#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P18314 uniprotkb:P18315 intact:EBI-1028571 intact:EBI-1028587 psi-mi:ure1_kleae(display_long)|uniprotkb:ureC(gene name)|psi-mi:ureC(display_short)|uniprotkb:Urea amidohydrolase subunit alpha(gene name synonym) psi-mi:ure2_kleae(display_long)|uniprotkb:ureB(gene name)|psi-mi:ureB(display_short)|uniprotkb:Urea amidohydrolase subunit beta(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yamaguchi et al. (1999) pubmed:10555581 taxid:548(entae)|taxid:548(Enterobacter aerogenes) taxid:548(entae)|taxid:548(Enterobacter aerogenes) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1028599|rcsb pdb:1EF2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011612(Urease alpha-subunit, N-terminal)|interpro:IPR005848(Urease, alpha subunit)|interpro:IPR017951|interpro:IPR017950|rcsb pdb:1A5K|rcsb pdb:1A5L|rcsb pdb:1A5M|rcsb pdb:1A5N|rcsb pdb:1A5O|rcsb pdb:1EF2|rcsb pdb:1EJR|rcsb pdb:1EJS|rcsb pdb:1EJT|rcsb pdb:1EJU|rcsb pdb:1EJV|rcsb pdb:1EJW|rcsb pdb:1EJX|rcsb pdb:1FWA|rcsb pdb:1FWB|rcsb pdb:1FWC|rcsb pdb:1FWD|rcsb pdb:1FWE|rcsb pdb:1FWF|rcsb pdb:1FWG|rcsb pdb:1FWH|rcsb pdb:1FWI|rcsb pdb:1FWJ|rcsb pdb:1KRA|rcsb pdb:1KRB|rcsb pdb:1KRC|rcsb pdb:2KAU|go:"GO:0005737"(cytoplasm)|go:"GO:0009039"(urease activity)|go:"GO:0016151"(nickel cation binding)|go:"GO:0043419"(urea catabolic process)|interpro:IPR032466|rcsb pdb:4EP8|rcsb pdb:4EPB|rcsb pdb:4EPD|rcsb pdb:4EPE|interpro:IPR029754 interpro:IPR002019(Urease, beta subunit)|rcsb pdb:1A5K|rcsb pdb:1A5L|rcsb pdb:1A5M|rcsb pdb:1A5N|rcsb pdb:1A5O|rcsb pdb:1EF2|rcsb pdb:1EJR|rcsb pdb:1EJS|rcsb pdb:1EJV|rcsb pdb:1EJW|rcsb pdb:1EJX|rcsb pdb:1FWA|rcsb pdb:1FWB|rcsb pdb:1FWC|rcsb pdb:1FWD|rcsb pdb:1FWE|rcsb pdb:1FWF|rcsb pdb:1FWG|rcsb pdb:1FWH|rcsb pdb:1FWI|rcsb pdb:1EJT|rcsb pdb:1EJU|rcsb pdb:1FWJ|rcsb pdb:1KRA|rcsb pdb:1KRB|rcsb pdb:1KRC|rcsb pdb:2KAU|go:"GO:0009039"(urease activity)|go:"GO:0035550"(urease complex)|go:"GO:0043419"(urea catabolic process)|rcsb pdb:4EP8|rcsb pdb:4EPB|rcsb pdb:4EPD|rcsb pdb:4EPE|interpro:IPR036461|refseq:WP_002916872.1 - - - assembly:nonameric, multimeric|3d-r-factors:working 82.800%|3d-resolution:2.5A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:ubPFdBN6TPZo8Ks7ixT79pErsF4548 rogid:YTzOIZbmBtufanj1ws2u/+9gfH8548 intact-crc:AEC23F57F94C7C1F|rigid:joxYvcATqfHs3AMDRhm0dteIdXg false sufficient binding region:2-567 sufficient binding region:1-101 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18314 uniprotkb:P18316 intact:EBI-1028571 intact:EBI-1028581 psi-mi:ure1_kleae(display_long)|uniprotkb:ureC(gene name)|psi-mi:ureC(display_short)|uniprotkb:Urea amidohydrolase subunit alpha(gene name synonym) psi-mi:ure3_kleae(display_long)|uniprotkb:ureA(gene name)|psi-mi:ureA(display_short)|uniprotkb:Urea amidohydrolase subunit gamma(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yamaguchi et al. (1999) pubmed:10555581 taxid:548(entae)|taxid:548(Enterobacter aerogenes) taxid:548(entae)|taxid:548(Enterobacter aerogenes) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1028599|rcsb pdb:1EF2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011612(Urease alpha-subunit, N-terminal)|interpro:IPR005848(Urease, alpha subunit)|interpro:IPR017951|interpro:IPR017950|rcsb pdb:1A5K|rcsb pdb:1A5L|rcsb pdb:1A5M|rcsb pdb:1A5N|rcsb pdb:1A5O|rcsb pdb:1EF2|rcsb pdb:1EJR|rcsb pdb:1EJS|rcsb pdb:1EJT|rcsb pdb:1EJU|rcsb pdb:1EJV|rcsb pdb:1EJW|rcsb pdb:1EJX|rcsb pdb:1FWA|rcsb pdb:1FWB|rcsb pdb:1FWC|rcsb pdb:1FWD|rcsb pdb:1FWE|rcsb pdb:1FWF|rcsb pdb:1FWG|rcsb pdb:1FWH|rcsb pdb:1FWI|rcsb pdb:1FWJ|rcsb pdb:1KRA|rcsb pdb:1KRB|rcsb pdb:1KRC|rcsb pdb:2KAU|go:"GO:0005737"(cytoplasm)|go:"GO:0009039"(urease activity)|go:"GO:0016151"(nickel cation binding)|go:"GO:0043419"(urea catabolic process)|interpro:IPR032466|rcsb pdb:4EP8|rcsb pdb:4EPB|rcsb pdb:4EPD|rcsb pdb:4EPE|interpro:IPR029754 interpro:IPR002026(Urease, gamma subunit region)|interpro:IPR012010(Urease, gamma subunit)|rcsb pdb:1A5K|rcsb pdb:1A5L|rcsb pdb:1A5M|rcsb pdb:1A5N|rcsb pdb:1A5O|rcsb pdb:1EF2|rcsb pdb:1EJR|rcsb pdb:1EJS|rcsb pdb:1EJT|rcsb pdb:1EJU|rcsb pdb:1EJV|rcsb pdb:1EJW|rcsb pdb:1EJX|rcsb pdb:1FWA|rcsb pdb:1FWB|rcsb pdb:1FWC|rcsb pdb:1FWD|rcsb pdb:1FWE|rcsb pdb:1FWF|rcsb pdb:1FWG|rcsb pdb:1FWH|rcsb pdb:1FWI|rcsb pdb:1FWJ|rcsb pdb:1KRA|rcsb pdb:1KRB|rcsb pdb:1KRC|rcsb pdb:2KAU|go:"GO:0005737"(cytoplasm)|go:"GO:0009039"(urease activity)|go:"GO:0016151"(nickel cation binding)|go:"GO:0043419"(urea catabolic process)|rcsb pdb:4EP8|rcsb pdb:4EPB|rcsb pdb:4EPD|rcsb pdb:4EPE|interpro:IPR036463|refseq:WP_002916871.1 - - - assembly:nonameric, multimeric|3d-r-factors:working 82.800%|3d-resolution:2.5A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/09/20 2014/10/16 rogid:ubPFdBN6TPZo8Ks7ixT79pErsF4548 rogid:MQNvfQD2AwW3pn1szhEv2aGPJJk548 intact-crc:AEC23F57F94C7C1F|rigid:joxYvcATqfHs3AMDRhm0dteIdXg false sufficient binding region:2-567 sufficient binding region:1-100 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)