#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q92956 uniprotkb:Q13077 intact:EBI-1056653|uniprotkb:Q6IB95|uniprotkb:Q8WXR1|uniprotkb:Q96J31|uniprotkb:Q9UM65|uniprotkb:B9DI89|uniprotkb:B3KW30|uniprotkb:Q8N634|ensembl:ENSP00000347948|ensembl:ENSP00000478308 intact:EBI-359224|uniprotkb:Q658U1|uniprotkb:Q8NF13|uniprotkb:B4DJ77|ensembl:ENSP00000362994|ensembl:ENSP00000443183 psi-mi:tnr14_human(display_long)|uniprotkb:TNFRSF14(gene name)|psi-mi:TNFRSF14(display_short)|uniprotkb:HVEA(gene name synonym)|uniprotkb:HVEM(gene name synonym)|uniprotkb:UNQ329/PRO509(orf name)|uniprotkb:Herpes virus entry mediator A(gene name synonym)|uniprotkb:Tumor necrosis factor receptor-like 2(gene name synonym) psi-mi:traf1_human(display_long)|uniprotkb:TRAF1(gene name)|psi-mi:TRAF1(display_short)|uniprotkb:EBI6(gene name synonym)|uniprotkb:Epstein-Barr virus-induced protein 6(gene name synonym) psi-mi:"MI:0096"(pull down) Marsters et al. (1997) pubmed:9162022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-523424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003811.2|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019955"(cytokine binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1905675"(negative regulation of adaptive immune memory response)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022332|interpro:IPR034031|rcsb pdb:1JMA|rcsb pdb:2AW2|rcsb pdb:4FHQ|rcsb pdb:4RSU|rcsb pdb:5T2Q|rcsb pdb:6NG3|reactome:R-HSA-388841|reactome:R-HSA-5669034|rcsb pdb:5T2R|ensembl:ENSG00000157873(gene)|ensembl:ENSG00000273936(gene)|ensembl:ENST00000355716(transcript)|ensembl:ENST00000621877(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|refseq:XP_016858209.1|dip:DIP-34779N refseq:NP_001177874.1|refseq:NP_001177876.1|refseq:NP_005649.1|dip:DIP-27514N|ensembl:ENSG00000056558(gene)|ensembl:ENST00000373887(transcript)|ensembl:ENST00000540010(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR027136|interpro:IPR032070|interpro:IPR037306|interpro:IPR043211|mint:Q13077|rcsb pdb:3M0D|rcsb pdb:5E1T|rcsb pdb:5H10|reactome:R-HSA-5357905|reactome:R-HSA-5357956 - - - comment:The authors state that the cytoplasmic domain of HEVM was used in this study but do not indicate which residues were included in the construct.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/03/24 2014/10/16 rogid:h0mNlFr7weiZLHYvGJofgj86y249606 rogid:D51RV1gTNQQjGP978+uv98Hd3Lc9606 intact-crc:AC9103E989BC1564|rigid:FXafqXbko053I2auDjzGZcMH8tM false glutathione s tranferase tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92956 uniprotkb:Q13114 intact:EBI-1056653|uniprotkb:Q6IB95|uniprotkb:Q8WXR1|uniprotkb:Q96J31|uniprotkb:Q9UM65|uniprotkb:B9DI89|uniprotkb:B3KW30|uniprotkb:Q8N634|ensembl:ENSP00000347948|ensembl:ENSP00000478308 intact:EBI-357631|uniprotkb:Q12990|uniprotkb:Q13076|uniprotkb:Q13947|uniprotkb:Q6AZX1|uniprotkb:Q9UNL1|ensembl:ENSP00000376500|ensembl:ENSP00000454207|uniprotkb:B7Z8C4 psi-mi:tnr14_human(display_long)|uniprotkb:TNFRSF14(gene name)|psi-mi:TNFRSF14(display_short)|uniprotkb:HVEA(gene name synonym)|uniprotkb:HVEM(gene name synonym)|uniprotkb:UNQ329/PRO509(orf name)|uniprotkb:Herpes virus entry mediator A(gene name synonym)|uniprotkb:Tumor necrosis factor receptor-like 2(gene name synonym) psi-mi:traf3_human(display_long)|uniprotkb:TRAF3(gene name)|psi-mi:TRAF3(display_short)|uniprotkb:CAP1(gene name synonym)|uniprotkb:CRAF1(gene name synonym)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:CD40-binding protein(gene name synonym)|uniprotkb:LMP1-associated protein 1(gene name synonym)|uniprotkb:CAP-1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym) psi-mi:"MI:0096"(pull down) Marsters et al. (1997) pubmed:9162022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-523454 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003811.2|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019955"(cytokine binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1905675"(negative regulation of adaptive immune memory response)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022332|interpro:IPR034031|rcsb pdb:1JMA|rcsb pdb:2AW2|rcsb pdb:4FHQ|rcsb pdb:4RSU|rcsb pdb:5T2Q|rcsb pdb:6NG3|reactome:R-HSA-388841|reactome:R-HSA-5669034|rcsb pdb:5T2R|ensembl:ENSG00000157873(gene)|ensembl:ENSG00000273936(gene)|ensembl:ENST00000355716(transcript)|ensembl:ENST00000621877(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|refseq:XP_016858209.1|dip:DIP-34779N ensembl:ENSG00000131323(gene)|ensembl:ENST00000392745(transcript)|ensembl:ENST00000560371(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|refseq:NP_001186356.1|refseq:NP_003291.2|refseq:NP_663777.1|refseq:NP_663778.1|go:"GO:0007165"(signal transduction)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q13114|go:"GO:0042981"(regulation of apoptotic process)|rcsb pdb:1FLK|rcsb pdb:1FLL|rcsb pdb:1L0A|rcsb pdb:1RF3|rcsb pdb:1ZMS|rcsb pdb:2ECY|rcsb pdb:2GKW|rcsb pdb:1KZZ|refseq:XP_011535420.1|reactome:R-HSA-5668541|reactome:R-HSA-5676594|reactome:R-HSA-5689896|reactome:R-HSA-9013973|reactome:R-HSA-918233|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-5602571|refseq:XP_016877106.1|refseq:XP_016877107.1|dip:DIP-6222N - - - comment:The authors state that the cytoplasmic domain of HEVM was used in this study but do not indicate which residues were included in the construct.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/03/24 2014/10/16 rogid:h0mNlFr7weiZLHYvGJofgj86y249606 rogid:9Tjx/USypDBBrPVyFOsLzM/bwzA9606 intact-crc:0FE6ADB28F4A7A27|rigid:HDYgI3ISVk9r6ZJsPIWlGIEdem0 false glutathione s tranferase tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00463 uniprotkb:Q92956 intact:EBI-523498|ensembl:ENSP00000261464|ensembl:ENSP00000336825|ensembl:ENSP00000355971|uniprotkb:Q6FHY1|uniprotkb:B4DIS9|uniprotkb:B4E0A2 intact:EBI-1056653|uniprotkb:Q6IB95|uniprotkb:Q8WXR1|uniprotkb:Q96J31|uniprotkb:Q9UM65|uniprotkb:B9DI89|uniprotkb:B3KW30|uniprotkb:Q8N634|ensembl:ENSP00000347948|ensembl:ENSP00000478308 psi-mi:traf5_human(display_long)|uniprotkb:RING finger protein 84(gene name synonym)|uniprotkb:TRAF5(gene name)|psi-mi:TRAF5(display_short)|uniprotkb:RNF84(gene name synonym) psi-mi:tnr14_human(display_long)|uniprotkb:TNFRSF14(gene name)|psi-mi:TNFRSF14(display_short)|uniprotkb:HVEA(gene name synonym)|uniprotkb:HVEM(gene name synonym)|uniprotkb:UNQ329/PRO509(orf name)|uniprotkb:Herpes virus entry mediator A(gene name synonym)|uniprotkb:Tumor necrosis factor receptor-like 2(gene name synonym) psi-mi:"MI:0096"(pull down) Marsters et al. (1997) pubmed:9162022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-523474 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001306136.1|refseq:XP_011508261.1|refseq:XP_011508262.1|ensembl:ENSG00000082512(gene)|ensembl:ENST00000261464(transcript)|ensembl:ENST00000336184(transcript)|ensembl:ENST00000367004(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR027130|interpro:IPR043211|mint:O00463|rcsb pdb:7L3L|refseq:NP_001029082.1|refseq:NP_004610.1|refseq:NP_665702.1|refseq:XP_016857710.1 refseq:NP_003811.2|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019955"(cytokine binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1905675"(negative regulation of adaptive immune memory response)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022332|interpro:IPR034031|rcsb pdb:1JMA|rcsb pdb:2AW2|rcsb pdb:4FHQ|rcsb pdb:4RSU|rcsb pdb:5T2Q|rcsb pdb:6NG3|reactome:R-HSA-388841|reactome:R-HSA-5669034|rcsb pdb:5T2R|ensembl:ENSG00000157873(gene)|ensembl:ENSG00000273936(gene)|ensembl:ENST00000355716(transcript)|ensembl:ENST00000621877(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|refseq:XP_016858209.1|dip:DIP-34779N - - - comment:The authors state that the cytoplasmic domain of HEVM was used in this study but do not indicate which residues were included in the construct.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/03/24 2014/10/16 rogid:xPAQGevMJLEAPcT6eX3n304eSOw9606 rogid:h0mNlFr7weiZLHYvGJofgj86y249606 intact-crc:EB40418F278E897B|rigid:CB/Gof0wQot2bsXmUyAXiY5XPXc false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12933-2 uniprotkb:Q92956 intact:EBI-355760 intact:EBI-1056653|uniprotkb:Q6IB95|uniprotkb:Q8WXR1|uniprotkb:Q96J31|uniprotkb:Q9UM65|uniprotkb:B9DI89|uniprotkb:B3KW30|uniprotkb:Q8N634|ensembl:ENSP00000347948|ensembl:ENSP00000478308 psi-mi:q12933-2(display_long)|uniprotkb:TRAF2(gene name)|psi-mi:TRAF2(display_short)|uniprotkb:TRAP3(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF2(gene name synonym)|uniprotkb:Tumor necrosis factor type 2 receptor-associated protein 3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF2(gene name synonym) psi-mi:tnr14_human(display_long)|uniprotkb:TNFRSF14(gene name)|psi-mi:TNFRSF14(display_short)|uniprotkb:HVEA(gene name synonym)|uniprotkb:HVEM(gene name synonym)|uniprotkb:UNQ329/PRO509(orf name)|uniprotkb:Herpes virus entry mediator A(gene name synonym)|uniprotkb:Tumor necrosis factor receptor-like 2(gene name synonym) psi-mi:"MI:0096"(pull down) Marsters et al. (1997) pubmed:9162022 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-523531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-355744(traf2_human)|uniprotkb:Q12933-2(isoform-parent) refseq:NP_003811.2|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019955"(cytokine binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:1905675"(negative regulation of adaptive immune memory response)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR022332|interpro:IPR034031|rcsb pdb:1JMA|rcsb pdb:2AW2|rcsb pdb:4FHQ|rcsb pdb:4RSU|rcsb pdb:5T2Q|rcsb pdb:6NG3|reactome:R-HSA-388841|reactome:R-HSA-5669034|rcsb pdb:5T2R|ensembl:ENSG00000157873(gene)|ensembl:ENSG00000273936(gene)|ensembl:ENST00000355716(transcript)|ensembl:ENST00000621877(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|refseq:XP_016858209.1|dip:DIP-34779N - isoform-comment:No experimental confirmation available. - comment:The authors state that the cytoplasmic domain of HEVM was used in this study but do not indicate which residues were included in the construct.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/03/24 2014/10/16 rogid:R7gJwK3F/EZDSTpNCjl+ZCjrUXg9606 rogid:h0mNlFr7weiZLHYvGJofgj86y249606 intact-crc:16BD081439CDFF30|rigid:0cN2MMgNcTY0X7PxHbkJ6aew4Qk false flag tag:?-? glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)