#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P28339 uniprotkb:P49004 intact:EBI-863873 intact:EBI-863868|uniprotkb:Q29RZ3|ensembl:ENSBTAP00000016237 psi-mi:dpod1_bovin(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short) psi-mi:dpod2_bovin(display_long)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)|uniprotkb:POLD2(gene name)|psi-mi:POLD2(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Liu et al. (2000) pubmed:10751307 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863883 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776852.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process) refseq:NP_776853.2|refseq:XP_015325451.1|refseq:XP_015325452.1|ensembl:ENSBTAG00000012241(gene)|ensembl:ENSBTAT00000016237(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863 go:"GO:0003891"|go:"GO:0005659" - - comment:Mass spec also identified Keratin 16 - this has been assumed to be a contaminant. taxid:9913(bovin-thymus)|taxid:9913(Bovine thymus) - 2006/02/21 2014/10/16 rogid:hhfVc1Mvp3FO4XxtVUtKnAMoib09913 rogid:TQLo/x0FzDPbKr4Z+3Ex5btG7Ms9913 intact-crc:967C83AB8667EABE|rigid:pJrnwOK26p39y4bqTmrX3JR/DwA false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P28339 uniprotkb:P84798 intact:EBI-863873 intact:EBI-863888|ensembl:ENSBTAP00000042403 psi-mi:dpod1_bovin(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short) psi-mi:dpod3_bovin(display_long)|uniprotkb:DNA polymerase delta subunit p66(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:POLD3(gene name)|psi-mi:POLD3(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Liu et al. (2000) pubmed:10751307 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863883 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776852.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process) ensembl:ENSBTAG00000016869(gene)|ensembl:ENSBTAT00000044966(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|interpro:IPR019038|interpro:IPR041913 go:"GO:0003891"|go:"GO:0005659" - - comment:Mass spec also identified Keratin 16 - this has been assumed to be a contaminant. taxid:9913(bovin-thymus)|taxid:9913(Bovine thymus) - 2006/02/21 2014/10/16 rogid:hhfVc1Mvp3FO4XxtVUtKnAMoib09913 rogid:Xz/3oIIahQX+3whpAzDjAQ6tRxY9913 intact-crc:967C83AB8667EABE|rigid:pJrnwOK26p39y4bqTmrX3JR/DwA false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P28339 uniprotkb:Q3T0X9 intact:EBI-863873 intact:EBI-863892 psi-mi:dpod1_bovin(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short) psi-mi:dpod4_bovin(display_long)|uniprotkb:DNA polymerase delta subunit p12(gene name synonym)|uniprotkb:POLD4(gene name)|psi-mi:POLD4(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Liu et al. (2000) pubmed:10751307 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863883 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776852.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process) interpro:IPR007218(DNA polymerase delta, subunit 4)|refseq:NP_001069949.1|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process) go:"GO:0003891"|go:"GO:0005659" - - comment:Mass spec also identified Keratin 16 - this has been assumed to be a contaminant. taxid:9913(bovin-thymus)|taxid:9913(Bovine thymus) - 2006/02/21 2014/10/16 rogid:hhfVc1Mvp3FO4XxtVUtKnAMoib09913 rogid:3ci0iAk2q+mPgSMcv9cSJ6apM6g9913 intact-crc:967C83AB8667EABE|rigid:pJrnwOK26p39y4bqTmrX3JR/DwA false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P28339 uniprotkb:P49004 intact:EBI-863873 intact:EBI-863868|uniprotkb:Q29RZ3|ensembl:ENSBTAP00000016237 psi-mi:dpod1_bovin(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short) psi-mi:dpod2_bovin(display_long)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)|uniprotkb:POLD2(gene name)|psi-mi:POLD2(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Liu et al. (2000) pubmed:10751307 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863906 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776852.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process) refseq:NP_776853.2|refseq:XP_015325451.1|refseq:XP_015325452.1|ensembl:ENSBTAG00000012241(gene)|ensembl:ENSBTAT00000016237(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863 go:"GO:0003891"|go:"GO:0005659" - - - taxid:9913(bovin-thymus)|taxid:9913(Bovine thymus) - 2006/02/21 2014/10/16 rogid:hhfVc1Mvp3FO4XxtVUtKnAMoib09913 rogid:TQLo/x0FzDPbKr4Z+3Ex5btG7Ms9913 intact-crc:1E514F3EE4143BAC|rigid:pJrnwOK26p39y4bqTmrX3JR/DwA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28339 uniprotkb:P84798 intact:EBI-863873 intact:EBI-863888|ensembl:ENSBTAP00000042403 psi-mi:dpod1_bovin(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short) psi-mi:dpod3_bovin(display_long)|uniprotkb:DNA polymerase delta subunit p66(gene name synonym)|uniprotkb:p68(gene name synonym)|uniprotkb:POLD3(gene name)|psi-mi:POLD3(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Liu et al. (2000) pubmed:10751307 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863906 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776852.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process) ensembl:ENSBTAG00000016869(gene)|ensembl:ENSBTAT00000044966(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1904161"(DNA synthesis involved in UV-damage excision repair)|interpro:IPR019038|interpro:IPR041913 go:"GO:0003891"|go:"GO:0005659" - - - taxid:9913(bovin-thymus)|taxid:9913(Bovine thymus) - 2006/02/21 2014/10/16 rogid:hhfVc1Mvp3FO4XxtVUtKnAMoib09913 rogid:Xz/3oIIahQX+3whpAzDjAQ6tRxY9913 intact-crc:1E514F3EE4143BAC|rigid:pJrnwOK26p39y4bqTmrX3JR/DwA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P28339 uniprotkb:Q3T0X9 intact:EBI-863873 intact:EBI-863892 psi-mi:dpod1_bovin(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short) psi-mi:dpod4_bovin(display_long)|uniprotkb:DNA polymerase delta subunit p12(gene name synonym)|uniprotkb:POLD4(gene name)|psi-mi:POLD4(display_short) psi-mi:"MI:0226"(ion exchange chromatography) Liu et al. (2000) pubmed:10751307 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-863906 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776852.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR023211|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process) interpro:IPR007218(DNA polymerase delta, subunit 4)|refseq:NP_001069949.1|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process) go:"GO:0003891"|go:"GO:0005659" - - - taxid:9913(bovin-thymus)|taxid:9913(Bovine thymus) - 2006/02/21 2014/10/16 rogid:hhfVc1Mvp3FO4XxtVUtKnAMoib09913 rogid:3ci0iAk2q+mPgSMcv9cSJ6apM6g9913 intact-crc:1E514F3EE4143BAC|rigid:pJrnwOK26p39y4bqTmrX3JR/DwA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)