#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O08992 uniprotkb:P30203 intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912 intact:EBI-2873748|ensembl:ENSP00000323280|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5 psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short) psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym) psi-mi:"MI:0398"(two hybrid pooling approach) Gimferrer et al. (2005) pubmed:16034076|mint:MINT-5217837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7696978|mint:MINT-62372 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1351670(identity) ensembl:ENSG00000013725(gene)|ensembl:ENST00000313421(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|rcsb pdb:5A2E|refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718801.1|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|mint:MINT-1351661(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/08/29 2014/10/16 rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090 rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606 intact-crc:9D69655CC42D9F0C|rigid:6A8/0GC0jDRqaVDlNfHSIvPboqo false tag:?-?(MINT-1351671) binding-associated region:613-668(MINT-1351662)|tag:?-?(MINT-1351665) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O08992 uniprotkb:P30203 intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912 intact:EBI-2873748|ensembl:ENSP00000323280|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5 psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short) psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym) psi-mi:"MI:0096"(pull down) Gimferrer et al. (2005) pubmed:16034076|mint:MINT-5217837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7697023|mint:MINT-62374 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1351688(identity) ensembl:ENSG00000013725(gene)|ensembl:ENST00000313421(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|rcsb pdb:5A2E|refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718801.1|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|mint:MINT-1351682(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/29 2014/10/16 rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090 rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606 intact-crc:465C06182F9E62E5|rigid:6A8/0GC0jDRqaVDlNfHSIvPboqo false tag:?-?(MINT-1351692)|binding-associated region:109-298(MINT-1351689) tag:?-?(MINT-1351683) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:O08992 uniprotkb:P30203 intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912 intact:EBI-2873748|ensembl:ENSP00000323280|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5 psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short) psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gimferrer et al. (2005) pubmed:16034076|mint:MINT-5217837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7697051|mint:MINT-62375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1351710(identity) ensembl:ENSG00000013725(gene)|ensembl:ENST00000313421(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|rcsb pdb:5A2E|refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718801.1|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|mint:MINT-1351702(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B F4C|comment:homomint|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2005/08/29 2014/10/16 rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090 rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606 intact-crc:4EDAE74C9D819E04|rigid:6A8/0GC0jDRqaVDlNfHSIvPboqo false tag:?-?(MINT-1351714)|binding-associated region:109-298(MINT-1351711) tag:?-?(MINT-1351705)|mutation decreasing interaction:665-668(MINT-1351703) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P30203 uniprotkb:O00560 intact:EBI-2873748|ensembl:ENSP00000323280|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5 intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7 psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym) psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym) psi-mi:"MI:0428"(imaging technique) Gimferrer et al. (2005) pubmed:16034076|mint:MINT-5217837 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7697083|mint:MINT-62377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000013725(gene)|ensembl:ENST00000313421(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|rcsb pdb:5A2E|refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718801.1|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|mint:MINT-1351753(identity) ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N|mint:MINT-1351758(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5A F5B|comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/08/29 2014/10/16 rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606 rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606 intact-crc:B90603C8E92956F8|rigid:hbobZgcnxyzWRhh+AAnV0MKljwM false - - - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O08992 uniprotkb:P30203 intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912 intact:EBI-2873748|ensembl:ENSP00000323280|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5 psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short) psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym) psi-mi:"MI:0397"(two hybrid array) Gimferrer et al. (2005) pubmed:16034076|mint:MINT-5217837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7697145|mint:MINT-62373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664|mint:MINT-1351783(identity) ensembl:ENSG00000013725(gene)|ensembl:ENST00000313421(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|rcsb pdb:5A2E|refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718801.1|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|mint:MINT-1351768(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2 F3|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/08/29 2014/10/16 rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090 rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606 intact-crc:38AA440E308F49EA|rigid:6A8/0GC0jDRqaVDlNfHSIvPboqo false tag:?-?(MINT-1351787)|binding-associated region:109-298(MINT-1351784) mutation decreasing interaction:665-665,666-666,667-667,668-668,662-662(MINT-1351772)|tag:?-?(MINT-1351778)|binding-associated region:613-668(MINT-1351769) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P30203 uniprotkb:O00560 intact:EBI-2873748|ensembl:ENSP00000323280|uniprotkb:Q9UMF2|uniprotkb:Q9Y4K8|uniprotkb:Q9Y4L0|uniprotkb:Q9Y4K7|uniprotkb:Q9Y4K9|uniprotkb:A4KAD4|uniprotkb:A4KAD5 intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7 psi-mi:cd6_human(display_long)|uniprotkb:CD6(gene name)|psi-mi:CD6(display_short)|uniprotkb:T12(gene name synonym)|uniprotkb:TP120(gene name synonym) psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gimferrer et al. (2005) pubmed:16034076|mint:MINT-5217837 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7697189|mint:MINT-62376 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000013725(gene)|ensembl:ENST00000313421(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|rcsb pdb:5A2E|refseq:XP_011543664.1|refseq:NP_006716.3|refseq:XP_006718801.1|refseq:XP_006718804.1|refseq:NP_001241679.1|refseq:NP_001241680.1|dip:DIP-43704N|mint:MINT-1351797(identity) ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N|mint:MINT-1351801(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4D|comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/08/29 2014/10/16 rogid:7GTuuSJHssuyL3S2CiBAN14eP9c9606 rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606 intact-crc:080ED51CA6A7771B|rigid:hbobZgcnxyzWRhh+AAnV0MKljwM false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)