#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P26793	uniprotkb:P15873	intact:EBI-14693|uniprotkb:D6VXH5|ensemblfungi:YKL113C	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	psi-mi:fen1_yeast(display_long)|uniprotkb:RAD27(gene name)|psi-mi:RAD27(display_short)|uniprotkb:RTH1(gene name synonym)|uniprotkb:YKL113C(locus name)|uniprotkb:YKL510(orf name)|uniprotkb:FEN1(gene name synonym)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:RAD2 homolog nuclease 1(gene name synonym)|uniprotkb:Structure-specific endonuclease RAD27(gene name synonym)	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:"MI:0004"(affinity chromatography technology)	Li et al. (1995)	pubmed:7673186|mint:MINT-5220513	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-707890	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012809.1|sgd:S000001596|ensemblfungi:YKL113C(gene)|ensemblfungi:YKL113C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043137"(DNA replication, removal of RNA primer)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|reactome:R-SCE-69166|dip:DIP-2325N|mint:P26793	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L	-	crc64:1F54B08720121C8C	crc64:9B56C5851621DDDC	comment:both proteins are purified	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/10	2014/10/16	rogid:bUkyl5asIehXbNz6Hjt7TAyCT5o559292	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	intact-crc:32757E80A6305EBB|rigid:OKCxFbBEbelK33Y97qsKPb1YiI8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15873	uniprotkb:P26793	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	intact:EBI-14693|uniprotkb:D6VXH5|ensemblfungi:YKL113C	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:fen1_yeast(display_long)|uniprotkb:RAD27(gene name)|psi-mi:RAD27(display_short)|uniprotkb:RTH1(gene name synonym)|uniprotkb:YKL113C(locus name)|uniprotkb:YKL510(orf name)|uniprotkb:FEN1(gene name synonym)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:RAD2 homolog nuclease 1(gene name synonym)|uniprotkb:Structure-specific endonuclease RAD27(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Li et al. (1995)	pubmed:7673186|mint:MINT-5220513	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-707896	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L	refseq:NP_012809.1|sgd:S000001596|ensemblfungi:YKL113C(gene)|ensemblfungi:YKL113C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043137"(DNA replication, removal of RNA primer)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|reactome:R-SCE-69166|dip:DIP-2325N|mint:P26793	-	crc64:9B56C5851621DDDC	crc64:1F54B08720121C8C	comment:"FEN-1 (rad27) was sreened from a yeast crude lysate"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/11/10	2014/10/16	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	rogid:bUkyl5asIehXbNz6Hjt7TAyCT5o559292	intact-crc:07E8479061133C20|rigid:OKCxFbBEbelK33Y97qsKPb1YiI8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P26793	uniprotkb:P15873	intact:EBI-14693|uniprotkb:D6VXH5|ensemblfungi:YKL113C	intact:EBI-12993|uniprotkb:D6VQ89|ensemblfungi:YBR088C	psi-mi:fen1_yeast(display_long)|uniprotkb:RAD27(gene name)|psi-mi:RAD27(display_short)|uniprotkb:RTH1(gene name synonym)|uniprotkb:YKL113C(locus name)|uniprotkb:YKL510(orf name)|uniprotkb:FEN1(gene name synonym)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:RAD2 homolog nuclease 1(gene name synonym)|uniprotkb:Structure-specific endonuclease RAD27(gene name synonym)	psi-mi:pcna_yeast(display_long)|uniprotkb:YBR0811(orf name)|uniprotkb:YBR088C(locus name)|uniprotkb:POL30(gene name)|psi-mi:POL30(display_short)	psi-mi:"MI:0018"(two hybrid)	Li et al. (1995)	pubmed:7673186|mint:MINT-5220513	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-707903	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012809.1|sgd:S000001596|ensemblfungi:YKL113C(gene)|ensemblfungi:YKL113C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006286"(obsolete base-excision repair, base-free sugar-phosphate removal)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0043137"(DNA replication, removal of RNA primer)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|reactome:R-SCE-69166|dip:DIP-2325N|mint:P26793	refseq:NP_009645.1|sgd:S000000292|go:"GO:0043626"(PCNA complex)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:1902394"(positive regulation of exodeoxyribonuclease activity)|go:"GO:1903022"(positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands)|go:"GO:1905779"(positive regulation of exonuclease activity)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|rcsb pdb:1PLQ|rcsb pdb:1PLR|rcsb pdb:1SXJ|rcsb pdb:2OD8|rcsb pdb:3F1W|rcsb pdb:3GPM|rcsb pdb:3GPN|rcsb pdb:3L0W|rcsb pdb:4L6P|rcsb pdb:3L0X|rcsb pdb:3L10|rcsb pdb:4YHR|rcsb pdb:3PGE|rcsb pdb:3V60|rcsb pdb:3V61|rcsb pdb:3V62|rcsb pdb:5JNE|rcsb pdb:4L60|mint:P15873|dip:DIP-2417N|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|ensemblfungi:YBR088C(gene)|ensemblfungi:YBR088C_mRNA(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006348"|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0042802"(identical protein binding)|rcsb pdb:5T9D|rcsb pdb:5V7K|rcsb pdb:5V7M|rcsb pdb:5ZUT|rcsb pdb:6CX2|rcsb pdb:6CX3|rcsb pdb:6CX4|rcsb pdb:6D0Q|rcsb pdb:6D0R|rcsb pdb:6E49|rcsb pdb:6W9W|rcsb pdb:6WAC|reactome:R-SCE-110312|reactome:R-SCE-110320|reactome:R-SCE-4615885|reactome:R-SCE-5358565|reactome:R-SCE-5655862|reactome:R-SCE-5656121|reactome:R-SCE-5656169|reactome:R-SCE-6782135|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183|reactome:R-SCE-8866654|rcsb pdb:5V7L	-	crc64:1F54B08720121C8C	crc64:9B56C5851621DDDC	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2005/11/10	2014/10/16	rogid:bUkyl5asIehXbNz6Hjt7TAyCT5o559292	rogid:/+XSPV99OBBwBBC/nY0JiHaAeSI559292	intact-crc:3560A06B7A48B01C|rigid:OKCxFbBEbelK33Y97qsKPb1YiI8	false	sufficient binding region:81-382..382	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)