#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O43586	uniprotkb:P35831	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	intact:EBI-2642957|uniprotkb:Q80UM4|ensembl:ENSMUSP00000030556	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:ptn12_mouse(display_long)|uniprotkb:Protein-tyrosine phosphatase P19(gene name synonym)|uniprotkb:Ptpn12(gene name)|psi-mi:Ptpn12(display_short)|uniprotkb:MPTP-PEST(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833624|mint:MINT-68633	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-1486672(identity)	refseq:NP_035333.2|ensembl:ENSMUSG00000028771(gene)|ensembl:ENSMUST00000030556(transcript)|go:"GO:0002102"(podosome)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042995"(cell projection)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012266(Protein-tyrosine phosphatase, non-receptor type-12)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P35831|reactome:R-MMU-1250196|reactome:R-MMU-182971|reactome:R-MMU-186797|reactome:R-MMU-8863795|mint:MINT-1486678(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4A|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/10/25	2014/10/16	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	rogid:GgHiRVbQuJTf7k7PeNejGiKHybQ10090	intact-crc:28C617A00B9478EA|rigid:KFK5Djde9dJKj0peyoZIMywKrbE	false	tag:?-?(MINT-1486673)	tag:?-?(MINT-1486679)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q53ZZ1	uniprotkb:O43586	intact:EBI-7833646|intact:MINT-1486456	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833641|mint:MINT-68634	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486483(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-1486474(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4A|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/10/25	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:2206ABBAE0EC06BC|rigid:eemmOc8heLzl9Bcyvg51wP1LTeA	false	-	tag:?-?(MINT-1486478)|binding-associated region:5-98(MINT-1486475)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P97814	uniprotkb:P41047	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	intact:EBI-7833717|ensembl:ENSMUSP00000000834|intact:MINT-1486494|uniprotkb:Q61217|uniprotkb:Q9R1F2	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:tnfl6_mouse(display_long)|uniprotkb:Faslg(gene name)|psi-mi:Faslg(display_short)|uniprotkb:Apt1lg1(gene name synonym)|uniprotkb:Fasl(gene name synonym)|uniprotkb:gld(gene name synonym)|uniprotkb:Tnfsf6(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:Cd95l(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833774|mint:MINT-68631	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486530(identity)	ensembl:ENSMUSG00000000817(gene)|ensembl:ENSMUST00000000834(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|refseq:NP_034307.1|mint:MINT-1486526(identity)	-	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	comment:mint|function:Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects|function:"A deficiency in this protein is the cause of generalized lymphoproliferation disease phenotype (gld). Gld mice present lymphadenopathy and autoantibody production. The phenotype is recessively inherited"|comment:"Stoichiometry: 1.0"	figure legend:F3A|comment:homomint|comment:mint	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2005/10/25	2014/10/16	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	rogid:khUzdex88jXBVTEvaBWA9etvAxc10090	intact-crc:2213AB50CCBDB5E3|rigid:fSFhJLmZmLGexZOSYniKRjNwnnQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41047	uniprotkb:P97814	intact:EBI-7833717|ensembl:ENSMUSP00000000834|intact:MINT-1486494|uniprotkb:Q61217|uniprotkb:Q9R1F2	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	psi-mi:tnfl6_mouse(display_long)|uniprotkb:Faslg(gene name)|psi-mi:Faslg(display_short)|uniprotkb:Apt1lg1(gene name synonym)|uniprotkb:Fasl(gene name synonym)|uniprotkb:gld(gene name synonym)|uniprotkb:Tnfsf6(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:Cd95l(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833827|mint:MINT-68624	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000817(gene)|ensembl:ENSMUST00000000834(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|refseq:NP_034307.1|mint:MINT-1486689(identity)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486696(identity)	-	comment:mint|function:Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects|function:"A deficiency in this protein is the cause of generalized lymphoproliferation disease phenotype (gld). Gld mice present lymphadenopathy and autoantibody production. The phenotype is recessively inherited"|comment:"Stoichiometry: 1.0"	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/10/25	2014/10/16	rogid:khUzdex88jXBVTEvaBWA9etvAxc10090	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	intact-crc:7C8D0D0B412604BA|rigid:fSFhJLmZmLGexZOSYniKRjNwnnQ	false	flag tag:?-?(MINT-1486690)	tag:?-?(MINT-1486697)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q53ZZ1	uniprotkb:P97814	intact:EBI-7833646|intact:MINT-1486456	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833845|mint:MINT-68626	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486589(identity)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486595(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/10/25	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	intact-crc:3CEEF90EE5A507D0|rigid:Cm2EpZ9Ey8jopkpZoFKEEN8kJ/E	false	tag:?-?(MINT-1486590)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q53ZZ1	uniprotkb:P97814	intact:EBI-7833646|intact:MINT-1486456	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833936|mint:MINT-68630	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486540(identity)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486544(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/10/25	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	intact-crc:8BFA88EFA942219B|rigid:Cm2EpZ9Ey8jopkpZoFKEEN8kJ/E	false	-	flag tag:?-?(MINT-1486545)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P97814	uniprotkb:Q53ZZ1	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	intact:EBI-7833646|intact:MINT-1486456	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7833891|mint:MINT-68629	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486664(identity)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486655(identity)	-	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2D|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/10/25	2014/10/16	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	intact-crc:15B03D7EE729E6F8|rigid:Cm2EpZ9Ey8jopkpZoFKEEN8kJ/E	false	-	binding-associated region:40-80(MINT-1486656)|flag tag:?-?(MINT-1486658)	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P97814	uniprotkb:Q53ZZ1	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	intact:EBI-7833646|intact:MINT-1486456	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834026|mint:MINT-68627	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486607(identity)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486603(identity)	-	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/10/25	2014/10/16	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	intact-crc:BC6FD178BAF09BA5|rigid:Cm2EpZ9Ey8jopkpZoFKEEN8kJ/E	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q53ZZ1	uniprotkb:O43586	intact:EBI-7833646|intact:MINT-1486456	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834037|mint:MINT-68628	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486557(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-1486561(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:homomint|comment:mint	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2005/10/25	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:967A8C26C78C1F94|rigid:eemmOc8heLzl9Bcyvg51wP1LTeA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P97814	uniprotkb:Q53ZZ1	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	intact:EBI-7833646|intact:MINT-1486456	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:"MI:0096"(pull down)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834056|mint:MINT-68622	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486728(identity)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486734(identity)	-	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F1A|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/25	2014/10/16	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	intact-crc:646653BB37374304|rigid:Cm2EpZ9Ey8jopkpZoFKEEN8kJ/E	false	tag:?-?(MINT-1486729)	binding-associated region:81-270(MINT-1486735)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P41047	uniprotkb:P97814	intact:EBI-7833717|ensembl:ENSMUSP00000000834|intact:MINT-1486494|uniprotkb:Q61217|uniprotkb:Q9R1F2	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	psi-mi:tnfl6_mouse(display_long)|uniprotkb:Faslg(gene name)|psi-mi:Faslg(display_short)|uniprotkb:Apt1lg1(gene name synonym)|uniprotkb:Fasl(gene name synonym)|uniprotkb:gld(gene name synonym)|uniprotkb:Tnfsf6(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:Cd95l(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:"MI:0096"(pull down)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834074|mint:MINT-68625	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000817(gene)|ensembl:ENSMUST00000000834(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|refseq:NP_034307.1|mint:MINT-1486571(identity)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486578(identity)	-	comment:mint|function:Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects|function:"A deficiency in this protein is the cause of generalized lymphoproliferation disease phenotype (gld). Gld mice present lymphadenopathy and autoantibody production. The phenotype is recessively inherited"|comment:"Stoichiometry: 1.0"	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	figure legend:F1B|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/25	2014/10/16	rogid:khUzdex88jXBVTEvaBWA9etvAxc10090	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	intact-crc:B53A3DBF06EB65F4|rigid:fSFhJLmZmLGexZOSYniKRjNwnnQ	false	glutathione s tranferase tag:?-?(MINT-1486572)	binding-associated region:361-415(MINT-1486579)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P97814	uniprotkb:P35831	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	intact:EBI-2642957|uniprotkb:Q80UM4|ensembl:ENSMUSP00000030556	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:ptn12_mouse(display_long)|uniprotkb:Protein-tyrosine phosphatase P19(gene name synonym)|uniprotkb:Ptpn12(gene name)|psi-mi:Ptpn12(display_short)|uniprotkb:MPTP-PEST(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834118|mint:MINT-68635	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486634(identity)	refseq:NP_035333.2|ensembl:ENSMUSG00000028771(gene)|ensembl:ENSMUST00000030556(transcript)|go:"GO:0002102"(podosome)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042995"(cell projection)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012266(Protein-tyrosine phosphatase, non-receptor type-12)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P35831|reactome:R-MMU-1250196|reactome:R-MMU-182971|reactome:R-MMU-186797|reactome:R-MMU-8863795|mint:MINT-1486630(identity)	-	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/10/25	2014/10/16	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	rogid:GgHiRVbQuJTf7k7PeNejGiKHybQ10090	intact-crc:F40FAC733B2C2725|rigid:BKpAS4EcEwTOfHRffBdcYNxkbB8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P41047	uniprotkb:P35831	intact:EBI-7833717|ensembl:ENSMUSP00000000834|intact:MINT-1486494|uniprotkb:Q61217|uniprotkb:Q9R1F2	intact:EBI-2642957|uniprotkb:Q80UM4|ensembl:ENSMUSP00000030556	psi-mi:tnfl6_mouse(display_long)|uniprotkb:Faslg(gene name)|psi-mi:Faslg(display_short)|uniprotkb:Apt1lg1(gene name synonym)|uniprotkb:Fasl(gene name synonym)|uniprotkb:gld(gene name synonym)|uniprotkb:Tnfsf6(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:Cd95l(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:ptn12_mouse(display_long)|uniprotkb:Protein-tyrosine phosphatase P19(gene name synonym)|uniprotkb:Ptpn12(gene name)|psi-mi:Ptpn12(display_short)|uniprotkb:MPTP-PEST(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834129|mint:MINT-68636	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000817(gene)|ensembl:ENSMUST00000000834(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|refseq:NP_034307.1|mint:MINT-1486646(identity)	refseq:NP_035333.2|ensembl:ENSMUSG00000028771(gene)|ensembl:ENSMUST00000030556(transcript)|go:"GO:0002102"(podosome)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042995"(cell projection)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012266(Protein-tyrosine phosphatase, non-receptor type-12)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P35831|reactome:R-MMU-1250196|reactome:R-MMU-182971|reactome:R-MMU-186797|reactome:R-MMU-8863795|mint:MINT-1486642(identity)	-	comment:mint|function:Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects|function:"A deficiency in this protein is the cause of generalized lymphoproliferation disease phenotype (gld). Gld mice present lymphadenopathy and autoantibody production. The phenotype is recessively inherited"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4B|comment:Interaction occurs only whether mPSTPIP is cotransfected|comment:homomint|comment:mint	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2005/10/25	2014/10/16	rogid:khUzdex88jXBVTEvaBWA9etvAxc10090	rogid:GgHiRVbQuJTf7k7PeNejGiKHybQ10090	intact-crc:2A09539F93B77B58|rigid:xTX0Ye+MPLcQdxEkQhtHiChWYLM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q53ZZ1	uniprotkb:O43586	intact:EBI-7833646|intact:MINT-1486456	intact:EBI-1050964|uniprotkb:O43585|uniprotkb:O95657|uniprotkb:B5BUK4|uniprotkb:B5BU74|ensembl:ENSP00000452746	psi-mi:q53zz1_human(display_long)|uniprotkb:TNFSF6(gene name)|psi-mi:TNFSF6(display_short)|uniprotkb:FASLG(gene name synonym)|uniprotkb:TNLG1A(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:FasL intracellular domain(gene name synonym)|uniprotkb:Receptor-binding FasL ectodomain(gene name synonym)|uniprotkb:SPPL2A-processed FasL form(gene name synonym)|uniprotkb:Soluble Fas ligand(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, membrane form(gene name synonym)|uniprotkb:Tumor necrosis factor ligand superfamily member 6, soluble form(gene name synonym)|uniprotkb:hCG_37643(orf name)	psi-mi:ppip1_human(display_long)|uniprotkb:CD2-binding protein 1(gene name synonym)|uniprotkb:H-PIP(gene name synonym)|uniprotkb:PSTPIP1(gene name)|psi-mi:PSTPIP1(display_short)|uniprotkb:CD2BP1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834207|mint:MINT-68632	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|refseq:NP_000630.1|interpro:IPR021184|reactome:R-HSA-5669034|interpro:IPR028326|mint:MINT-1486715(identity)	refseq:NP_003969.2|refseq:NP_001308064.1|refseq:NP_001308066.1|ensembl:ENSG00000140368(gene)|ensembl:ENST00000558012(transcript)|go:"GO:0001931"(uropod)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR030777|interpro:IPR031160|interpro:IPR036028|mint:O43586|rcsb pdb:2DIL|reactome:R-HSA-844456|reactome:R-HSA-9660826|mint:MINT-1486708(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F7|comment:homomint|comment:Same colocalization occurs in Hek-293T cells|comment:mint	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2005/10/25	2014/10/16	rogid:3/Op+1mSXMoGr/8mhnh1oCpQ4sQ9606	rogid:JWK4dCYdcVF6mKwe+hoOri1wwps9606	intact-crc:7C08A7728659B71C|rigid:eemmOc8heLzl9Bcyvg51wP1LTeA	false	green fluorescent protein tag:?-?(MINT-1486718)|binding-associated region:40-80(MINT-1486716)	myc tag:?-?(MINT-1486709)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:P41047	uniprotkb:P97814	intact:EBI-7833717|ensembl:ENSMUSP00000000834|intact:MINT-1486494|uniprotkb:Q61217|uniprotkb:Q9R1F2	intact:EBI-7484574|uniprotkb:Q4V9R4|intact:MINT-444743	psi-mi:tnfl6_mouse(display_long)|uniprotkb:Faslg(gene name)|psi-mi:Faslg(display_short)|uniprotkb:Apt1lg1(gene name synonym)|uniprotkb:Fasl(gene name synonym)|uniprotkb:gld(gene name synonym)|uniprotkb:Tnfsf6(gene name synonym)|uniprotkb:Fas antigen ligand(gene name synonym)|uniprotkb:Cd95l(gene name synonym)|uniprotkb:CD95 ligand(gene name synonym)	psi-mi:ppip1_mouse(display_long)|uniprotkb:Pstpip1(gene name)|psi-mi:Pstpip1(display_short)	psi-mi:"MI:0018"(two hybrid)	Baum et al. (2005)	pubmed:16204241|mint:MINT-5217980	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7834237|mint:MINT-68623	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000817(gene)|ensembl:ENSMUST00000000834(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005123"(death receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0048388"(endosomal lumen acidification)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060205"(cytoplasmic vesicle lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070848"(response to growth factor)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1903514"(release of sequestered calcium ion into cytosol by endoplasmic reticulum)|go:"GO:0009986"(cell surface)|go:"GO:1905782"(positive regulation of phosphatidylserine exposure on apoptotic cell surface)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR006053(Tumor necrosis factor alpha, beta and c)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR028326|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|refseq:NP_034307.1|mint:MINT-1486747(identity)	interpro:IPR027267|mint:P97814|interpro:IPR031160|interpro:IPR036028|refseq:NP_035323.2|interpro:IPR030777|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|go:"GO:0001725"(stress fiber)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|reactome:R-MMU-844456|mint:MINT-1486755(identity)	-	comment:mint|function:Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects|function:"A deficiency in this protein is the cause of generalized lymphoproliferation disease phenotype (gld). Gld mice present lymphadenopathy and autoantibody production. The phenotype is recessively inherited"|comment:"Stoichiometry: 1.0"	comment:mint|comment:homomint|function:"Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS, and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymeriszation required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through coupling PTPN12 to CD2"|comment:"Stoichiometry: 1.0"	figure legend:NFA|comment:homomint|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/10/25	2014/10/16	rogid:khUzdex88jXBVTEvaBWA9etvAxc10090	rogid:rC2GOU2BlaFNkA4+iB9pAYHJBDI10090	intact-crc:316C6260A007EE0D|rigid:fSFhJLmZmLGexZOSYniKRjNwnnQ	false	binding-associated region:1-80(MINT-1486748)|tag:?-?(MINT-1486750)	tag:?-?(MINT-1486759)|binding-associated region:130-415(MINT-1486756)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)