#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P00968	uniprotkb:P0A6F1	intact:EBI-546118|ensemblbacteria:AAC73144|ensemblbacteria:BAB96602	intact:EBI-546107|ensemblbacteria:AAC73143|ensemblbacteria:BAB96601|uniprotkb:P00907	psi-mi:carb_ecoli(display_long)|uniprotkb:carB(gene name)|psi-mi:carB(display_short)|uniprotkb:pyrA(gene name synonym)|uniprotkb:b0033(locus name)|uniprotkb:Carbamoyl-phosphate synthetase ammonia chain(gene name synonym)|uniprotkb:JW0031(locus name)	psi-mi:cara_ecoli(display_long)|uniprotkb:carA(gene name)|psi-mi:carA(display_short)|uniprotkb:pyrA(gene name synonym)|uniprotkb:b0032(locus name)|uniprotkb:Carbamoyl-phosphate synthetase glutamine chain(gene name synonym)|uniprotkb:JW0030(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Thoden et al. (1999)	pubmed:10029528|imex:IM-18675	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1027640|rcsb pdb:1BXR|imex:IM-18675-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC73144(transcript)|ensemblbacteria:b0033(gene)|ensemblbacteria:BAB96602(gene)|ensemblbacteria:BAB96602(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004087"("carbamoyl-phosphate synthase (ammonia) activity")|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005951"(carbamoyl-phosphate synthase complex)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR033937|interpro:IPR036897|interpro:IPR036914|rcsb pdb:1A9X|rcsb pdb:1BXR|rcsb pdb:1C30|rcsb pdb:1C3O|rcsb pdb:1CE8|rcsb pdb:1CS0|rcsb pdb:1JDB|rcsb pdb:1KEE|rcsb pdb:1M6V|rcsb pdb:1T36|refseq:NP_414574.1|refseq:WP_001126348.1|dip:DIP-1025N	ensemblbacteria:AAC73143(transcript)|ensemblbacteria:b0032(gene)|ensemblbacteria:BAB96601(gene)|ensemblbacteria:BAB96601(transcript)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005951"(carbamoyl-phosphate synthase complex)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR017926|interpro:IPR029062|interpro:IPR035686|interpro:IPR036480|rcsb pdb:1A9X|rcsb pdb:1BXR|rcsb pdb:1C30|rcsb pdb:1C3O|rcsb pdb:1CE8|rcsb pdb:1CS0|rcsb pdb:1JDB|rcsb pdb:1KEE|rcsb pdb:1M6V|rcsb pdb:1T36|refseq:NP_414573.1|refseq:WP_000597260.1|dip:DIP-35412N	-	-	-	3d-r-factors:Rfree = 0.2 Rworking = 0.2|3d-resolution:2.1A|figure legend:Table 1|dataset:PDBe - Data obtained from the Protein Data Bank Europe|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:v4ATo4+Ge+q27kVj8F36bTEu2Gw83333	rogid:R50k6IyBn3KrvO5c5PElb0GX/lk83333	intact-crc:87B962543EFC0FF0|rigid:DrN168EEHgIr84cPcLf5CaVQbow	false	sufficient binding region:2-1073	sufficient binding region:1-382	4	4	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)