#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02511 uniprotkb:Q9UJY1 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|ensembl:ENSP00000281938|uniprotkb:B2R6A6 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:hspb8_human(display_long)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:HSP22(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fontaine et al. (2005) pubmed:16225851 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-739088 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N ensembl:ENSG00000152137(gene)|ensembl:ENST00000281938(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0101031"(chaperone complex)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|reactome:R-HSA-3371571|refseq:NP_055180.1 - crc64:AE08BED46B7849CB - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/22 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606 intact-crc:284D2EEECBC40392|rigid:yrRRTjjn3Hws11r94aZFML1uZgc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJY1 uniprotkb:Q12988 intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|ensembl:ENSP00000281938|uniprotkb:B2R6A6 intact:EBI-713442|ensembl:ENSP00000303394 psi-mi:hspb8_human(display_long)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:HSP22(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym) psi-mi:hspb3_human(display_long)|uniprotkb:Heat shock 17 kDa protein(gene name synonym)|uniprotkb:HSPB3(gene name)|psi-mi:HSPB3(display_short)|uniprotkb:HSPL27(gene name synonym)|uniprotkb:HSP27(gene name synonym)|uniprotkb:Protein 3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fontaine et al. (2005) pubmed:16225851 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-739091 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000152137(gene)|ensembl:ENST00000281938(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0101031"(chaperone complex)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|reactome:R-HSA-3371571|refseq:NP_055180.1 ensembl:ENSG00000169271(gene)|ensembl:ENST00000302005(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016607"(nuclear speck)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR033894|rcsb pdb:6F2R|refseq:NP_006299.1 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/22 2014/10/16 rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606 rogid:g8JQ9Pld5s4HQdM+yJrMv7qgf+Y9606 intact-crc:69A023E245945AF7|rigid:Zp7CVMaOMdPZUvlgmN8J7ygRwrI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJY1 uniprotkb:O14558 intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|ensembl:ENSP00000281938|uniprotkb:B2R6A6 intact:EBI-739095|uniprotkb:O14551|uniprotkb:Q6NVI3|uniprotkb:Q96MG9|ensembl:ENSP00000004982 psi-mi:hspb8_human(display_long)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:HSP22(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym) psi-mi:hspb6_human(display_long)|uniprotkb:HSPB6(gene name)|psi-mi:HSPB6(display_short)|uniprotkb:Heat shock 20 kDa-like protein p20(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fontaine et al. (2005) pubmed:16225851 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-739106 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000152137(gene)|ensembl:ENST00000281938(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0101031"(chaperone complex)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|reactome:R-HSA-3371571|refseq:NP_055180.1 refseq:NP_653218.1|ensembl:ENSG00000004776(gene)|ensembl:ENST00000004982(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|rcsb pdb:4JUS|rcsb pdb:4JUT|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5LUM|rcsb pdb:5OK9|rcsb pdb:5OKF - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2005/11/22 2014/10/16 rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606 rogid:j4dxIh+W0/K9ofHyEuKfi2GZHBQ9606 intact-crc:F70ACE4FAF85A59B|rigid:sZ1C16yIVGzdvHggPlZ0Xbm5XZs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02511 uniprotkb:Q9UJY1 intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082 intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|ensembl:ENSP00000281938|uniprotkb:B2R6A6 psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym) psi-mi:hspb8_human(display_long)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:HSP22(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Fontaine et al. (2005) pubmed:16225851 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-739117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N ensembl:ENSG00000152137(gene)|ensembl:ENST00000281938(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0101031"(chaperone complex)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|reactome:R-HSA-3371571|refseq:NP_055180.1 - crc64:AE08BED46B7849CB - - taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/11/22 2014/10/16 rogid:495Z42oQhkAUdADrAEOKIC5oICo9606 rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606 intact-crc:6211603AFDB1C6C0|rigid:yrRRTjjn3Hws11r94aZFML1uZgc false green fluorescent protein tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O14558 uniprotkb:Q9UJY1 intact:EBI-739095|uniprotkb:O14551|uniprotkb:Q6NVI3|uniprotkb:Q96MG9|ensembl:ENSP00000004982 intact:EBI-739074|uniprotkb:Q6FIH3|uniprotkb:Q9UKS3|ensembl:ENSP00000281938|uniprotkb:B2R6A6 psi-mi:hspb6_human(display_long)|uniprotkb:HSPB6(gene name)|psi-mi:HSPB6(display_short)|uniprotkb:Heat shock 20 kDa-like protein p20(gene name synonym) psi-mi:hspb8_human(display_long)|uniprotkb:HSPB8(gene name)|psi-mi:HSPB8(display_short)|uniprotkb:CRYAC(gene name synonym)|uniprotkb:E2IG1(gene name synonym)|uniprotkb:HSP22(gene name synonym)|uniprotkb:PP1629(orf name)|uniprotkb:Alpha-crystallin C chain(gene name synonym)|uniprotkb:Small stress protein-like protein HSP22(gene name synonym)|uniprotkb:E2-induced gene 1 protein(gene name synonym)|uniprotkb:Protein kinase H11(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Fontaine et al. (2005) pubmed:16225851 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0469"(IntAct) intact:EBI-739164 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653218.1|ensembl:ENSG00000004776(gene)|ensembl:ENST00000004982(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|rcsb pdb:4JUS|rcsb pdb:4JUT|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5LUM|rcsb pdb:5OK9|rcsb pdb:5OKF ensembl:ENSG00000152137(gene)|ensembl:ENST00000281938(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0101031"(chaperone complex)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR042790|interpro:IPR043254|reactome:R-HSA-3371571|refseq:NP_055180.1 - - - - taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/11/22 2014/10/16 rogid:j4dxIh+W0/K9ofHyEuKfi2GZHBQ9606 rogid:SXMGg+TeGqU6CI+A4ypCqCGNYks9606 intact-crc:610E3739CD9A4D34|rigid:sZ1C16yIVGzdvHggPlZ0Xbm5XZs false green fluorescent protein tag:c-c green fluorescent protein tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)