#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13688 uniprotkb:Q9H2X3 intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559 intact:EBI-1391211|uniprotkb:Q69F40|uniprotkb:Q969M4|uniprotkb:Q96QP3|uniprotkb:Q96QP4|uniprotkb:Q96QP5|uniprotkb:Q96QP6|uniprotkb:Q9BXS3|uniprotkb:Q9H2Q9|uniprotkb:Q9H8F0|uniprotkb:Q9Y2A8|uniprotkb:A6NKI4|uniprotkb:A8K8B3|ensembl:ENSP00000316228 psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym) psi-mi:clc4m_human(display_long)|uniprotkb:CD209 antigen-like protein 1(gene name synonym)|uniprotkb:Dendritic cell-specific ICAM-3-grabbing non-integrin 2(gene name synonym)|uniprotkb:DC-SIGN-related protein(gene name synonym)|uniprotkb:Liver/lymph node-specific ICAM-3-grabbing non-integrin(gene name synonym)|uniprotkb:CLEC4M(gene name)|psi-mi:CLEC4M(display_short)|uniprotkb:CD209L(gene name synonym)|uniprotkb:CD209L1(gene name synonym)|uniprotkb:CD299(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) van et al. (2005) pubmed:16246332|imex:IM-11403|mint:MINT-5218034 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7858660|mint:MINT-72821|imex:IM-11403-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|go:"GO:0031528"(microvillus membrane)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0038158"(granulocyte colony-stimulating factor signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043318"(negative regulation of cytotoxic T cell degranulation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045601"(regulation of endothelial cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0031005"(filamin binding)|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-1566977|refseq:XP_011525508.1|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903385"(regulation of homophilic cell adhesion)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000346"(negative regulation of hepatocyte proliferation)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|ensembl:ENSG00000079385(gene)|ensembl:ENST00000161559(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0002859"(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|dip:DIP-42683N|mint:MINT-1489324(identity) refseq:XP_006722678.1|refseq:NP_001138377.1|refseq:NP_001138378.1|refseq:NP_001138379.1|refseq:NP_001138380.1|refseq:NP_001138381.1|refseq:NP_001138382.1|refseq:NP_001138383.1|refseq:NP_055072.3|ensembl:ENSG00000104938(gene)|ensembl:ENST00000327325(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009988"(cell-cell recognition)|go:"GO:0016020"(membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019079"(viral genome replication)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043657"(host cell)|go:"GO:0045087"(innate immune response)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|rcsb pdb:1K9J|rcsb pdb:1SL6|rcsb pdb:1XAR|rcsb pdb:1XPH|rcsb pdb:1Z0Y|rcsb pdb:3JQH|mint:MINT-1489329(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/29 2014/10/16 rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606 rogid:FR9EEv0vaGUvH/qu0Hg6gLa0yOw9606 intact-crc:16E9FFC47035818D|rigid:9ZnaTDBpVqZTa62nG/lkC9gTyVc false - binding-associated region:60-399(MINT-1489330) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q9H2X3 uniprotkb:P11215 intact:EBI-1391211|uniprotkb:Q69F40|uniprotkb:Q969M4|uniprotkb:Q96QP3|uniprotkb:Q96QP4|uniprotkb:Q96QP5|uniprotkb:Q96QP6|uniprotkb:Q9BXS3|uniprotkb:Q9H2Q9|uniprotkb:Q9H8F0|uniprotkb:Q9Y2A8|uniprotkb:A6NKI4|uniprotkb:A8K8B3|ensembl:ENSP00000316228 intact:EBI-2568251|uniprotkb:Q4VAK0|uniprotkb:Q4VAK2|ensembl:ENSP00000441691|uniprotkb:Q4VAK1 psi-mi:clc4m_human(display_long)|uniprotkb:CD209 antigen-like protein 1(gene name synonym)|uniprotkb:Dendritic cell-specific ICAM-3-grabbing non-integrin 2(gene name synonym)|uniprotkb:DC-SIGN-related protein(gene name synonym)|uniprotkb:Liver/lymph node-specific ICAM-3-grabbing non-integrin(gene name synonym)|uniprotkb:CLEC4M(gene name)|psi-mi:CLEC4M(display_short)|uniprotkb:CD209L(gene name synonym)|uniprotkb:CD209L1(gene name synonym)|uniprotkb:CD299(gene name synonym) psi-mi:itam_human(display_long)|uniprotkb:ITGAM(gene name)|psi-mi:ITGAM(display_short)|uniprotkb:CD11B(gene name synonym)|uniprotkb:CR3A(gene name synonym)|uniprotkb:Cell surface glycoprotein MAC-1 subunit alpha(gene name synonym)|uniprotkb:CR-3 alpha chain(gene name synonym)|uniprotkb:Leukocyte adhesion receptor MO1(gene name synonym)|uniprotkb:Neutrophil adherence receptor(gene name synonym)|uniprotkb:CD11 antigen-like family member B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) van et al. (2005) pubmed:16246332|imex:IM-11403|mint:MINT-5218034 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7858696|mint:MINT-72823|imex:IM-11403-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006722678.1|refseq:NP_001138377.1|refseq:NP_001138378.1|refseq:NP_001138379.1|refseq:NP_001138380.1|refseq:NP_001138381.1|refseq:NP_001138382.1|refseq:NP_001138383.1|refseq:NP_055072.3|ensembl:ENSG00000104938(gene)|ensembl:ENST00000327325(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009988"(cell-cell recognition)|go:"GO:0016020"(membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019079"(viral genome replication)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043657"(host cell)|go:"GO:0045087"(innate immune response)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|rcsb pdb:1K9J|rcsb pdb:1SL6|rcsb pdb:1XAR|rcsb pdb:1XPH|rcsb pdb:1Z0Y|rcsb pdb:3JQH|mint:MINT-1489346(identity) refseq:NP_000623.2|refseq:NP_001139280.1|ensembl:ENSG00000169896(gene)|ensembl:ENST00000544665(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045087"(innate immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|rcsb pdb:1A8X|rcsb pdb:1BHO|rcsb pdb:1BHQ|rcsb pdb:1IDN|rcsb pdb:1IDO|rcsb pdb:1JLM|rcsb pdb:1M1U|rcsb pdb:1MF7|rcsb pdb:1N9Z|rcsb pdb:1NA5|rcsb pdb:2LKE|rcsb pdb:2LKJ|rcsb pdb:3Q3G|rcsb pdb:3QA3|rcsb pdb:4M76|rcsb pdb:4XW2|rcsb pdb:6RHW|reactome:R-HSA-166016|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|mint:MINT-1489341(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/29 2014/10/16 rogid:FR9EEv0vaGUvH/qu0Hg6gLa0yOw9606 rogid:LdazC8w25LRfb+vgr/kGcKmIkYo9606 intact-crc:FEA20E6671F4BD22|rigid:wxpfOl/N3nfauvZr2GEmLDueOR4 false binding-associated region:60-399(MINT-1489347) - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P13688 uniprotkb:Q9H2X3 intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559 intact:EBI-1391211|uniprotkb:Q69F40|uniprotkb:Q969M4|uniprotkb:Q96QP3|uniprotkb:Q96QP4|uniprotkb:Q96QP5|uniprotkb:Q96QP6|uniprotkb:Q9BXS3|uniprotkb:Q9H2Q9|uniprotkb:Q9H8F0|uniprotkb:Q9Y2A8|uniprotkb:A6NKI4|uniprotkb:A8K8B3|ensembl:ENSP00000316228 psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym) psi-mi:clc4m_human(display_long)|uniprotkb:CD209 antigen-like protein 1(gene name synonym)|uniprotkb:Dendritic cell-specific ICAM-3-grabbing non-integrin 2(gene name synonym)|uniprotkb:DC-SIGN-related protein(gene name synonym)|uniprotkb:Liver/lymph node-specific ICAM-3-grabbing non-integrin(gene name synonym)|uniprotkb:CLEC4M(gene name)|psi-mi:CLEC4M(display_short)|uniprotkb:CD209L(gene name synonym)|uniprotkb:CD209L1(gene name synonym)|uniprotkb:CD299(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) van et al. (2005) pubmed:16246332|imex:IM-11403|mint:MINT-5218034 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7858770|mint:MINT-72826|imex:IM-11403-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|go:"GO:0031528"(microvillus membrane)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0038158"(granulocyte colony-stimulating factor signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043318"(negative regulation of cytotoxic T cell degranulation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045601"(regulation of endothelial cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0031005"(filamin binding)|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-1566977|refseq:XP_011525508.1|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903385"(regulation of homophilic cell adhesion)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000346"(negative regulation of hepatocyte proliferation)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|ensembl:ENSG00000079385(gene)|ensembl:ENST00000161559(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0002859"(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|dip:DIP-42683N|mint:MINT-1489241(identity) refseq:XP_006722678.1|refseq:NP_001138377.1|refseq:NP_001138378.1|refseq:NP_001138379.1|refseq:NP_001138380.1|refseq:NP_001138381.1|refseq:NP_001138382.1|refseq:NP_001138383.1|refseq:NP_055072.3|ensembl:ENSG00000104938(gene)|ensembl:ENST00000327325(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009988"(cell-cell recognition)|go:"GO:0016020"(membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019079"(viral genome replication)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043657"(host cell)|go:"GO:0045087"(innate immune response)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|rcsb pdb:1K9J|rcsb pdb:1SL6|rcsb pdb:1XAR|rcsb pdb:1XPH|rcsb pdb:1Z0Y|rcsb pdb:3JQH|mint:MINT-1489246(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/29 2014/10/16 rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606 rogid:FR9EEv0vaGUvH/qu0Hg6gLa0yOw9606 intact-crc:EBA11C42F54740F7|rigid:9ZnaTDBpVqZTa62nG/lkC9gTyVc false - binding-associated region:60-399(MINT-1489247) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P11215 uniprotkb:Q9H2X3 intact:EBI-2568251|uniprotkb:Q4VAK0|uniprotkb:Q4VAK2|ensembl:ENSP00000441691|uniprotkb:Q4VAK1 intact:EBI-1391211|uniprotkb:Q69F40|uniprotkb:Q969M4|uniprotkb:Q96QP3|uniprotkb:Q96QP4|uniprotkb:Q96QP5|uniprotkb:Q96QP6|uniprotkb:Q9BXS3|uniprotkb:Q9H2Q9|uniprotkb:Q9H8F0|uniprotkb:Q9Y2A8|uniprotkb:A6NKI4|uniprotkb:A8K8B3|ensembl:ENSP00000316228 psi-mi:itam_human(display_long)|uniprotkb:ITGAM(gene name)|psi-mi:ITGAM(display_short)|uniprotkb:CD11B(gene name synonym)|uniprotkb:CR3A(gene name synonym)|uniprotkb:Cell surface glycoprotein MAC-1 subunit alpha(gene name synonym)|uniprotkb:CR-3 alpha chain(gene name synonym)|uniprotkb:Leukocyte adhesion receptor MO1(gene name synonym)|uniprotkb:Neutrophil adherence receptor(gene name synonym)|uniprotkb:CD11 antigen-like family member B(gene name synonym) psi-mi:clc4m_human(display_long)|uniprotkb:CD209 antigen-like protein 1(gene name synonym)|uniprotkb:Dendritic cell-specific ICAM-3-grabbing non-integrin 2(gene name synonym)|uniprotkb:DC-SIGN-related protein(gene name synonym)|uniprotkb:Liver/lymph node-specific ICAM-3-grabbing non-integrin(gene name synonym)|uniprotkb:CLEC4M(gene name)|psi-mi:CLEC4M(display_short)|uniprotkb:CD209L(gene name synonym)|uniprotkb:CD209L1(gene name synonym)|uniprotkb:CD299(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) van et al. (2005) pubmed:16246332|imex:IM-11403|mint:MINT-5218034 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7858733|mint:MINT-72825|imex:IM-11403-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000623.2|refseq:NP_001139280.1|ensembl:ENSG00000169896(gene)|ensembl:ENST00000544665(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045087"(innate immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|rcsb pdb:1A8X|rcsb pdb:1BHO|rcsb pdb:1BHQ|rcsb pdb:1IDN|rcsb pdb:1IDO|rcsb pdb:1JLM|rcsb pdb:1M1U|rcsb pdb:1MF7|rcsb pdb:1N9Z|rcsb pdb:1NA5|rcsb pdb:2LKE|rcsb pdb:2LKJ|rcsb pdb:3Q3G|rcsb pdb:3QA3|rcsb pdb:4M76|rcsb pdb:4XW2|rcsb pdb:6RHW|reactome:R-HSA-166016|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|mint:MINT-1489307(identity) refseq:XP_006722678.1|refseq:NP_001138377.1|refseq:NP_001138378.1|refseq:NP_001138379.1|refseq:NP_001138380.1|refseq:NP_001138381.1|refseq:NP_001138382.1|refseq:NP_001138383.1|refseq:NP_055072.3|ensembl:ENSG00000104938(gene)|ensembl:ENST00000327325(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005537"(mannose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0009988"(cell-cell recognition)|go:"GO:0016020"(membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019079"(viral genome replication)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0043657"(host cell)|go:"GO:0045087"(innate immune response)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046968"(peptide antigen transport)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0075733"(intracellular transport of virus)|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR018378|interpro:IPR033989|rcsb pdb:1K9J|rcsb pdb:1SL6|rcsb pdb:1XAR|rcsb pdb:1XPH|rcsb pdb:1Z0Y|rcsb pdb:3JQH|mint:MINT-1489312(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/11/29 2014/10/16 rogid:LdazC8w25LRfb+vgr/kGcKmIkYo9606 rogid:FR9EEv0vaGUvH/qu0Hg6gLa0yOw9606 intact-crc:73F293A3F12CBC1F|rigid:wxpfOl/N3nfauvZr2GEmLDueOR4 false - binding-associated region:60-399(MINT-1489313) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)