#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06240	uniprotkb:Q63767	intact:EBI-1401|ensembl:ENSMUSP00000066209|ensembl:ENSMUSP00000099656|uniprotkb:Q62320|uniprotkb:Q61795|uniprotkb:Q61794|uniprotkb:Q91X65	intact:EBI-1176801|uniprotkb:Q63766	psi-mi:lck_mouse(display_long)|uniprotkb:Lck(gene name)|psi-mi:Lck(display_short)|uniprotkb:Lsk-t(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856247|mint:MINT-68711	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000409(gene)|ensembl:ENSMUST00000067240(transcript)|ensembl:ENSMUST00000102596(transcript)|go:"GO:0000242"(pericentriolar material)|refseq:NP_001155905.1|refseq:NP_034823.1|refseq:XP_006502881.1|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010038"(response to metal ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-6811558|reactome:R-MMU-9013407|reactome:R-MMU-9020558|reactome:R-MMU-9706374|mint:MINT-1488967(identity)	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-1488976(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/31	2014/10/16	rogid:yjMU0fxTseBSR5/aEXmp2cR7Mts10090	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	intact-crc:D89181116FE172F0|rigid:nhy9YosZ3Apu8k2ZePAL7TEJCCs	false	binding-associated region:64-226(MINT-1488968)	binding-associated region:759-767(MINT-1488977)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9WUD9	uniprotkb:Q63767	intact:EBI-7784541|ensembl:ENSRNOP00000012739|intact:MINT-1488989|intact:EBI-8633267|intact:MINT-264632|uniprotkb:G3V776|uniprotkb:Q45QJ2|uniprotkb:Q9JJ10	intact:EBI-1176801|uniprotkb:Q63766	psi-mi:src_rat(display_long)|uniprotkb:Src(gene name)|psi-mi:Src(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856282|mint:MINT-68709	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008760609.1|refseq:XP_008760610.1|ensembl:ENSRNOG00000009495(gene)|ensembl:ENSRNOT00000012739(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0005884"(actin filament)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|refseq:XP_017447554.1|refseq:XP_017447555.1|refseq:XP_017447556.1|refseq:XP_017447557.1|refseq:XP_017447558.1|refseq:XP_017447559.1|refseq:XP_017447560.1|refseq:XP_017447561.1|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070542"(response to fatty acid)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:Q9WUD9|reactome:R-RNO-1227986|reactome:R-RNO-1251985|reactome:R-RNO-1253288|reactome:R-RNO-1257604|reactome:R-RNO-1295596|reactome:R-RNO-1433557|reactome:R-RNO-1433559|reactome:R-RNO-177929|reactome:R-RNO-180292|reactome:R-RNO-186763|reactome:R-RNO-191650|reactome:R-RNO-2029481|reactome:R-RNO-210990|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-389356|reactome:R-RNO-389513|reactome:R-RNO-3928662|reactome:R-RNO-3928663|reactome:R-RNO-3928664|reactome:R-RNO-3928665|reactome:R-RNO-418592|reactome:R-RNO-418594|reactome:R-RNO-418885|reactome:R-RNO-430116|reactome:R-RNO-437239|reactome:R-RNO-4420097|reactome:R-RNO-456926|reactome:R-RNO-5218921|reactome:R-RNO-5607764|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-6811558|reactome:R-RNO-69231|reactome:R-RNO-8853659|reactome:R-RNO-8874081|reactome:R-RNO-8934903|reactome:R-RNO-8941858|reactome:R-RNO-9603381|reactome:R-RNO-9009391|refseq:NP_114183.1|rgd:620795|dip:DIP-42731N	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-1489010(identity)	-	comment:mint|comment:homomint	comment:"Stoichiometry: 1.0"	figure legend:F3A|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/31	2014/10/16	rogid:nxU40GY4yiVLT+BMi6GuF5YETGA10116	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	intact-crc:978E7A23FF79740E|rigid:9U65Lht9HvLxiYw1ty4EA9RumXQ	false	binding-associated region:143-266|glutathione s tranferase tag:?-?	O4'-phospho-L-tyrosine:?-?(MINT-1489014)|binding-associated region:548-812(MINT-1489011)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P06240	uniprotkb:Q63767	intact:EBI-1401|ensembl:ENSMUSP00000066209|ensembl:ENSMUSP00000099656|uniprotkb:Q62320|uniprotkb:Q61795|uniprotkb:Q61794|uniprotkb:Q91X65	intact:EBI-1176801|uniprotkb:Q63766	psi-mi:lck_mouse(display_long)|uniprotkb:Lck(gene name)|psi-mi:Lck(display_short)|uniprotkb:Lsk-t(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856310|mint:MINT-68710	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000409(gene)|ensembl:ENSMUST00000067240(transcript)|ensembl:ENSMUST00000102596(transcript)|go:"GO:0000242"(pericentriolar material)|refseq:NP_001155905.1|refseq:NP_034823.1|refseq:XP_006502881.1|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010038"(response to metal ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-6811558|reactome:R-MMU-9013407|reactome:R-MMU-9020558|reactome:R-MMU-9706374|mint:MINT-1489022(identity)	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-1489033(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3B|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/31	2014/10/16	rogid:yjMU0fxTseBSR5/aEXmp2cR7Mts10090	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	intact-crc:797CAE2EB70E03C1|rigid:nhy9YosZ3Apu8k2ZePAL7TEJCCs	false	his tag:?-?(MINT-1489027)|binding-associated region:64-226(IPR000980)	O4'-phospho-L-tyrosine:?-?(MINT-1489037)|binding-associated region:548-812(MINT-1489034)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9WUD9	uniprotkb:Q63767	intact:EBI-7784541|ensembl:ENSRNOP00000012739|intact:MINT-1488989|intact:EBI-8633267|intact:MINT-264632|uniprotkb:G3V776|uniprotkb:Q45QJ2|uniprotkb:Q9JJ10	intact:EBI-1176801|uniprotkb:Q63766	psi-mi:src_rat(display_long)|uniprotkb:Src(gene name)|psi-mi:Src(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856351|mint:MINT-68708	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_008760609.1|refseq:XP_008760610.1|ensembl:ENSRNOG00000009495(gene)|ensembl:ENSRNOT00000012739(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0005884"(actin filament)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010641"(positive regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|refseq:XP_017447554.1|refseq:XP_017447555.1|refseq:XP_017447556.1|refseq:XP_017447557.1|refseq:XP_017447558.1|refseq:XP_017447559.1|refseq:XP_017447560.1|refseq:XP_017447561.1|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070542"(response to fatty acid)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:Q9WUD9|reactome:R-RNO-1227986|reactome:R-RNO-1251985|reactome:R-RNO-1253288|reactome:R-RNO-1257604|reactome:R-RNO-1295596|reactome:R-RNO-1433557|reactome:R-RNO-1433559|reactome:R-RNO-177929|reactome:R-RNO-180292|reactome:R-RNO-186763|reactome:R-RNO-191650|reactome:R-RNO-2029481|reactome:R-RNO-210990|reactome:R-RNO-354192|reactome:R-RNO-354194|reactome:R-RNO-372708|reactome:R-RNO-389356|reactome:R-RNO-389513|reactome:R-RNO-3928662|reactome:R-RNO-3928663|reactome:R-RNO-3928664|reactome:R-RNO-3928665|reactome:R-RNO-418592|reactome:R-RNO-418594|reactome:R-RNO-418885|reactome:R-RNO-430116|reactome:R-RNO-437239|reactome:R-RNO-4420097|reactome:R-RNO-456926|reactome:R-RNO-5218921|reactome:R-RNO-5607764|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-6811558|reactome:R-RNO-69231|reactome:R-RNO-8853659|reactome:R-RNO-8874081|reactome:R-RNO-8934903|reactome:R-RNO-8941858|reactome:R-RNO-9603381|reactome:R-RNO-9009391|refseq:NP_114183.1|rgd:620795|dip:DIP-42731N	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-1489057(identity)	-	comment:mint|comment:homomint	comment:"Stoichiometry: 1.0"	figure legend:F2|kd:25-46 nanomolar|comment:homomint|comment:domino|comment:mint|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/31	2014/10/16	rogid:nxU40GY4yiVLT+BMi6GuF5YETGA10116	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	intact-crc:5189B47990D8B22B|rigid:9U65Lht9HvLxiYw1ty4EA9RumXQ	false	glutathione s tranferase tag:?-?|binding-associated region:143-266	binding-associated region:548-812(MINT-1489058)|O4'-phospho-L-tyrosine:?-?(MINT-1489061)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q63767	uniprotkb:P06239	intact:EBI-1176801|uniprotkb:Q63766	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|ensembl:ENSP00000337825|ensembl:ENSP00000477713|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856391|mint:MINT-8030053	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-8030057(identity)|uniprotkb:Q63767(original identifier)	refseq:NP_001036236.1|refseq:NP_005347.3|ensembl:ENSG00000182866(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensembl:ENST00000336890(transcript)|ensembl:ENST00000619559(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|dip:DIP-553N|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051249"(regulation of lymphocyte activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|mint:MINT-8030054(identity)|uniprotkb:P06239(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2005/10/31	2014/10/16	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	intact-crc:7D4B0FE758810BEE|rigid:rLbEebg/AeeytbtPNUWy/G1PFlU	false	binding-associated region:755-768(MINT-8030060)|phosphorylated residue:762-762(MINT-8030062)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06239	uniprotkb:Q63767	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|ensembl:ENSP00000337825|ensembl:ENSP00000477713|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8	intact:EBI-1176801|uniprotkb:Q63766	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856420|mint:MINT-8030068	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001036236.1|refseq:NP_005347.3|ensembl:ENSG00000182866(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensembl:ENST00000336890(transcript)|ensembl:ENST00000619559(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|dip:DIP-553N|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051249"(regulation of lymphocyte activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|mint:MINT-8030069(identity)|uniprotkb:P06239(original identifier)	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-8030072(identity)|uniprotkb:Q63767(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2005/10/31	2014/10/16	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	intact-crc:BF97E5EFC2EED28E|rigid:rLbEebg/AeeytbtPNUWy/G1PFlU	false	-	phosphorylated residue:762-762(MINT-8030077)|binding-associated region:755-768(MINT-8030075)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q63767	uniprotkb:P06239	intact:EBI-1176801|uniprotkb:Q63766	intact:EBI-1348|uniprotkb:P07100|uniprotkb:Q12850|uniprotkb:Q13152|uniprotkb:Q5TDH8|uniprotkb:Q5TDH9|uniprotkb:Q96DW4|uniprotkb:Q9NYT8|ensembl:ENSP00000337825|ensembl:ENSP00000477713|uniprotkb:Q7RTZ3|uniprotkb:D3DPP8	psi-mi:bcar1_rat(display_long)|uniprotkb:CRK-associated substrate(gene name synonym)|uniprotkb:p130cas(gene name synonym)|uniprotkb:Bcar1(gene name)|psi-mi:Bcar1(display_short)|uniprotkb:Cas(gene name synonym)|uniprotkb:Crkas(gene name synonym)	psi-mi:lck_human(display_long)|uniprotkb:Protein YT16(gene name synonym)|uniprotkb:Proto-oncogene Lck(gene name synonym)|uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:LCK(gene name)|psi-mi:LCK(display_short)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Nasertorabi et al. (2006)	pubmed:16245368|mint:MINT-5218030	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7856449|mint:MINT-8030083	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:2406|refseq:NP_037063.1|interpro:IPR021901|interpro:IPR014928(Serine rich protein interaction)|interpro:IPR001452(Src homology-3)|rcsb pdb:1X27|rcsb pdb:1Z23|interpro:IPR037362|go:"GO:0001726"(ruffle)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0050851"(antigen receptor-mediated signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:0008286"(insulin receptor signaling pathway)|interpro:IPR038319|interpro:IPR028848|interpro:IPR035745|interpro:IPR036028|reactome:R-RNO-186763|reactome:R-RNO-372708|reactome:R-RNO-4420097|reactome:R-RNO-8849471|mint:MINT-8030087(identity)|uniprotkb:Q63767(original identifier)	refseq:NP_001036236.1|refseq:NP_005347.3|ensembl:ENSG00000182866(gene)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|ensembl:ENST00000336890(transcript)|ensembl:ENST00000619559(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|dip:DIP-553N|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051249"(regulation of lymphocyte activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|mint:P06239|rcsb pdb:1BHF|rcsb pdb:1BHH|rcsb pdb:1CWD|rcsb pdb:1CWE|rcsb pdb:1FBZ|rcsb pdb:1H92|rcsb pdb:1IJR|rcsb pdb:1KIK|rcsb pdb:1LCJ|rcsb pdb:1LCK|rcsb pdb:1LKK|rcsb pdb:1LKL|rcsb pdb:1Q68|rcsb pdb:1Q69|rcsb pdb:1QPC|rcsb pdb:1QPD|rcsb pdb:1QPE|rcsb pdb:1QPJ|rcsb pdb:1X27|rcsb pdb:2IIM|rcsb pdb:2OF2|rcsb pdb:2OF4|rcsb pdb:2OFU|rcsb pdb:2OFV|rcsb pdb:2OG8|rcsb pdb:2PL0|rcsb pdb:2ZM1|rcsb pdb:2ZM4|rcsb pdb:2ZYB|rcsb pdb:3AC1|rcsb pdb:3AC2|rcsb pdb:3AC3|rcsb pdb:3AC4|rcsb pdb:3AC5|rcsb pdb:3AC8|rcsb pdb:3ACJ|rcsb pdb:3ACK|rcsb pdb:3AD4|rcsb pdb:3AD5|rcsb pdb:3AD6|rcsb pdb:3B2W|rcsb pdb:3BRH|rcsb pdb:3BYM|rcsb pdb:3BYO|rcsb pdb:3BYS|rcsb pdb:3BYU|rcsb pdb:3KMM|rcsb pdb:3KXZ|rcsb pdb:3LCK|rcsb pdb:3MPM|rcsb pdb:4C3F|rcsb pdb:4D8K|rcsb pdb:5MTM|rcsb pdb:5MTN|rcsb pdb:6H6A|rcsb pdb:6PDJ|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-167590|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-389948|reactome:R-HSA-6811558|reactome:R-HSA-9013407|reactome:R-HSA-9020558|reactome:R-HSA-9670439|reactome:R-HSA-9706374|mint:MINT-8030084(identity)|uniprotkb:P06239(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2005/10/31	2014/10/16	rogid:PwKKuaIaJmydKfuFPz05hT1UUow10116	rogid:AIdRYIcSNXmD2ovQiEn9N4CWr/M9606	intact-crc:31007C741828B4EF|rigid:rLbEebg/AeeytbtPNUWy/G1PFlU	false	binding-associated region:755-768(MINT-8030090)|phosphorylated residue:762-762(MINT-8030092)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)