#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18851	uniprotkb:Q04004	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	intact:EBI-22158|uniprotkb:D6VSG7|ensemblfungi:YDR183W	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:plp1_yeast(display_long)|uniprotkb:YD9395.17(orf name)|uniprotkb:YDR183W(locus name)|uniprotkb:PLP1(gene name)|psi-mi:PLP1(display_short)	psi-mi:"MI:0096"(pull down)	Flanary et al. (2000)	pubmed:10749875|imex:IM-19653	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-978275|imex:IM-19653-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	refseq:NP_010469.3|sgd:S000002591|dip:DIP-1793N|ensemblfungi:YDR183W(gene)|ensemblfungi:YDR183W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007329"(positive regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|interpro:IPR036249|interpro:IPR024253	go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)	crc64:4B0E26040AAA83E5	-	figure legend:3|comment:The interaction is enhanced by pretreating the cells with alpha-factor, as well by lysing the cells in presence of GTPgammaS.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/27	2014/10/16	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rogid:zzWwXlCu5/6+gjVx9NDfdkNzh/E559292	intact-crc:A7C0F25DFF17F8CD|rigid:sGAw7RYFyZ7dRicZgjWlYY6At/8	false	-	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18851	uniprotkb:Q12017	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	intact:EBI-39032|uniprotkb:D6W2Y0|ensemblfungi:YOR281C	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:plp2_yeast(display_long)|uniprotkb:Viral IAP-associated factor 1 homolog(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:VIAF1(gene name synonym)|uniprotkb:YOR281C(locus name)	psi-mi:"MI:0096"(pull down)	Flanary et al. (2000)	pubmed:10749875|imex:IM-19653	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-978283|imex:IM-19653-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	sgd:S000005807|refseq:NP_014924.3|dip:DIP-5004N|ensemblfungi:YOR281C(gene)|ensemblfungi:YOR281C_mRNA(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007329"(positive regulation of transcription from RNA polymerase II promoter by pheromones)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1903645"(negative regulation of chaperone-mediated protein folding)|interpro:IPR036249	go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)	crc64:4B0E26040AAA83E5	crc64:414A696FFBDBD833	figure legend:3|comment:The interaction is very weak, but stated as evident.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/27	2014/10/16	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	rogid:WOaWn+K/BvACkG9vkityk45XhMQ559292	intact-crc:0C5DD9FD1CA92408|rigid:/lt6YQSiWl708FlrnOlDxxptmCo	false	-	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08539	uniprotkb:P18851	intact:EBI-7376|uniprotkb:D3DKU8|ensemblfungi:YHR005C	intact:EBI-7390|uniprotkb:D6W2R8|ensemblfungi:YOR212W	psi-mi:gpa1_yeast(display_long)|uniprotkb:YHR005C(locus name)|uniprotkb:GPA1(gene name)|psi-mi:GPA1(display_short)|uniprotkb:CDC70(gene name synonym)|uniprotkb:DAC1(gene name synonym)|uniprotkb:SCG1(gene name synonym)|uniprotkb:GP1-alpha(gene name synonym)	psi-mi:gbb_yeast(display_long)|uniprotkb:YOR50-2(orf name)|uniprotkb:YOR212W(locus name)|uniprotkb:STE4(gene name)|psi-mi:STE4(display_short)	psi-mi:"MI:0096"(pull down)	Flanary et al. (2000)	pubmed:10749875|imex:IM-19653	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-978292|imex:IM-19653-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011868.1|sgd:S000001047|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-416482|dip:DIP-15N|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148|ensemblfungi:YHR005C(gene)|ensemblfungi:YHR005C_mRNA(transcript)|go:"GO:0000742"(karyogamy involved in conjugation with cellular fusion)|go:"GO:0000743"(nuclear migration involved in conjugation with cellular fusion)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000754"(adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048017"(inositol lipid-mediated signaling)|go:"GO:0071701"(regulation of MAPK export from nucleus)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:1SCG|rcsb pdb:7AD3	sgd:S000005738|refseq:NP_014855.3|mint:P18851|dip:DIP-954N|ensemblfungi:YOR212W(gene)|ensemblfungi:YOR212W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005937"(mating projection)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010525"(regulation of transposition, RNA-mediated)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0043577"(chemotropism)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0120171"(Cdc24p-Far1p-Gbetagamma complex)|go:"GO:1903260"(protein localization to mating projection tip)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:1SCG|reactome:R-SCE-6814122	go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)	crc64:2E87C546E133D6E5	crc64:4B0E26040AAA83E5	figure legend:3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/07/27	2014/10/16	rogid:SxuqaRpicb7ZBsQju2vD6C8h3X4559292	rogid:nDgadSWQPcmSvQlIEjpNHPl3Hjc559292	intact-crc:9BE3158D90993155|rigid:qZT9XuLaPi6PXvNRlzA0mIUc71A	false	glutathione s tranferase tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)