#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O12161 uniprotkb:O15350-2 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389623|intact:EBI-7805787|intact:MINT-97789|intact:EBI-7164687|intact:EBI-7164925|intact:EBI-7165337|intact:EBI-7164778|intact:EBI-7165149|intact:EBI-7805610|intact:EBI-7805860|intact:EBI-7807200|intact:EBI-7806075|ensembl:ENSP00000346423 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-2(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7805604|mint:MINT-72993 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366751(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000354437(transcript)|mint:MINT-1366761(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:Produced by alternative splicing of isoform Alpha.|comment:"Stoichiometry: 1.0" figure legend:F1D F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:Tb9otYnljMLCjg7j3Wock+pyNnE9606 intact-crc:DB6746F86C18F9EE|rigid:Sv47iRXWVEP/mJhcKbhoBvnqTKQ false glutathione s tranferase tag:?-?(MINT-1366755)|binding-associated region:30-40(MINT-1366752) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O15350-1 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0096"(pull down) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7805680|mint:MINT-72994 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366551(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|mint:MINT-1366561(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D F2C F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 intact-crc:1568BD36447F0D72|rigid:9kADzsbqCQxh5TfDbmk1MrQgCFY false binding-associated region:30-40(MINT-1366552)|glutathione s tranferase tag:?-?(MINT-1366555) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O60563 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0096"(pull down) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7805700|mint:MINT-73002 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366665(identity) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N|mint:MINT-1366676(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F8|comment:Interaction is inhibited in presence of p73 alpha or p73 beta|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 intact-crc:6ED33BCBD9AE37D3|rigid:HsW8hl6k/6Pdc9aSx2v3VntglgY false glutathione s tranferase tag:?-?(MINT-1366670)|binding-associated region:?-?(MINT-1366666)|mutation decreasing interaction:2-36(MINT-1366668) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O15350-1 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805748|mint:MINT-72991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366769(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|mint:MINT-1366778(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 intact-crc:9E3D16A4C14F548C|rigid:9kADzsbqCQxh5TfDbmk1MrQgCFY false binding-associated region:?-?(MINT-1366770)|tag:?-?(MINT-1366772) ha tag:?-?(MINT-1366779) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O15350-1 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805833|mint:MINT-72996 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366640(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|mint:MINT-1366635(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 intact-crc:B756AF8E827D6A31|rigid:9kADzsbqCQxh5TfDbmk1MrQgCFY false binding-associated region:?-?(MINT-1366641) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O12161 uniprotkb:O15350-2 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389623|intact:EBI-7805787|intact:MINT-97789|intact:EBI-7164687|intact:EBI-7164925|intact:EBI-7165337|intact:EBI-7164778|intact:EBI-7165149|intact:EBI-7805610|intact:EBI-7805860|intact:EBI-7807200|intact:EBI-7806075|ensembl:ENSP00000346423 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-2(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805781|mint:MINT-72992 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366805(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000354437(transcript)|mint:MINT-1366815(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:Produced by alternative splicing of isoform Alpha.|comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:Tb9otYnljMLCjg7j3Wock+pyNnE9606 intact-crc:8109BBB575408CF0|rigid:Sv47iRXWVEP/mJhcKbhoBvnqTKQ false binding-associated region:30-40(MINT-1366806)|glutathione s tranferase tag:?-?(MINT-1366809) ha tag:?-?(MINT-1366816) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O15350-2 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389623|intact:EBI-7805787|intact:MINT-97789|intact:EBI-7164687|intact:EBI-7164925|intact:EBI-7165337|intact:EBI-7164778|intact:EBI-7165149|intact:EBI-7805610|intact:EBI-7805860|intact:EBI-7807200|intact:EBI-7806075|ensembl:ENSP00000346423 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-2(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805872|mint:MINT-72997 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366625(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000354437(transcript)|mint:MINT-1366620(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:Produced by alternative splicing of isoform Alpha.|comment:"Stoichiometry: 1.0" figure legend:F7A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:Tb9otYnljMLCjg7j3Wock+pyNnE9606 intact-crc:90ECA377228C83EA|rigid:Sv47iRXWVEP/mJhcKbhoBvnqTKQ false binding-associated region:?-?(MINT-1366626) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O12161 uniprotkb:O60563 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805904|mint:MINT-72999 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366650(identity) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N|mint:MINT-1366657(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 intact-crc:EC194CA5568C6CA1|rigid:HsW8hl6k/6Pdc9aSx2v3VntglgY false binding-associated region:?-?(MINT-1366651) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O12161 uniprotkb:Q09472 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805888|mint:MINT-72998 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366591(identity) refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|mint:MINT-1366586(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 intact-crc:0DF94E2213CB67D7|rigid:Y3RnagzUVilH3U0puAreNrfiwMw false binding-associated region:?-?(MINT-1366592) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O15350-1 uniprotkb:O60563 intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805975|mint:MINT-73001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|mint:MINT-1366578(identity) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N|mint:MINT-1366573(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 intact-crc:3B593F0E05791EC3|rigid:HcRKfOaopKeSrVj61S1Quc84j5A false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O12161 uniprotkb:O15350-1 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7805931|mint:MINT-73000 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366685(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|mint:MINT-1366692(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 intact-crc:C3AD635757B58905|rigid:9kADzsbqCQxh5TfDbmk1MrQgCFY false binding-associated region:?-?(MINT-1366686) - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O12161 uniprotkb:O15350-1 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389619|intact:EBI-7470973|intact:EBI-7471076|intact:EBI-7471099|intact:EBI-7471381|intact:EBI-7807052|intact:EBI-7807687|intact:EBI-7164857|intact:EBI-7805920|intact:EBI-7164970|intact:EBI-7471237|intact:EBI-7807120|intact:EBI-7807786|intact:EBI-7805669|intact:EBI-8585153|intact:EBI-7807280|intact:EBI-7807483|intact:EBI-7805754|intact:EBI-7806017|intact:EBI-7470879|intact:EBI-7471009|intact:EBI-7806994|intact:MINT-97785|intact:EBI-7805839|intact:EBI-7088676|intact:EBI-7807086|intact:EBI-7807154|intact:EBI-7805964|ensembl:ENSP00000367545 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-1(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7806011|mint:MINT-72989 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366741(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|mint:MINT-1366734(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 intact-crc:7E510C3D00B3474E|rigid:9kADzsbqCQxh5TfDbmk1MrQgCFY false binding-associated region:?-?(MINT-1366742) ha tag:?-?(MINT-1366735) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:Q92831 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7806107|mint:MINT-72995 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366610(identity) ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N|mint:MINT-1366603(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F7A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606 intact-crc:246CC9F4A55DE41A|rigid:DjCGU/vhOzVbVEy0KPGp/WLjkPE false binding-associated region:?-?(MINT-1366611) flag tag:?-?(MINT-1366604) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O15350-2 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389623|intact:EBI-7805787|intact:MINT-97789|intact:EBI-7164687|intact:EBI-7164925|intact:EBI-7165337|intact:EBI-7164778|intact:EBI-7165149|intact:EBI-7805610|intact:EBI-7805860|intact:EBI-7807200|intact:EBI-7806075|ensembl:ENSP00000346423 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:o15350-2(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7806069|mint:MINT-72990 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366724(identity) intact:EBI-389606(p73_human)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000354437(transcript)|mint:MINT-1366717(identity) - comment:mint|comment:"Stoichiometry: 1.0" isoform-comment:Produced by alternative splicing of isoform Alpha.|comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:Tb9otYnljMLCjg7j3Wock+pyNnE9606 intact-crc:13AF4406AB6247B4|rigid:Sv47iRXWVEP/mJhcKbhoBvnqTKQ false binding-associated region:?-?(MINT-1366725) ha tag:?-?(MINT-1366718) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O12161 uniprotkb:O15350 intact:EBI-7805622|psi-mi:MINT-5231871|intact:MINT-1366539 intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545 psi-mi:tat_hv192(display_long)|uniprotkb:Transactivating regulatory protein(gene name synonym)|uniprotkb:tat(gene name)|psi-mi:tat(display_short) psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Amini et al. (2005) pubmed:16135803|mint:MINT-5217930|doi:10.1128/MCB.25.18.8126-8138.2005 taxid:388812(hv192)|taxid:388812("Human immunodeficiency virus type 1 group M subtype C (isolate 92BR025)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7806223|mint:MINT-73004 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001070"(RNA-binding transcription regulator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0042805"(actinin binding)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046872"(metal ion binding)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:1990970"(trans-activation response element binding)|interpro:IPR036963|interpro:IPR001831("Immunodeficiency virus transactivating regulatory protein (Tat)")|mint:MINT-1366702(identity) ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N|mint:MINT-1366709(identity) go:"GO:0005634"(nucleus) comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F9|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2005/12/02 2014/10/16 rogid:fEtZxNoQ0HTYQtJ91C0huywJKBA388812 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 intact-crc:F4C095EF56D75645|rigid:9kADzsbqCQxh5TfDbmk1MrQgCFY false binding-associated region:?-?(MINT-1366703)|tag:?-?(MINT-5206503) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0422"(immunostaining)