)|rcsb pdb:1EKU|rcsb pdb:1FG9|rcsb pdb:1FYH|rcsb pdb:1HIG|rcsb pdb:3BES|rcsb pdb:6E3K|rcsb pdb:6E3L|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8877330|reactome:R-HSA-8950505|dip:DIP-483N	refseq:NP_000407.1|ensembl:ENSG00000027697(gene)|ensembl:ENST00000367739(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004906"(interferon-gamma receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019955"(cytokine binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0048143"(astrocyte activation)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008355(Interferon-gamma receptor alpha chain)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR021126|interpro:IPR036116|rcsb pdb:1FG9|rcsb pdb:1FYH|rcsb pdb:1JRH|rcsb pdb:6E3K|rcsb pdb:6E3L|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-9679191|dip:DIP-47N	-	-	-	assembly:dimeric, multimeric|3d-r-factors:working 80.600%, free 75.400%|3d-resolution:2.04A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:TI+IepCwKmdJxLSvLmfLJsj50xg9606	rogid:lE0NJNR3ItPnoiugDg2ZJno2okg9606	intact-crc:AFCF1FC592929025|rigid:IW2olX7QOPj91/XcFz0bs/JjU7I	false	sufficient binding region:1-156	sufficient binding region:18-246	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)