#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P52594	uniprotkb:P42566	intact:EBI-996560|uniprotkb:Q15277|uniprotkb:Q4VAS0|uniprotkb:Q4VAS1|uniprotkb:Q4VAS3|uniprotkb:Q53QT8|uniprotkb:Q53R11|uniprotkb:B3KUL1|uniprotkb:E9PHX7|ensembl:ENSP00000312059	intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798	psi-mi:agfg1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein(gene name synonym)|uniprotkb:Rev-interacting protein(gene name synonym)|uniprotkb:Rev/Rex activation domain-binding protein(gene name synonym)|uniprotkb:AGFG1(gene name)|psi-mi:AGFG1(display_short)|uniprotkb:RAB(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:HRB(gene name synonym)|uniprotkb:Nucleoporin-like protein RIP(gene name synonym)	psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Doria et al. (1999)	pubmed:10613896|imex:IM-19669	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-996590|imex:IM-19669-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128660.1|refseq:NP_001128661.1|refseq:NP_004495.2|ensembl:ENSP00000312059|ensembl:ENST00000373671|ensembl:ENSP00000362775|ensembl:ENST00000409171|ensembl:ENSP00000387218|ensembl:ENST00000409979|ensembl:ENSP00000387282|refseq:NP_001128659.1|go:"GO:0005643"(nuclear pore)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:2D9L|rcsb pdb:2OLM|rcsb pdb:2VX8|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000173744(gene)|ensembl:ENST00000310078(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|dip:DIP-35546N	refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N	-	-	-	figure legend:3a|comment:"Interactions appears to be required for HIV-1 Rev protein activation (measured by CAT assay)."|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-c33a)|taxid:9606(Homo sapiens epihelial cervix carcinoma cells)	-	2006/08/23	2014/10/16	rogid:dmA7pBiLW9jnoJellR8WQP1zD6g9606	rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606	intact-crc:8541229B5F35BCBD|rigid:4focRK4iG6wLFJuOuOqggsA1C+s	false	ha tag:?-?|mutation disrupting interaction:436-436,542-542,561-561,451-451	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)