#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P01110 uniprotkb:P52162 intact:EBI-7820803|intact:MINT-1367446 intact:EBI-7820818|ensembl:ENSGALP00000044694|intact:MINT-1367457 psi-mi:myc_avimc(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:max_chick(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:11868(avimc)|taxid:11868(Avian myelocytomatosis virus MC29) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7820834|mint:MINT-68516 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036638|refseq:NP_045935.1|mint:MINT-1367473(identity) refseq:XP_015141578.1|ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000065978(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:MINT-1367480(identity) - comment:mint|function:Transforms avian and murine macrophages and fibroblasts as well as murine B-lymphoid cells|comment:"Stoichiometry: 1.0" comment:mint|function:Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor|comment:"Stoichiometry: 1.0" figure legend:F4|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/21 2014/10/16 rogid:PTymb8K6Uy8O5/KDBi6joL6Znkg11868 rogid:ZtKEIsnIG+IpaIW8/b0skvMWjjI9031 intact-crc:7259631AE0C4EB5B|rigid:LtgD5FiH3/syZpsWY4g1Ga4J7tY false binding-associated region:?-?(MINT-1367474) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52162-2 uniprotkb:P01109 intact:EBI-7820874|ensembl:ENSGALP00000057649|intact:MINT-1367468 intact:EBI-7820897|ensembl:ENSGALP00000054503|intact:MINT-1367509 psi-mi:p52162-2(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:myc_chick(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7820940|mint:MINT-68518 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000052061(transcript)|intact:EBI-7820818(max_chick)|mint:MINT-1367584(identity) refseq:XP_015138575.1|ensembl:ENSGALG00000033631(gene)|ensembl:ENSGALT00000080250(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048730"(epidermis morphogenesis)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-GGA-5689880|reactome:R-GGA-9018519|refseq:NP_001026123.1|mint:MINT-1367575(identity) - comment:mint|isoform-comment:No experimental confirmation available.|comment:"Stoichiometry: 1.0" comment:mint|function:Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes|function:Overexpression of C-Myc is implicated in the etiology of a variety of hematopoietic tumors|comment:"Stoichiometry: 1.0" figure legend:F4 F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/21 2014/10/16 rogid:qSiwcxs5z4Ix9q9/xJ/aYF8jVgg9031 rogid:ygUGbPfPpLhRdHv1AQepb3ntPOU9031 intact-crc:1837E331A4CC80FE|rigid:tn0UJm3igtOPZKYqFTJ3wqzZ0i0 false - binding-associated region:387-399(MINT-1367576)|mutation decreasing interaction:383-383(MINT-1367579) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P52162-2 uniprotkb:P01110 intact:EBI-7820874|ensembl:ENSGALP00000057649|intact:MINT-1367468 intact:EBI-7820803|intact:MINT-1367446 psi-mi:p52162-2(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:myc_avimc(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:11868(avimc)|taxid:11868(Avian myelocytomatosis virus MC29) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7820869|mint:MINT-68517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000052061(transcript)|intact:EBI-7820818(max_chick)|mint:MINT-1367567(identity) interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036638|refseq:NP_045935.1|mint:MINT-1367560(identity) - comment:mint|isoform-comment:No experimental confirmation available.|comment:"Stoichiometry: 1.0" comment:mint|function:Transforms avian and murine macrophages and fibroblasts as well as murine B-lymphoid cells|comment:"Stoichiometry: 1.0" figure legend:F4|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/21 2014/10/16 rogid:qSiwcxs5z4Ix9q9/xJ/aYF8jVgg9031 rogid:PTymb8K6Uy8O5/KDBi6joL6Znkg11868 intact-crc:2F5014FCDAF5E036|rigid:H3nQL8FRNWnfu0Pud4Z0hSFZdBg false - binding-associated region:?-?(MINT-1367561) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01109 uniprotkb:P52162 intact:EBI-7820897|ensembl:ENSGALP00000054503|intact:MINT-1367509 intact:EBI-7820818|ensembl:ENSGALP00000044694|intact:MINT-1367457 psi-mi:myc_chick(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:max_chick(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7820960|mint:MINT-68519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_015138575.1|ensembl:ENSGALG00000033631(gene)|ensembl:ENSGALT00000080250(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048730"(epidermis morphogenesis)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-GGA-5689880|reactome:R-GGA-9018519|refseq:NP_001026123.1|mint:MINT-1367592(identity) refseq:XP_015141578.1|ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000065978(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:MINT-1367601(identity) - comment:mint|function:Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes|function:Overexpression of C-Myc is implicated in the etiology of a variety of hematopoietic tumors|comment:"Stoichiometry: 1.0" comment:mint|function:Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor|comment:"Stoichiometry: 1.0" figure legend:F4 F6B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/10/21 2014/10/16 rogid:ygUGbPfPpLhRdHv1AQepb3ntPOU9031 rogid:ZtKEIsnIG+IpaIW8/b0skvMWjjI9031 intact-crc:BB1B946353EBF353|rigid:69pLhHQOyrzaHfqRa+cVDQsQcio false mutation decreasing interaction:383-383(MINT-1367596)|binding-associated region:387-399(MINT-1367593) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01109 uniprotkb:P52162 intact:EBI-7820897|ensembl:ENSGALP00000054503|intact:MINT-1367509 intact:EBI-7820818|ensembl:ENSGALP00000044694|intact:MINT-1367457 psi-mi:myc_chick(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:max_chick(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7821044|mint:MINT-68521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_015138575.1|ensembl:ENSGALG00000033631(gene)|ensembl:ENSGALT00000080250(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048730"(epidermis morphogenesis)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-GGA-5689880|reactome:R-GGA-9018519|refseq:NP_001026123.1|mint:MINT-1367528(identity) refseq:XP_015141578.1|ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000065978(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:MINT-1367522(identity) - comment:mint|function:Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes|function:Overexpression of C-Myc is implicated in the etiology of a variety of hematopoietic tumors|comment:"Stoichiometry: 1.0" comment:mint|function:Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor|comment:"Stoichiometry: 1.0" figure legend:F5|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/10/21 2014/10/16 rogid:ygUGbPfPpLhRdHv1AQepb3ntPOU9031 rogid:ZtKEIsnIG+IpaIW8/b0skvMWjjI9031 intact-crc:D4E8E465F98631CC|rigid:69pLhHQOyrzaHfqRa+cVDQsQcio false tag:?-?(MINT-1367532)|binding-associated region:387-399(MINT-1367529) tag:?-?(MINT-1367523) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01110 uniprotkb:P52162 intact:EBI-7820803|intact:MINT-1367446 intact:EBI-7820818|ensembl:ENSGALP00000044694|intact:MINT-1367457 psi-mi:myc_avimc(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:max_chick(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:11868(avimc)|taxid:11868(Avian myelocytomatosis virus MC29) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7820989|mint:MINT-68520 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036638|refseq:NP_045935.1|mint:MINT-1367496(identity) refseq:XP_015141578.1|ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000065978(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:MINT-1367490(identity) - comment:mint|function:Transforms avian and murine macrophages and fibroblasts as well as murine B-lymphoid cells|comment:"Stoichiometry: 1.0" comment:mint|function:Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor|comment:"Stoichiometry: 1.0" figure legend:F5|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/10/21 2014/10/16 rogid:PTymb8K6Uy8O5/KDBi6joL6Znkg11868 rogid:ZtKEIsnIG+IpaIW8/b0skvMWjjI9031 intact-crc:CEDD3ACEC423D021|rigid:LtgD5FiH3/syZpsWY4g1Ga4J7tY false tag:?-?(MINT-1367500)|binding-associated region:?-?(MINT-1367497) tag:?-?(MINT-1367491) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01110 uniprotkb:P52162-2 intact:EBI-7820803|intact:MINT-1367446 intact:EBI-7820874|ensembl:ENSGALP00000057649|intact:MINT-1367468 psi-mi:myc_avimc(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:p52162-2(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:11868(avimc)|taxid:11868(Avian myelocytomatosis virus MC29) taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7821121|mint:MINT-68523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR036638|refseq:NP_045935.1|mint:MINT-1367547(identity) ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000052061(transcript)|intact:EBI-7820818(max_chick)|mint:MINT-1367541(identity) - comment:mint|function:Transforms avian and murine macrophages and fibroblasts as well as murine B-lymphoid cells|comment:"Stoichiometry: 1.0" comment:mint|isoform-comment:No experimental confirmation available.|comment:"Stoichiometry: 1.0" figure legend:F5|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/10/21 2014/10/16 rogid:PTymb8K6Uy8O5/KDBi6joL6Znkg11868 rogid:qSiwcxs5z4Ix9q9/xJ/aYF8jVgg9031 intact-crc:B7BB538DCB827D0B|rigid:H3nQL8FRNWnfu0Pud4Z0hSFZdBg false binding-associated region:?-?(MINT-1367548)|tag:?-?(MINT-1367551) tag:?-?(MINT-1367542) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P01109 uniprotkb:P52162-2 intact:EBI-7820897|ensembl:ENSGALP00000054503|intact:MINT-1367509 intact:EBI-7820874|ensembl:ENSGALP00000057649|intact:MINT-1367468 psi-mi:myc_chick(display_long)|uniprotkb:MYC(gene name)|psi-mi:MYC(display_short) psi-mi:p52162-2(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Crouch et al. (2005) pubmed:16166655|mint:MINT-5217951 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7821095|mint:MINT-68522 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_015138575.1|ensembl:ENSGALG00000033631(gene)|ensembl:ENSGALT00000080250(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048730"(epidermis morphogenesis)|interpro:IPR002418(Transcription regulator Myc)|interpro:IPR003327(Leucine zipper, Myc)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR012682(Transcription regulator Myc, N-terminal)|interpro:IPR036638|reactome:R-GGA-5689880|reactome:R-GGA-9018519|refseq:NP_001026123.1|mint:MINT-1367615(identity) ensembl:ENSGALG00000032249(gene)|ensembl:ENSGALT00000052061(transcript)|intact:EBI-7820818(max_chick)|mint:MINT-1367609(identity) - comment:mint|function:Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes|function:Overexpression of C-Myc is implicated in the etiology of a variety of hematopoietic tumors|comment:"Stoichiometry: 1.0" comment:mint|isoform-comment:No experimental confirmation available.|comment:"Stoichiometry: 1.0" figure legend:F5 F6|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/10/21 2014/10/16 rogid:ygUGbPfPpLhRdHv1AQepb3ntPOU9031 rogid:qSiwcxs5z4Ix9q9/xJ/aYF8jVgg9031 intact-crc:DB34084A3F710B15|rigid:tn0UJm3igtOPZKYqFTJ3wqzZ0i0 false tag:?-?(MINT-1367621)|binding-associated region:387-399(MINT-1367616)|mutation decreasing interaction:383-383(MINT-1367619) tag:?-?(MINT-1367610) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)