#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O15304	uniprotkb:P26842	intact:EBI-520756|uniprotkb:Q96P98|uniprotkb:Q9UPD6|ensembl:ENSP00000329213	intact:EBI-520729|uniprotkb:B2RDZ0|ensembl:ENSP00000266557	psi-mi:siva_human(display_long)|uniprotkb:CD27-binding protein(gene name synonym)|uniprotkb:SIVA1(gene name)|psi-mi:SIVA1(display_short)|uniprotkb:SIVA(gene name synonym)	psi-mi:cd27_human(display_long)|uniprotkb:CD27L receptor(gene name synonym)|uniprotkb:T-cell activation antigen CD27(gene name synonym)|uniprotkb:T14(gene name synonym)|uniprotkb:Tumor necrosis factor receptor superfamily member 7(gene name synonym)|uniprotkb:CD27(gene name)|psi-mi:CD27(display_short)|uniprotkb:TNFRSF7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Prasad et al. (1997)	pubmed:9177220	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-520752	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006418.2|refseq:NP_068355.1|ensembl:ENSG00000184990(gene)|ensembl:ENST00000329967(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005175"(CD27 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR022773|mint:O15304	refseq:NP_001233.1|ensembl:ENSG00000139193(gene)|ensembl:ENST00000266557(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022328|interpro:IPR034000|rcsb pdb:5TL5|rcsb pdb:5TLJ|rcsb pdb:5TLK|reactome:R-HSA-5669034	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/03/21	2014/10/16	rogid:ZSaEOpu8SYAilgfYzcK/EGgUoiI9606	rogid:7kwsm9SZO70EBVpV0lNGNo6zxeE9606	intact-crc:96B9D5AD9C3AEA0E|rigid:AKC2z8jyihwJhekBNn4X53oZeJs	false	-	binding-associated region:193-241	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P26842	uniprotkb:O15304	intact:EBI-520729|uniprotkb:B2RDZ0|ensembl:ENSP00000266557	intact:EBI-520756|uniprotkb:Q96P98|uniprotkb:Q9UPD6|ensembl:ENSP00000329213	psi-mi:cd27_human(display_long)|uniprotkb:CD27L receptor(gene name synonym)|uniprotkb:T-cell activation antigen CD27(gene name synonym)|uniprotkb:T14(gene name synonym)|uniprotkb:Tumor necrosis factor receptor superfamily member 7(gene name synonym)|uniprotkb:CD27(gene name)|psi-mi:CD27(display_short)|uniprotkb:TNFRSF7(gene name synonym)	psi-mi:siva_human(display_long)|uniprotkb:CD27-binding protein(gene name synonym)|uniprotkb:SIVA1(gene name)|psi-mi:SIVA1(display_short)|uniprotkb:SIVA(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Prasad et al. (1997)	pubmed:9177220	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-520781	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001233.1|ensembl:ENSG00000139193(gene)|ensembl:ENST00000266557(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022328|interpro:IPR034000|rcsb pdb:5TL5|rcsb pdb:5TLJ|rcsb pdb:5TLK|reactome:R-HSA-5669034	refseq:NP_006418.2|refseq:NP_068355.1|ensembl:ENSG00000184990(gene)|ensembl:ENST00000329967(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005175"(CD27 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|interpro:IPR022773|mint:O15304	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/03/21	2014/10/16	rogid:7kwsm9SZO70EBVpV0lNGNo6zxeE9606	rogid:ZSaEOpu8SYAilgfYzcK/EGgUoiI9606	intact-crc:612739794488CCB6|rigid:AKC2z8jyihwJhekBNn4X53oZeJs	false	-	tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)