#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9CQJ4	uniprotkb:Q8CCI5	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-929305|imex:IM-19615-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo)	-	2006/04/21	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:7FD0DCF1DA9FBED5|rigid:t/4MK99T5tIVcdDwCHgEdOUm41I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35730	uniprotkb:Q8CCI5	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-929337|imex:IM-19615-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo)	-	2006/04/21	2014/10/16	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:3704A28C590F0AB3|rigid:/4sGwy2uhPwMWioAlbGSAH39ZhQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:Q9CQJ4	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959498|imex:IM-19615-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryo)|taxid:10090(Mus musculus embryo)	-	2006/04/21	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:91DFA8999A7883E5|rigid:t/4MK99T5tIVcdDwCHgEdOUm41I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:O35730	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959329|imex:IM-19615-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	caution:The Ring1A protein AA 1and 2 did not correspond to amino acids 24 and 25 of the entry.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2006/04/21	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	intact-crc:BC72F4EF265C7878|rigid:/4sGwy2uhPwMWioAlbGSAH39ZhQ	false	-	sufficient binding region:24-227	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35730	uniprotkb:Q8CCI5	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959516|imex:IM-19615-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:4, 7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/21	2014/10/16	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:88CA23F5C33C9636|rigid:/4sGwy2uhPwMWioAlbGSAH39ZhQ	false	35s radiolabel:?-?|sufficient binding region:226-379	glutathione s tranferase tag:n-n|necessary binding region:160-174|sufficient binding region:158-177	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8CCI5	uniprotkb:P30658	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-360174|uniprotkb:O35731|uniprotkb:A2ABG2|ensembl:ENSMUSP00000026662|uniprotkb:Q8CIA0	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:cbx2_mouse(display_long)|uniprotkb:Cbx2(gene name)|psi-mi:Cbx2(display_short)|uniprotkb:M33(gene name synonym)|uniprotkb:Modifier 3 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959540|imex:IM-19615-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	ensembl:ENSMUSG00000025577(gene)|ensembl:ENSMUST00000026662(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR042796|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:NP_031649.2|dip:DIP-690N	-	-	-	figure legend:5B, 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/21	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:nUduKr4Vds3Ta6BDINRY2hFRweU10090	intact-crc:79BF3175336F5437|rigid:o8cm/mYDbs7B+tnQ5f2NAX2sp3c	false	glutathione s tranferase tag:n-n	35s radiolabel:?-?|sufficient binding region:1-119	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8CCI5	uniprotkb:P25490	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959561|imex:IM-19615-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490	-	-	-	comment:Two independent sites AA42-118 and AA207-227 of Rybp are involved in this interaction|figure legend:7|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/21	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606	intact-crc:B373BD117D514AB1|rigid:9MUx9gFgPzeDauj2rVCNNQhXzWA	false	sufficient binding region:207-227|glutathione s tranferase tag:n-n|sufficient binding region:42-118	35s radiolabel:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30658	uniprotkb:O35730	intact:EBI-360174|uniprotkb:O35731|uniprotkb:A2ABG2|ensembl:ENSMUSP00000026662|uniprotkb:Q8CIA0	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	psi-mi:cbx2_mouse(display_long)|uniprotkb:Cbx2(gene name)|psi-mi:Cbx2(display_short)|uniprotkb:M33(gene name synonym)|uniprotkb:Modifier 3 protein(gene name synonym)	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1108553|imex:IM-19615-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025577(gene)|ensembl:ENSMUST00000026662(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR042796|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:NP_031649.2|dip:DIP-690N	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/21	2014/10/16	rogid:nUduKr4Vds3Ta6BDINRY2hFRweU10090	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	intact-crc:8B76B3D7AB7679C7|rigid:tpjz80qNeO3oLVzNZAmtuTHTHb8	false	sufficient binding region:333-519|35s radiolabel:?-?	glutathione s tranferase tag:?-?|sufficient binding region:1-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P30658	uniprotkb:Q8CCI5	intact:EBI-360174|uniprotkb:O35731|uniprotkb:A2ABG2|ensembl:ENSMUSP00000026662|uniprotkb:Q8CIA0	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:cbx2_mouse(display_long)|uniprotkb:Cbx2(gene name)|psi-mi:Cbx2(display_short)|uniprotkb:M33(gene name synonym)|uniprotkb:Modifier 3 protein(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1108751|imex:IM-19615-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025577(gene)|ensembl:ENSMUST00000026662(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR042796|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:NP_031649.2|dip:DIP-690N	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:7|comment:Two binding domains 42-118 and 207-227 are involved in Rybp and Cbx2 interaction.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/04/21	2014/10/16	rogid:nUduKr4Vds3Ta6BDINRY2hFRweU10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:32C54DB1A2CF3AA0|rigid:o8cm/mYDbs7B+tnQ5f2NAX2sp3c	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n|sufficient binding region:42-118|sufficient binding region:207-227	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8CCI5	uniprotkb:P30658	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-360174|uniprotkb:O35731|uniprotkb:A2ABG2|ensembl:ENSMUSP00000026662|uniprotkb:Q8CIA0	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:cbx2_mouse(display_long)|uniprotkb:Cbx2(gene name)|psi-mi:Cbx2(display_short)|uniprotkb:M33(gene name synonym)|uniprotkb:Modifier 3 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959579|imex:IM-19615-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	ensembl:ENSMUSG00000025577(gene)|ensembl:ENSMUST00000026662(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR042796|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:NP_031649.2|dip:DIP-690N	-	-	-	figure legend:5A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/04/21	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:nUduKr4Vds3Ta6BDINRY2hFRweU10090	intact-crc:8A1F3787D839C09A|rigid:o8cm/mYDbs7B+tnQ5f2NAX2sp3c	false	glutathione s tranferase tag:n-n	ha tag:n-n|sufficient binding region:1-119	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:P25490	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959673|imex:IM-19615-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490	-	-	-	figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/04/21	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606	intact-crc:B347B24C747069A0|rigid:9MUx9gFgPzeDauj2rVCNNQhXzWA	false	glutathione s tranferase tag:n-n	sufficient binding region:272-414|myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8ST83	uniprotkb:Q8CCI5	intact:EBI-125201|uniprotkb:A4V138|uniprotkb:Q6W466|uniprotkb:Q6W467|uniprotkb:Q6W470|uniprotkb:Q6W480|uniprotkb:Q6W485|uniprotkb:O76247|uniprotkb:Q9V4A3|ensemblmetazoa:FBpp0088268|ensemblmetazoa:FBpp0088269	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:pho_drome(display_long)|uniprotkb:pho(gene name)|psi-mi:pho(display_short)|uniprotkb:CG17743(orf name)|uniprotkb:Protein pleiohomeotic(gene name synonym)|uniprotkb:Transcription factor YY1 homolog(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Garcia et al. (1999)	pubmed:10369680|imex:IM-19615	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-959684|imex:IM-19615-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_524630.1|refseq:NP_726651.1|flybase:FBgn0002521|ensemblmetazoa:FBgn0002521(gene)|ensemblmetazoa:FBtr0089204(transcript)|ensemblmetazoa:FBtr0089205(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048096"|go:"GO:0048813"(dendrite morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:4C5E|rcsb pdb:4C5G|rcsb pdb:4C5H|go:"GO:0005704"(polytene chromosome band)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|reactome:R-DME-5696394|reactome:R-DME-5689603|dip:DIP-20923N	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	caution:The aminoacid numbering for the drosophila PHO protein is as described by the authors. The UniProtKB entry is longer.|figure legend:6|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2006/04/21	2014/10/16	rogid:Tg2SZvO0PyYvGgNAnpp+INan7hw7227	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:850197D714FC4564|rigid:OYf5fQrQE5GkFYovhczl2KcMAfw	false	sufficient binding region:1-474|ha tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)