#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A9P4 uniprotkb:P0AA25 intact:EBI-1029826|uniprotkb:P09625|ensemblbacteria:AAC73974|ensemblbacteria:BAA35613 intact:EBI-368542|uniprotkb:P00274|uniprotkb:P76750|uniprotkb:Q2M889|uniprotkb:Q47674|uniprotkb:Q8XAT2|ensemblbacteria:AAC76786|ensemblbacteria:BAE77517 psi-mi:trxb_ecoli(display_long)|uniprotkb:trxB(gene name)|psi-mi:trxB(display_short)|uniprotkb:b0888(locus name)|uniprotkb:JW0871(locus name) psi-mi:thio_ecoli(display_long)|uniprotkb:trxA(gene name)|psi-mi:trxA(display_short)|uniprotkb:fipA(gene name synonym)|uniprotkb:tsnC(gene name synonym)|uniprotkb:b3781(locus name)|uniprotkb:JW5856(locus name) psi-mi:"MI:0114"(x-ray crystallography) Lennon et al. (2000) pubmed:10947986|imex:IM-27304 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1029844|rcsb pdb:1F6M|imex:IM-27304-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_415408.1|ensemblbacteria:AAC73974(transcript)|ensemblbacteria:b0888(gene)|ensemblbacteria:BAA35613(gene)|ensemblbacteria:BAA35613(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005829"(cytosol)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:1CL0|rcsb pdb:1F6M|rcsb pdb:1TDE|rcsb pdb:1TDF|rcsb pdb:1TRB|refseq:WP_000537418.1|dip:DIP-6168N refseq:WP_001280776.1|refseq:NP_418228.2|ensemblbacteria:AAC76786(transcript)|ensemblbacteria:b3781(gene)|ensemblbacteria:BAE77517(gene)|ensemblbacteria:BAE77517(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016671"(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:1F6M|rcsb pdb:1KEB|rcsb pdb:1M7T|rcsb pdb:1OAZ|rcsb pdb:1SKR|rcsb pdb:1SKS|rcsb pdb:1SKW|rcsb pdb:1SL0|rcsb pdb:1SL1|rcsb pdb:1SL2|rcsb pdb:1SRX|rcsb pdb:1T7P|rcsb pdb:1T8E|rcsb pdb:1THO|rcsb pdb:1TK0|rcsb pdb:1TK5|rcsb pdb:1TK8|rcsb pdb:1TKD|rcsb pdb:1TXX|rcsb pdb:1X9M|rcsb pdb:1X9S|rcsb pdb:1X9W|rcsb pdb:1XOA|rcsb pdb:1XOB|rcsb pdb:1ZCP|rcsb pdb:1ZYQ|rcsb pdb:1ZZY|rcsb pdb:2AJQ|rcsb pdb:2BTO|rcsb pdb:2EIO|rcsb pdb:2EIQ|rcsb pdb:2EIR|rcsb pdb:2FCH|rcsb pdb:2FD3|rcsb pdb:2H6X|rcsb pdb:2H6Y|rcsb pdb:2H6Z|rcsb pdb:2H70|rcsb pdb:2H71|rcsb pdb:2H72|rcsb pdb:2H73|rcsb pdb:2H74|rcsb pdb:2H75|rcsb pdb:2H76|rcsb pdb:2O8V|rcsb pdb:2TIR|rcsb pdb:2TRX|rcsb pdb:3DYR|rcsb pdb:4HU7|rcsb pdb:4HUA|rcsb pdb:4X43|rcsb pdb:5HR0|rcsb pdb:5HR1|rcsb pdb:5HR2|rcsb pdb:5HR3|rcsb pdb:5XOC|rcsb pdb:6GD1|rcsb pdb:6GDG|rcsb pdb:6H7J|rcsb pdb:6H7L|rcsb pdb:6H7M|rcsb pdb:6H7N|rcsb pdb:4HU9|rcsb pdb:6H7O|rcsb pdb:6IBL|rcsb pdb:6LUR|rcsb pdb:6N7W|rcsb pdb:6P7E|rcsb pdb:6Y4Y|rcsb pdb:6Y4Z|rcsb pdb:6YEV|dip:DIP-31856N - - - assembly:octameric, multimeric|3d-r-factors:working 79.500%, free 75.300%|3d-resolution:2.95A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:BZtjd39qKmq1b1wdlDO2+b8rbC483333 rogid:3N6xdnvxqP7urWDcMDIICq+AXMo83333 intact-crc:4370BE0FCD105467|rigid:P+PDBYSBNq64Zpl9kFCDPDrwLTM false sufficient binding region:2-321 sufficient binding region:2-109 4 4 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)