#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P22812 uniprotkb:Q05652 intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0114"(x-ray crystallography) Moncrieffe et al. (2005) pubmed:16004997|imex:IM-11179|mint:MINT-5217824 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7692584|mint:MINT-62389|imex:IM-11179-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N|mint:MINT-1351578(identity) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N|mint:MINT-1351586(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/30 2014/10/16 rogid:v00LZV72cvvYVI5cCthONXIlmrs7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:C01664D4C875CAB4|rigid:CBP6+LAxAvEVwY1/uwqyn2iFqUM false binding-associated region:1-183(MINT-1351579) binding-associated region:26-131(MINT-1351587) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P22812 uniprotkb:Q05652 intact:EBI-93181|uniprotkb:Q9VN15|uniprotkb:B7Z0I9|uniprotkb:E8NH30|ensemblmetazoa:FBpp0291542 intact:EBI-115059|uniprotkb:Q9VB57|ensemblmetazoa:FBpp0084549|ensemblmetazoa:FBpp0306780|uniprotkb:B8A3X2|uniprotkb:Q8T005 psi-mi:tube_drome(display_long)|uniprotkb:CG10520(orf name)|uniprotkb:tub(gene name)|psi-mi:tub(display_short)|uniprotkb:tube(gene name synonym) psi-mi:kpel_drome(display_long)|uniprotkb:CG5974(orf name)|uniprotkb:pll(gene name)|psi-mi:pll(display_short) psi-mi:"MI:0027"(cosedimentation) Moncrieffe et al. (2005) pubmed:16004997|imex:IM-11179|mint:MINT-5217824 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7692616|mint:MINT-62390|imex:IM-11179-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001189164.1|flybase:FBgn0003882|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000488(Death)|interpro:IPR011029(DEATH-like)|interpro:IPR029397|rcsb pdb:1D2Z|reactome:R-DME-209442|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214863|reactome:R-DME-214869|reactome:R-DME-214874|go:"GO:0045087"(innate immune response)|ensemblmetazoa:FBgn0003882(gene)|ensemblmetazoa:FBtr0302338(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009620"(response to fungus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|dip:DIP-27623N|mint:MINT-1351599(identity) refseq:NP_476971.1|flybase:FBgn0010441|ensemblmetazoa:FBgn0010441(gene)|ensemblmetazoa:FBtr0085179(transcript)|ensemblmetazoa:FBtr0334732(transcript)|go:"GO:0002804"(positive regulation of antifungal peptide production)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007352"(zygotic specification of dorsal/ventral axis)|go:"GO:0005886"(plasma membrane)|go:"GO:0007526"(larval somatic muscle development)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035172"(hemocyte proliferation)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048262"(determination of dorsal/ventral asymmetry)|go:"GO:0061760"(antifungal innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037924|rcsb pdb:1D2Z|rcsb pdb:1IK7|rcsb pdb:1YGO|reactome:R-DME-214842|reactome:R-DME-214844|reactome:R-DME-214862|reactome:R-DME-214869|reactome:R-DME-214874|refseq:NP_001263008.1|dip:DIP-27622N|mint:MINT-1351607(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/30 2014/10/16 rogid:v00LZV72cvvYVI5cCthONXIlmrs7227 rogid:mzeAsv/CpnfUVe9V4AISjg51tqA7227 intact-crc:47FFEF1B83D301F8|rigid:CBP6+LAxAvEVwY1/uwqyn2iFqUM false binding-associated region:1-183(MINT-1351600) binding-associated region:26-131(MINT-1351608) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)