#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0AA04 uniprotkb:P69783 intact:EBI-902853|uniprotkb:P05525|uniprotkb:P07006|ensemblbacteria:AAC75468|ensemblbacteria:BAA16289 intact:EBI-369856|uniprotkb:P08837|uniprotkb:Q47703|ensemblbacteria:AAC75470|ensemblbacteria:BAA16291 psi-mi:pthp_ecoli(display_long)|uniprotkb:ptsH(gene name)|psi-mi:ptsH(display_short)|uniprotkb:hpr(gene name synonym)|uniprotkb:b2415(locus name)|uniprotkb:Histidine-containing protein(gene name synonym)|uniprotkb:JW2408(locus name) psi-mi:ptga_ecoli(display_long)|uniprotkb:crr(gene name)|psi-mi:crr(display_short)|uniprotkb:gsr(gene name synonym)|uniprotkb:iex(gene name synonym)|uniprotkb:tgs(gene name synonym)|uniprotkb:treD(gene name synonym)|uniprotkb:b2417(locus name)|uniprotkb:EIIA-Glc(gene name synonym)|uniprotkb:EIII-Glc(gene name synonym)|uniprotkb:JW2410(locus name)|uniprotkb:Glucose-specific phosphotransferase enzyme IIA component(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Wang et al. (2000) pubmed:11060015|imex:IM-19846 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-903339|rcsb pdb:1ggr|imex:IM-19846-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_000487600.1|refseq:NP_416910.1|dip:DIP-35731N|ensemblbacteria:AAC75468(transcript)|ensemblbacteria:b2415(gene)|ensemblbacteria:BAA16289(gene)|ensemblbacteria:BAA16289(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0045152"(antisigma factor binding)|go:"GO:0045819"(positive regulation of glycogen catabolic process)|interpro:IPR000032(Phosphotransferase system, phosphocarrier HPr protein)|interpro:IPR001020(Phosphotransferase system, HPr histidine phosphorylation site)|interpro:IPR002114(Phosphotransferase system, HPr serine phosphorylation site)|interpro:IPR035895|rcsb pdb:1CM2|rcsb pdb:1CM3|rcsb pdb:1GGR|rcsb pdb:1HDN|rcsb pdb:1J6T|rcsb pdb:1OPD|rcsb pdb:1PFH|rcsb pdb:1POH|rcsb pdb:1VRC|rcsb pdb:2JEL|rcsb pdb:2LRK|rcsb pdb:2LRL|rcsb pdb:2XDF|rcsb pdb:3CCD|rcsb pdb:3EZA|rcsb pdb:3EZB|rcsb pdb:3EZE|rcsb pdb:4XWJ|rcsb pdb:5YA0|rcsb pdb:5YA1|rcsb pdb:5YA2|rcsb pdb:6KCR refseq:NP_416912.1|refseq:WP_000522247.1|ensemblbacteria:AAC75470(transcript)|ensemblbacteria:b2417(gene)|ensemblbacteria:BAA16291(gene)|ensemblbacteria:BAA16291(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0009401"(phosphoenolpyruvate-dependent sugar phosphotransferase system)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0045912"(negative regulation of carbohydrate metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001127(Phosphotransferase system, sugar-specific permease EIIA 1 domain)|interpro:IPR011055(Duplicated hybrid motif)|rcsb pdb:1F3G|rcsb pdb:1F3Z|rcsb pdb:1GGR|rcsb pdb:1GLA|rcsb pdb:1GLB|rcsb pdb:1GLC|rcsb pdb:1GLD|rcsb pdb:1GLE|rcsb pdb:1O2F|rcsb pdb:2F3G|rcsb pdb:2MP0|rcsb pdb:4JBW|dip:DIP-31863N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/14 2014/10/16 rogid:PclWk4uLFrEfcs8pGZ3juGqwvzc83333 rogid:ox+FaNIVP4hJHndITdcRuCbIOZo83333 intact-crc:AED34193DD750210|rigid:rpI9doQG3AW++OZBoQx+LpU3oJg false binding-associated region:70-70|binding-associated region:13-49|binding-associated region:18-18|binding-associated region:18-18|binding-associated region:52-52|binding-associated region:13-13 binding-associated region:39-97|binding-associated region:39-39|binding-associated region:96-96|binding-associated region:99-99|binding-associated region:80-80|binding-associated region:54-54 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)