#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60784 uniprotkb:P0CG53 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Akutsu et al. (2005) pubmed:16199040|imex:IM-10789|mint:MINT-5217977 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7831838|mint:MINT-65929|imex:IM-10789-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N|mint:MINT-1486334(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-1486344(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|kd:409 micromolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/11 2014/10/16 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:158BE55C51450B8E|rigid:1bZ2Jt6IwIyCDkNlhdVH6kuHBGs false mutation decreasing interaction:289-289,285-285(MINT-1486338)|binding-associated region:215-309(MINT-1486335) binding-associated region:1-76(MINT-1486345) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CG53 uniprotkb:O60784 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:"MI:0096"(pull down) Akutsu et al. (2005) pubmed:16199040|imex:IM-10789|mint:MINT-5217977 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7831877|mint:MINT-65928|imex:IM-10789-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-1486370(identity) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N|mint:MINT-1486358(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/11 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 intact-crc:F0CDD27351EA385F|rigid:1bZ2Jt6IwIyCDkNlhdVH6kuHBGs false binding-associated region:1-76(MINT-1486371) mutation decreasing interaction:285-285,256-256(MINT-1486362)|binding-associated region:215-309(MINT-1486359)|tag:?-?(MINT-1486365) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60784 uniprotkb:P0CG53 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0096"(pull down) Akutsu et al. (2005) pubmed:16199040|imex:IM-10789|mint:MINT-5217977 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7831908|mint:MINT-65930|imex:IM-10789-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N|mint:MINT-1486381(identity) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-1486390(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/11 2014/10/16 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 intact-crc:C7DC005F26574371|rigid:1bZ2Jt6IwIyCDkNlhdVH6kuHBGs false binding-associated region:215-309(MINT-1486382)|tag:?-?(MINT-1486385) tag:?-?(MINT-1486396)|mutation decreasing interaction:44-44(MINT-1486394)|binding-associated region:1-76(MINT-1486391) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CG53 uniprotkb:O60784 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Akutsu et al. (2005) pubmed:16199040|imex:IM-10789|mint:MINT-5217977 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7831950|mint:MINT-65931|imex:IM-10789-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-1486420(identity) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N|mint:MINT-1486407(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/11 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 intact-crc:BCF669226A8D53A8|rigid:1bZ2Jt6IwIyCDkNlhdVH6kuHBGs false binding-associated region:1-76(MINT-1486421) binding-associated region:215-309(MINT-1486408)|tag:?-?(MINT-1486414)|mutation decreasing interaction:285-285,256-256(MINT-1486411) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0CG53 uniprotkb:O60784 intact:EBI-5333021|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62990|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:Q3T0V5|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|ensembl:ENSBTAP00000022919 intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74 psi-mi:ubb_bovin(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short) psi-mi:"MI:0013"(biophysical) Akutsu et al. (2005) pubmed:16199040|imex:IM-10789|mint:MINT-5217977 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7831991|mint:MINT-65927|imex:IM-10789-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_776558.1|ensembl:ENSBTAG00000017246(gene)|ensembl:ENSBTAT00000022919(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG53|rcsb pdb:5TR4|reactome:R-BTA-110312|reactome:R-BTA-110320|reactome:R-BTA-1234176|reactome:R-BTA-1253288|reactome:R-BTA-1295596|reactome:R-BTA-1358803|reactome:R-BTA-182971|reactome:R-BTA-187577|reactome:R-BTA-195253|reactome:R-BTA-201681|reactome:R-BTA-205043|reactome:R-BTA-209560|reactome:R-BTA-2173795|reactome:R-BTA-2565942|reactome:R-BTA-3134975|reactome:R-BTA-3769402|reactome:R-BTA-450302|reactome:R-BTA-4608870|reactome:R-BTA-4641257|reactome:R-BTA-4641263|reactome:R-BTA-5357905|reactome:R-BTA-5357956|reactome:R-BTA-5610780|reactome:R-BTA-5632684|reactome:R-BTA-5654726|reactome:R-BTA-5654727|reactome:R-BTA-5654732|reactome:R-BTA-5654733|reactome:R-BTA-5656169|reactome:R-BTA-5668541|reactome:R-BTA-5675221|reactome:R-BTA-5675482|reactome:R-BTA-5689877|reactome:R-BTA-5689880|reactome:R-BTA-5689896|reactome:R-BTA-5689901|reactome:R-BTA-5696394|reactome:R-BTA-5696395|reactome:R-BTA-6783310|reactome:R-BTA-6804757|reactome:R-BTA-68827|reactome:R-BTA-69231|reactome:R-BTA-8849469|reactome:R-BTA-8854050|reactome:R-BTA-8866652|reactome:R-BTA-8866654|reactome:R-BTA-8939902|reactome:R-BTA-8941858|reactome:R-BTA-8951664|reactome:R-BTA-901032|reactome:R-BTA-912631|reactome:R-BTA-917937|reactome:R-BTA-9705462|reactome:R-BTA-9706369|reactome:R-BTA-9708530|reactome:R-BTA-983168|mint:MINT-1486442(identity) ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N|mint:MINT-1486434(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/11 2014/10/16 rogid:oFGJ21b+3otfDmmlsVIrTz2U6fg9913 rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606 intact-crc:87C03ADF4EDB8729|rigid:1bZ2Jt6IwIyCDkNlhdVH6kuHBGs false binding-associated region:1-76(MINT-1486443) binding-associated region:215-309(MINT-1486435) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)