#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9ES39 uniprotkb:P43033 intact:EBI-1007897|ensembl:ENSRNOP00000073786|uniprotkb:Q642F3 intact:EBI-1007886 psi-mi:nde1_rat(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym)|uniprotkb:Nude1(gene name synonym) psi-mi:lis1_bovin(display_long)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:PAFAHA(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kitagawa et al. (2000) pubmed:10940388|imex:IM-18967 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1007885|imex:IM-18967-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620038|refseq:NP_445799.1|ensembl:ENSRNOG00000058007(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|ensembl:ENSRNOT00000086392(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|reactome:R-RNO-5663220|go:"GO:0000776"(kinetochore)|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9648025|go:"GO:0001764"(neuron migration)|refseq:XP_006245911.1|refseq:XP_006245912.1|refseq:XP_006245913.1 interpro:IPR019775|interpro:IPR036322|interpro:IPR037190|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|refseq:NP_777088.1|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like) - - - figure legend:None.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/08 2014/10/16 rogid:CvbIYlBhmBKftmuH0MsqE8rHTnk10116 rogid:LnDrG9jJ0gaGrYGocGR0bVb7OfU9913 intact-crc:6EAA51560C3195B1|rigid:vhKewLbfgPfcMO+vM0jtGWPNIrU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43033 uniprotkb:O35264 intact:EBI-1007886 intact:EBI-915500|ensembl:ENSRNOP00000068672 psi-mi:lis1_bovin(display_long)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:PAFAHA(gene name synonym) psi-mi:pa1b2_rat(display_long)|uniprotkb:PAF acetylhydrolase 30 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit beta(gene name synonym)|uniprotkb:Platelet-activating factor acetylhydrolase alpha 2 subunit(gene name synonym)|uniprotkb:Pafah1b2(gene name)|psi-mi:Pafah1b2(display_short)|uniprotkb:Pafahb(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kitagawa et al. (2000) pubmed:10940388|imex:IM-18967 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1102249|imex:IM-18967-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019775|interpro:IPR036322|interpro:IPR037190|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|refseq:NP_777088.1|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like) rgd:620332|refseq:NP_071782.1|refseq:XP_006243020.1|ensembl:ENSRNOG00000057102(gene)|ensembl:ENSRNOT00000082508(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|reactome:R-RNO-6798695|reactome:R-RNO-6811436 - - - figure legend:None.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2006/09/08 2014/10/16 rogid:LnDrG9jJ0gaGrYGocGR0bVb7OfU9913 rogid:5Y3KS/c8AfWOl2IbXGIHjjVw89g10116 intact-crc:4CA9512FD41C74B1|rigid:9634QHQllSeBUtM8gb+vO5HfO40 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9ES39 uniprotkb:P43033 intact:EBI-1007897|ensembl:ENSRNOP00000073786|uniprotkb:Q642F3 intact:EBI-1007886 psi-mi:nde1_rat(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym)|uniprotkb:Nude1(gene name synonym) psi-mi:lis1_bovin(display_long)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:PAFAHA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitagawa et al. (2000) pubmed:10940388|imex:IM-18967 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1007915|imex:IM-18967-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620038|refseq:NP_445799.1|ensembl:ENSRNOG00000058007(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|ensembl:ENSRNOT00000086392(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|reactome:R-RNO-5663220|go:"GO:0000776"(kinetochore)|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9648025|go:"GO:0001764"(neuron migration)|refseq:XP_006245911.1|refseq:XP_006245912.1|refseq:XP_006245913.1 interpro:IPR019775|interpro:IPR036322|interpro:IPR037190|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|refseq:NP_777088.1|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like) - - - figure legend:Fig. 2, 3A|delivery method:Transfection with Optimem.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/09/08 2014/10/16 rogid:CvbIYlBhmBKftmuH0MsqE8rHTnk10116 rogid:LnDrG9jJ0gaGrYGocGR0bVb7OfU9913 intact-crc:BD3B7BFF842997B2|rigid:vhKewLbfgPfcMO+vM0jtGWPNIrU false myc tag:n-n necessary binding region:2-65|t7 tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:G3HVB8 uniprotkb:Q9ES39 intact:EBI-1007929|ensembl:ENSCGRP00001006672|ensembl:ENSCGRP00015027420 intact:EBI-1007897|ensembl:ENSRNOP00000073786|uniprotkb:Q642F3 psi-mi:g3hvb8_crigr(display_long)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:I79_014899(orf name) psi-mi:nde1_rat(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym)|uniprotkb:Nude1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitagawa et al. (2000) pubmed:10940388|imex:IM-18967 taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1007923|imex:IM-18967-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_003507316.1|refseq:XP_007623063.1|refseq:XP_007623064.1|refseq:XP_007646028.1|ensembl:ENSCGRG00001009049(gene)|ensembl:ENSCGRG00015020798(gene)|ensembl:ENSCGRT00001010519(transcript)|ensembl:ENSCGRT00015033594(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005813"(centrosome)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0009306"(protein secretion)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190 rgd:620038|refseq:NP_445799.1|ensembl:ENSRNOG00000058007(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|ensembl:ENSRNOT00000086392(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|reactome:R-RNO-5663220|go:"GO:0000776"(kinetochore)|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9648025|go:"GO:0001764"(neuron migration)|refseq:XP_006245911.1|refseq:XP_006245912.1|refseq:XP_006245913.1 - - - figure legend:Fig. 2, 4A|inhibition:This interaction is inhibited in the presence of Pafah1b2 and Pafah1b3.|delivery method:Transfection with Optimem.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2006/09/08 2016/01/15 rogid:worzim1DpTldfv3SQdodqPmMozk10029 rogid:CvbIYlBhmBKftmuH0MsqE8rHTnk10116 intact-crc:BAE78B558C414013|rigid:EV4DZt2PnX+622eExkkjvecbLaw false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43033 uniprotkb:O35263 intact:EBI-1007886 intact:EBI-1007944|ensembl:ENSRNOP00000027774 psi-mi:lis1_bovin(display_long)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:PAFAHA(gene name synonym) psi-mi:pa1b3_rat(display_long)|uniprotkb:PAF acetylhydrolase 29 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit gamma(gene name synonym)|uniprotkb:Platelet-activating factor acetylhydrolase alpha 1 subunit(gene name synonym)|uniprotkb:Pafah1b3(gene name)|psi-mi:Pafah1b3(display_short)|uniprotkb:Pafahg(gene name synonym) psi-mi:"MI:0096"(pull down) Kitagawa et al. (2000) pubmed:10940388|imex:IM-18967 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1007943|imex:IM-18967-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019775|interpro:IPR036322|interpro:IPR037190|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|refseq:NP_777088.1|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like) rgd:620333|refseq:NP_446106.1|ensembl:ENSRNOG00000020481(gene)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENSRNOT00000027774(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|reactome:R-RNO-6811436|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0042802"(identical protein binding)|refseq:XP_006228427.1|refseq:XP_017444141.1 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/08 2014/10/16 rogid:LnDrG9jJ0gaGrYGocGR0bVb7OfU9913 rogid:KodvegSs4I7CIz+SlVMOdA/ckaI10116 intact-crc:C63DC72C9BFAB37C|rigid:gVI/SlwpywyZ4LXlgaX4R459USE false necessary binding region:66-410|t7 tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P43033 uniprotkb:O35264 intact:EBI-1007886 intact:EBI-915500|ensembl:ENSRNOP00000068672 psi-mi:lis1_bovin(display_long)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:PAFAHA(gene name synonym) psi-mi:pa1b2_rat(display_long)|uniprotkb:PAF acetylhydrolase 30 kDa subunit(gene name synonym)|uniprotkb:PAF-AH subunit beta(gene name synonym)|uniprotkb:Platelet-activating factor acetylhydrolase alpha 2 subunit(gene name synonym)|uniprotkb:Pafah1b2(gene name)|psi-mi:Pafah1b2(display_short)|uniprotkb:Pafahb(gene name synonym) psi-mi:"MI:0096"(pull down) Kitagawa et al. (2000) pubmed:10940388|imex:IM-18967 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1007957|imex:IM-18967-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019775|interpro:IPR036322|interpro:IPR037190|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|refseq:NP_777088.1|interpro:IPR017252(Dynein regulator)|interpro:IPR020472|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like) rgd:620332|refseq:NP_071782.1|refseq:XP_006243020.1|ensembl:ENSRNOG00000057102(gene)|ensembl:ENSRNOT00000082508(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047179"(platelet-activating factor acetyltransferase activity)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|reactome:R-RNO-6798695|reactome:R-RNO-6811436 - - - figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/08 2014/10/16 rogid:LnDrG9jJ0gaGrYGocGR0bVb7OfU9913 rogid:5Y3KS/c8AfWOl2IbXGIHjjVw89g10116 intact-crc:B0934BB27741B85A|rigid:9634QHQllSeBUtM8gb+vO5HfO40 false necessary binding region:66-410|t7 tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)