#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9WVJ4 uniprotkb:O55207-3 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 intact:EBI-7007476|intact:MINT-132561 psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:"MI:0018"(two hybrid) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7007487|mint:MINT-1792069|imex:IM-14031-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792071(identity) intact:EBI-8743673(isoform-parent)|mint:MINT-1792070(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" figure legend:NFA|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/29 2014/10/16 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 intact-crc:75068F3498EA5065|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false tag:?-?(MINT-1792080) binding-associated region:1030-1248(MINT-1792097)|tag:?-?(MINT-1792090) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55207-3 uniprotkb:Q9WVJ4 intact:EBI-7007476|intact:MINT-132561 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7007523|mint:MINT-1792304|imex:IM-14031-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8743673(isoform-parent)|mint:MINT-1792305(identity) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792318(identity) - isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/03/29 2014/10/16 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 intact-crc:60A67063D6B639B5|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false tag:?-?(MINT-1792316)|mutation disrupting interaction:1293-1293(MINT-1792310)|mutation disrupting interaction:1291-1291(MINT-1792308)|mutation disrupting interaction:1290-1290(MINT-1792306) tag:?-?(MINT-1792319)|binding-associated region:1-116(MINT-1792325) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55207-3 uniprotkb:Q9WVJ4 intact:EBI-7007476|intact:MINT-132561 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:"MI:0049"(filter binding) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7007593|mint:MINT-1792100|imex:IM-14031-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8743673(isoform-parent)|mint:MINT-1792101(identity) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792111(identity) - isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2014/10/16 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 intact-crc:DDBB16842DF8A453|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false flag tag:?-?(MINT-1792109) binding-associated region:1-116(MINT-1792149)|glutathione s tranferase tag:?-?(MINT-1792117) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55207-3 uniprotkb:Q9WVJ4 intact:EBI-7007476|intact:MINT-132561 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:"MI:0049"(filter binding) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7007648|mint:MINT-1792181|imex:IM-14031-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8743673(isoform-parent)|mint:MINT-1792182(identity) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792188(identity) - isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2014/10/16 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 intact-crc:E7CEC13CF9295BBF|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false maltose binding protein tag:?-?(MINT-1792206)|binding-associated region:1172-1248(MINT-1792208) binding-associated region:1-116(MINT-1792195)|glutathione s tranferase tag:?-?(MINT-1792189) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WVJ4 uniprotkb:O55207-3 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 intact:EBI-7007476|intact:MINT-132561 psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:"MI:0049"(filter binding) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7007674|mint:MINT-1792273|imex:IM-14031-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792283(identity) intact:EBI-8743673(isoform-parent)|mint:MINT-1792274(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2014/10/16 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 intact-crc:D823A682CE28D432|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false binding-associated region:1-116(MINT-1792284)|glutathione s tranferase tag:?-?(MINT-1792291) maltose binding protein tag:?-?(MINT-1792281)|mutation disrupting interaction:1291-1291(MINT-1792299)|mutation disrupting interaction:1293-1293(MINT-1792297)|mutation disrupting interaction:1290-1290(MINT-1792301) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WVJ4 uniprotkb:O55207-3 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 intact:EBI-7007476|intact:MINT-132561 psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:"MI:0096"(pull down) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7007721|mint:MINT-1792154|imex:IM-14031-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792163(identity) intact:EBI-8743673(isoform-parent)|mint:MINT-1792155(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2014/10/16 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 intact-crc:8B8D1C62D8FEFC76|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false binding-associated region:1-116(MINT-1792164)|glutathione s tranferase tag:?-?(MINT-1792171) - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q9WVJ4 uniprotkb:O55207-3 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 intact:EBI-7007476|intact:MINT-132561 psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:"MI:0096"(pull down) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7007755|mint:MINT-1792211|imex:IM-14031-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792221(identity) intact:EBI-8743673(isoform-parent)|mint:MINT-1792212(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2014/10/16 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 intact-crc:5484DCA9E9EC0F4C|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false glutathione s tranferase tag:?-?(MINT-1792229)|binding-associated region:1-116(MINT-1792222) binding-associated region:1277-1293(MINT-1792213)|maltose binding protein tag:?-?(MINT-1792219) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O55207-3 uniprotkb:Q9WVJ4 intact:EBI-7007476|intact:MINT-132561 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7007791|mint:MINT-1792244|imex:IM-14031-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-8743673(isoform-parent)|mint:MINT-1792245(identity) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792254(identity) - isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F2E|kinetics:IC50 21 nanomolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/03/29 2014/10/16 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 intact-crc:4A25F45DCA76C9B9|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false maltose binding protein tag:?-?(MINT-1792252)|binding-associated region:1277-1293(MINT-1792246) glutathione s tranferase tag:?-?(MINT-1792255)|binding-associated region:1-116(MINT-1792261) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9WVJ4 uniprotkb:O55207-3 intact:EBI-7007454|ensembl:ENSRNOP00000009119|intact:MINT-1216281|uniprotkb:A0JN00 intact:EBI-7007476|intact:MINT-132561 psi-mi:syj2b_rat(display_long)|uniprotkb:Synj2bp(gene name)|psi-mi:Synj2bp(display_short)|uniprotkb:Omp25(gene name synonym)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:NPW16(gene name synonym) psi-mi:o55207-3(display_long)|uniprotkb:Synj2(gene name)|psi-mi:Synj2(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym)|uniprotkb:7.5kb(isoform synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nemoto et al. (1999) pubmed:10357812|imex:IM-14031|mint:MINT-5211522 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7007828|mint:MINT-1792336|imex:IM-14031-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000006399(gene)|ensembl:ENSRNOT00000009122(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005739"(mitochondrion)|go:"GO:0006605"(protein targeting)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rgd:69400|refseq:NP_072121.2|mint:MINT-1792351(identity) intact:EBI-8743673(isoform-parent)|mint:MINT-1792337(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:The PDZ domain of isoform 2A binds SYNJ2BP/OMP25. Mutagenesis of Ser-1246 or Val-1248 to Ala abolishes SYNJ2BP/OMP25 binding.|comment:mint|comment:"Stoichiometry: 1.0" figure legend:F8B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)") - 2006/03/29 2014/10/16 rogid:7sdA4a6pd1W35wxHkRhUcOMDQr410116 rogid:JtAezRBUTXGR3rmml63vle5DtIE10116 intact-crc:53CFEC47FBBAD045|rigid:yAFNBNV+WeHjY995sDeAuQJdGYI false ha tag:?-?(MINT-1792360) flag tag:?-?(MINT-1792349) 1 1 psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)