#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O26679 uniprotkb:O26679 intact:EBI-763563|ensemblbacteria:AAB85085 intact:EBI-763563|ensemblbacteria:AAB85085 psi-mi:adhs_metth(display_long)|uniprotkb:aroA'(gene name)|psi-mi:aroA'(display_short)|uniprotkb:MTH_579(locus name) psi-mi:adhs_metth(display_long)|uniprotkb:aroA'(gene name)|psi-mi:aroA'(display_short)|uniprotkb:MTH_579(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763580 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010876218.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR010210(Predicted phospho-2-dehydro-3-deoxyheptonate aldolase)|interpro:IPR002915(Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase)|ensemblbacteria:AAB85085(transcript)|ensemblbacteria:MTH_579(gene)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0016744"(transketolase or transaldolase activity)|go:"GO:0016836"(hydro-lyase activity)|interpro:IPR041720 refseq:WP_010876218.1|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR010210(Predicted phospho-2-dehydro-3-deoxyheptonate aldolase)|interpro:IPR002915(Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase)|ensemblbacteria:AAB85085(transcript)|ensemblbacteria:MTH_579(gene)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0009073"(aromatic amino acid family biosynthetic process)|go:"GO:0016744"(transketolase or transaldolase activity)|go:"GO:0016836"(hydro-lyase activity)|interpro:IPR041720 - - - comment:The Fructose-1-6-bisphosphate aldolase homomeric complex was reported as having 10 subunits|complex-properties:A 300kDa Fructose-1-6-bisphosphate aldolase homomeric complex was detected. Reaction catalsed by complex D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate|caution:annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:996aGKHl1ocBOua06U2z/8RtWNE187420 rogid:996aGKHl1ocBOua06U2z/8RtWNE187420 intact-crc:8A596D3915B12C56|rigid:36v1JLpe7lRGU1m6oFdNHSOWY/c false - - 10 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26729 uniprotkb:O26729 intact:EBI-763597|ensemblbacteria:AAB85138 intact:EBI-763597|ensemblbacteria:AAB85138 psi-mi:o26729_metth(display_long)|uniprotkb:MTH_632(locus name) psi-mi:o26729_metth(display_long)|uniprotkb:MTH_632(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029056|refseq:WP_010876271.1|interpro:IPR027417|ensemblbacteria:AAB85138(transcript)|ensemblbacteria:MTH_632(gene) interpro:IPR029056|refseq:WP_010876271.1|interpro:IPR027417|ensemblbacteria:AAB85138(transcript)|ensemblbacteria:MTH_632(gene) - - - comment:"Putative phosphofructo-(sugar) kinase homomeric complex was reported as having 10 subunits"|complex-properties:"A 700 kDa putative phosphofructo-(sugar) kinase complex was detected."|caution:Annotated by amino acid sequence similarity to characterised proteins in other species. Function unknown.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:VG5zRMv4GWNjspyUMflTtafeb1Y187420 rogid:VG5zRMv4GWNjspyUMflTtafeb1Y187420 intact-crc:4C194F7C559D4F7B|rigid:ZHR4aRl1cAE2uBtrQBplV7QwwDQ false - - 10 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26839 uniprotkb:O26839 intact:EBI-763637|ensemblbacteria:AAB85248 intact:EBI-763637|ensemblbacteria:AAB85248 psi-mi:hem2_metth(display_long)|uniprotkb:Porphobilinogen synthase(gene name synonym)|uniprotkb:hemB(gene name)|psi-mi:hemB(display_short)|uniprotkb:MTH_744(locus name) psi-mi:hem2_metth(display_long)|uniprotkb:Porphobilinogen synthase(gene name synonym)|uniprotkb:hemB(gene name)|psi-mi:hemB(display_short)|uniprotkb:MTH_744(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763646 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR030656|ensemblbacteria:AAB85248(transcript)|ensemblbacteria:MTH_744(gene)|go:"GO:0004655"(porphobilinogen synthase activity)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0046872"(metal ion binding) interpro:IPR001731(Tetrapyrrole biosynthesis, porphobilinogen synthase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR030656|ensemblbacteria:AAB85248(transcript)|ensemblbacteria:MTH_744(gene)|go:"GO:0004655"(porphobilinogen synthase activity)|go:"GO:0006782"(protoporphyrinogen IX biosynthetic process)|go:"GO:0046872"(metal ion binding) - - - comment:Porphobilinogen synthase homomeric complex was reported as having 8 subunits|complex-properties:A 300 kDa porphobilinogen synthase complex was detected.|caution:Annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:ts91OFUm3vUsXAO715fYH53MYic187420 rogid:ts91OFUm3vUsXAO715fYH53MYic187420 intact-crc:56E53BF8819F666F|rigid:/1flW8lm2eIy2OURfqI9mgtclnw false - - 8 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27404 uniprotkb:O27404 intact:EBI-763649|uniprotkb:Q50531|ensemblbacteria:AAB85827 intact:EBI-763649|uniprotkb:Q50531|ensemblbacteria:AAB85827 psi-mi:fpaa_metth(display_long)|uniprotkb:Flavoprotein A(gene name synonym)|uniprotkb:fpaA(gene name)|psi-mi:fpaA(display_short)|uniprotkb:fprA(gene name synonym)|uniprotkb:MTH_1350(locus name)|uniprotkb:FMN protein FprA(gene name synonym) psi-mi:fpaa_metth(display_long)|uniprotkb:Flavoprotein A(gene name synonym)|uniprotkb:fpaA(gene name)|psi-mi:fpaA(display_short)|uniprotkb:fprA(gene name synonym)|uniprotkb:MTH_1350(locus name)|uniprotkb:FMN protein FprA(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029039|refseq:WP_048061030.1|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR016440(Rubredoxin-oxygen oxidoreductase)|interpro:IPR036866|ensemblbacteria:AAB85827(transcript)|ensemblbacteria:MTH_1350(gene)|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0009055"(electron transfer activity) interpro:IPR029039|refseq:WP_048061030.1|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR016440(Rubredoxin-oxygen oxidoreductase)|interpro:IPR036866|ensemblbacteria:AAB85827(transcript)|ensemblbacteria:MTH_1350(gene)|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0009055"(electron transfer activity) - - - comment:Flavoprotein A1 homomeric complex was reported as having 4 subunits|complex-properties:A 150 kDa flavoprotein A1 complex was detected.|caution:Annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:czXO5SRUDiV1sy/s9hUfAgEEvxw187420 rogid:czXO5SRUDiV1sy/s9hUfAgEEvxw187420 intact-crc:DBE64237B750FE67|rigid:9dUZswlPzNChW5k2B41EwfkKkjA false - - 4 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27443 uniprotkb:O27443 intact:EBI-763665|ensemblbacteria:AAB85867 intact:EBI-763665|ensemblbacteria:AAB85867 psi-mi:risb_metth(display_long)|uniprotkb:ribH(gene name)|psi-mi:ribH(display_short)|uniprotkb:MTH_1390(locus name) psi-mi:risb_metth(display_long)|uniprotkb:ribH(gene name)|psi-mi:ribH(display_short)|uniprotkb:MTH_1390(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763674 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002180(6,7-dimethyl-8-ribityllumazine synthase)|refseq:WP_010877002.1|interpro:IPR034964|interpro:IPR036467|ensemblbacteria:AAB85867(transcript)|ensemblbacteria:MTH_1390(gene)|go:"GO:0000906"(6,7-dimethyl-8-ribityllumazine synthase activity)|go:"GO:0009231"(riboflavin biosynthetic process)|go:"GO:0009349"(riboflavin synthase complex) interpro:IPR002180(6,7-dimethyl-8-ribityllumazine synthase)|refseq:WP_010877002.1|interpro:IPR034964|interpro:IPR036467|ensemblbacteria:AAB85867(transcript)|ensemblbacteria:MTH_1390(gene)|go:"GO:0000906"(6,7-dimethyl-8-ribityllumazine synthase activity)|go:"GO:0009231"(riboflavin biosynthetic process)|go:"GO:0009349"(riboflavin synthase complex) - - - comment:Riboflavin synthase beta subunit homomeric complex was reported as having 50 subunits|complex-properties:A 800 kDa Riboflavin synthase beta subunit complex was detected.|caution:Annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Qizvh1VmS9Rq5CVBqKALFUfw/u4187420 rogid:Qizvh1VmS9Rq5CVBqKALFUfw/u4187420 intact-crc:686C7BFFA8603CF9|rigid:72ktCDJ3jEVh2AwOJ5HUOQLIZKA false - - 50 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q50501 uniprotkb:Q50501 intact:EBI-763678|ensemblbacteria:AAB85939 intact:EBI-763678|ensemblbacteria:AAB85939 psi-mi:mtd_metth(display_long)|uniprotkb:Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase(gene name synonym)|uniprotkb:MTH_1464(locus name)|uniprotkb:mtd(gene name)|psi-mi:mtd(display_short) psi-mi:mtd_metth(display_long)|uniprotkb:Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase(gene name synonym)|uniprotkb:MTH_1464(locus name)|uniprotkb:mtd(gene name)|psi-mi:mtd(display_short) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002844(Methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase)|refseq:WP_010877074.1|interpro:IPR036080|ensemblbacteria:AAB85939(transcript)|ensemblbacteria:MTH_1464(gene)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030268"(methylenetetrahydromethanopterin dehydrogenase activity) interpro:IPR002844(Methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase)|refseq:WP_010877074.1|interpro:IPR036080|ensemblbacteria:AAB85939(transcript)|ensemblbacteria:MTH_1464(gene)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030268"(methylenetetrahydromethanopterin dehydrogenase activity) - - - comment:"F420-dependent methylenetetrahydromethanopterin dehydrogenase (MTD) homomeric complex was reported as having 6 subunits"|complex-properties:A 100 kDa flavoprotein A1 complex was detected.|caution:Annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:n/8Ixq0NjpAxcTiFR+FaqXobrWc187420 rogid:n/8Ixq0NjpAxcTiFR+FaqXobrWc187420 intact-crc:7802A69FA8C2B865|rigid:eFJi17y5iRJ9hHDUShiAPOURAfI false - - 6 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27520 uniprotkb:O27520 intact:EBI-763690|ensemblbacteria:AAB85951 intact:EBI-763690|ensemblbacteria:AAB85951 psi-mi:trpb2_metth(display_long)|uniprotkb:trpB2(gene name)|psi-mi:trpB2(display_short)|uniprotkb:MTH_1476(locus name) psi-mi:trpb2_metth(display_long)|uniprotkb:trpB2(gene name)|psi-mi:trpB2(display_short)|uniprotkb:MTH_1476(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006316(Tryptophan synthase, beta chain-like)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR023026|refseq:WP_010877086.1|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR036052|ensemblbacteria:AAB85951(transcript)|ensemblbacteria:MTH_1476(gene)|go:"GO:0004834"(tryptophan synthase activity)|go:"GO:0030170"(pyridoxal phosphate binding) interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR006316(Tryptophan synthase, beta chain-like)|interpro:IPR006653(Tryptophan synthase, beta chain, conserved site)|interpro:IPR023026|refseq:WP_010877086.1|interpro:IPR006654(Tryptophan synthase, beta chain)|interpro:IPR036052|ensemblbacteria:AAB85951(transcript)|ensemblbacteria:MTH_1476(gene)|go:"GO:0004834"(tryptophan synthase activity)|go:"GO:0030170"(pyridoxal phosphate binding) - - - comment:Tryptophan synthase beta chain 2 complex was reported as having 2 subunits|complex-properties:A 100 kDa tryptophan synthase beta chain 2 complex was detected.|caution:Annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:llqVRqscvDBKYfPvB1mXc/7vL9s187420 rogid:llqVRqscvDBKYfPvB1mXc/7vL9s187420 intact-crc:511809063D83FEBE|rigid:fBQw4IkPnAEerK2iiuEbViYEJO4 false - - 2 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27556 uniprotkb:O27556 intact:EBI-763704|ensemblbacteria:AAB85987 intact:EBI-763704|ensemblbacteria:AAB85987 psi-mi:o27556_metth(display_long)|uniprotkb:MTH_1512(locus name) psi-mi:o27556_metth(display_long)|uniprotkb:MTH_1512(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763715 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR010063("Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related")|interpro:IPR004889(H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase)|interpro:IPR024190|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR038182|interpro:IPR036291|ensemblbacteria:AAB85987(transcript)|ensemblbacteria:MTH_1512(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050661"(NADP binding) interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR010063("Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related")|interpro:IPR004889(H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase)|interpro:IPR024190|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR038182|interpro:IPR036291|ensemblbacteria:AAB85987(transcript)|ensemblbacteria:MTH_1512(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0050661"(NADP binding) - - - comment:"H(2)-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase homolog homomeric complex was reported as having 3 subunits"|complex-properties:"A 100 kDa H(2)-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase homolog complex was detected."|caution:Annotated by amino acid sequence similarity to characterised proteins in other species.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:AXpkh+z3cxty0qbx2yx3NyftVmk187420 rogid:AXpkh+z3cxty0qbx2yx3NyftVmk187420 intact-crc:5A449617273CB328|rigid:0v+pzj5o86hs/rhcQCJ8p1pn3n8 false - - 3 0 psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27232 uniprotkb:O27236 intact:EBI-763718|uniprotkb:Q50493|ensemblbacteria:AAB85653 intact:EBI-763726|uniprotkb:Q50489|ensemblbacteria:AAB85657 psi-mi:mcra_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase alpha(gene name synonym)|uniprotkb:mcrA(gene name)|psi-mi:mcrA(display_short)|uniprotkb:MTH_1164(locus name) psi-mi:mcrb_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase beta(gene name synonym)|uniprotkb:mcrB(gene name)|psi-mi:mcrB(display_short)|uniprotkb:MTH_1168(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763742 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016212(Methyl coenzyme M reductase, subunit alpha)|interpro:IPR008924(Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal)|interpro:IPR009047(Methyl-coenzyme M reductase, alpha subunit, C-terminal)|interpro:IPR003183(Methyl-coenzyme M reductase, alpha subunit, N-terminal)|interpro:IPR015811(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1)|interpro:IPR015823(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2)|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|refseq:WP_010876788.1|ensemblbacteria:AAB85653(transcript)|ensemblbacteria:MTH_1164(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) refseq:WP_048061283.1|interpro:IPR008924(Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal)|interpro:IPR015823(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2)|interpro:IPR003179(Methyl-coenzyme M reductase, beta subunit)|interpro:IPR022679|interpro:IPR022680|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|ensemblbacteria:AAB85657(transcript)|ensemblbacteria:MTH_1168(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0015948"(methanogenesis)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) - - - complex-properties:"A 250kDa methyl coenzyme M reductase 1 complex was detected. Reaction catalsed by complex reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide."|comment:There are two MCR complexes in this bacteria. MCR II is expressed in the early growth phase. Late growth cells contains mostly MCR I.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:t0brIcx+9Qpja5hdnP97itIB5QI187420 rogid:gyXGONcp8TsvX8Gx1fxeFGUqii4187420 intact-crc:B122E3A4589CDDBC|rigid:La+aydWu+I5QOwd1gHf6Se3EQJE false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27232 uniprotkb:O27233 intact:EBI-763718|uniprotkb:Q50493|ensemblbacteria:AAB85653 intact:EBI-763733|uniprotkb:Q50492|ensemblbacteria:AAB85654 psi-mi:mcra_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase alpha(gene name synonym)|uniprotkb:mcrA(gene name)|psi-mi:mcrA(display_short)|uniprotkb:MTH_1164(locus name) psi-mi:mcrg_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase gamma(gene name synonym)|uniprotkb:mcrG(gene name)|psi-mi:mcrG(display_short)|uniprotkb:MTH_1165(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763742 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016212(Methyl coenzyme M reductase, subunit alpha)|interpro:IPR008924(Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal)|interpro:IPR009047(Methyl-coenzyme M reductase, alpha subunit, C-terminal)|interpro:IPR003183(Methyl-coenzyme M reductase, alpha subunit, N-terminal)|interpro:IPR015811(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1)|interpro:IPR015823(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2)|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|refseq:WP_010876788.1|ensemblbacteria:AAB85653(transcript)|ensemblbacteria:MTH_1164(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) refseq:WP_048060982.1|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|interpro:IPR003178(Methyl-coenzyme M reductase, gamma subunit)|interpro:IPR036994|ensemblbacteria:AAB85654(transcript)|ensemblbacteria:MTH_1165(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0015948"(methanogenesis)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) - - - complex-properties:"A 250kDa methyl coenzyme M reductase 1 complex was detected. Reaction catalsed by complex reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide."|comment:There are two MCR complexes in this bacteria. MCR II is expressed in the early growth phase. Late growth cells contains mostly MCR I.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:t0brIcx+9Qpja5hdnP97itIB5QI187420 rogid:a9Q6rznhr2yWOQnmvs5jihmYTx4187420 intact-crc:B122E3A4589CDDBC|rigid:La+aydWu+I5QOwd1gHf6Se3EQJE false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P21110 uniprotkb:P21111 intact:EBI-763747|uniprotkb:O27201|uniprotkb:Q50487|ensemblbacteria:AAB85618 intact:EBI-763764|uniprotkb:O27204|ensemblbacteria:AAB85621 psi-mi:mcrx_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase alpha(gene name synonym)|uniprotkb:mrtA(gene name)|psi-mi:mrtA(display_short)|uniprotkb:MTH_1129(locus name) psi-mi:mcry_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase beta(gene name synonym)|uniprotkb:mrtB(gene name)|psi-mi:mrtB(display_short)|uniprotkb:MTH_1132(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763773 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016212(Methyl coenzyme M reductase, subunit alpha)|interpro:IPR008924(Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal)|interpro:IPR009047(Methyl-coenzyme M reductase, alpha subunit, C-terminal)|interpro:IPR003183(Methyl-coenzyme M reductase, alpha subunit, N-terminal)|interpro:IPR015811(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1)|interpro:IPR015823(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2)|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|refseq:WP_010876753.1|ensemblbacteria:AAB85618(transcript)|ensemblbacteria:MTH_1129(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) refseq:WP_048060974.1|interpro:IPR008924(Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal)|interpro:IPR015823(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2)|interpro:IPR003179(Methyl-coenzyme M reductase, beta subunit)|interpro:IPR022679|interpro:IPR022680|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|ensemblbacteria:AAB85621(transcript)|ensemblbacteria:MTH_1132(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) - - - complex-properties:"A 250kDa methyl coenzyme M reductase II complex was detected. Reaction catalsed by complex reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide."|comment:There are two MCR complexes in this bacteria. MCR II is expressed in the early growth phase. Late growth cells contains mostly MCR I.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:kLn4WZmNRtvXHmo52Q83cu9f49E187420 rogid:Z20x5CAW9DFn9GWCDsZzPnb5x+E187420 intact-crc:715EFB2CC3E4F2E5|rigid:g00ckYMrt4P8MpHvswwU+3fAus8 false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P21110 uniprotkb:P21112 intact:EBI-763747|uniprotkb:O27201|uniprotkb:Q50487|ensemblbacteria:AAB85618 intact:EBI-763756|uniprotkb:O27202|uniprotkb:Q50486|ensemblbacteria:AAB85619 psi-mi:mcrx_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase alpha(gene name synonym)|uniprotkb:mrtA(gene name)|psi-mi:mrtA(display_short)|uniprotkb:MTH_1129(locus name) psi-mi:mcrz_metth(display_long)|uniprotkb:Coenzyme-B sulfoethylthiotransferase gamma(gene name synonym)|uniprotkb:mrtG(gene name)|psi-mi:mrtG(display_short)|uniprotkb:MTH_1130(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763773 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR016212(Methyl coenzyme M reductase, subunit alpha)|interpro:IPR008924(Methyl-coenzyme M reductase, alpha/beta subunit, C-terminal)|interpro:IPR009047(Methyl-coenzyme M reductase, alpha subunit, C-terminal)|interpro:IPR003183(Methyl-coenzyme M reductase, alpha subunit, N-terminal)|interpro:IPR015811(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 1)|interpro:IPR015823(Methyl-coenzyme M reductase, alpha subunit, N-terminal subdomain 2)|interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|refseq:WP_010876753.1|ensemblbacteria:AAB85618(transcript)|ensemblbacteria:MTH_1129(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) interpro:IPR009024(Methyl-coenzyme M reductase, ferredoxin-like fold)|interpro:IPR003178(Methyl-coenzyme M reductase, gamma subunit)|interpro:IPR036994|ensemblbacteria:AAB85619(transcript)|ensemblbacteria:MTH_1130(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0050524"(coenzyme-B sulfoethylthiotransferase activity) - - - complex-properties:"A 250kDa methyl coenzyme M reductase II complex was detected. Reaction catalsed by complex reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide."|comment:There are two MCR complexes in this bacteria. MCR II is expressed in the early growth phase. Late growth cells contains mostly MCR I.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:kLn4WZmNRtvXHmo52Q83cu9f49E187420 rogid:UPt/NouT+Owzxio5U8VbmvdVz9s187420 intact-crc:715EFB2CC3E4F2E5|rigid:g00ckYMrt4P8MpHvswwU+3fAus8 false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27600 uniprotkb:O27599 intact:EBI-763785|ensemblbacteria:AAB86032 intact:EBI-763780|ensemblbacteria:AAB86031 psi-mi:fwdc_metth(display_long)|uniprotkb:Tungsten-containing formylmethanofuran dehydrogenase II subunit C(gene name synonym)|uniprotkb:fwdC(gene name)|psi-mi:fwdC(display_short)|uniprotkb:MTH_1558(locus name) psi-mi:o27599_metth(display_long)|uniprotkb:MTH_1557(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763800 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017550(Formylmethanofuran dehydrogenase subunit C)|refseq:WP_010877167.1|interpro:IPR036485|ensemblbacteria:AAB86032(transcript)|ensemblbacteria:MTH_1558(gene)|go:"GO:0018493"(formylmethanofuran dehydrogenase activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0019386"(methanogenesis, from carbon dioxide) refseq:WP_010877166.1|interpro:IPR013108(Amidohydrolase 3)|interpro:IPR012027(Formylmethanofuran dehydrogenase, subunit A)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|ensemblbacteria:AAB86031(transcript)|ensemblbacteria:MTH_1557(gene)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds") - - - complex-properties:"A 100kDa tungsten-dependent formylmethanofuran dehydrogenase complex was detected. Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidise formylmethanofuran. This enzyme is oxygen-labile"|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Xhuv7QZpI6QJGO32s2VRSMUIkbY187420 rogid:qmLhtamQB5P206KEFGufj/lM15k187420 intact-crc:DAF1DCBF5FBCCACD|rigid:sMQoW2kNm2v0G6jtRS/lI8EVFWk false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27600 uniprotkb:O27601 intact:EBI-763785|ensemblbacteria:AAB86032 intact:EBI-763792|ensemblbacteria:AAB86033 psi-mi:fwdc_metth(display_long)|uniprotkb:Tungsten-containing formylmethanofuran dehydrogenase II subunit C(gene name synonym)|uniprotkb:fwdC(gene name)|psi-mi:fwdC(display_short)|uniprotkb:MTH_1558(locus name) psi-mi:o27601_metth(display_long)|uniprotkb:MTH_1559(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763800 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017550(Formylmethanofuran dehydrogenase subunit C)|refseq:WP_010877167.1|interpro:IPR036485|ensemblbacteria:AAB86032(transcript)|ensemblbacteria:MTH_1558(gene)|go:"GO:0018493"(formylmethanofuran dehydrogenase activity)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0019386"(methanogenesis, from carbon dioxide) interpro:IPR016457(Formylmethanofuran dehydrogenase, subunit B)|interpro:IPR006656(Molybdopterin oxidoreductase)|ensemblbacteria:AAB86033(transcript)|ensemblbacteria:MTH_1559(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0018493"(formylmethanofuran dehydrogenase activity) - - - complex-properties:"A 100kDa tungsten-dependent formylmethanofuran dehydrogenase complex was detected. Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidise formylmethanofuran. This enzyme is oxygen-labile"|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Xhuv7QZpI6QJGO32s2VRSMUIkbY187420 rogid:VaarPlg9sgcwAgvFYTR6LLuxSks187420 intact-crc:DAF1DCBF5FBCCACD|rigid:sMQoW2kNm2v0G6jtRS/lI8EVFWk false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27227 uniprotkb:O27229 intact:EBI-763825|ensemblbacteria:AAB85648 intact:EBI-763831|ensemblbacteria:AAB85650 psi-mi:mtra1_metth(display_long)|uniprotkb:mtrA1(gene name)|psi-mi:mtrA1(display_short)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A 1(gene name synonym)|uniprotkb:MTH_1159(locus name) psi-mi:mtrc_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C(gene name synonym)|uniprotkb:mtrC(gene name)|psi-mi:mtrC(display_short)|uniprotkb:MTH_1161(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763851 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005778(Tetrahydromethanopterin S-methyltransferase, subunit A)|interpro:IPR030688|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|refseq:WP_010876783.1|ensemblbacteria:AAB85648(transcript)|ensemblbacteria:MTH_1159(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0050897"(cobalt ion binding) refseq:WP_010876785.1|interpro:IPR005865(Tetrahydromethanopterin S-methyltransferase, subunit C)|ensemblbacteria:AAB85650(transcript)|ensemblbacteria:MTH_1161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) - - - complex-properties:A 900kDa methyltransferase complex was detected. The complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:OkTqgn/esqb+0spwNU/BNHtDEwA187420 rogid:GatuOqnzmKd2UdPN37LP+Ur+7yA187420 intact-crc:4B6D8D0766556336|rigid:R8ZbkOP/1IB9VL+V41c4JJF7geo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27227 uniprotkb:O27230 intact:EBI-763825|ensemblbacteria:AAB85648 intact:EBI-763837|ensemblbacteria:AAB85651 psi-mi:mtra1_metth(display_long)|uniprotkb:mtrA1(gene name)|psi-mi:mtrA1(display_short)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A 1(gene name synonym)|uniprotkb:MTH_1159(locus name) psi-mi:mtrd_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D(gene name synonym)|uniprotkb:mtrD(gene name)|psi-mi:mtrD(display_short)|uniprotkb:MTH_1162(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763851 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005778(Tetrahydromethanopterin S-methyltransferase, subunit A)|interpro:IPR030688|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|refseq:WP_010876783.1|ensemblbacteria:AAB85648(transcript)|ensemblbacteria:MTH_1159(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0050897"(cobalt ion binding) interpro:IPR005779(Tetrahydromethanopterin S-methyltransferase, subunit D)|ensemblbacteria:AAB85651(transcript)|ensemblbacteria:MTH_1162(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:WP_010876786.1 - - - complex-properties:A 900kDa methyltransferase complex was detected. The complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:OkTqgn/esqb+0spwNU/BNHtDEwA187420 rogid:ttWtB3iR+6n6UOcHlkuYd2Z1v2I187420 intact-crc:4B6D8D0766556336|rigid:R8ZbkOP/1IB9VL+V41c4JJF7geo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27227 uniprotkb:O27231 intact:EBI-763825|ensemblbacteria:AAB85648 intact:EBI-763843|uniprotkb:Q59582|ensemblbacteria:AAB85652 psi-mi:mtra1_metth(display_long)|uniprotkb:mtrA1(gene name)|psi-mi:mtrA1(display_short)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A 1(gene name synonym)|uniprotkb:MTH_1159(locus name) psi-mi:mtre_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E(gene name synonym)|uniprotkb:mtrE(gene name)|psi-mi:mtrE(display_short)|uniprotkb:MTH_1163(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763851 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005778(Tetrahydromethanopterin S-methyltransferase, subunit A)|interpro:IPR030688|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|refseq:WP_010876783.1|ensemblbacteria:AAB85648(transcript)|ensemblbacteria:MTH_1159(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0050897"(cobalt ion binding) interpro:IPR005780(Tetrahydromethanopterin S-methyltransferase, subunit E)|ensemblbacteria:AAB85652(transcript)|ensemblbacteria:MTH_1163(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:WP_010876787.1 - - - complex-properties:A 900kDa methyltransferase complex was detected. The complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:OkTqgn/esqb+0spwNU/BNHtDEwA187420 rogid:C/eTJ1Jzn+svHNqD/FIMkQDxtzQ187420 intact-crc:4B6D8D0766556336|rigid:R8ZbkOP/1IB9VL+V41c4JJF7geo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27227 uniprotkb:O27226 intact:EBI-763825|ensemblbacteria:AAB85648 intact:EBI-763819|ensemblbacteria:AAB85647 psi-mi:mtra1_metth(display_long)|uniprotkb:mtrA1(gene name)|psi-mi:mtrA1(display_short)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A 1(gene name synonym)|uniprotkb:MTH_1159(locus name) psi-mi:mtrf_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit F(gene name synonym)|uniprotkb:mtrF(gene name)|psi-mi:mtrF(display_short)|uniprotkb:MTH_1158(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763851 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005778(Tetrahydromethanopterin S-methyltransferase, subunit A)|interpro:IPR030688|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|refseq:WP_010876783.1|ensemblbacteria:AAB85648(transcript)|ensemblbacteria:MTH_1159(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0050897"(cobalt ion binding) refseq:WP_010876782.1|interpro:IPR011307(Tetrahydromethanopterin S-methyltransferase, subunit F)|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|ensemblbacteria:AAB85647(transcript)|ensemblbacteria:MTH_1158(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) - - - complex-properties:A 900kDa methyltransferase complex was detected. The complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:OkTqgn/esqb+0spwNU/BNHtDEwA187420 rogid:63TMTayAMhUzaaU1UyVeyu+xhF8187420 intact-crc:4B6D8D0766556336|rigid:R8ZbkOP/1IB9VL+V41c4JJF7geo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27227 uniprotkb:O27225 intact:EBI-763825|ensemblbacteria:AAB85648 intact:EBI-763813|ensemblbacteria:AAB85646 psi-mi:mtra1_metth(display_long)|uniprotkb:mtrA1(gene name)|psi-mi:mtrA1(display_short)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A 1(gene name synonym)|uniprotkb:MTH_1159(locus name) psi-mi:mtrg_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit G(gene name synonym)|uniprotkb:mtrG(gene name)|psi-mi:mtrG(display_short)|uniprotkb:MTH_1157(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763851 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005778(Tetrahydromethanopterin S-methyltransferase, subunit A)|interpro:IPR030688|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|refseq:WP_010876783.1|ensemblbacteria:AAB85648(transcript)|ensemblbacteria:MTH_1159(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0050897"(cobalt ion binding) refseq:WP_010876781.1|interpro:IPR005866(Tetrahydromethanopterin S-methyltransferase, subunit G)|ensemblbacteria:AAB85646(transcript)|ensemblbacteria:MTH_1157(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) - - - complex-properties:A 900kDa methyltransferase complex was detected. The complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:OkTqgn/esqb+0spwNU/BNHtDEwA187420 rogid:+OLyl8KLmEqaZ3FZrAuc2pP4xu4187420 intact-crc:4B6D8D0766556336|rigid:R8ZbkOP/1IB9VL+V41c4JJF7geo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27227 uniprotkb:O27224 intact:EBI-763825|ensemblbacteria:AAB85648 intact:EBI-763807|ensemblbacteria:AAB85645 psi-mi:mtra1_metth(display_long)|uniprotkb:mtrA1(gene name)|psi-mi:mtrA1(display_short)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A 1(gene name synonym)|uniprotkb:MTH_1159(locus name) psi-mi:mtrh_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit H(gene name synonym)|uniprotkb:mtrH(gene name)|psi-mi:mtrH(display_short)|uniprotkb:MTH_1156(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763851 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005778(Tetrahydromethanopterin S-methyltransferase, subunit A)|interpro:IPR030688|interpro:IPR013347(Tetrahydromethanopterin S-methyltransferase, F subunit)|refseq:WP_010876783.1|ensemblbacteria:AAB85648(transcript)|ensemblbacteria:MTH_1159(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0050897"(cobalt ion binding) interpro:IPR028342|refseq:WP_010876780.1|interpro:IPR011005(Dihydropteroate synthase-like)|interpro:IPR023467|ensemblbacteria:AAB85645(transcript)|ensemblbacteria:MTH_1156(gene)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) - - - complex-properties:A 900kDa methyltransferase complex was detected. The complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:OkTqgn/esqb+0spwNU/BNHtDEwA187420 rogid:hXYdHwk+ybPyY5JOLZrE8/Hc6B8187420 intact-crc:4B6D8D0766556336|rigid:R8ZbkOP/1IB9VL+V41c4JJF7geo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27434 uniprotkb:O27907 intact:EBI-763862|ensemblbacteria:AAB85858 intact:EBI-763876|ensemblbacteria:AAB86345 psi-mi:hdra_metth(display_long)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTH_1381(locus name) psi-mi:hdrb_metth(display_long)|uniprotkb:hdrB(gene name)|psi-mi:hdrB(display_short)|uniprotkb:CoB--CoM heterodisulfide reductase subunit B(gene name synonym)|uniprotkb:MTH_1879(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763883 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_048061038.1|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|ensemblbacteria:AAB85858(transcript)|ensemblbacteria:MTH_1381(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR017678(CoB/CoM heterodisulphide reductase, subunit B)|interpro:IPR004017(Cysteine-rich region, CCG)|refseq:WP_010877481.1|ensemblbacteria:AAB86345(transcript)|ensemblbacteria:MTH_1879(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity) - - - complex-properties:"A 300kDa and a 400kDa heterodisulphide reductase complex was detected. a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). Subunit A (O27434) may act as the catalytic subunit (By similarity). Cells cultured under MCR I conditions (N medium (15) at 65 �C with a gas flow of 2.0 liters/min of 80% H2, 20% CO2 (v/v) and harvested at an optical density at 600 nm of 5) had a 3-fold increase in the complex than cells grown under MCR II conditions (55 �C with a gas flow of 5.0 liters/min of 80% H2, 20% CO2 (v/v) and harvested at an optical density at 600 nm of 1.8)."|comment:Auhors state that the higher molecular weight complex detected represented an association between of the heterosulphide reductase and methylviologen-reducing hydrogenase complexes.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:fqHUL/4XzT5fxCEQlkKBKmPBM5s187420 rogid:kvDthVK0PsZm8Y8dcR5WuA7jwfA187420 intact-crc:FB389BCAFD97EF16|rigid:macJKBiDYREjkYH6f6y0BwtmrnI false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27434 uniprotkb:O27906 intact:EBI-763862|ensemblbacteria:AAB85858 intact:EBI-763869|ensemblbacteria:AAB86344 psi-mi:hdra_metth(display_long)|uniprotkb:hdrA(gene name)|psi-mi:hdrA(display_short)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit A(gene name synonym)|uniprotkb:MTH_1381(locus name) psi-mi:hdrc_metth(display_long)|uniprotkb:hdrC(gene name)|psi-mi:hdrC(display_short)|uniprotkb:CoB--CoM heterodisulfide reductase iron-sulfur subunit C(gene name synonym)|uniprotkb:MTH_1878(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763883 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_048061038.1|interpro:IPR017896|interpro:IPR017900|interpro:IPR023753|interpro:IPR036188|interpro:IPR039650|ensemblbacteria:AAB85858(transcript)|ensemblbacteria:MTH_1381(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR017896|interpro:IPR017900|interpro:IPR017680(CoB--CoM heterodisulphide reductase, subunit C)|interpro:IPR009051(Alpha-helical ferredoxin)|refseq:WP_052261191.1|ensemblbacteria:AAB86344(transcript)|ensemblbacteria:MTH_1878(gene)|go:"GO:0015948"(methanogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051912"(CoB--CoM heterodisulfide reductase activity) - - - complex-properties:"A 300kDa and a 400kDa heterodisulphide reductase complex was detected. a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). Subunit A (O27434) may act as the catalytic subunit (By similarity). Cells cultured under MCR I conditions (N medium (15) at 65 �C with a gas flow of 2.0 liters/min of 80% H2, 20% CO2 (v/v) and harvested at an optical density at 600 nm of 5) had a 3-fold increase in the complex than cells grown under MCR II conditions (55 �C with a gas flow of 5.0 liters/min of 80% H2, 20% CO2 (v/v) and harvested at an optical density at 600 nm of 1.8)."|comment:Auhors state that the higher molecular weight complex detected represented an association between of the heterosulphide reductase and methylviologen-reducing hydrogenase complexes.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:fqHUL/4XzT5fxCEQlkKBKmPBM5s187420 rogid:gz41oveMCixs5pcHRRJiczZTo+k187420 intact-crc:FB389BCAFD97EF16|rigid:macJKBiDYREjkYH6f6y0BwtmrnI false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q50783 uniprotkb:Q50781 intact:EBI-763890|uniprotkb:O27206|ensemblbacteria:AAB85623 intact:EBI-763904|uniprotkb:O27208|ensemblbacteria:AAB85625 psi-mi:mvha_metth(display_long)|uniprotkb:Methyl viologen-reducing hydrogenase subunit alpha(gene name synonym)|uniprotkb:mvhA(gene name)|psi-mi:mvhA(display_short)|uniprotkb:MTH_1134(locus name) psi-mi:mvhd_metth(display_long)|uniprotkb:Methyl viologen-reducing hydrogenase subunit delta(gene name synonym)|uniprotkb:mvhD(gene name)|psi-mi:mvhD(display_short)|uniprotkb:MTH_1136(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763913 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029014|refseq:WP_010876758.1|interpro:IPR001501(Nickel-dependent hydrogenase, large subunit)|interpro:IPR018194|ensemblbacteria:AAB85623(transcript)|ensemblbacteria:MTH_1134(gene)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0016151"(nickel cation binding) interpro:IPR003813(Methyl-viologen-reducing hydrogenase, delta subunit)|refseq:WP_010876760.1|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|ensemblbacteria:AAB85625(transcript)|ensemblbacteria:MTH_1136(gene) - - - complex-properties:"A 100 kDa Methylviologen-reducing hydrogenase complex was detected. A complex that provides reducing equivalents for heterodisulfide reductase. MvhD may form the contact site to heterodisulfide reductase (By similarity)."|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:3y8jvQzBfoFPtkdAS0vykgNuc0w187420 rogid:APmjk5Pmyo934lx0gabaEamNzEA187420 intact-crc:5ABB9553D6994839|rigid:XsmjUSOear5UCUAJQUteBjj+cr4 false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:Q50783 uniprotkb:Q50782 intact:EBI-763890|uniprotkb:O27206|ensemblbacteria:AAB85623 intact:EBI-763897|uniprotkb:O27207|ensemblbacteria:AAB85624 psi-mi:mvha_metth(display_long)|uniprotkb:Methyl viologen-reducing hydrogenase subunit alpha(gene name synonym)|uniprotkb:mvhA(gene name)|psi-mi:mvhA(display_short)|uniprotkb:MTH_1134(locus name) psi-mi:mvhg_metth(display_long)|uniprotkb:Methyl viologen-reducing hydrogenase subunit gamma(gene name synonym)|uniprotkb:mvhG(gene name)|psi-mi:mvhG(display_short)|uniprotkb:MTH_1135(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763913 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029014|refseq:WP_010876758.1|interpro:IPR001501(Nickel-dependent hydrogenase, large subunit)|interpro:IPR018194|ensemblbacteria:AAB85623(transcript)|ensemblbacteria:MTH_1134(gene)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0016151"(nickel cation binding) interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|refseq:WP_010876759.1|interpro:IPR037024|ensemblbacteria:AAB85624(transcript)|ensemblbacteria:MTH_1135(gene)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051536"(iron-sulfur cluster binding) - - - complex-properties:"A 100 kDa Methylviologen-reducing hydrogenase complex was detected. A complex that provides reducing equivalents for heterodisulfide reductase. MvhD may form the contact site to heterodisulfide reductase (By similarity)."|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:3y8jvQzBfoFPtkdAS0vykgNuc0w187420 rogid:dn3toI8IhsYJlxaaoWEs99N28Lk187420 intact-crc:5ABB9553D6994839|rigid:XsmjUSOear5UCUAJQUteBjj+cr4 false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P19496 uniprotkb:P19499 intact:EBI-763955|ensemblbacteria:AAB85780 intact:EBI-763939|uniprotkb:O27356|ensemblbacteria:AAB85777 psi-mi:frha_metth(display_long)|uniprotkb:8-hydroxy-5-deazaflavin-reducing hydrogenase subunit alpha(gene name synonym)|uniprotkb:frhA(gene name)|psi-mi:frhA(display_short)|uniprotkb:MTH_1300(locus name) psi-mi:frhb_metth(display_long)|uniprotkb:8-hydroxy-5-deazaflavin-reducing hydrogenase subunit beta(gene name synonym)|uniprotkb:frhB(gene name)|psi-mi:frhB(display_short)|uniprotkb:MTH_1297(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763962 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029014|refseq:WP_048061018.1|interpro:IPR017682(Coenzyme F420 hydrogenase, subunit alpha)|interpro:IPR001501(Nickel-dependent hydrogenase, large subunit)|interpro:IPR018194|ensemblbacteria:AAB85780(transcript)|ensemblbacteria:MTH_1300(gene)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0016151"(nickel cation binding)|go:"GO:0050454"(coenzyme F420 hydrogenase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051536"(iron-sulfur cluster binding) interpro:IPR007516(Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal)|interpro:IPR017679(Coenzyme F420 hydrogenase, subunit beta)|interpro:IPR007525(Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal)|refseq:WP_010876912.1|ensemblbacteria:AAB85777(transcript)|ensemblbacteria:MTH_1297(gene)|go:"GO:0016151"(nickel cation binding)|go:"GO:0050454"(coenzyme F420 hydrogenase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051536"(iron-sulfur cluster binding) - - - complex-properties:A 1000 kDa F420-reducing hydrogenase complex was detected. A complex that reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:d963xfMh+tkqocymjE+6bVShKmE187420 rogid:gkb+9/8lgKJMtjba2nmcR53Gzeg187420 intact-crc:8012BE8870581B05|rigid:8GGFLHktS8qeMKwV76hZcjrILMs false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P19496 uniprotkb:P19498 intact:EBI-763955|ensemblbacteria:AAB85780 intact:EBI-763947|uniprotkb:O27357|ensemblbacteria:AAB85778 psi-mi:frha_metth(display_long)|uniprotkb:8-hydroxy-5-deazaflavin-reducing hydrogenase subunit alpha(gene name synonym)|uniprotkb:frhA(gene name)|psi-mi:frhA(display_short)|uniprotkb:MTH_1300(locus name) psi-mi:frhg_metth(display_long)|uniprotkb:8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma(gene name synonym)|uniprotkb:frhG(gene name)|psi-mi:frhG(display_short)|uniprotkb:MTH_1298(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-763962 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029014|refseq:WP_048061018.1|interpro:IPR017682(Coenzyme F420 hydrogenase, subunit alpha)|interpro:IPR001501(Nickel-dependent hydrogenase, large subunit)|interpro:IPR018194|ensemblbacteria:AAB85780(transcript)|ensemblbacteria:MTH_1300(gene)|go:"GO:0008901"(ferredoxin hydrogenase activity)|go:"GO:0016151"(nickel cation binding)|go:"GO:0050454"(coenzyme F420 hydrogenase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051536"(iron-sulfur cluster binding) interpro:IPR017896|interpro:IPR017900|interpro:IPR017681(Coenzyme F420 hydrogenase, subunit gamma)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR037024|ensemblbacteria:AAB85778(transcript)|ensemblbacteria:MTH_1298(gene)|go:"GO:0016151"(nickel cation binding)|go:"GO:0050454"(coenzyme F420 hydrogenase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) - - - complex-properties:A 1000 kDa F420-reducing hydrogenase complex was detected. A complex that reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:d963xfMh+tkqocymjE+6bVShKmE187420 rogid:kA7mFC+Xlz5zUGrAXEoa6K9DUNQ187420 intact-crc:8012BE8870581B05|rigid:8GGFLHktS8qeMKwV76hZcjrILMs false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27036 uniprotkb:O27035 intact:EBI-763984|ensemblbacteria:AAB85451 intact:EBI-763975|ensemblbacteria:AAB85450 psi-mi:vata_metth(display_long)|uniprotkb:atpA(gene name)|psi-mi:atpA(display_short)|uniprotkb:MTH_955(locus name)|uniprotkb:V-ATPase subunit A(gene name synonym) psi-mi:vatb_metth(display_long)|uniprotkb:atpB(gene name)|psi-mi:atpB(display_short)|uniprotkb:MTH_954(locus name)|uniprotkb:V-ATPase subunit B(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764001 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020003|interpro:IPR005726(ATPase, A1 complex, alpha subunit)|interpro:IPR023366|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR024034|interpro:IPR022878|refseq:WP_010876586.1|interpro:IPR031686|interpro:IPR027417|interpro:IPR036121|ensemblbacteria:AAB85451(transcript)|ensemblbacteria:MTH_955(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) interpro:IPR020003|interpro:IPR005724(ATPase, A1 complex, beta subunit)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR022879|refseq:WP_013296141.1|interpro:IPR027417|interpro:IPR036121|ensemblbacteria:AAB85450(transcript)|ensemblbacteria:MTH_954(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) - - - complex-properties:A 400 kDa subcomplex of the ATP synthase complex was detected. A complex that produces ATP from ADP in the presence of a proton gradient across the membrane.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:NQ+OQ5Sw/QphmCpCDOPPbKIFq7w187420 rogid:YRAx5jtOnMRpZUPXn5635sZSwkQ187420 intact-crc:89F009B578085E95|rigid:+Fa+58ZdrUaUFAk/ZEZi2OiUKNI false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27036 uniprotkb:O27034 intact:EBI-763984|ensemblbacteria:AAB85451 intact:EBI-763969|ensemblbacteria:AAB85449 psi-mi:vata_metth(display_long)|uniprotkb:atpA(gene name)|psi-mi:atpA(display_short)|uniprotkb:MTH_955(locus name)|uniprotkb:V-ATPase subunit A(gene name synonym) psi-mi:vatd_metth(display_long)|uniprotkb:atpD(gene name)|psi-mi:atpD(display_short)|uniprotkb:MTH_953(locus name)|uniprotkb:V-ATPase subunit D(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764001 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020003|interpro:IPR005726(ATPase, A1 complex, alpha subunit)|interpro:IPR023366|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR024034|interpro:IPR022878|refseq:WP_010876586.1|interpro:IPR031686|interpro:IPR027417|interpro:IPR036121|ensemblbacteria:AAB85451(transcript)|ensemblbacteria:MTH_955(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) interpro:IPR002699(ATPase, V1/A1 complex, subunit D)|refseq:WP_010876584.1|ensemblbacteria:AAB85449(transcript)|ensemblbacteria:MTH_953(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) - - - complex-properties:A 400 kDa subcomplex of the ATP synthase complex was detected. A complex that produces ATP from ADP in the presence of a proton gradient across the membrane.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:NQ+OQ5Sw/QphmCpCDOPPbKIFq7w187420 rogid:yTYmw7ZiHVb8+rQvSbc6/Ky9TAg187420 intact-crc:89F009B578085E95|rigid:+Fa+58ZdrUaUFAk/ZEZi2OiUKNI false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27036 uniprotkb:O27037 intact:EBI-763984|ensemblbacteria:AAB85451 intact:EBI-763993|ensemblbacteria:AAB85452 psi-mi:vata_metth(display_long)|uniprotkb:atpA(gene name)|psi-mi:atpA(display_short)|uniprotkb:MTH_955(locus name)|uniprotkb:V-ATPase subunit A(gene name synonym) psi-mi:vatf_metth(display_long)|uniprotkb:atpF(gene name)|psi-mi:atpF(display_short)|uniprotkb:MTH_956(locus name)|uniprotkb:V-ATPase subunit F(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764001 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020003|interpro:IPR005726(ATPase, A1 complex, alpha subunit)|interpro:IPR023366|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR024034|interpro:IPR022878|refseq:WP_010876586.1|interpro:IPR031686|interpro:IPR027417|interpro:IPR036121|ensemblbacteria:AAB85451(transcript)|ensemblbacteria:MTH_955(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) interpro:IPR022944|interpro:IPR008218(ATPase, V1/A1 complex, subunit F)|refseq:WP_010876587.1|interpro:IPR036906|ensemblbacteria:AAB85452(transcript)|ensemblbacteria:MTH_956(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism) - - - complex-properties:A 400 kDa subcomplex of the ATP synthase complex was detected. A complex that produces ATP from ADP in the presence of a proton gradient across the membrane.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:NQ+OQ5Sw/QphmCpCDOPPbKIFq7w187420 rogid:6uccV6U1C3DZLTBm8J8b0EzEd00187420 intact-crc:89F009B578085E95|rigid:+Fa+58ZdrUaUFAk/ZEZi2OiUKNI false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27042 uniprotkb:O27038 intact:EBI-764027|ensemblbacteria:AAB85457 intact:EBI-764009|ensemblbacteria:AAB85453 psi-mi:o27042_metth(display_long)|uniprotkb:MTH_961(locus name) psi-mi:vatc_metth(display_long)|uniprotkb:atpC(gene name)|psi-mi:atpC(display_short)|uniprotkb:MTH_957(locus name)|uniprotkb:V-ATPase subunit C(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764033 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028987|interpro:IPR014275(ATPase, A1A0, subunit H)|ensemblbacteria:AAB85457(transcript)|ensemblbacteria:MTH_961(gene) interpro:IPR014272(ATPase, A1 complex, subunit C archaea)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|refseq:WP_010876588.1|interpro:IPR035067|interpro:IPR036079|ensemblbacteria:AAB85453(transcript)|ensemblbacteria:MTH_957(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR044911 - - - complex-properties:A 600 kDa subcomplex of the ATP synthase complex was detected. A complex that produces ATP from ADP in the presence of a proton gradient across the membrane.|comment:o27042 is annotated as A0 subcomplex ATP synthase subunit H by authors|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Pdv954v+QJ+c7sR6azQ2Lnbz248187420 rogid:zCM9qB52SphcE58BMmSlIZ3k8/M187420 intact-crc:BF7B8F96D345347C|rigid:XQPOqPzFb1e5pdIQRkkfmWfnBzQ false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27042 uniprotkb:O27039 intact:EBI-764027|ensemblbacteria:AAB85457 intact:EBI-764015|ensemblbacteria:AAB85454 psi-mi:o27042_metth(display_long)|uniprotkb:MTH_961(locus name) psi-mi:vate_metth(display_long)|uniprotkb:atpE(gene name)|psi-mi:atpE(display_short)|uniprotkb:MTH_958(locus name)|uniprotkb:V-ATPase subunit E(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764033 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028987|interpro:IPR014275(ATPase, A1A0, subunit H)|ensemblbacteria:AAB85457(transcript)|ensemblbacteria:MTH_961(gene) interpro:IPR028987|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|refseq:WP_010876589.1|interpro:IPR038495|ensemblbacteria:AAB85454(transcript)|ensemblbacteria:MTH_958(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033178"(proton-transporting two-sector ATPase complex, catalytic domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism) - - - complex-properties:A 600 kDa subcomplex of the ATP synthase complex was detected. A complex that produces ATP from ADP in the presence of a proton gradient across the membrane.|comment:o27042 is annotated as A0 subcomplex ATP synthase subunit H by authors|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Pdv954v+QJ+c7sR6azQ2Lnbz248187420 rogid:tCZyKV8ZoJTmpcnYwMPDFto0EZo187420 intact-crc:BF7B8F96D345347C|rigid:XQPOqPzFb1e5pdIQRkkfmWfnBzQ false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27042 uniprotkb:O27041 intact:EBI-764027|ensemblbacteria:AAB85457 intact:EBI-764021|ensemblbacteria:AAB85456 psi-mi:o27042_metth(display_long)|uniprotkb:MTH_961(locus name) psi-mi:vati_metth(display_long)|uniprotkb:atpI(gene name)|psi-mi:atpI(display_short)|uniprotkb:MTH_960(locus name)|uniprotkb:V-ATPase subunit I(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764033 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028987|interpro:IPR014275(ATPase, A1A0, subunit H)|ensemblbacteria:AAB85457(transcript)|ensemblbacteria:MTH_961(gene) interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|ensemblbacteria:AAB85456(transcript)|ensemblbacteria:MTH_960(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain) - - - complex-properties:A 600 kDa subcomplex of the ATP synthase complex was detected. A complex that produces ATP from ADP in the presence of a proton gradient across the membrane.|comment:o27042 is annotated as A0 subcomplex ATP synthase subunit H by authors|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Pdv954v+QJ+c7sR6azQ2Lnbz248187420 rogid:qK/OT7bLgfFw86wMSQ+lRoKPJ14187420 intact-crc:BF7B8F96D345347C|rigid:XQPOqPzFb1e5pdIQRkkfmWfnBzQ false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27743 uniprotkb:O27745 intact:EBI-764042|ensemblbacteria:AAB86180 intact:EBI-764050|ensemblbacteria:AAB86182 psi-mi:acda_metth(display_long)|uniprotkb:cdhA(gene name)|psi-mi:cdhA(display_short)|uniprotkb:ACDS complex carbon monoxide dehydrogenase subunit alpha(gene name synonym)|uniprotkb:MTH_1708(locus name) psi-mi:acdb_metth(display_long)|uniprotkb:ACDS complex acyltransferase(gene name synonym)|uniprotkb:cdhC(gene name)|psi-mi:cdhC(display_short)|uniprotkb:MTH_1710(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764065 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017896|interpro:IPR017900|interpro:IPR004460(CO dehydrogenase/acetyl-CoA synthase complex alpha subunit)|interpro:IPR004137(Prismane)|interpro:IPR011254(Prismane-like)|interpro:IPR016099(Prismane-like, alpha/beta-sandwich)|ensemblbacteria:AAB86180(transcript)|ensemblbacteria:MTH_1708(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0016151"(nickel cation binding)|go:"GO:0018492"("carbon-monoxide dehydrogenase (acceptor) activity")|go:"GO:0043885"("carbon-monoxide dehydrogenase (ferredoxin) activity")|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR004461(CO dehydrogenase/acetyl-CoA synthase complex beta subunit)|interpro:IPR023432|interpro:IPR011254(Prismane-like)|refseq:WP_010877318.1|interpro:IPR038571|ensemblbacteria:AAB86182(transcript)|ensemblbacteria:MTH_1710(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0016151"(nickel cation binding)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018492"("carbon-monoxide dehydrogenase (acceptor) activity")|go:"GO:0043884"(CO-methylating acetyl-CoA synthase activity)|go:"GO:0051536"(iron-sulfur cluster binding) - - - complex-properties:"A 1200 kDa acetyl-CoA decarbonylase/synthase complex was detected. A complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) ."|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:yxi9hm4hHJY4lBtLja/KutJQpTE187420 rogid:7jsc/uh+6UaDKy75cXGrV3XZQhU187420 intact-crc:4AF5BEDF5D21B9D0|rigid:1bdYExjWl2OKkRv0IwU6PXXgyN4 false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27743 uniprotkb:O27748 intact:EBI-764042|ensemblbacteria:AAB86180 intact:EBI-764056|ensemblbacteria:AAB86185 psi-mi:acda_metth(display_long)|uniprotkb:cdhA(gene name)|psi-mi:cdhA(display_short)|uniprotkb:ACDS complex carbon monoxide dehydrogenase subunit alpha(gene name synonym)|uniprotkb:MTH_1708(locus name) psi-mi:acdg_metth(display_long)|uniprotkb:ACDS complex methyltransferase(gene name synonym)|uniprotkb:Corrinoid/iron-sulfur component large subunit(gene name synonym)|uniprotkb:cdhE(gene name)|psi-mi:cdhE(display_short)|uniprotkb:MTH_1713(locus name)|uniprotkb:"5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase"(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764065 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR017896|interpro:IPR017900|interpro:IPR004460(CO dehydrogenase/acetyl-CoA synthase complex alpha subunit)|interpro:IPR004137(Prismane)|interpro:IPR011254(Prismane-like)|interpro:IPR016099(Prismane-like, alpha/beta-sandwich)|ensemblbacteria:AAB86180(transcript)|ensemblbacteria:MTH_1708(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0016151"(nickel cation binding)|go:"GO:0018492"("carbon-monoxide dehydrogenase (acceptor) activity")|go:"GO:0043885"("carbon-monoxide dehydrogenase (ferredoxin) activity")|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) interpro:IPR016041(CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel)|interpro:IPR016218(Acetyl-CoA decarbonylase/synthase complex, gamma subunit)|interpro:IPR023427|interpro:IPR011005(Dihydropteroate synthase-like)|interpro:IPR007202(Putative Fe-S cluster)|refseq:WP_010877321.1|ensemblbacteria:AAB86185(transcript)|ensemblbacteria:MTH_1713(gene)|go:"GO:0005506"(iron ion binding)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding) - - - complex-properties:"A 1200 kDa acetyl-CoA decarbonylase/synthase complex was detected. A complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) ."|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:yxi9hm4hHJY4lBtLja/KutJQpTE187420 rogid:+DfX4KyvX6XiN6a4kcD2nXFF6nk187420 intact-crc:4AF5BEDF5D21B9D0|rigid:1bdYExjWl2OKkRv0IwU6PXXgyN4 false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26884 uniprotkb:O26883 intact:EBI-764090|ensemblbacteria:AAB85293 intact:EBI-764078|ensemblbacteria:AAB85292 psi-mi:y793_metth(display_long)|uniprotkb:MTH_793(locus name) psi-mi:y792_metth(display_long)|uniprotkb:MTH_792(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764098 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020617|interpro:IPR020616|refseq:WP_010876428.1|ensemblbacteria:AAB85293(transcript)|ensemblbacteria:MTH_793(gene)|go:"GO:0016747"(acyltransferase activity, transferring groups other than amino-acyl groups) refseq:WP_048060900.1|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR016039(Thiolase-like)|interpro:IPR013747("3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal")|interpro:IPR004656(Putative condensing enzyme FabH-related)|ensemblbacteria:AAB85292(transcript)|ensemblbacteria:MTH_792(gene)|go:"GO:0016746"(acyltransferase activity) - - - complex-properties:A 300 kDa lipid biosynthesis precursor complex was detected. A complex that converts acetyl-CoA to hydroxy-3-methylglutaryl-CoA , a precursor of lipid biosynthesis.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:89Z6yYou6L7wwuziEN52psF8Wfk187420 rogid:kF/K/mJnmDIrWWvcjj7d7LlsT8M187420 intact-crc:007BF9EA6BA69953|rigid:EbELIvMmIPa5aiGXK/PV6KoWOXo false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26864 uniprotkb:O26837 intact:EBI-764113|ensemblbacteria:AAB85273 intact:EBI-764104|ensemblbacteria:AAB85246 psi-mi:syfb_metth(display_long)|uniprotkb:pheT(gene name)|psi-mi:pheT(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:MTH_770(locus name) psi-mi:syfa_metth(display_long)|uniprotkb:pheS(gene name)|psi-mi:pheS(display_short)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)|uniprotkb:MTH_742(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764122 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR009061(Putative DNA binding)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR022918|interpro:IPR005147(tRNA synthetase, B5)|refseq:WP_010876408.1|interpro:IPR020825|ensemblbacteria:AAB85273(transcript)|ensemblbacteria:MTH_770(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|interpro:IPR041616 interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR022917|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR036388|interpro:IPR036390|ensemblbacteria:AAB85246(transcript)|ensemblbacteria:MTH_742(gene)|go:"GO:0000049"(tRNA binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation) - - - complex-properties:"A 300 kDa Phenylalanyl-tRNA synthetas complex was detected. A complex that catalyses the following reaction ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)."|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:pWWFrN/RZ92bu7WIdOByKzdFG+s187420 rogid:imVuZvMYr0L2RJiLQJWth7mUX58187420 intact-crc:2B5835726B46AE5C|rigid:QInryDBrbifcmnG/nMJapGow5qs false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27217 uniprotkb:Q50519 intact:EBI-764127|ensemblbacteria:AAB85638 intact:EBI-764142 psi-mi:o27217_metth(display_long)|uniprotkb:MTH_1149(locus name) psi-mi:yb50_mettw(display_long)|uniprotkb:ORF2(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:79930(mettw)|taxid:79930("Methanobacterium thermoautotrophicum (strain Winter)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010230(SUF system FeS cluster assembly, SufC ATPase)|refseq:WP_010876773.1|interpro:IPR027417|ensemblbacteria:AAB85638(transcript)|ensemblbacteria:MTH_1149(gene)|go:"GO:0005524"(ATP binding) interpro:IPR000825(SUF system FeS cluster assembly, SufBD)|interpro:IPR037284|go:"GO:0016226"(iron-sulfur cluster assembly) - - - complex-properties:A 200 kDa Fe-S cluster assembly complex was detected. A complex that may be involved in protection of iron sulphur clusters of proteins under oxidative stress.|comment:Proteins O27217 and Q50519 is annotated by authors as homologues of E.coli proteins SufC and SufB respectively which are involved in the bacterial iron uptake system.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:Df8tnLE13tTTTjINlo67Lt8pM1o187420 rogid:Ekdf+Ne8aF9kw7DwNj8upcjTnKg79930 intact-crc:87DB9560485C673F|rigid:hPYX+a8qXBwSJWycJDWrDy/Zr5s false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26782 uniprotkb:O27270 intact:EBI-764158|ensemblbacteria:AAB85191 intact:EBI-764165|ensemblbacteria:AAB85691 psi-mi:psa_metth(display_long)|uniprotkb:20S proteasome alpha subunit(gene name synonym)|uniprotkb:psmA(gene name)|psi-mi:psmA(display_short)|uniprotkb:MTH_686(locus name)|uniprotkb:Proteasome core protein PsmA(gene name synonym) psi-mi:psb_metth(display_long)|uniprotkb:20S proteasome beta subunit(gene name synonym)|uniprotkb:psmB(gene name)|psi-mi:psmB(display_short)|uniprotkb:MTH_1202(locus name)|uniprotkb:Proteasome core protein PsmB(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029055|interpro:IPR019982|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR023332|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:WP_010876325.1|ensemblbacteria:AAB85191(transcript)|ensemblbacteria:MTH_686(gene)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex) interpro:IPR029055|interpro:IPR019983|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023333|refseq:WP_010876826.1|ensemblbacteria:AAB85691(transcript)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|ensemblbacteria:MTH_1202(gene) - - - complex-properties:A 800 kDa proteasome complex was detected. A complex that may be involved in protein degradation.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:YLrfkoBkj+l414fC227/01unNlM187420 rogid:PmaCTDEC/CAAAR5UdsBcE1ivsGI187420 intact-crc:DDF14FD873FB41B9|rigid:UKbFPENhwamgw9mjWoZiiGVjjWc false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26824 uniprotkb:O26640 intact:EBI-764184|ensemblbacteria:AAB85233 intact:EBI-764178|ensemblbacteria:AAB85046 psi-mi:pan_metth(display_long)|uniprotkb:Proteasomal ATPase(gene name synonym)|uniprotkb:pan(gene name)|psi-mi:pan(display_short)|uniprotkb:MTH_728(locus name)|uniprotkb:Proteasome regulatory ATPase(gene name synonym)|uniprotkb:Proteasome regulatory particle(gene name synonym) psi-mi:rad50_metth(display_long)|uniprotkb:rad50(gene name)|psi-mi:rad50(display_short)|uniprotkb:MTH_540(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764210 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR023501|refseq:WP_010876367.1|interpro:IPR027417|interpro:IPR032501|ensemblbacteria:AAB85233(transcript)|ensemblbacteria:MTH_728(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0022623"(proteasome-activating nucleotidase complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043335"(protein unfolding)|interpro:IPR041569 interpro:IPR022982|interpro:IPR013134(Zinc hook, Rad50)|refseq:WP_010876179.1|interpro:IPR027417|interpro:IPR038729|ensemblbacteria:AAB85046(transcript)|ensemblbacteria:MTH_540(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016787"(hydrolase activity) - - - complex-properties:A 800 kDa peoteasome regulatory complex was detected. A complex that may be involved in regulation of protein degradation.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:ZojVTN7LNAK6mUEAWykpcEZotSQ187420 rogid:a/i7ctaVl/i50+yS6iV+HByJ7dY187420 intact-crc:2F3D036200BAD4B1|rigid:nil6fuL9jzjZhA2+EAlztwXXm4I false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26977 uniprotkb:O07165 intact:EBI-764234|ensemblbacteria:AAB85389 intact:EBI-764251|ensemblbacteria:AAB84756 psi-mi:dnag_metth(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:MTH_891(locus name) psi-mi:enda_metth(display_long)|uniprotkb:tRNA-intron endonuclease(gene name synonym)|uniprotkb:endA(gene name)|psi-mi:endA(display_short)|uniprotkb:MTH_250(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764260 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006171(TOPRIM)|interpro:IPR020607|refseq:WP_010876524.1|interpro:IPR034154|ensemblbacteria:AAB85389(transcript)|ensemblbacteria:MTH_891(gene)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003896"(DNA primase activity)|go:"GO:0008143"("poly(A) binding")|go:"GO:0046872"(metal ion binding)|go:"GO:1990077"(primosome complex) interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR006678(tRNA intron endonuclease, N-terminal domain-like)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR016442(tRNA-splicing endonuclease, archaea)|interpro:IPR036167|interpro:IPR036740|ensemblbacteria:AAB84756(transcript)|ensemblbacteria:MTH_250(gene)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0016829"(lyase activity) - - - complex-properties:A 900 kDa exosome complex was detected. A complex that may be involved in the 3'->5' degradation of a variety of RNA species|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:MVmFifDpwr1pp6j8oQnpZg3CKQI187420 rogid:LYFbT7JaQrOTv7GgWcvygHuy+GI187420 intact-crc:D5A7AE516E70A3F9|rigid:mAnZijDFzooE6oGXbyyLu50Uc5I false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26977 uniprotkb:O26779 intact:EBI-764234|ensemblbacteria:AAB85389 intact:EBI-764220|ensemblbacteria:AAB85188 psi-mi:dnag_metth(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:MTH_891(locus name) psi-mi:rrp41_metth(display_long)|uniprotkb:rrp41(gene name)|psi-mi:rrp41(display_short)|uniprotkb:MTH_683(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764260 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006171(TOPRIM)|interpro:IPR020607|refseq:WP_010876524.1|interpro:IPR034154|ensemblbacteria:AAB85389(transcript)|ensemblbacteria:MTH_891(gene)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003896"(DNA primase activity)|go:"GO:0008143"("poly(A) binding")|go:"GO:0046872"(metal ion binding)|go:"GO:1990077"(primosome complex) refseq:WP_010876322.1|dip:DIP-33665N|ensemblbacteria:AAB85188(transcript)|ensemblbacteria:MTH_683(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0006401"(RNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR011807(Exoribonuclease, phosphorolytic domain-containing, archaea)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WNR|go:"GO:0005737"(cytoplasm) - - - complex-properties:A 900 kDa exosome complex was detected. A complex that may be involved in the 3'->5' degradation of a variety of RNA species|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:MVmFifDpwr1pp6j8oQnpZg3CKQI187420 rogid:572vjxkxfVoe8tdIS5xhFe/HvYc187420 intact-crc:D5A7AE516E70A3F9|rigid:mAnZijDFzooE6oGXbyyLu50Uc5I false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26977 uniprotkb:O26778 intact:EBI-764234|ensemblbacteria:AAB85389 intact:EBI-764215|ensemblbacteria:AAB85187 psi-mi:dnag_metth(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:MTH_891(locus name) psi-mi:rrp42_metth(display_long)|uniprotkb:rrp42(gene name)|psi-mi:rrp42(display_short)|uniprotkb:MTH_682(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764260 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006171(TOPRIM)|interpro:IPR020607|refseq:WP_010876524.1|interpro:IPR034154|ensemblbacteria:AAB85389(transcript)|ensemblbacteria:MTH_891(gene)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003896"(DNA primase activity)|go:"GO:0008143"("poly(A) binding")|go:"GO:0046872"(metal ion binding)|go:"GO:1990077"(primosome complex) refseq:WP_010876321.1|dip:DIP-33664N|ensemblbacteria:AAB85187(transcript)|ensemblbacteria:MTH_682(gene)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005737"(cytoplasm)|go:"GO:0006401"(RNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR020869|interpro:IPR027408|interpro:IPR036345|rcsb pdb:2WNR - - - complex-properties:A 900 kDa exosome complex was detected. A complex that may be involved in the 3'->5' degradation of a variety of RNA species|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:MVmFifDpwr1pp6j8oQnpZg3CKQI187420 rogid:Lno57rcKBgwaDlH6LkTwkzlkVxQ187420 intact-crc:D5A7AE516E70A3F9|rigid:mAnZijDFzooE6oGXbyyLu50Uc5I false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O26977 uniprotkb:O26780 intact:EBI-764234|ensemblbacteria:AAB85389 intact:EBI-764226|ensemblbacteria:AAB85189 psi-mi:dnag_metth(display_long)|uniprotkb:dnaG(gene name)|psi-mi:dnaG(display_short)|uniprotkb:MTH_891(locus name) psi-mi:rrp4_metth(display_long)|uniprotkb:rrp4(gene name)|psi-mi:rrp4(display_short)|uniprotkb:MTH_684(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764260 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006171(TOPRIM)|interpro:IPR020607|refseq:WP_010876524.1|interpro:IPR034154|ensemblbacteria:AAB85389(transcript)|ensemblbacteria:MTH_891(gene)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003896"(DNA primase activity)|go:"GO:0008143"("poly(A) binding")|go:"GO:0046872"(metal ion binding)|go:"GO:1990077"(primosome complex) interpro:IPR026699|interpro:IPR023474|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR003029(S1, RNA binding)|interpro:IPR022967|refseq:WP_010876323.1|interpro:IPR025721|interpro:IPR036612|ensemblbacteria:AAB85189(transcript)|ensemblbacteria:MTH_684(gene)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005737"(cytoplasm)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0008143"("poly(A) binding") - - - complex-properties:A 900 kDa exosome complex was detected. A complex that may be involved in the 3'->5' degradation of a variety of RNA species|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:MVmFifDpwr1pp6j8oQnpZg3CKQI187420 rogid:SRSn/SO6o93SEtcq/6gMXoPxBOo187420 intact-crc:D5A7AE516E70A3F9|rigid:mAnZijDFzooE6oGXbyyLu50Uc5I false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27229 uniprotkb:O27230 intact:EBI-763831|ensemblbacteria:AAB85650 intact:EBI-763837|ensemblbacteria:AAB85651 psi-mi:mtrc_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C(gene name synonym)|uniprotkb:mtrC(gene name)|psi-mi:mtrC(display_short)|uniprotkb:MTH_1161(locus name) psi-mi:mtrd_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit D(gene name synonym)|uniprotkb:mtrD(gene name)|psi-mi:mtrD(display_short)|uniprotkb:MTH_1162(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010876785.1|interpro:IPR005865(Tetrahydromethanopterin S-methyltransferase, subunit C)|ensemblbacteria:AAB85650(transcript)|ensemblbacteria:MTH_1161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) interpro:IPR005779(Tetrahydromethanopterin S-methyltransferase, subunit D)|ensemblbacteria:AAB85651(transcript)|ensemblbacteria:MTH_1162(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:WP_010876786.1 - - - complex-properties:A putative supercomplex containing subunits of the methyltransferase complex and subunits of the ATP synthase complex was detected.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:GatuOqnzmKd2UdPN37LP+Ur+7yA187420 rogid:ttWtB3iR+6n6UOcHlkuYd2Z1v2I187420 intact-crc:CD9AF3F32F9A1C2C|rigid:LbRM3j9cD/uvFNp8vnzS3QOBD2M false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27229 uniprotkb:O27231 intact:EBI-763831|ensemblbacteria:AAB85650 intact:EBI-763843|uniprotkb:Q59582|ensemblbacteria:AAB85652 psi-mi:mtrc_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C(gene name synonym)|uniprotkb:mtrC(gene name)|psi-mi:mtrC(display_short)|uniprotkb:MTH_1161(locus name) psi-mi:mtre_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E(gene name synonym)|uniprotkb:mtrE(gene name)|psi-mi:mtrE(display_short)|uniprotkb:MTH_1163(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010876785.1|interpro:IPR005865(Tetrahydromethanopterin S-methyltransferase, subunit C)|ensemblbacteria:AAB85650(transcript)|ensemblbacteria:MTH_1161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) interpro:IPR005780(Tetrahydromethanopterin S-methyltransferase, subunit E)|ensemblbacteria:AAB85652(transcript)|ensemblbacteria:MTH_1163(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006814"(sodium ion transport)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation)|refseq:WP_010876787.1 - - - complex-properties:A putative supercomplex containing subunits of the methyltransferase complex and subunits of the ATP synthase complex was detected.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:GatuOqnzmKd2UdPN37LP+Ur+7yA187420 rogid:C/eTJ1Jzn+svHNqD/FIMkQDxtzQ187420 intact-crc:CD9AF3F32F9A1C2C|rigid:LbRM3j9cD/uvFNp8vnzS3QOBD2M false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27229 uniprotkb:O27225 intact:EBI-763831|ensemblbacteria:AAB85650 intact:EBI-763813|ensemblbacteria:AAB85646 psi-mi:mtrc_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C(gene name synonym)|uniprotkb:mtrC(gene name)|psi-mi:mtrC(display_short)|uniprotkb:MTH_1161(locus name) psi-mi:mtrg_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit G(gene name synonym)|uniprotkb:mtrG(gene name)|psi-mi:mtrG(display_short)|uniprotkb:MTH_1157(locus name) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010876785.1|interpro:IPR005865(Tetrahydromethanopterin S-methyltransferase, subunit C)|ensemblbacteria:AAB85650(transcript)|ensemblbacteria:MTH_1161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) refseq:WP_010876781.1|interpro:IPR005866(Tetrahydromethanopterin S-methyltransferase, subunit G)|ensemblbacteria:AAB85646(transcript)|ensemblbacteria:MTH_1157(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) - - - complex-properties:A putative supercomplex containing subunits of the methyltransferase complex and subunits of the ATP synthase complex was detected.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:GatuOqnzmKd2UdPN37LP+Ur+7yA187420 rogid:+OLyl8KLmEqaZ3FZrAuc2pP4xu4187420 intact-crc:CD9AF3F32F9A1C2C|rigid:LbRM3j9cD/uvFNp8vnzS3QOBD2M false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27229 uniprotkb:O27038 intact:EBI-763831|ensemblbacteria:AAB85650 intact:EBI-764009|ensemblbacteria:AAB85453 psi-mi:mtrc_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C(gene name synonym)|uniprotkb:mtrC(gene name)|psi-mi:mtrC(display_short)|uniprotkb:MTH_1161(locus name) psi-mi:vatc_metth(display_long)|uniprotkb:atpC(gene name)|psi-mi:atpC(display_short)|uniprotkb:MTH_957(locus name)|uniprotkb:V-ATPase subunit C(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010876785.1|interpro:IPR005865(Tetrahydromethanopterin S-methyltransferase, subunit C)|ensemblbacteria:AAB85650(transcript)|ensemblbacteria:MTH_1161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) interpro:IPR014272(ATPase, A1 complex, subunit C archaea)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|refseq:WP_010876588.1|interpro:IPR035067|interpro:IPR036079|ensemblbacteria:AAB85453(transcript)|ensemblbacteria:MTH_957(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0042777"(plasma membrane ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR044911 - - - complex-properties:A putative supercomplex containing subunits of the methyltransferase complex and subunits of the ATP synthase complex was detected.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:GatuOqnzmKd2UdPN37LP+Ur+7yA187420 rogid:zCM9qB52SphcE58BMmSlIZ3k8/M187420 intact-crc:CD9AF3F32F9A1C2C|rigid:LbRM3j9cD/uvFNp8vnzS3QOBD2M false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:O27229 uniprotkb:O27041 intact:EBI-763831|ensemblbacteria:AAB85650 intact:EBI-764021|ensemblbacteria:AAB85456 psi-mi:mtrc_metth(display_long)|uniprotkb:N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C(gene name synonym)|uniprotkb:mtrC(gene name)|psi-mi:mtrC(display_short)|uniprotkb:MTH_1161(locus name) psi-mi:vati_metth(display_long)|uniprotkb:atpI(gene name)|psi-mi:atpI(display_short)|uniprotkb:MTH_960(locus name)|uniprotkb:V-ATPase subunit I(gene name synonym) psi-mi:"MI:0276"(blue native page) Farhoud et al. (2005) pubmed:16037073 taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-764274 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_010876785.1|interpro:IPR005865(Tetrahydromethanopterin S-methyltransferase, subunit C)|ensemblbacteria:AAB85650(transcript)|ensemblbacteria:MTH_1161(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019386"(methanogenesis, from carbon dioxide)|go:"GO:0030269"(tetrahydromethanopterin S-methyltransferase activity)|go:"GO:0032259"(methylation) interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|ensemblbacteria:AAB85456(transcript)|ensemblbacteria:MTH_960(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain) - - - complex-properties:A putative supercomplex containing subunits of the methyltransferase complex and subunits of the ATP synthase complex was detected.|dataset:Archaea - Interaction dataset based on Archaea proteins taxid:187420(metth)|taxid:187420(Methanobacterium thermoautotrophicum) - 2005/12/05 2014/10/16 rogid:GatuOqnzmKd2UdPN37LP+Ur+7yA187420 rogid:qK/OT7bLgfFw86wMSQ+lRoKPJ14187420 intact-crc:CD9AF3F32F9A1C2C|rigid:LbRM3j9cD/uvFNp8vnzS3QOBD2M false - - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)