#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00763	uniprotkb:P23827	intact:EBI-1029166|ensembl:ENSRNOP00000018853	intact:EBI-1029159|ensemblbacteria:AAC75269|ensemblbacteria:BAA15992	psi-mi:try2_rat(display_long)|uniprotkb:Prss2(gene name)|psi-mi:Prss2(display_short)|uniprotkb:Try2(gene name synonym)|uniprotkb:Anionic trypsin II(gene name synonym)|uniprotkb:Pretrypsinogen II(gene name synonym)|uniprotkb:Serine protease 2(gene name synonym)	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Gillmor et al. (2000)	pubmed:10843853	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1029191|rcsb pdb:1EZS	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:3418|refseq:NP_036861.1|ensembl:ENSRNOG00000032916(gene)|ensembl:ENSRNOT00000018852(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007584"(response to nutrient)|go:"GO:0007586"(digestion)|go:"GO:0030574"(collagen catabolic process)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:1AMH|rcsb pdb:1ANB|rcsb pdb:1ANC|rcsb pdb:1AND|rcsb pdb:1ANE|rcsb pdb:1BRA|rcsb pdb:1BRB|rcsb pdb:1BRC|rcsb pdb:1CO7|rcsb pdb:1DPO|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1F5R|rcsb pdb:1F7Z|rcsb pdb:1FY8|rcsb pdb:1J14|rcsb pdb:1J15|rcsb pdb:1J16|rcsb pdb:1J17|rcsb pdb:1K9O|rcsb pdb:1QL9|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1TRM|rcsb pdb:1YKT|rcsb pdb:1YLC|rcsb pdb:1YLD|rcsb pdb:2TRM|rcsb pdb:3FP6|rcsb pdb:3FP7|rcsb pdb:3FP8|rcsb pdb:3TGI|rcsb pdb:3TGJ|rcsb pdb:3TGK|reactome:R-RNO-1462054|reactome:R-RNO-1592389|reactome:R-RNO-196741|reactome:R-RNO-6798695|reactome:R-RNO-6803157|dip:DIP-6112N	refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|ensemblbacteria:AAC75269(transcript)|ensemblbacteria:b2209(gene)|ensemblbacteria:BAA15992(gene)|ensemblbacteria:BAA15992(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|refseq:WP_000849209.1|interpro:IPR027438|rcsb pdb:4IW4|rcsb pdb:4NIY|interpro:IPR036198|rcsb pdb:7CBK	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 81.200%, free 76.500%|3d-resolution:2.3A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:pd1mQna5A30w4eYG7/ryILU/IFw10116	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	intact-crc:776B268FD989C0F6|rigid:3Stq975SDjdPixXAw9a3UlU/r0Y	false	sufficient binding region:24-246	sufficient binding region:21-162	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23827	uniprotkb:P00763	intact:EBI-1029159|ensemblbacteria:AAC75269|ensemblbacteria:BAA15992	intact:EBI-1029166|ensembl:ENSRNOP00000018853	psi-mi:ecot_ecoli(display_long)|uniprotkb:eco(gene name)|psi-mi:eco(display_short)|uniprotkb:eti(gene name synonym)|uniprotkb:b2209(locus name)|uniprotkb:JW2197(locus name)	psi-mi:try2_rat(display_long)|uniprotkb:Prss2(gene name)|psi-mi:Prss2(display_short)|uniprotkb:Try2(gene name synonym)|uniprotkb:Anionic trypsin II(gene name synonym)|uniprotkb:Pretrypsinogen II(gene name synonym)|uniprotkb:Serine protease 2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Gillmor et al. (2000)	pubmed:10843853	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1029202|rcsb pdb:1EZU	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416713.1|interpro:IPR005658(Proteinase inhibitor I11, ecotin)|interpro:IPR023084|rcsb pdb:1AZZ|rcsb pdb:1ECY|rcsb pdb:1ECZ|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1FI8|rcsb pdb:1ID5|rcsb pdb:1IFG|rcsb pdb:1N8O|rcsb pdb:1P0S|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1XX9|rcsb pdb:1XXD|rcsb pdb:1XXF|ensemblbacteria:AAC75269(transcript)|ensemblbacteria:b2209(gene)|ensemblbacteria:BAA15992(gene)|ensemblbacteria:BAA15992(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|refseq:WP_000849209.1|interpro:IPR027438|rcsb pdb:4IW4|rcsb pdb:4NIY|interpro:IPR036198|rcsb pdb:7CBK	rgd:3418|refseq:NP_036861.1|ensembl:ENSRNOG00000032916(gene)|ensembl:ENSRNOT00000018852(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007584"(response to nutrient)|go:"GO:0007586"(digestion)|go:"GO:0030574"(collagen catabolic process)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:1AMH|rcsb pdb:1ANB|rcsb pdb:1ANC|rcsb pdb:1AND|rcsb pdb:1ANE|rcsb pdb:1BRA|rcsb pdb:1BRB|rcsb pdb:1BRC|rcsb pdb:1CO7|rcsb pdb:1DPO|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1F5R|rcsb pdb:1F7Z|rcsb pdb:1FY8|rcsb pdb:1J14|rcsb pdb:1J15|rcsb pdb:1J16|rcsb pdb:1J17|rcsb pdb:1K9O|rcsb pdb:1QL9|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1TRM|rcsb pdb:1YKT|rcsb pdb:1YLC|rcsb pdb:1YLD|rcsb pdb:2TRM|rcsb pdb:3FP6|rcsb pdb:3FP7|rcsb pdb:3FP8|rcsb pdb:3TGI|rcsb pdb:3TGJ|rcsb pdb:3TGK|reactome:R-RNO-1462054|reactome:R-RNO-1592389|reactome:R-RNO-196741|reactome:R-RNO-6798695|reactome:R-RNO-6803157|dip:DIP-6112N	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 78.200%, free 73.500%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:ZzO2zrHSsO5iH2kANpN5qFp+S8w83333	rogid:pd1mQna5A30w4eYG7/ryILU/IFw10116	intact-crc:D870108FD989CC08|rigid:3Stq975SDjdPixXAw9a3UlU/r0Y	false	sufficient binding region:21-162	sufficient binding region:24-246	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)