#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P02510	uniprotkb:P10279	intact:EBI-7824601|ensembl:ENSBTAP00000068917|intact:MINT-1486058|uniprotkb:O46508|uniprotkb:Q3SZQ9	intact:EBI-7430632|uniprotkb:Q6UL06|uniprotkb:Q7YRN3|uniprotkb:Q01880|uniprotkb:Q5UK69|uniprotkb:Q6UL03|uniprotkb:Q0VD57|intact:MINT-1486044|uniprotkb:A1YVV9|uniprotkb:Q5UJJ5|uniprotkb:Q8MJI7|uniprotkb:Q6UL05|uniprotkb:Q6UL04|uniprotkb:Q5UK71|uniprotkb:Q5UJM6	psi-mi:cryab_bovin(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)	psi-mi:prio_bovin(display_long)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRP(gene name synonym)|uniprotkb:Major scrapie-associated fibril protein 1(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Sun et al. (2005)	pubmed:16198347|mint:MINT-5217971	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824640|mint:MINT-65940	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000000434(gene)|ensembl:ENSBTAT00000087415(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|refseq:NP_776715.1|dip:DIP-43761N|mint:MINT-1486074(identity)	rcsb pdb:4YX2|rcsb pdb:2RU7|refseq:NP_001258555.1|rcsb pdb:1DWY|rcsb pdb:1SKH|interpro:IPR022416|rcsb pdb:2HH0|rcsb pdb:2RSK|rcsb pdb:1DWZ|interpro:IPR025860|refseq:NP_851358.2|rcsb pdb:1DX1|rcsb pdb:1DX0|interpro:IPR000817(Prion protein)|go:"GO:0005507"(copper ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR036924|mint:MINT-1486070(identity)	-	function:May contribute to the transparency and refractive index of the lens|comment:mint|comment:"Stoichiometry: 1.0"	function:The function of PrP is not known. PrP is encoded in the host genome and is expressed both in normal and infected cells|function:"Found in high quantity in the brain of humans and animals infected with degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), etc"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	figure legend:F4|kd:0.398 micromolar|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/11	2014/10/16	rogid:JO9UwRfAEJ/sIT6nDDS2Hs5XxAI9913	rogid:aQnrXt9KiwWlGbP8RhP3X6bWHzw9913	intact-crc:A7A5F07A1DA47C27|rigid:NeS32GmqB+ojj7T7Y42ljcqST9g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P02510	uniprotkb:P10279	intact:EBI-7824601|ensembl:ENSBTAP00000068917|intact:MINT-1486058|uniprotkb:O46508|uniprotkb:Q3SZQ9	intact:EBI-7430632|uniprotkb:Q6UL06|uniprotkb:Q7YRN3|uniprotkb:Q01880|uniprotkb:Q5UK69|uniprotkb:Q6UL03|uniprotkb:Q0VD57|intact:MINT-1486044|uniprotkb:A1YVV9|uniprotkb:Q5UJJ5|uniprotkb:Q8MJI7|uniprotkb:Q6UL05|uniprotkb:Q6UL04|uniprotkb:Q5UK71|uniprotkb:Q5UJM6	psi-mi:cryab_bovin(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)	psi-mi:prio_bovin(display_long)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRP(gene name synonym)|uniprotkb:Major scrapie-associated fibril protein 1(gene name synonym)	psi-mi:"MI:0045"(experimental interaction detection)	Sun et al. (2005)	pubmed:16198347|mint:MINT-5217971	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824653|mint:MINT-65942	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000000434(gene)|ensembl:ENSBTAT00000087415(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|refseq:NP_776715.1|dip:DIP-43761N|mint:MINT-1486129(identity)	rcsb pdb:4YX2|rcsb pdb:2RU7|refseq:NP_001258555.1|rcsb pdb:1DWY|rcsb pdb:1SKH|interpro:IPR022416|rcsb pdb:2HH0|rcsb pdb:2RSK|rcsb pdb:1DWZ|interpro:IPR025860|refseq:NP_851358.2|rcsb pdb:1DX1|rcsb pdb:1DX0|interpro:IPR000817(Prion protein)|go:"GO:0005507"(copper ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR036924|mint:MINT-1486122(identity)	-	function:May contribute to the transparency and refractive index of the lens|comment:mint|comment:"Stoichiometry: 1.0"	function:The function of PrP is not known. PrP is encoded in the host genome and is expressed both in normal and infected cells|function:"Found in high quantity in the brain of humans and animals infected with degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), etc"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/10/11	2014/10/16	rogid:JO9UwRfAEJ/sIT6nDDS2Hs5XxAI9913	rogid:aQnrXt9KiwWlGbP8RhP3X6bWHzw9913	intact-crc:3AF54BD480B10143|rigid:NeS32GmqB+ojj7T7Y42ljcqST9g	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P10279	uniprotkb:P02510	intact:EBI-7430632|uniprotkb:Q6UL06|uniprotkb:Q7YRN3|uniprotkb:Q01880|uniprotkb:Q5UK69|uniprotkb:Q6UL03|uniprotkb:Q0VD57|intact:MINT-1486044|uniprotkb:A1YVV9|uniprotkb:Q5UJJ5|uniprotkb:Q8MJI7|uniprotkb:Q6UL05|uniprotkb:Q6UL04|uniprotkb:Q5UK71|uniprotkb:Q5UJM6	intact:EBI-7824601|ensembl:ENSBTAP00000068917|intact:MINT-1486058|uniprotkb:O46508|uniprotkb:Q3SZQ9	psi-mi:prio_bovin(display_long)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRP(gene name synonym)|uniprotkb:Major scrapie-associated fibril protein 1(gene name synonym)	psi-mi:cryab_bovin(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)	psi-mi:"MI:0398"(two hybrid pooling approach)	Sun et al. (2005)	pubmed:16198347|mint:MINT-5217971	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824674|mint:MINT-65939	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4YX2|rcsb pdb:2RU7|refseq:NP_001258555.1|rcsb pdb:1DWY|rcsb pdb:1SKH|interpro:IPR022416|rcsb pdb:2HH0|rcsb pdb:2RSK|rcsb pdb:1DWZ|interpro:IPR025860|refseq:NP_851358.2|rcsb pdb:1DX1|rcsb pdb:1DX0|interpro:IPR000817(Prion protein)|go:"GO:0005507"(copper ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR036924|mint:MINT-1486085(identity)	ensembl:ENSBTAG00000000434(gene)|ensembl:ENSBTAT00000087415(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|refseq:NP_776715.1|dip:DIP-43761N|mint:MINT-1486093(identity)	-	function:The function of PrP is not known. PrP is encoded in the host genome and is expressed both in normal and infected cells|function:"Found in high quantity in the brain of humans and animals infected with degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), etc"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	function:May contribute to the transparency and refractive index of the lens|comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F1|comment:homomint|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2005/10/11	2014/10/16	rogid:aQnrXt9KiwWlGbP8RhP3X6bWHzw9913	rogid:JO9UwRfAEJ/sIT6nDDS2Hs5XxAI9913	intact-crc:50B49E71FA80F07F|rigid:NeS32GmqB+ojj7T7Y42ljcqST9g	false	tag:?-?(MINT-1486088)|binding-associated region:25-242(MINT-1486086)	tag:?-?(MINT-1486094)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10279	uniprotkb:P02510	intact:EBI-7430632|uniprotkb:Q6UL06|uniprotkb:Q7YRN3|uniprotkb:Q01880|uniprotkb:Q5UK69|uniprotkb:Q6UL03|uniprotkb:Q0VD57|intact:MINT-1486044|uniprotkb:A1YVV9|uniprotkb:Q5UJJ5|uniprotkb:Q8MJI7|uniprotkb:Q6UL05|uniprotkb:Q6UL04|uniprotkb:Q5UK71|uniprotkb:Q5UJM6	intact:EBI-7824601|ensembl:ENSBTAP00000068917|intact:MINT-1486058|uniprotkb:O46508|uniprotkb:Q3SZQ9	psi-mi:prio_bovin(display_long)|uniprotkb:PRNP(gene name)|psi-mi:PRNP(display_short)|uniprotkb:PRP(gene name synonym)|uniprotkb:Major scrapie-associated fibril protein 1(gene name synonym)	psi-mi:cryab_bovin(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)	psi-mi:"MI:0428"(imaging technique)	Sun et al. (2005)	pubmed:16198347|mint:MINT-5217971	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7824722|mint:MINT-65941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4YX2|rcsb pdb:2RU7|refseq:NP_001258555.1|rcsb pdb:1DWY|rcsb pdb:1SKH|interpro:IPR022416|rcsb pdb:2HH0|rcsb pdb:2RSK|rcsb pdb:1DWZ|interpro:IPR025860|refseq:NP_851358.2|rcsb pdb:1DX1|rcsb pdb:1DX0|interpro:IPR000817(Prion protein)|go:"GO:0005507"(copper ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR036924|mint:MINT-1486105(identity)	ensembl:ENSBTAG00000000434(gene)|ensembl:ENSBTAT00000087415(transcript)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|refseq:NP_776715.1|dip:DIP-43761N|mint:MINT-1486112(identity)	-	function:The function of PrP is not known. PrP is encoded in the host genome and is expressed both in normal and infected cells|function:"Found in high quantity in the brain of humans and animals infected with degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), etc"|comment:mint|comment:homomint|comment:"Stoichiometry: 1.0"	function:May contribute to the transparency and refractive index of the lens|comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:-4(in vivo)|taxid:-4(in vivo)	-	2005/10/11	2014/10/16	rogid:aQnrXt9KiwWlGbP8RhP3X6bWHzw9913	rogid:JO9UwRfAEJ/sIT6nDDS2Hs5XxAI9913	intact-crc:66DEADAD4710B6A3|rigid:NeS32GmqB+ojj7T7Y42ljcqST9g	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)