#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O61667	uniprotkb:P41958	intact:EBI-495949|uniprotkb:Q7JLC9|ensemblmetazoa:F23B12.9.1	intact:EBI-494110|ensemblmetazoa:T07C4.8.1	psi-mi:egl1_caeel(display_long)|uniprotkb:Egg-laying defective protein 1(gene name synonym)|uniprotkb:egl-1(gene name)|psi-mi:egl-1(display_short)|uniprotkb:F23B12.9(orf name)	psi-mi:ced9_caeel(display_long)|uniprotkb:Cell death protein 9(gene name synonym)|uniprotkb:ced-9(gene name)|psi-mi:ced-9(display_short)|uniprotkb:T07C4.8(orf name)	psi-mi:"MI:0018"(two hybrid)	Conradt et al. (1998)	pubmed:9604928|mint:MINT-6547878	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-495954	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_506575.2|wormbase:F23B12.9|interpro:IPR021543|rcsb pdb:1TY4|ensemblmetazoa:F23B12.9.1(transcript)|ensemblmetazoa:WBGene00001170(gene)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0018991"(oviposition)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0098793"(presynapse)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:1905808"(positive regulation of synapse pruning)	refseq:NP_499284.1|wormbase:T07C4.8|ensemblmetazoa:T07C4.8.1(transcript)|ensemblmetazoa:WBGene00000423(gene)|go:"GO:0000422"(autophagy of mitochondrion)|reactome:R-CEL-9648002|dip:DIP-250N|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031090"(organelle membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043204"(perikaryon)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098793"(presynapse)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:1905808"(positive regulation of synapse pruning)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR020717|interpro:IPR026298|interpro:IPR036834|rcsb pdb:1OHU|rcsb pdb:1TY4|rcsb pdb:2A5Y	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/02/25	2014/10/16	rogid:M1NJ7kcUPROwBXN7H90MiFEYvh46239	rogid:0nKuipvqQOKHVeaoNXbSFYJNPhM6239	intact-crc:E2C13C071537B24C|rigid:J6TqE3VgwAsc774cEVYHZCJEca0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O61667	uniprotkb:P41958	intact:EBI-495949|uniprotkb:Q7JLC9|ensemblmetazoa:F23B12.9.1	intact:EBI-494110|ensemblmetazoa:T07C4.8.1	psi-mi:egl1_caeel(display_long)|uniprotkb:Egg-laying defective protein 1(gene name synonym)|uniprotkb:egl-1(gene name)|psi-mi:egl-1(display_short)|uniprotkb:F23B12.9(orf name)	psi-mi:ced9_caeel(display_long)|uniprotkb:Cell death protein 9(gene name synonym)|uniprotkb:ced-9(gene name)|psi-mi:ced-9(display_short)|uniprotkb:T07C4.8(orf name)	psi-mi:"MI:0096"(pull down)	Conradt et al. (1998)	pubmed:9604928|mint:MINT-6547878	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-495967	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_506575.2|wormbase:F23B12.9|interpro:IPR021543|rcsb pdb:1TY4|ensemblmetazoa:F23B12.9.1(transcript)|ensemblmetazoa:WBGene00001170(gene)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0018991"(oviposition)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0098793"(presynapse)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:1905808"(positive regulation of synapse pruning)	refseq:NP_499284.1|wormbase:T07C4.8|ensemblmetazoa:T07C4.8.1(transcript)|ensemblmetazoa:WBGene00000423(gene)|go:"GO:0000422"(autophagy of mitochondrion)|reactome:R-CEL-9648002|dip:DIP-250N|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031090"(organelle membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043204"(perikaryon)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098793"(presynapse)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:1905808"(positive regulation of synapse pruning)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR020717|interpro:IPR026298|interpro:IPR036834|rcsb pdb:1OHU|rcsb pdb:1TY4|rcsb pdb:2A5Y	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/02/25	2014/10/16	rogid:M1NJ7kcUPROwBXN7H90MiFEYvh46239	rogid:0nKuipvqQOKHVeaoNXbSFYJNPhM6239	intact-crc:1AD2F32F56544413|rigid:J6TqE3VgwAsc774cEVYHZCJEca0	false	radiolabel:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P41958	uniprotkb:O61667	intact:EBI-494110|ensemblmetazoa:T07C4.8.1	intact:EBI-495949|uniprotkb:Q7JLC9|ensemblmetazoa:F23B12.9.1	psi-mi:ced9_caeel(display_long)|uniprotkb:Cell death protein 9(gene name synonym)|uniprotkb:ced-9(gene name)|psi-mi:ced-9(display_short)|uniprotkb:T07C4.8(orf name)	psi-mi:egl1_caeel(display_long)|uniprotkb:Egg-laying defective protein 1(gene name synonym)|uniprotkb:egl-1(gene name)|psi-mi:egl-1(display_short)|uniprotkb:F23B12.9(orf name)	psi-mi:"MI:0096"(pull down)	Conradt et al. (1998)	pubmed:9604928|mint:MINT-6547878	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-495976	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_499284.1|wormbase:T07C4.8|ensemblmetazoa:T07C4.8.1(transcript)|ensemblmetazoa:WBGene00000423(gene)|go:"GO:0000422"(autophagy of mitochondrion)|reactome:R-CEL-9648002|dip:DIP-250N|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031090"(organelle membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043204"(perikaryon)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0090727"(positive regulation of brood size)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0098793"(presynapse)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1901046"(positive regulation of oviposition)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:1905808"(positive regulation of synapse pruning)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR003093(Apoptosis regulator Bcl-2 protein, BH4)|interpro:IPR020717|interpro:IPR026298|interpro:IPR036834|rcsb pdb:1OHU|rcsb pdb:1TY4|rcsb pdb:2A5Y	refseq:NP_506575.2|wormbase:F23B12.9|interpro:IPR021543|rcsb pdb:1TY4|ensemblmetazoa:F23B12.9.1(transcript)|ensemblmetazoa:WBGene00001170(gene)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0018991"(oviposition)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0098793"(presynapse)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:1904747"(positive regulation of apoptotic process involved in development)|go:"GO:1905808"(positive regulation of synapse pruning)	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/02/25	2014/10/16	rogid:0nKuipvqQOKHVeaoNXbSFYJNPhM6239	rogid:M1NJ7kcUPROwBXN7H90MiFEYvh46239	intact-crc:B0AC89D7D4369084|rigid:J6TqE3VgwAsc774cEVYHZCJEca0	false	glutathione s tranferase tag:?-?	radiolabel:?-?|binding-associated region:74-106(IPR000712)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)