#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04150 uniprotkb:P51532 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fryer et al. (1998) pubmed:9590696 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-493544 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - - agonist:Glucocorticoid treatment.|antagonist:Antiprogestin treatment.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:9606(human-t47d)|taxid:9606(human breast cancer tumour cell line-epithelial cells) - 2005/02/18 2014/10/16 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 intact-crc:D4BCF11073C8D741|rigid:DerytK+XQDEN+pBoW0T/FhpWPbM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04150 uniprotkb:Q92922 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Fryer et al. (1998) pubmed:9590696 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-493549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - - - stimulant:By glucococorticoid treatment.|inhibition:By antiprogestin treatment.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:9606(human-t47d)|taxid:9606(human breast cancer tumour cell line-epithelial cells) - 2005/02/18 2014/10/16 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 intact-crc:055AF64224FC2313|rigid:jFnzecovq3m/ipCS6Q38c4CK+nY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)