#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NRF9	uniprotkb:Q9NR33	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	intact:EBI-867034|uniprotkb:Q53TR2|ensembl:ENSP00000420176	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:dpoe4_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p12(gene name synonym)|uniprotkb:POLE4(gene name)|psi-mi:POLE4(display_short)|uniprotkb:DNA polymerase II subunit 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867043|imex:IM-19401-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	refseq:NP_063949.2|ensembl:ENSG00000115350(gene)|ensembl:ENST00000483063(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	delivery method:Q9NR33; Q9NRF9 transfection|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	rogid:ZtsQxDhQebNPEqYTb+G8yXvXp/49606	intact-crc:66D3C84CEDBF3145|rigid:H+S+zDW6S9ueGyMbCKe0hcAkozI	false	flag tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRF9	uniprotkb:Q9NR33	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	intact:EBI-867034|uniprotkb:Q53TR2|ensembl:ENSP00000420176	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:dpoe4_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p12(gene name synonym)|uniprotkb:POLE4(gene name)|psi-mi:POLE4(display_short)|uniprotkb:DNA polymerase II subunit 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867075|imex:IM-19401-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	refseq:NP_063949.2|ensembl:ENSG00000115350(gene)|ensembl:ENST00000483063(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	delivery method:Q9NR33; Q9NRF9 transfection|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	rogid:ZtsQxDhQebNPEqYTb+G8yXvXp/49606	intact-crc:C93ADFA41F1B9C27|rigid:H+S+zDW6S9ueGyMbCKe0hcAkozI	false	flag tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRF9	uniprotkb:Q9NR33	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	intact:EBI-867034|uniprotkb:Q53TR2|ensembl:ENSP00000420176	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:dpoe4_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p12(gene name synonym)|uniprotkb:POLE4(gene name)|psi-mi:POLE4(display_short)|uniprotkb:DNA polymerase II subunit 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867144|imex:IM-19401-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	refseq:NP_063949.2|ensembl:ENSG00000115350(gene)|ensembl:ENST00000483063(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	delivery method:Q9NR33; Q9NRF9 transfection|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	rogid:ZtsQxDhQebNPEqYTb+G8yXvXp/49606	intact-crc:F376038CB0B279E1|rigid:178KlLLrciRxsg/xg7aXzXYrvow	false	flag tag:?-?	v5 tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRF9	uniprotkb:Q07864	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	intact:EBI-348526|uniprotkb:Q13533|intact:EBI-28987244|ensembl:ENSP00000322570|uniprotkb:Q86VH9	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:dpoe1_human(display_long)|uniprotkb:POLE(gene name)|psi-mi:POLE(display_short)|uniprotkb:POLE1(gene name synonym)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867144|imex:IM-19401-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	refseq:NP_006222.2|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|go:"GO:0008270"(zinc ion binding)|ensembl:ENSG00000177084(gene)|ensembl:ENST00000320574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|ensembl:ENSP00000322570|dip:DIP-24243N	-	-	-	delivery method:Q9NR33; Q9NRF9 transfection|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	rogid:oPDFCAO2AeDB4UjbeBvo8DPi+ow9606	intact-crc:F376038CB0B279E1|rigid:178KlLLrciRxsg/xg7aXzXYrvow	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRF9	uniprotkb:P56282	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	intact:EBI-713847|uniprotkb:A4LBB7|uniprotkb:A6NH58|ensembl:ENSP00000216367|uniprotkb:A0AV55|uniprotkb:O43560|uniprotkb:B4DDE6|uniprotkb:A4FU92	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:dpoe2_human(display_long)|uniprotkb:DNA polymerase epsilon subunit B(gene name synonym)|uniprotkb:POLE2(gene name)|psi-mi:POLE2(display_short)|uniprotkb:DPE2(gene name synonym)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867144|imex:IM-19401-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	ensembl:ENSG00000100479(gene)|ensembl:ENST00000216367(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0016604"(nuclear body)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|interpro:IPR024639|rcsb pdb:2V6Z|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|refseq:NP_001184259.1|refseq:NP_001184260.1|refseq:NP_002683.2|refseq:NP_001335313.1	-	-	-	delivery method:Q9NR33; Q9NRF9 transfection|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	rogid:FjnZTpDQmfJFJ5TTA/7mdbYu8k09606	intact-crc:F376038CB0B279E1|rigid:178KlLLrciRxsg/xg7aXzXYrvow	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P56282	uniprotkb:Q07864	intact:EBI-713847|uniprotkb:A4LBB7|uniprotkb:A6NH58|ensembl:ENSP00000216367|uniprotkb:A0AV55|uniprotkb:O43560|uniprotkb:B4DDE6|uniprotkb:A4FU92	intact:EBI-348526|uniprotkb:Q13533|intact:EBI-28987244|ensembl:ENSP00000322570|uniprotkb:Q86VH9	psi-mi:dpoe2_human(display_long)|uniprotkb:DNA polymerase epsilon subunit B(gene name synonym)|uniprotkb:POLE2(gene name)|psi-mi:POLE2(display_short)|uniprotkb:DPE2(gene name synonym)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:dpoe1_human(display_long)|uniprotkb:POLE(gene name)|psi-mi:POLE(display_short)|uniprotkb:POLE1(gene name synonym)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867115|imex:IM-19401-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100479(gene)|ensembl:ENST00000216367(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0016604"(nuclear body)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|interpro:IPR024639|rcsb pdb:2V6Z|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|refseq:NP_001184259.1|refseq:NP_001184260.1|refseq:NP_002683.2|refseq:NP_001335313.1	refseq:NP_006222.2|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|go:"GO:0008270"(zinc ion binding)|ensembl:ENSG00000177084(gene)|ensembl:ENST00000320574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|ensembl:ENSP00000322570|dip:DIP-24243N	go:"GO:0008622"(epsilon DNA polymerase complex)	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:FjnZTpDQmfJFJ5TTA/7mdbYu8k09606	rogid:oPDFCAO2AeDB4UjbeBvo8DPi+ow9606	intact-crc:05B66DED89E9A744|rigid:178KlLLrciRxsg/xg7aXzXYrvow	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56282	uniprotkb:Q9NRF9	intact:EBI-713847|uniprotkb:A4LBB7|uniprotkb:A6NH58|ensembl:ENSP00000216367|uniprotkb:A0AV55|uniprotkb:O43560|uniprotkb:B4DDE6|uniprotkb:A4FU92	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	psi-mi:dpoe2_human(display_long)|uniprotkb:DNA polymerase epsilon subunit B(gene name synonym)|uniprotkb:POLE2(gene name)|psi-mi:POLE2(display_short)|uniprotkb:DPE2(gene name synonym)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867115|imex:IM-19401-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100479(gene)|ensembl:ENST00000216367(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0016604"(nuclear body)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|interpro:IPR024639|rcsb pdb:2V6Z|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|refseq:NP_001184259.1|refseq:NP_001184260.1|refseq:NP_002683.2|refseq:NP_001335313.1	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	go:"GO:0008622"(epsilon DNA polymerase complex)	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:FjnZTpDQmfJFJ5TTA/7mdbYu8k09606	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	intact-crc:05B66DED89E9A744|rigid:178KlLLrciRxsg/xg7aXzXYrvow	false	-	flag tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56282	uniprotkb:Q9NR33	intact:EBI-713847|uniprotkb:A4LBB7|uniprotkb:A6NH58|ensembl:ENSP00000216367|uniprotkb:A0AV55|uniprotkb:O43560|uniprotkb:B4DDE6|uniprotkb:A4FU92	intact:EBI-867034|uniprotkb:Q53TR2|ensembl:ENSP00000420176	psi-mi:dpoe2_human(display_long)|uniprotkb:DNA polymerase epsilon subunit B(gene name synonym)|uniprotkb:POLE2(gene name)|psi-mi:POLE2(display_short)|uniprotkb:DPE2(gene name synonym)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:dpoe4_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p12(gene name synonym)|uniprotkb:POLE4(gene name)|psi-mi:POLE4(display_short)|uniprotkb:DNA polymerase II subunit 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867115|imex:IM-19401-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100479(gene)|ensembl:ENST00000216367(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0016604"(nuclear body)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|interpro:IPR024639|rcsb pdb:2V6Z|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|refseq:NP_001184259.1|refseq:NP_001184260.1|refseq:NP_002683.2|refseq:NP_001335313.1	refseq:NP_063949.2|ensembl:ENSG00000115350(gene)|ensembl:ENST00000483063(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	go:"GO:0008622"(epsilon DNA polymerase complex)	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:FjnZTpDQmfJFJ5TTA/7mdbYu8k09606	rogid:ZtsQxDhQebNPEqYTb+G8yXvXp/49606	intact-crc:05B66DED89E9A744|rigid:178KlLLrciRxsg/xg7aXzXYrvow	false	-	v5 tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07864	uniprotkb:Q9NRF9	intact:EBI-348526|uniprotkb:Q13533|intact:EBI-28987244|ensembl:ENSP00000322570|uniprotkb:Q86VH9	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	psi-mi:dpoe1_human(display_long)|uniprotkb:POLE(gene name)|psi-mi:POLE(display_short)|uniprotkb:POLE1(gene name synonym)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867125|imex:IM-19401-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006222.2|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|go:"GO:0008270"(zinc ion binding)|ensembl:ENSG00000177084(gene)|ensembl:ENST00000320574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|ensembl:ENSP00000322570|dip:DIP-24243N	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:oPDFCAO2AeDB4UjbeBvo8DPi+ow9606	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	intact-crc:5EBCDE8A3F706203|rigid:MOFUZBUa/VYmGjFZOXIqKaBu6K4	false	-	flag tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q07864	uniprotkb:Q9NR33	intact:EBI-348526|uniprotkb:Q13533|intact:EBI-28987244|ensembl:ENSP00000322570|uniprotkb:Q86VH9	intact:EBI-867034|uniprotkb:Q53TR2|ensembl:ENSP00000420176	psi-mi:dpoe1_human(display_long)|uniprotkb:POLE(gene name)|psi-mi:POLE(display_short)|uniprotkb:POLE1(gene name synonym)|uniprotkb:DNA polymerase II subunit A(gene name synonym)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)	psi-mi:dpoe4_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p12(gene name synonym)|uniprotkb:POLE4(gene name)|psi-mi:POLE4(display_short)|uniprotkb:DNA polymerase II subunit 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867125|imex:IM-19401-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006222.2|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0048568"(embryonic organ development)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|go:"GO:0008270"(zinc ion binding)|ensembl:ENSG00000177084(gene)|ensembl:ENST00000320574(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|ensembl:ENSP00000322570|dip:DIP-24243N	refseq:NP_063949.2|ensembl:ENSG00000115350(gene)|ensembl:ENST00000483063(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:oPDFCAO2AeDB4UjbeBvo8DPi+ow9606	rogid:ZtsQxDhQebNPEqYTb+G8yXvXp/49606	intact-crc:5EBCDE8A3F706203|rigid:MOFUZBUa/VYmGjFZOXIqKaBu6K4	false	-	v5 tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56282	uniprotkb:Q9NRF9	intact:EBI-713847|uniprotkb:A4LBB7|uniprotkb:A6NH58|ensembl:ENSP00000216367|uniprotkb:A0AV55|uniprotkb:O43560|uniprotkb:B4DDE6|uniprotkb:A4FU92	intact:EBI-744901|uniprotkb:Q5W0U1|uniprotkb:Q8N758|uniprotkb:Q8NCE5|uniprotkb:Q9NR32|ensembl:ENSP00000363284|ensembl:ENSP00000363286	psi-mi:dpoe2_human(display_long)|uniprotkb:DNA polymerase epsilon subunit B(gene name synonym)|uniprotkb:POLE2(gene name)|psi-mi:POLE2(display_short)|uniprotkb:DPE2(gene name synonym)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:dpoe3_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p17(gene name synonym)|uniprotkb:Chromatin accessibility complex 17 kDa protein(gene name synonym)|uniprotkb:Arsenic-transactivated protein(gene name synonym)|uniprotkb:POLE3(gene name)|psi-mi:POLE3(display_short)|uniprotkb:CHRAC17(gene name synonym)|uniprotkb:DNA polymerase II subunit 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867134|imex:IM-19401-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100479(gene)|ensembl:ENST00000216367(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0016604"(nuclear body)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|interpro:IPR024639|rcsb pdb:2V6Z|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|refseq:NP_001184259.1|refseq:NP_001184260.1|refseq:NP_002683.2|refseq:NP_001335313.1	refseq:NP_001265184.1|refseq:NP_059139.3|ensembl:ENSG00000148229(gene)|ensembl:ENST00000374169(transcript)|ensembl:ENST00000374171(transcript)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0008623"(CHRAC)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:FjnZTpDQmfJFJ5TTA/7mdbYu8k09606	rogid:eTI1XsrypxKqml09tm4GAImoZgI9606	intact-crc:80323A3BDCED524C|rigid:MMGFLiwHQtv5R3ApkNKIQGItY3M	false	-	flag tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56282	uniprotkb:Q9NR33	intact:EBI-713847|uniprotkb:A4LBB7|uniprotkb:A6NH58|ensembl:ENSP00000216367|uniprotkb:A0AV55|uniprotkb:O43560|uniprotkb:B4DDE6|uniprotkb:A4FU92	intact:EBI-867034|uniprotkb:Q53TR2|ensembl:ENSP00000420176	psi-mi:dpoe2_human(display_long)|uniprotkb:DNA polymerase epsilon subunit B(gene name synonym)|uniprotkb:POLE2(gene name)|psi-mi:POLE2(display_short)|uniprotkb:DPE2(gene name synonym)|uniprotkb:DNA polymerase II subunit 2(gene name synonym)	psi-mi:dpoe4_human(display_long)|uniprotkb:DNA polymerase epsilon subunit p12(gene name synonym)|uniprotkb:POLE4(gene name)|psi-mi:POLE4(display_short)|uniprotkb:DNA polymerase II subunit 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Li et al. (2000)	pubmed:10801849|imex:IM-19401	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-867134|imex:IM-19401-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100479(gene)|ensembl:ENST00000216367(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0016604"(nuclear body)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR016266(DNA polymerase epsilon, subunit B)|interpro:IPR024639|rcsb pdb:2V6Z|rcsb pdb:5VBN|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962|refseq:NP_001184259.1|refseq:NP_001184260.1|refseq:NP_002683.2|refseq:NP_001335313.1	refseq:NP_063949.2|ensembl:ENSG00000115350(gene)|ensembl:ENST00000483063(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110314|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-68952|reactome:R-HSA-68962	-	-	-	dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2006/02/27	2014/10/16	rogid:FjnZTpDQmfJFJ5TTA/7mdbYu8k09606	rogid:ZtsQxDhQebNPEqYTb+G8yXvXp/49606	intact-crc:80323A3BDCED524C|rigid:MMGFLiwHQtv5R3ApkNKIQGItY3M	false	-	v5 tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)