#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P06722 uniprotkb:P23367 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0018"(two hybrid) Hall et al. (1999) pubmed:9880500|mint:MINT-6548456 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-761694 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC go:"GO:0006298"(mismatch repair) - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/28 2014/10/16 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:F97F5B79526C37AD|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - sufficient binding region:439-615|necessary binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23367 uniprotkb:P06722 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:"MI:0018"(two hybrid) Hall et al. (1999) pubmed:9880500|mint:MINT-6548456 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-762624 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N go:"GO:0006298"(mismatch repair) - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/28 2014/10/16 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 intact-crc:E37FF2910B0991C4|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - necessary binding region:?-?|necessary binding region:2-39 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06722 uniprotkb:P23367 intact:EBI-545170|uniprotkb:Q2MA06|uniprotkb:Q9R2X2|uniprotkb:Q9R3A8|uniprotkb:Q9R411|uniprotkb:Q9S6P5|uniprotkb:Q9S6P6|uniprotkb:Q9S6P7|ensemblbacteria:AAC75870|ensemblbacteria:BAE76900 intact:EBI-554913|uniprotkb:Q2M6D5|ensemblbacteria:AAC77127|ensemblbacteria:BAE78171 psi-mi:muth_ecoli(display_long)|uniprotkb:mutH(gene name)|psi-mi:mutH(display_short)|uniprotkb:mutR(gene name synonym)|uniprotkb:prv(gene name synonym)|uniprotkb:b2831(locus name)|uniprotkb:Methyl-directed mismatch repair protein(gene name synonym)|uniprotkb:JW2799(locus name) psi-mi:mutl_ecoli(display_long)|uniprotkb:mutL(gene name)|psi-mi:mutL(display_short)|uniprotkb:b4170(locus name)|uniprotkb:JW4128(locus name) psi-mi:"MI:0004"(affinity chromatography technology) Hall et al. (1999) pubmed:9880500|mint:MINT-6548456 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-761711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000018"(regulation of DNA recombination)|ensemblbacteria:BAE76900(transcript)|ensemblbacteria:AAC75870(transcript)|ensemblbacteria:b2831(gene)|ensemblbacteria:BAE76900(gene)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006304"(DNA modification)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0043765"(T/G mismatch-specific endonuclease activity)|interpro:IPR004230(DNA mismatch repair protein MutH)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011337(Restriction endonuclease, type II, EcoRV-like/DNA mismatch repair MutH, core)|interpro:IPR037057|rcsb pdb:1AZO|rcsb pdb:2AZO|go:"GO:0003677"(DNA binding)|refseq:NP_417308.1|refseq:WP_000082201.1|dip:DIP-10284N refseq:NP_418591.1|refseq:WP_001122505.1|dip:DIP-10285N|ensemblbacteria:AAC77127(transcript)|ensemblbacteria:b4170(gene)|ensemblbacteria:BAE78171(gene)|ensemblbacteria:BAE78171(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006298"(mismatch repair)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0042802"(identical protein binding)|interpro:IPR002099(DNA mismatch repair protein)|interpro:IPR013507(DNA mismatch repair protein, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR014762(DNA mismatch repair, conserved site)|interpro:IPR014790(MutL, C-terminal, dimerisation)|interpro:IPR020568|interpro:IPR020667|interpro:IPR036890|interpro:IPR037198|interpro:IPR038973|interpro:IPR042120|interpro:IPR042121|rcsb pdb:1B62|rcsb pdb:1B63|rcsb pdb:1BKN|rcsb pdb:1NHH|rcsb pdb:1NHI|rcsb pdb:1NHJ|rcsb pdb:1X9Z|rcsb pdb:5AKB|rcsb pdb:5AKC|rcsb pdb:5AKD|rcsb pdb:6E8E|rcsb pdb:7AIB|rcsb pdb:7AIC go:"GO:0006298"(mismatch repair) - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/28 2014/10/16 rogid:ImnYkXur2U4xVdz5PVvprq8Zgd483333 rogid:hhZYhMtr5JC1lGIKtR1wxHAd3JY83333 intact-crc:405EB143C97A54FF|rigid:1gV7goLXeCXg0TLAfsnNcwP8LGE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)