#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P35269 uniprotkb:P21675 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3 psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ruppert et al. (1995) pubmed:7590250 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-515106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606 intact-crc:B40EBD1A93418668|rigid:oTKGhivWZrdly7MEz6rpF8IWXyE false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P21675 uniprotkb:P35269 intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym) psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ruppert et al. (1995) pubmed:7590250 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-515162 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 intact-crc:E12E844019179FF5|rigid:oTKGhivWZrdly7MEz6rpF8IWXyE false ha tag:?-? - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P21675 uniprotkb:P35269 intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym) psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ruppert et al. (1995) pubmed:7590250 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-515429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N - - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/04 2014/10/16 rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 intact-crc:48ABE9AF9DD1BA22|rigid:oTKGhivWZrdly7MEz6rpF8IWXyE false binding-associated region:1-120|ha tag:?-? radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)