#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P20664	uniprotkb:P33610	intact:EBI-848742|ensembl:ENSMUSP00000026461	intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848753|imex:IM-20077-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding)	go:"GO:0000060"(obsolete protein import into nucleus, translocation)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090	intact-crc:9EB58CC32BA52429|rigid:tIafYqZm/Mr+nL/PUhTel2qjP0s	false	ha tag:n-n	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33611	uniprotkb:P33609	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-688051|ensembl:ENSMUSP00000006856	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848764|imex:IM-20077-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0000060"(obsolete protein import into nucleus, translocation)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	intact-crc:BE6F6BAF71C1E260|rigid:kuzXqDb8b07xQjxMdPptQTYsEKs	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33611	uniprotkb:P33609	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-688051|ensembl:ENSMUSP00000006856	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848769|imex:IM-20077-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0000060"(obsolete protein import into nucleus, translocation)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	intact-crc:EC8A45890C80D0D6|rigid:UGHFm5iBSUKqmI2cRa9cQO3H/Ns	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33611	uniprotkb:P33610	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848769|imex:IM-20077-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding)	go:"GO:0000060"(obsolete protein import into nucleus, translocation)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090	intact-crc:EC8A45890C80D0D6|rigid:UGHFm5iBSUKqmI2cRa9cQO3H/Ns	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33611	uniprotkb:P33609	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-688051|ensembl:ENSMUSP00000006856	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848775|imex:IM-20077-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0000060"(obsolete protein import into nucleus, translocation)|go:"GO:0005658"("alpha DNA polymerase:primase complex")	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	intact-crc:21956610D0F52984|rigid:ttw1t4uLY6fT7Okd7zdP7HuisBk	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33611	uniprotkb:P20664	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-848742|ensembl:ENSMUSP00000026461	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848775|imex:IM-20077-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0000060"(obsolete protein import into nucleus, translocation)|go:"GO:0005658"("alpha DNA polymerase:primase complex")	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	intact-crc:21956610D0F52984|rigid:ttw1t4uLY6fT7Okd7zdP7HuisBk	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33611	uniprotkb:P33610	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848775|imex:IM-20077-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding)	go:"GO:0000060"(obsolete protein import into nucleus, translocation)|go:"GO:0005658"("alpha DNA polymerase:primase complex")	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090	intact-crc:21956610D0F52984|rigid:ttw1t4uLY6fT7Okd7zdP7HuisBk	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33609	uniprotkb:P20664	intact:EBI-688051|ensembl:ENSMUSP00000006856	intact:EBI-848742|ensembl:ENSMUSP00000026461	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848828|imex:IM-20077-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0005737"(cytoplasm)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	intact-crc:7D05959F45EA7E14|rigid:cGNLbQYewR8kK/UVc9UXW+JO3C4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33609	uniprotkb:P33610	intact:EBI-688051|ensembl:ENSMUSP00000006856	intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848828|imex:IM-20077-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding)	go:"GO:0005737"(cytoplasm)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090	intact-crc:7D05959F45EA7E14|rigid:cGNLbQYewR8kK/UVc9UXW+JO3C4	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33609	uniprotkb:P20664	intact:EBI-688051|ensembl:ENSMUSP00000006856	intact:EBI-848742|ensembl:ENSMUSP00000026461	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848834|imex:IM-20077-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0005737"(cytoplasm)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	intact-crc:27436CEB5BDB7038|rigid:cGNLbQYewR8kK/UVc9UXW+JO3C4	false	necessary binding region:1279-1465|his tag:n-n	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P33609	uniprotkb:P33610	intact:EBI-688051|ensembl:ENSMUSP00000006856	intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848834|imex:IM-20077-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding)	go:"GO:0005737"(cytoplasm)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090	intact-crc:27436CEB5BDB7038|rigid:cGNLbQYewR8kK/UVc9UXW+JO3C4	false	necessary binding region:1279-1465|his tag:n-n	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)
uniprotkb:P20664	uniprotkb:P33609	intact:EBI-848742|ensembl:ENSMUSP00000026461	intact:EBI-688051|ensembl:ENSMUSP00000006856	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848860|imex:IM-20077-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	intact-crc:D09382969CED2B45|rigid:n+aKK+YGbXnzall9OTmmOMy1998	false	-	necessary binding region:1279-1465|his tag:n-n	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P20664	uniprotkb:P33611	intact:EBI-848742|ensembl:ENSMUSP00000026461	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848931|imex:IM-20077-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	-	-	-	comment:P33610 co-expressed in this experiment|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	intact-crc:A04A683DE3D89BEA|rigid:NeyB19tR3MnYOnPDc7/AcYRGfPs	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P20664	uniprotkb:P33609	intact:EBI-848742|ensembl:ENSMUSP00000026461	intact:EBI-688051|ensembl:ENSMUSP00000006856	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848931|imex:IM-20077-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	-	-	-	comment:P33610 co-expressed in this experiment|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	intact-crc:A04A683DE3D89BEA|rigid:NeyB19tR3MnYOnPDc7/AcYRGfPs	false	-	sufficient binding region:1235-1465	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P33609	uniprotkb:P33611	intact:EBI-688051|ensembl:ENSMUSP00000006856	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:"MI:0096"(pull down)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848912|imex:IM-20077-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2006/02/07	2014/10/16	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	intact-crc:415521CC20685409|rigid:kuzXqDb8b07xQjxMdPptQTYsEKs	false	his tag:n-n|necessary binding region:1279-1465|mutation decreasing interaction:1287-1287,1290-1290|mutation decreasing interaction:1378-1378,1375-1375	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P33611	uniprotkb:P33609	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-688051|ensembl:ENSMUSP00000006856	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:dpola_mouse(display_long)|uniprotkb:Pola1(gene name)|psi-mi:Pola1(display_short)|uniprotkb:Pola(gene name synonym)|uniprotkb:DNA polymerase alpha catalytic subunit p180(gene name synonym)	psi-mi:"MI:0027"(cosedimentation)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848981|imex:IM-20077-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032918.1|ensembl:ENSMUSG00000006678(gene)|ensembl:ENSMUST00000006856(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|interpro:IPR017964|interpro:IPR024647|interpro:IPR036397|interpro:IPR038256|interpro:IPR042087|interpro:IPR043502|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0000060"(obsolete protein import into nucleus, translocation)|go:"GO:0005658"("alpha DNA polymerase:primase complex")	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:6ZxRfRf1dB53T+WKCsAZNXQTTdE10090	intact-crc:F507FCB14A0562BC|rigid:ttw1t4uLY6fT7Okd7zdP7HuisBk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P33611	uniprotkb:P20664	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-848742|ensembl:ENSMUSP00000026461	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:pri1_mouse(display_long)|uniprotkb:DNA primase 49 kDa subunit(gene name synonym)|uniprotkb:Prim1(gene name)|psi-mi:Prim1(display_short)	psi-mi:"MI:0027"(cosedimentation)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848981|imex:IM-20077-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032947.1|ensembl:ENSMUSG00000025395(gene)|ensembl:ENSMUST00000026461(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032553"(ribonucleotide binding)|interpro:IPR002755(DNA primase, small subunit)|interpro:IPR014052(DNA primase, small subunit, eukaryotic and archaeal)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	go:"GO:0000060"(obsolete protein import into nucleus, translocation)|go:"GO:0005658"("alpha DNA polymerase:primase complex")	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:1ot482OC79gyXLWhgZIAppJwPzw10090	intact-crc:F507FCB14A0562BC|rigid:ttw1t4uLY6fT7Okd7zdP7HuisBk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P33611	uniprotkb:P33610	intact:EBI-848759|uniprotkb:Q8VDR3|ensembl:ENSMUSP00000025752	intact:EBI-848748|uniprotkb:Q3U4Z3|ensembl:ENSMUSP00000027312	psi-mi:dpoa2_mouse(display_long)|uniprotkb:DNA polymerase alpha 70 kDa subunit(gene name synonym)|uniprotkb:Pola2(gene name)|psi-mi:Pola2(display_short)	psi-mi:pri2_mouse(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:Prim2(gene name)|psi-mi:Prim2(display_short)	psi-mi:"MI:0027"(cosedimentation)	Mizuno et al. (1999)	pubmed:10523676|imex:IM-20077	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-848981|imex:IM-20077-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032919.2|ensembl:ENSMUSG00000024833(gene)|ensembl:ENSMUST00000025752(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006606"(protein import into nucleus)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|interpro:IPR043034|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183	refseq:NP_032948.1|ensembl:ENSMUSG00000026134(gene)|ensembl:ENSMUST00000027312(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|reactome:R-MMU-113501|reactome:R-MMU-174411|reactome:R-MMU-174430|reactome:R-MMU-68952|reactome:R-MMU-68962|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0046872"(metal ion binding)	go:"GO:0000060"(obsolete protein import into nucleus, translocation)|go:"GO:0005658"("alpha DNA polymerase:primase complex")	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells)	-	2006/02/07	2014/10/16	rogid:wtZ+CHV6De3pcMdP15WXGbvHWuI10090	rogid:OwusfGlmgCZF5zSS5MON0GSGwz810090	intact-crc:F507FCB14A0562BC|rigid:ttw1t4uLY6fT7Okd7zdP7HuisBk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)