#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21461	uniprotkb:P21461	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529020	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	intact-crc:69F33C7C60D7BA40|rigid:+vjSk86AURqxS6iRv0GVSzBuM7I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21461	uniprotkb:Q27934	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529033	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	intact-crc:BB626C6F597CCDFD|rigid:P+ui+n2mQlnO4IJGO8pz4sikPeE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21461	uniprotkb:Q27934	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	intact-crc:3CF4615BDD3EA73D|rigid:P+ui+n2mQlnO4IJGO8pz4sikPeE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q27934	uniprotkb:Q27934	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529043	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	intact-crc:08B8359606783E6E|rigid:q0wX2yzUaD/Xh3xoA2/tuURxoso	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42282	uniprotkb:Q27934	intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym)	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529048	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	intact-crc:E4AF05A5403C425C|rigid:BOVWQsZ94fnH2c3IX5GJ9XqoIwg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42282	uniprotkb:P21461	intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym)	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529054	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	intact-crc:5AE83AF229270493|rigid:JmGFe1Hey/BKCxM3CMGCYTEOMr8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21461	uniprotkb:P25867	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	intact:EBI-196394|uniprotkb:Q9VFG6|ensemblmetazoa:FBpp0082477|ensemblmetazoa:FBpp0302691|ensemblmetazoa:FBpp0307824	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:ubcd1_drome(display_long)|uniprotkb:eff(gene name)|psi-mi:eff(display_short)|uniprotkb:UbcD1(gene name synonym)|uniprotkb:CG7425(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Protein effete(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529057	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	refseq:NP_001262578.1|refseq:NP_001262579.1|refseq:NP_731941.1|flybase:FBgn0011217|dip:DIP-18953N|ensemblmetazoa:FBgn0011217(gene)|ensemblmetazoa:FBtr0083018(transcript)|ensemblmetazoa:FBtr0310554(transcript)|ensemblmetazoa:FBtr0336876(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051276"(chromosome organization)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1234176|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176412|reactome:R-DME-179409|reactome:R-DME-201451|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-5689896|reactome:R-DME-69017|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8951664|reactome:R-DME-9033241|reactome:R-DME-983168	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	rogid:m591n40BVy1LgRJXj1+X1FvIbzc7227	intact-crc:E5C6963644BFC58B|rigid:YKUB4dWpympzEGOLvSW3snuO9FI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21461	uniprotkb:P25867	intact:EBI-77019|uniprotkb:A4V214|uniprotkb:Q9VVB0|ensemblmetazoa:FBpp0075091|ensemblmetazoa:FBpp0075092|ensemblmetazoa:FBpp0310636	intact:EBI-196394|uniprotkb:Q9VFG6|ensemblmetazoa:FBpp0082477|ensemblmetazoa:FBpp0302691|ensemblmetazoa:FBpp0307824	psi-mi:sina_drome(display_long)|uniprotkb:sina(gene name)|psi-mi:sina(display_short)|uniprotkb:CG9949(orf name)|uniprotkb:Seven in absentia protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase sina(gene name synonym)	psi-mi:ubcd1_drome(display_long)|uniprotkb:eff(gene name)|psi-mi:eff(display_short)|uniprotkb:UbcD1(gene name synonym)|uniprotkb:CG7425(orf name)|uniprotkb:Ubiquitin-protein ligase(gene name synonym)|uniprotkb:Ubiquitin carrier protein(gene name synonym)|uniprotkb:Protein effete(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529060	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476725.1|refseq:NP_730206.1|flybase:FBgn0003410|refseq:NP_001287089.1|dip:DIP-17392N|ensemblmetazoa:FBgn0003410(gene)|ensemblmetazoa:FBtr0075332(transcript)|ensemblmetazoa:FBtr0075333(transcript)|ensemblmetazoa:FBtr0344230(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007423"(sensory organ development)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR004162(Seven in absentia protein)|interpro:IPR008974(TRAF-like)|interpro:IPR013010(Zinc finger, SIAH-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018121|reactome:R-DME-373752|reactome:R-DME-5689880|reactome:R-DME-983168	refseq:NP_001262578.1|refseq:NP_001262579.1|refseq:NP_731941.1|flybase:FBgn0011217|dip:DIP-18953N|ensemblmetazoa:FBgn0011217(gene)|ensemblmetazoa:FBtr0083018(transcript)|ensemblmetazoa:FBtr0310554(transcript)|ensemblmetazoa:FBtr0336876(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0001751"(compound eye photoreceptor cell differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0045676"(regulation of R7 cell differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0051276"(chromosome organization)|go:"GO:0061057"(peptidoglycan recognition protein signaling pathway)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0097039"(protein linear polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-DME-1234176|reactome:R-DME-141430|reactome:R-DME-174048|reactome:R-DME-174084|reactome:R-DME-174154|reactome:R-DME-174178|reactome:R-DME-174184|reactome:R-DME-176407|reactome:R-DME-176408|reactome:R-DME-176409|reactome:R-DME-176412|reactome:R-DME-179409|reactome:R-DME-201451|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-2173795|reactome:R-DME-2467813|reactome:R-DME-2559582|reactome:R-DME-5689896|reactome:R-DME-69017|reactome:R-DME-8866652|reactome:R-DME-8866654|reactome:R-DME-8951664|reactome:R-DME-9033241|reactome:R-DME-983168	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/04/12	2014/10/16	rogid:GmUKLSW+fhn/1Fkti+v7o+NWs/87227	rogid:m591n40BVy1LgRJXj1+X1FvIbzc7227	intact-crc:62509B02C0FDAF4B|rigid:YKUB4dWpympzEGOLvSW3snuO9FI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q27934	uniprotkb:P42282	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529065	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	-	-	-	-	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2005/04/12	2014/10/16	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227	intact-crc:D62B031D281832F1|rigid:BOVWQsZ94fnH2c3IX5GJ9XqoIwg	false	tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q27934	uniprotkb:P42282	intact:EBI-77033|uniprotkb:Q9V721|uniprotkb:C0PV22|ensemblmetazoa:FBpp0086645	intact:EBI-77008|uniprotkb:A4V3Q3|uniprotkb:Q0KHY0|uniprotkb:Q1LZ43|uniprotkb:Q24313|uniprotkb:Q9V9V2|ensemblmetazoa:FBpp0085186|ensemblmetazoa:FBpp0085188|ensemblmetazoa:FBpp0085190|ensemblmetazoa:FBpp0292319	psi-mi:phyl_drome(display_long)|uniprotkb:phyl(gene name)|psi-mi:phyl(display_short)|uniprotkb:CG10108(orf name)	psi-mi:ttka_drome(display_long)|uniprotkb:ttk(gene name)|psi-mi:ttk(display_short)|uniprotkb:FTZ-F2(gene name synonym)|uniprotkb:CG1856(orf name)|uniprotkb:Tramtrack p88(gene name synonym)|uniprotkb:Repressor protein fushi tarazu(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tang et al. (1997)	pubmed:9267026	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-529072	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_725394.1|flybase:FBgn0013725|dip:DIP-29101N|ensemblmetazoa:FBgn0013725(gene)|ensemblmetazoa:FBtr0087516(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007423"(sensory organ development)|go:"GO:0007462"(R1/R6 cell fate commitment)|go:"GO:0007465"(R7 cell fate commitment)|go:"GO:0007601"(visual perception)|go:"GO:0008052"(sensory organ boundary specification)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|rcsb pdb:4I7B|rcsb pdb:4I7C|rcsb pdb:4I7D	refseq:NP_001189329.1|refseq:NP_733443.1|refseq:NP_733444.1|refseq:NP_733445.1|flybase:FBgn0003870|ensemblmetazoa:FBgn0003870(gene)|ensemblmetazoa:FBtr0085825(transcript)|ensemblmetazoa:FBtr0085827(transcript)|ensemblmetazoa:FBtr0085829(transcript)|ensemblmetazoa:FBtr0303227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005700"(polytene chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007426"(tracheal outgrowth, open tracheal system)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031208"(POZ domain binding)|go:"GO:0035001"(dorsal trunk growth, open tracheal system)|go:"GO:0035147"(branch fusion, open tracheal system)|go:"GO:0035151"(regulation of tube size, open tracheal system)|go:"GO:0035883"(enteroendocrine cell differentiation)|go:"GO:0040003"(chitin-based cuticle development)|go:"GO:0042675"(compound eye cone cell differentiation)|go:"GO:0042682"(regulation of compound eye cone cell fate specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045500"(sevenless signaling pathway)|go:"GO:0045677"(negative regulation of R7 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046843"(dorsal appendage formation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048053"(R1/R6 development)|go:"GO:0048626"(myoblast fate specification)|go:"GO:0048750"(compound eye corneal lens morphogenesis)|go:"GO:0060446"(branching involved in open tracheal system development)|go:"GO:1903688"(positive regulation of border follicle cell migration)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236	-	-	-	-	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2005/04/12	2014/10/16	rogid:QocGYm5CUc0c4Z8raybzOGhpt1M7227	rogid:k0MeF2/ch3ddqz7uLHjP8aeJwoI7227	intact-crc:9B97751D2DD86999|rigid:BOVWQsZ94fnH2c3IX5GJ9XqoIwg	false	tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)