#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08575 uniprotkb:P08575 intact:EBI-1341|uniprotkb:A8K7W6|uniprotkb:Q16614|uniprotkb:Q9H0Y6|uniprotkb:A0A0A0MT22|uniprotkb:X6R433|ensembl:ENSP00000411355|ensembl:ENSP00000458322|ensembl:ENSP00000461074 intact:EBI-1341|uniprotkb:A8K7W6|uniprotkb:Q16614|uniprotkb:Q9H0Y6|uniprotkb:A0A0A0MT22|uniprotkb:X6R433|ensembl:ENSP00000411355|ensembl:ENSP00000458322|ensembl:ENSP00000461074 psi-mi:ptprc_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)|uniprotkb:CD45(gene name synonym)|uniprotkb:T200(gene name synonym)|uniprotkb:Leukocyte common antigen(gene name synonym) psi-mi:ptprc_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)|uniprotkb:CD45(gene name synonym)|uniprotkb:T200(gene name synonym)|uniprotkb:Leukocyte common antigen(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7669278|mint:MINT-62302|imex:IM-10850-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002829.3|refseq:NP_563578.2|dip:DIP-224N|refseq:XP_006711535.1|refseq:XP_006711536.1|refseq:XP_006711537.1|ensembl:ENSG00000081237(gene)|ensembl:ENSG00000262418(gene)|ensembl:ENST00000442510(transcript)|ensembl:ENST00000573477(transcript)|ensembl:ENST00000573679(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032059"(bleb)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0044855"(plasma membrane raft distribution)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048539"(bone marrow development)|go:"GO:0048864"(stem cell development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050857"(positive regulation of antigen receptor-mediated signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098857"(membrane microdomain)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1904155"(DN2 thymocyte differentiation)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000473"(positive regulation of hematopoietic stem cell migration)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR036116|mint:P08575|rcsb pdb:1YGR|rcsb pdb:1YGU|rcsb pdb:5FMV|rcsb pdb:5FN6|rcsb pdb:5FN7|reactome:R-HSA-202427|reactome:R-HSA-416700|reactome:R-HSA-6798695|mint:MINT-1349866(identity) refseq:NP_002829.3|refseq:NP_563578.2|dip:DIP-224N|refseq:XP_006711535.1|refseq:XP_006711536.1|refseq:XP_006711537.1|ensembl:ENSG00000081237(gene)|ensembl:ENSG00000262418(gene)|ensembl:ENST00000442510(transcript)|ensembl:ENST00000573477(transcript)|ensembl:ENST00000573679(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032059"(bleb)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0044855"(plasma membrane raft distribution)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048539"(bone marrow development)|go:"GO:0048864"(stem cell development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050857"(positive regulation of antigen receptor-mediated signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098857"(membrane microdomain)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1904155"(DN2 thymocyte differentiation)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000473"(positive regulation of hematopoietic stem cell migration)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR036116|mint:P08575|rcsb pdb:1YGR|rcsb pdb:1YGU|rcsb pdb:5FMV|rcsb pdb:5FN6|rcsb pdb:5FN7|reactome:R-HSA-202427|reactome:R-HSA-416700|reactome:R-HSA-6798695|mint:MINT-1349856(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/23 2018/04/06 rogid:rrMiH60EcAzRWaaapYTjNU5+1IY9606 rogid:rrMiH60EcAzRWaaapYTjNU5+1IY9606 intact-crc:3D19F9A150F1E175|rigid:/aCe9f+TS2SV6uFYvuaLkOU7+7U false tag:?-?(MINT-1349870)|binding-associated region:579-599(MINT-1349867) binding-associated region:579-599(MINT-1349857)|tag:?-?(MINT-1349860) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92729 uniprotkb:Q92729 intact:EBI-7052301|ensembl:ENSP00000334941|uniprotkb:Q59HA4|intact:MINT-1349420|uniprotkb:Q5SYU5|uniprotkb:O00197|uniprotkb:A6H8L1|uniprotkb:P78399|uniprotkb:Q92735|uniprotkb:Q5SYU4|uniprotkb:Q92850 intact:EBI-7052301|ensembl:ENSP00000334941|uniprotkb:Q59HA4|intact:MINT-1349420|uniprotkb:Q5SYU5|uniprotkb:O00197|uniprotkb:A6H8L1|uniprotkb:P78399|uniprotkb:Q92735|uniprotkb:Q5SYU4|uniprotkb:Q92850 psi-mi:ptpru_human(display_long)|uniprotkb:PTPRU(gene name)|psi-mi:PTPRU(display_short)|uniprotkb:PCP2(gene name synonym)|uniprotkb:FMI(gene name synonym)|uniprotkb:PTPRO(gene name synonym)|uniprotkb:Receptor-type protein-tyrosine phosphatase psi(gene name synonym)|uniprotkb:Pancreatic carcinoma phosphatase 2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor omicron(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase J(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pi(gene name synonym) psi-mi:ptpru_human(display_long)|uniprotkb:PTPRU(gene name)|psi-mi:PTPRU(display_short)|uniprotkb:PCP2(gene name synonym)|uniprotkb:FMI(gene name synonym)|uniprotkb:PTPRO(gene name synonym)|uniprotkb:Receptor-type protein-tyrosine phosphatase psi(gene name synonym)|uniprotkb:Pancreatic carcinoma phosphatase 2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor omicron(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase J(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pi(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7669307|mint:MINT-62303|imex:IM-10850-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000060656(gene)|ensembl:ENST00000345512(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:Q92729|rcsb pdb:6SUB|rcsb pdb:6SUC|reactome:R-HSA-1433557|refseq:NP_001181930.1|refseq:NP_005695.3|refseq:NP_573439.2|refseq:NP_573438.3|mint:MINT-1349450(identity) ensembl:ENSG00000060656(gene)|ensembl:ENST00000345512(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:Q92729|rcsb pdb:6SUB|rcsb pdb:6SUC|reactome:R-HSA-1433557|refseq:NP_001181930.1|refseq:NP_005695.3|refseq:NP_573439.2|refseq:NP_573438.3|mint:MINT-1349440(identity) - comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin|comment:"Stoichiometry: 1.0" comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin|comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/23 2016/10/21 rogid:zEYsgwn37ANdzpiq5f8h2TL+XD89606 rogid:zEYsgwn37ANdzpiq5f8h2TL+XD89606 intact-crc:91E4A6C9FEA02C7A|rigid:pRBYfoCph+d9nxOcv/sigasQiis false tag:?-?(MINT-1349454)|binding-associated region:747-770(MINT-1349451) tag:?-?(MINT-1349444)|binding-associated region:747-770(MINT-1349441) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18433 uniprotkb:P18433 intact:EBI-2609645|uniprotkb:D3DVX5|uniprotkb:Q14513|uniprotkb:Q7Z2I2|uniprotkb:A8K2G8|uniprotkb:Q96TD9|ensembl:ENSP00000382787|intact:EBI-11028029 intact:EBI-2609645|uniprotkb:D3DVX5|uniprotkb:Q14513|uniprotkb:Q7Z2I2|uniprotkb:A8K2G8|uniprotkb:Q96TD9|ensembl:ENSP00000382787|intact:EBI-11028029 psi-mi:ptpra_human(display_long)|uniprotkb:PTPRA(gene name)|psi-mi:PTPRA(display_short)|uniprotkb:PTPA(gene name synonym)|uniprotkb:PTPRL2(gene name synonym) psi-mi:ptpra_human(display_long)|uniprotkb:PTPRA(gene name)|psi-mi:PTPRA(display_short)|uniprotkb:PTPA(gene name synonym)|uniprotkb:PTPRL2(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7669353|mint:MINT-62304|imex:IM-10850-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132670(gene)|ensembl:ENST00000399903(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|mint:P18433|rcsb pdb:6UZT|reactome:R-HSA-375165|reactome:R-HSA-5673001|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|refseq:NP_002827.1|refseq:NP_543030.1|refseq:NP_543031.1|mint:MINT-1349678(identity) ensembl:ENSG00000132670(gene)|ensembl:ENST00000399903(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|mint:P18433|rcsb pdb:6UZT|reactome:R-HSA-375165|reactome:R-HSA-5673001|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|refseq:NP_002827.1|refseq:NP_543030.1|refseq:NP_543031.1|mint:MINT-1349668(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/23 2018/04/06 rogid:dWjvj2zG0Kapb8MhDjinV+LpG109606 rogid:dWjvj2zG0Kapb8MhDjinV+LpG109606 intact-crc:7F756DE0B9F5E010|rigid:1h3EmYZNwAQ4GRlYhNCtUeESksI false binding-associated region:152-175(MINT-1349679)|tag:?-?(MINT-1349682) binding-associated region:152-175(MINT-1349669)|tag:?-?(MINT-1349672) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23470 uniprotkb:P23470 intact:EBI-2258115|uniprotkb:Q15623|uniprotkb:Q59EE0|uniprotkb:Q68DU5|uniprotkb:B2RU12|uniprotkb:B7ZLX5|ensembl:ENSP00000418112 intact:EBI-2258115|uniprotkb:Q15623|uniprotkb:Q59EE0|uniprotkb:Q68DU5|uniprotkb:B2RU12|uniprotkb:B7ZLX5|ensembl:ENSP00000418112 psi-mi:ptprg_human(display_long)|uniprotkb:PTPRG(gene name)|psi-mi:PTPRG(display_short)|uniprotkb:PTPG(gene name synonym) psi-mi:ptprg_human(display_long)|uniprotkb:PTPRG(gene name)|psi-mi:PTPRG(display_short)|uniprotkb:PTPG(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7669419|mint:MINT-62305|imex:IM-10850-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002832.3|refseq:XP_005265410.1|ensembl:ENSG00000144724(gene)|ensembl:ENST00000474889(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:2H4V|rcsb pdb:2HY3|rcsb pdb:2NLK|rcsb pdb:2PBN|rcsb pdb:3JXH|rcsb pdb:3QCB|rcsb pdb:3QCC|rcsb pdb:3QCD|rcsb pdb:3QCE|rcsb pdb:3QCF|rcsb pdb:3QCG|rcsb pdb:3QCH|rcsb pdb:3QCI|rcsb pdb:3QCJ|rcsb pdb:3QCK|rcsb pdb:3QCL|rcsb pdb:3QCM|rcsb pdb:3QCN|rcsb pdb:5E5R|go:"GO:0007420"(brain development)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:MINT-1349925(identity) refseq:NP_002832.3|refseq:XP_005265410.1|ensembl:ENSG00000144724(gene)|ensembl:ENST00000474889(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:2H4V|rcsb pdb:2HY3|rcsb pdb:2NLK|rcsb pdb:2PBN|rcsb pdb:3JXH|rcsb pdb:3QCB|rcsb pdb:3QCC|rcsb pdb:3QCD|rcsb pdb:3QCE|rcsb pdb:3QCF|rcsb pdb:3QCG|rcsb pdb:3QCH|rcsb pdb:3QCI|rcsb pdb:3QCJ|rcsb pdb:3QCK|rcsb pdb:3QCL|rcsb pdb:3QCM|rcsb pdb:3QCN|rcsb pdb:5E5R|go:"GO:0007420"(brain development)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:MINT-1349935(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/23 2016/10/21 rogid:9184ikfJS88Ndx9dhhblgdCFI+Y9606 rogid:9184ikfJS88Ndx9dhhblgdCFI+Y9606 intact-crc:787B01500446FD30|rigid:pnpQvRV8KPdRwsp7IhBs9VFoieY false binding-associated region:738-760(MINT-1349926)|tag:?-?(MINT-1349929) tag:?-?(MINT-1349939)|binding-associated region:738-760(MINT-1349936) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12913 uniprotkb:Q12913 intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010 intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010 psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym) psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7669448|mint:MINT-62306|imex:IM-10850-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369|mint:MINT-1349325(identity) refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369|mint:MINT-1349335(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/23 2016/10/21 rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606 rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606 intact-crc:17323C9D0F0A40D9|rigid:pxih3Ueb1I7Vu7JGcT8TivM+jL8 false tag:?-?(MINT-1349329)|binding-associated region:972-996(MINT-1349326) tag:?-?(MINT-1349339)|binding-associated region:972-996(MINT-1349336) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16827 uniprotkb:Q16827 intact:EBI-723739|uniprotkb:A0AV39|uniprotkb:Q13101|ensembl:ENSP00000281171|ensembl:ENSP00000501352|ensembl:ENSP00000501538|uniprotkb:Q9UBF0|uniprotkb:Q9UBT5|uniprotkb:Q8IYG3 intact:EBI-723739|uniprotkb:A0AV39|uniprotkb:Q13101|ensembl:ENSP00000281171|ensembl:ENSP00000501352|ensembl:ENSP00000501538|uniprotkb:Q9UBF0|uniprotkb:Q9UBT5|uniprotkb:Q8IYG3 psi-mi:ptpro_human(display_long)|uniprotkb:Glomerular epithelial protein 1(gene name synonym)|uniprotkb:Protein tyrosine phosphatase U2(gene name synonym)|uniprotkb:PTPRO(gene name)|psi-mi:PTPRO(display_short)|uniprotkb:GLEPP1(gene name synonym)|uniprotkb:PTPU2(gene name synonym) psi-mi:ptpro_human(display_long)|uniprotkb:Glomerular epithelial protein 1(gene name synonym)|uniprotkb:Protein tyrosine phosphatase U2(gene name synonym)|uniprotkb:PTPRO(gene name)|psi-mi:PTPRO(display_short)|uniprotkb:GLEPP1(gene name synonym)|uniprotkb:PTPU2(gene name synonym) psi-mi:"MI:0808"(comigration in sds page) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7669477|mint:MINT-62307|imex:IM-10850-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002839.1|refseq:NP_109592.1|ensembl:ENST00000674316(transcript)|ensembl:ENST00000674261(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003093"(regulation of glomerular filtration)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032835"(glomerulus development)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036060"(slit diaphragm assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR042996|rcsb pdb:2G59|rcsb pdb:2GJT|reactome:R-HSA-9034015|go:"GO:0030424"(axon)|ensembl:ENSG00000151490(gene)|ensembl:ENST00000281171(transcript)|refseq:NP_109593.1|refseq:NP_109594.1|refseq:NP_109595.1|refseq:NP_109596.1|mint:MINT-1350393(identity) refseq:NP_002839.1|refseq:NP_109592.1|ensembl:ENST00000674316(transcript)|ensembl:ENST00000674261(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003093"(regulation of glomerular filtration)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032835"(glomerulus development)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036060"(slit diaphragm assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR042996|rcsb pdb:2G59|rcsb pdb:2GJT|reactome:R-HSA-9034015|go:"GO:0030424"(axon)|ensembl:ENSG00000151490(gene)|ensembl:ENST00000281171(transcript)|refseq:NP_109593.1|refseq:NP_109594.1|refseq:NP_109595.1|refseq:NP_109596.1|mint:MINT-1350403(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/08/23 2016/10/21 rogid:On01UwkglziGIJIEHE8TrOkOHd89606 rogid:On01UwkglziGIJIEHE8TrOkOHd89606 intact-crc:A57C6FC229977B67|rigid:rowHzEqOIc9LgTCKVHgZG6uVxK8 false tag:?-?(MINT-1350397)|binding-associated region:820-844(MINT-1350394) tag:?-?(MINT-1350407)|binding-associated region:820-844(MINT-1350404) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P08575 uniprotkb:P08575 intact:EBI-1341|uniprotkb:A8K7W6|uniprotkb:Q16614|uniprotkb:Q9H0Y6|uniprotkb:A0A0A0MT22|uniprotkb:X6R433|ensembl:ENSP00000411355|ensembl:ENSP00000458322|ensembl:ENSP00000461074 intact:EBI-1341|uniprotkb:A8K7W6|uniprotkb:Q16614|uniprotkb:Q9H0Y6|uniprotkb:A0A0A0MT22|uniprotkb:X6R433|ensembl:ENSP00000411355|ensembl:ENSP00000458322|ensembl:ENSP00000461074 psi-mi:ptprc_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)|uniprotkb:CD45(gene name synonym)|uniprotkb:T200(gene name synonym)|uniprotkb:Leukocyte common antigen(gene name synonym) psi-mi:ptprc_human(display_long)|uniprotkb:PTPRC(gene name)|psi-mi:PTPRC(display_short)|uniprotkb:CD45(gene name synonym)|uniprotkb:T200(gene name synonym)|uniprotkb:Leukocyte common antigen(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669535|mint:MINT-62283|imex:IM-10850-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002829.3|refseq:NP_563578.2|dip:DIP-224N|refseq:XP_006711535.1|refseq:XP_006711536.1|refseq:XP_006711537.1|ensembl:ENSG00000081237(gene)|ensembl:ENSG00000262418(gene)|ensembl:ENST00000442510(transcript)|ensembl:ENST00000573477(transcript)|ensembl:ENST00000573679(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032059"(bleb)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0044855"(plasma membrane raft distribution)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048539"(bone marrow development)|go:"GO:0048864"(stem cell development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050857"(positive regulation of antigen receptor-mediated signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098857"(membrane microdomain)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1904155"(DN2 thymocyte differentiation)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000473"(positive regulation of hematopoietic stem cell migration)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR036116|mint:P08575|rcsb pdb:1YGR|rcsb pdb:1YGU|rcsb pdb:5FMV|rcsb pdb:5FN6|rcsb pdb:5FN7|reactome:R-HSA-202427|reactome:R-HSA-416700|reactome:R-HSA-6798695|mint:MINT-1349959(identity) refseq:NP_002829.3|refseq:NP_563578.2|dip:DIP-224N|refseq:XP_006711535.1|refseq:XP_006711536.1|refseq:XP_006711537.1|ensembl:ENSG00000081237(gene)|ensembl:ENSG00000262418(gene)|ensembl:ENST00000442510(transcript)|ensembl:ENST00000573477(transcript)|ensembl:ENST00000573679(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032059"(bleb)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0044855"(plasma membrane raft distribution)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0048539"(bone marrow development)|go:"GO:0048864"(stem cell development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050857"(positive regulation of antigen receptor-mediated signaling pathway)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051607"(defense response to virus)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0098857"(membrane microdomain)|go:"GO:1903615"(positive regulation of protein tyrosine phosphatase activity)|go:"GO:1903979"(negative regulation of microglial cell activation)|go:"GO:1904155"(DN2 thymocyte differentiation)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000473"(positive regulation of hematopoietic stem cell migration)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016335(Leukocyte common antigen)|interpro:IPR024739|interpro:IPR029021|interpro:IPR036116|mint:P08575|rcsb pdb:1YGR|rcsb pdb:1YGU|rcsb pdb:5FMV|rcsb pdb:5FN6|rcsb pdb:5FN7|reactome:R-HSA-202427|reactome:R-HSA-416700|reactome:R-HSA-6798695|mint:MINT-1349949(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2018/04/06 rogid:rrMiH60EcAzRWaaapYTjNU5+1IY9606 rogid:rrMiH60EcAzRWaaapYTjNU5+1IY9606 intact-crc:BC0A9D7860B893BF|rigid:/aCe9f+TS2SV6uFYvuaLkOU7+7U false tag:?-?(MINT-1349963)|binding-associated region:579-599(MINT-1349960) binding-associated region:579-599(MINT-1349950)|tag:?-?(MINT-1349953) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28827 uniprotkb:P28827 intact:EBI-2257317|uniprotkb:D3DUH8|uniprotkb:A7MBN1|uniprotkb:J3QL11|ensembl:ENSP00000331418 intact:EBI-2257317|uniprotkb:D3DUH8|uniprotkb:A7MBN1|uniprotkb:J3QL11|ensembl:ENSP00000331418 psi-mi:ptprm_human(display_long)|uniprotkb:PTPRM(gene name)|psi-mi:PTPRM(display_short)|uniprotkb:PTPRL1(gene name synonym) psi-mi:ptprm_human(display_long)|uniprotkb:PTPRM(gene name)|psi-mi:PTPRM(display_short)|uniprotkb:PTPRL1(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669564|mint:MINT-62284|imex:IM-10850-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-668N|refseq:NP_001098714.1|refseq:NP_002836.3|ensembl:ENSG00000173482(gene)|ensembl:ENST00000332175(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010842"(retina layer formation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|rcsb pdb:1RPM|rcsb pdb:2C9A|rcsb pdb:2V5Y|mint:MINT-1349702(identity) dip:DIP-668N|refseq:NP_001098714.1|refseq:NP_002836.3|ensembl:ENSG00000173482(gene)|ensembl:ENST00000332175(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010842"(retina layer formation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0031175"(neuron projection development)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|rcsb pdb:1RPM|rcsb pdb:2C9A|rcsb pdb:2V5Y|mint:MINT-1349692(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2014/10/16 rogid:RDqdhoXIs3y1t81EMhi9W98ObCg9606 rogid:RDqdhoXIs3y1t81EMhi9W98ObCg9606 intact-crc:9D1A917493FF0702|rigid:4rwO5U7wUAlb16yNYEpKVMxNQiw false binding-associated region:743-764(MINT-1349703)|tag:?-?(MINT-1349706) binding-associated region:743-764(MINT-1349693)|tag:?-?(MINT-1349696) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15262 uniprotkb:Q15262 intact:EBI-474052|uniprotkb:Q14763|uniprotkb:Q5TG10|uniprotkb:Q5TG11|uniprotkb:B2RTQ8|uniprotkb:B7ZMG0|ensembl:ENSP00000357198|ensembl:ENSP00000486442 intact:EBI-474052|uniprotkb:Q14763|uniprotkb:Q5TG10|uniprotkb:Q5TG11|uniprotkb:B2RTQ8|uniprotkb:B7ZMG0|ensembl:ENSP00000357198|ensembl:ENSP00000486442 psi-mi:ptprk_human(display_long)|uniprotkb:PTPRK(gene name)|psi-mi:PTPRK(display_short)|uniprotkb:PTPK(gene name synonym) psi-mi:ptprk_human(display_long)|uniprotkb:PTPRK(gene name)|psi-mi:PTPRK(display_short)|uniprotkb:PTPK(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669610|mint:MINT-62285|imex:IM-10850-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129120.1|refseq:NP_002835.2|refseq:NP_001278910.1|refseq:NP_001278913.1|ensembl:ENSG00000152894(gene)|ensembl:ENSG00000273993(gene)|ensembl:ENST00000368215(transcript)|ensembl:ENST00000628183(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031256"(leading edge membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048041"(focal adhesion assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|rcsb pdb:2C7S|reactome:R-HSA-182971|interpro:IPR000998(MAM)|mint:MINT-1350135(identity) refseq:NP_001129120.1|refseq:NP_002835.2|refseq:NP_001278910.1|refseq:NP_001278913.1|ensembl:ENSG00000152894(gene)|ensembl:ENSG00000273993(gene)|ensembl:ENST00000368215(transcript)|ensembl:ENST00000628183(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031256"(leading edge membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048041"(focal adhesion assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|rcsb pdb:2C7S|reactome:R-HSA-182971|interpro:IPR000998(MAM)|mint:MINT-1350145(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:40yQxlMyaqsPBoKB+vm75uweT9Y9606 rogid:40yQxlMyaqsPBoKB+vm75uweT9Y9606 intact-crc:28B83FA6FDC7CEDD|rigid:CQQuYWT3Ugp+dz5hE07xkgqHcps false tag:?-?(MINT-1350139)|binding-associated region:753-774(MINT-1350136) binding-associated region:753-774(MINT-1350146)|tag:?-?(MINT-1350149) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O14522 uniprotkb:O14522 intact:EBI-728180|uniprotkb:O43655|uniprotkb:O75664|uniprotkb:Q5W0X9|uniprotkb:Q5W0Y1|uniprotkb:Q9BR24|uniprotkb:Q9BR28|uniprotkb:Q9H0Y8|uniprotkb:Q9NTL1|uniprotkb:Q9NU72|uniprotkb:Q9UBD2|uniprotkb:Q9UJL7|ensembl:ENSP00000362283|uniprotkb:A8E4R6 intact:EBI-728180|uniprotkb:O43655|uniprotkb:O75664|uniprotkb:Q5W0X9|uniprotkb:Q5W0Y1|uniprotkb:Q9BR24|uniprotkb:Q9BR28|uniprotkb:Q9H0Y8|uniprotkb:Q9NTL1|uniprotkb:Q9NU72|uniprotkb:Q9UBD2|uniprotkb:Q9UJL7|ensembl:ENSP00000362283|uniprotkb:A8E4R6 psi-mi:ptprt_human(display_long)|uniprotkb:PTPRT(gene name)|psi-mi:PTPRT(display_short)|uniprotkb:KIAA0283(gene name synonym)|uniprotkb:Receptor-type tyrosine-protein phosphatase rho(gene name synonym) psi-mi:ptprt_human(display_long)|uniprotkb:PTPRT(gene name)|psi-mi:PTPRT(display_short)|uniprotkb:KIAA0283(gene name synonym)|uniprotkb:Receptor-type tyrosine-protein phosphatase rho(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669639|mint:MINT-62286|imex:IM-10850-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196090(gene)|ensembl:ENST00000373187(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|mint:O14522|rcsb pdb:2OOQ|refseq:NP_008981.4|refseq:NP_573400.3|dip:DIP-33967N|mint:MINT-1350313(identity) ensembl:ENSG00000196090(gene)|ensembl:ENST00000373187(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1904893"(negative regulation of receptor signaling pathway via STAT)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|interpro:IPR041201|mint:O14522|rcsb pdb:2OOQ|refseq:NP_008981.4|refseq:NP_573400.3|dip:DIP-33967N|mint:MINT-1350323(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2014/10/16 rogid:GKfTiUL+lsxQPu7/ibKdpoUy6rE9606 rogid:GKfTiUL+lsxQPu7/ibKdpoUy6rE9606 intact-crc:B4DC9934C6A3C070|rigid:pzaj8ddlLQzpmpeN8mO8orTwdRs false binding-associated region:753-772(MINT-1350314)|tag:?-?(MINT-1350317) tag:?-?(MINT-1350327)|binding-associated region:753-772(MINT-1350324) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92729 uniprotkb:Q92729 intact:EBI-7052301|ensembl:ENSP00000334941|uniprotkb:Q59HA4|intact:MINT-1349420|uniprotkb:Q5SYU5|uniprotkb:O00197|uniprotkb:A6H8L1|uniprotkb:P78399|uniprotkb:Q92735|uniprotkb:Q5SYU4|uniprotkb:Q92850 intact:EBI-7052301|ensembl:ENSP00000334941|uniprotkb:Q59HA4|intact:MINT-1349420|uniprotkb:Q5SYU5|uniprotkb:O00197|uniprotkb:A6H8L1|uniprotkb:P78399|uniprotkb:Q92735|uniprotkb:Q5SYU4|uniprotkb:Q92850 psi-mi:ptpru_human(display_long)|uniprotkb:PTPRU(gene name)|psi-mi:PTPRU(display_short)|uniprotkb:PCP2(gene name synonym)|uniprotkb:FMI(gene name synonym)|uniprotkb:PTPRO(gene name synonym)|uniprotkb:Receptor-type protein-tyrosine phosphatase psi(gene name synonym)|uniprotkb:Pancreatic carcinoma phosphatase 2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor omicron(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase J(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pi(gene name synonym) psi-mi:ptpru_human(display_long)|uniprotkb:PTPRU(gene name)|psi-mi:PTPRU(display_short)|uniprotkb:PCP2(gene name synonym)|uniprotkb:FMI(gene name synonym)|uniprotkb:PTPRO(gene name synonym)|uniprotkb:Receptor-type protein-tyrosine phosphatase psi(gene name synonym)|uniprotkb:Pancreatic carcinoma phosphatase 2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor omicron(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase J(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase pi(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669668|mint:MINT-62287|imex:IM-10850-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000060656(gene)|ensembl:ENST00000345512(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:Q92729|rcsb pdb:6SUB|rcsb pdb:6SUC|reactome:R-HSA-1433557|refseq:NP_001181930.1|refseq:NP_005695.3|refseq:NP_573439.2|refseq:NP_573438.3|mint:MINT-1349474(identity) ensembl:ENSG00000060656(gene)|ensembl:ENST00000345512(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000998(MAM)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:Q92729|rcsb pdb:6SUB|rcsb pdb:6SUC|reactome:R-HSA-1433557|refseq:NP_001181930.1|refseq:NP_005695.3|refseq:NP_573439.2|refseq:NP_573438.3|mint:MINT-1349464(identity) - comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin|comment:"Stoichiometry: 1.0" comment:mint|function:Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Forms complexes with beta-catenin and gamma-catenin/plakoglobin|comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2014/10/16 rogid:zEYsgwn37ANdzpiq5f8h2TL+XD89606 rogid:zEYsgwn37ANdzpiq5f8h2TL+XD89606 intact-crc:95508E62666ACC85|rigid:pRBYfoCph+d9nxOcv/sigasQiis false tag:?-?(MINT-1349478)|binding-associated region:747-770(MINT-1349475) tag:?-?(MINT-1349468)|binding-associated region:747-770(MINT-1349465) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13332 uniprotkb:Q13332 intact:EBI-711536|ensembl:ENSP00000467537|uniprotkb:Q2M3R7|uniprotkb:O75255|uniprotkb:O75870|uniprotkb:Q15718|uniprotkb:Q16341|intact:EBI-1058503 intact:EBI-711536|ensembl:ENSP00000467537|uniprotkb:Q2M3R7|uniprotkb:O75255|uniprotkb:O75870|uniprotkb:Q15718|uniprotkb:Q16341|intact:EBI-1058503 psi-mi:ptprs_human(display_long)|uniprotkb:PTPRS(gene name)|psi-mi:PTPRS(display_short)|uniprotkb:Receptor-type tyrosine-protein phosphatase sigma(gene name synonym) psi-mi:ptprs_human(display_long)|uniprotkb:PTPRS(gene name)|psi-mi:PTPRS(display_short)|uniprotkb:Receptor-type tyrosine-protein phosphatase sigma(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669743|mint:MINT-62289|imex:IM-10850-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008201"(heparin binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021510"(spinal cord development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099560"(synaptic membrane adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2FH7|rcsb pdb:2YD2|rcsb pdb:2YD3|rcsb pdb:2YD9|rcsb pdb:4BPC|rcsb pdb:4PBX|reactome:R-HSA-3000178|reactome:R-HSA-388844|reactome:R-HSA-8849932|reactome:R-HSA-9034015|ensembl:ENSG00000105426(gene)|ensembl:ENST00000587303(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|refseq:NP_002841.3|refseq:NP_570923.2|refseq:NP_570924.2|refseq:NP_570925.2|refseq:XP_005259663.1|refseq:XP_005259666.1|refseq:XP_016882554.1|refseq:XP_016882555.1|refseq:XP_016882556.1|mint:MINT-1349654(identity) go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008201"(heparin binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021510"(spinal cord development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099560"(synaptic membrane adhesion)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:2FH7|rcsb pdb:2YD2|rcsb pdb:2YD3|rcsb pdb:2YD9|rcsb pdb:4BPC|rcsb pdb:4PBX|reactome:R-HSA-3000178|reactome:R-HSA-388844|reactome:R-HSA-8849932|reactome:R-HSA-9034015|ensembl:ENSG00000105426(gene)|ensembl:ENST00000587303(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|refseq:NP_002841.3|refseq:NP_570923.2|refseq:NP_570924.2|refseq:NP_570925.2|refseq:XP_005259663.1|refseq:XP_005259666.1|refseq:XP_016882554.1|refseq:XP_016882555.1|refseq:XP_016882556.1|mint:MINT-1349644(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:mD7s7/H78PNJDAPLckZ19jmdAn89606 rogid:mD7s7/H78PNJDAPLckZ19jmdAn89606 intact-crc:927E371F56D3613E|rigid:U0tb41gY6o2Fm2C5akpRrduYwwE false tag:?-?(MINT-1349658)|binding-associated region:1283-1305(MINT-1349655) binding-associated region:1283-1305(MINT-1349645)|tag:?-?(MINT-1349648) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10586 uniprotkb:P10586 intact:EBI-7188069|ensembl:ENSP00000353030|uniprotkb:Q5T022|uniprotkb:Q5W9G2|intact:MINT-1189049|uniprotkb:D3DPX7|uniprotkb:Q5T021|uniprotkb:D3DPX6|uniprotkb:Q86WS0 intact:EBI-7188069|ensembl:ENSP00000353030|uniprotkb:Q5T022|uniprotkb:Q5W9G2|intact:MINT-1189049|uniprotkb:D3DPX7|uniprotkb:Q5T021|uniprotkb:D3DPX6|uniprotkb:Q86WS0 psi-mi:ptprf_human(display_long)|uniprotkb:PTPRF(gene name)|psi-mi:PTPRF(display_short)|uniprotkb:LAR(gene name synonym)|uniprotkb:Leukocyte common antigen related(gene name synonym) psi-mi:ptprf_human(display_long)|uniprotkb:PTPRF(gene name)|psi-mi:PTPRF(display_short)|uniprotkb:LAR(gene name synonym)|uniprotkb:Leukocyte common antigen related(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669714|mint:MINT-62288|imex:IM-10850-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000142949(gene)|ensembl:ENST00000359947(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0016477"(cell migration)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0035373"(chondroitin sulfate proteoglycan binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900121"(negative regulation of receptor binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:P10586|rcsb pdb:1LAR|rcsb pdb:2DJU|rcsb pdb:2DN7|rcsb pdb:2EDX|rcsb pdb:2EDY|rcsb pdb:2YD5|rcsb pdb:2YD8|rcsb pdb:4N5U|rcsb pdb:6KR4|rcsb pdb:6TPT|rcsb pdb:6TPU|rcsb pdb:6TPV|rcsb pdb:6TPW|reactome:R-HSA-388844|reactome:R-HSA-8849932|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|refseq:NP_002831.2|refseq:NP_569707.2|mint:MINT-1349382(identity) ensembl:ENSG00000142949(gene)|ensembl:ENST00000359947(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0016477"(cell migration)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0035373"(chondroitin sulfate proteoglycan binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900121"(negative regulation of receptor binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:P10586|rcsb pdb:1LAR|rcsb pdb:2DJU|rcsb pdb:2DN7|rcsb pdb:2EDX|rcsb pdb:2EDY|rcsb pdb:2YD5|rcsb pdb:2YD8|rcsb pdb:4N5U|rcsb pdb:6KR4|rcsb pdb:6TPT|rcsb pdb:6TPU|rcsb pdb:6TPV|rcsb pdb:6TPW|reactome:R-HSA-388844|reactome:R-HSA-8849932|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|refseq:NP_002831.2|refseq:NP_569707.2|mint:MINT-1349372(identity) - comment:mint|comment:homomint|comment:"Stoichiometry: 1.0" comment:mint|comment:homomint|comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:JLPH3tIxOkyVmJ0mZsBZ+TanLVk9606 rogid:JLPH3tIxOkyVmJ0mZsBZ+TanLVk9606 intact-crc:4777FA29A4E09CA0|rigid:a3VVg04cqI/p28es8WOJBWD48ZA false binding-associated region:1260-1283(MINT-1349383)|tag:?-?(MINT-1349386) binding-associated region:1260-1283(MINT-1349373)|tag:?-?(MINT-1349376) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18433 uniprotkb:P18433 intact:EBI-2609645|uniprotkb:D3DVX5|uniprotkb:Q14513|uniprotkb:Q7Z2I2|uniprotkb:A8K2G8|uniprotkb:Q96TD9|ensembl:ENSP00000382787|intact:EBI-11028029 intact:EBI-2609645|uniprotkb:D3DVX5|uniprotkb:Q14513|uniprotkb:Q7Z2I2|uniprotkb:A8K2G8|uniprotkb:Q96TD9|ensembl:ENSP00000382787|intact:EBI-11028029 psi-mi:ptpra_human(display_long)|uniprotkb:PTPRA(gene name)|psi-mi:PTPRA(display_short)|uniprotkb:PTPA(gene name synonym)|uniprotkb:PTPRL2(gene name synonym) psi-mi:ptpra_human(display_long)|uniprotkb:PTPRA(gene name)|psi-mi:PTPRA(display_short)|uniprotkb:PTPA(gene name synonym)|uniprotkb:PTPRL2(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669818|mint:MINT-62291|imex:IM-10850-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132670(gene)|ensembl:ENST00000399903(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|mint:P18433|rcsb pdb:6UZT|reactome:R-HSA-375165|reactome:R-HSA-5673001|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|refseq:NP_002827.1|refseq:NP_543030.1|refseq:NP_543031.1|mint:MINT-1349396(identity) ensembl:ENSG00000132670(gene)|ensembl:ENST00000399903(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099699"(integral component of synaptic membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR027262|interpro:IPR029021|mint:P18433|rcsb pdb:6UZT|reactome:R-HSA-375165|reactome:R-HSA-5673001|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|refseq:NP_002827.1|refseq:NP_543030.1|refseq:NP_543031.1|mint:MINT-1349406(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2018/04/06 rogid:dWjvj2zG0Kapb8MhDjinV+LpG109606 rogid:dWjvj2zG0Kapb8MhDjinV+LpG109606 intact-crc:A043319D6F986F23|rigid:1h3EmYZNwAQ4GRlYhNCtUeESksI false binding-associated region:152-175(MINT-1349397)|tag:?-?(MINT-1349400) binding-associated region:152-175(MINT-1349407)|tag:?-?(MINT-1349410) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23468 uniprotkb:P23468 intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439 intact:EBI-2682990|uniprotkb:B1ALA0|intact:EBI-11575870|uniprotkb:Q3KPJ0|uniprotkb:Q3KPJ1|uniprotkb:Q3KPJ2|uniprotkb:F5GWT7|ensembl:ENSP00000348812|ensembl:ENSP00000370593|ensembl:ENSP00000438164|ensembl:ENSP00000489063|ensembl:ENSP00000489257|ensembl:ENSP00000489439 psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short) psi-mi:ptprd_human(display_long)|uniprotkb:PTPRD(gene name)|psi-mi:PTPRD(display_short) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669772|mint:MINT-62290|imex:IM-10850-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932|mint:MINT-1350207(identity) refseq:XP_011516294.1|refseq:NP_002830.1|refseq:NP_001164496.1|refseq:NP_569075.2|refseq:NP_569076.2|refseq:XP_006716895.1|refseq:XP_006716896.1|refseq:XP_006716898.1|refseq:XP_016870480.1|dip:DIP-17023N|ensembl:ENSG00000153707(gene)|ensembl:ENSG00000282932(gene)|ensembl:ENST00000356435(transcript)|ensembl:ENST00000381196(transcript)|ensembl:ENST00000540109(transcript)|ensembl:ENST00000634556(transcript)|ensembl:ENST00000634608(transcript)|ensembl:ENST00000635012(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0050776"(regulation of immune response)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099545"(trans-synaptic signaling by trans-synaptic complex)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|rcsb pdb:1X5Z|rcsb pdb:2DLH|rcsb pdb:2YD6|rcsb pdb:2YD7|rcsb pdb:4RCA|rcsb pdb:5WY8|rcsb pdb:5XNP|rcsb pdb:6X3A|reactome:R-HSA-388844|reactome:R-HSA-8849932|mint:MINT-1350197(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606 rogid:h0umOPLFZFiTKY4k0hqwRCeemug9606 intact-crc:CE4E8E327D7415AF|rigid:AAcT8jIhINFbHOVxiWV8EaCSQoI false binding-associated region:1267-1290(MINT-1350208)|tag:?-?(MINT-1350211) binding-associated region:1267-1290(MINT-1350198)|tag:?-?(MINT-1350201) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23469 uniprotkb:P23469 intact:EBI-2258070|uniprotkb:Q13345|uniprotkb:Q96KQ6|uniprotkb:Q5VWH3|uniprotkb:Q5VWH4|ensembl:ENSP00000254667 intact:EBI-2258070|uniprotkb:Q13345|uniprotkb:Q96KQ6|uniprotkb:Q5VWH3|uniprotkb:Q5VWH4|ensembl:ENSP00000254667 psi-mi:ptpre_human(display_long)|uniprotkb:PTPRE(gene name)|psi-mi:PTPRE(display_short) psi-mi:ptpre_human(display_long)|uniprotkb:PTPRE(gene name)|psi-mi:PTPRE(display_short) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669847|mint:MINT-62292|imex:IM-10850-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303605.1|refseq:NP_001303606.1|refseq:XP_016871957.1|refseq:NP_006495.1|refseq:XP_005252748.1|refseq:NP_001310283.1|refseq:NP_569119.1|ensembl:ENSG00000132334(gene)|ensembl:ENST00000254667(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR029021|rcsb pdb:2JJD|rcsb pdb:6D3F|rcsb pdb:6D4D|rcsb pdb:6D4F|mint:MINT-1349842(identity) refseq:NP_001303605.1|refseq:NP_001303606.1|refseq:XP_016871957.1|refseq:NP_006495.1|refseq:XP_005252748.1|refseq:NP_001310283.1|refseq:NP_569119.1|ensembl:ENSG00000132334(gene)|ensembl:ENST00000254667(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR029021|rcsb pdb:2JJD|rcsb pdb:6D3F|rcsb pdb:6D4D|rcsb pdb:6D4F|mint:MINT-1349832(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:dNMLfHqBmbW25nCn5i+ZPPuNrOQ9606 rogid:dNMLfHqBmbW25nCn5i+ZPPuNrOQ9606 intact-crc:9AF7CAB397D95FCE|rigid:ZllhcFvzw095ldK1+N15eyNx3Mk false tag:?-?(MINT-1349846)|binding-associated region:47-69(MINT-1349843) binding-associated region:47-69(MINT-1349833)|tag:?-?(MINT-1349836) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23470 uniprotkb:P23470 intact:EBI-2258115|uniprotkb:Q15623|uniprotkb:Q59EE0|uniprotkb:Q68DU5|uniprotkb:B2RU12|uniprotkb:B7ZLX5|ensembl:ENSP00000418112 intact:EBI-2258115|uniprotkb:Q15623|uniprotkb:Q59EE0|uniprotkb:Q68DU5|uniprotkb:B2RU12|uniprotkb:B7ZLX5|ensembl:ENSP00000418112 psi-mi:ptprg_human(display_long)|uniprotkb:PTPRG(gene name)|psi-mi:PTPRG(display_short)|uniprotkb:PTPG(gene name synonym) psi-mi:ptprg_human(display_long)|uniprotkb:PTPRG(gene name)|psi-mi:PTPRG(display_short)|uniprotkb:PTPG(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669893|mint:MINT-62293|imex:IM-10850-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002832.3|refseq:XP_005265410.1|ensembl:ENSG00000144724(gene)|ensembl:ENST00000474889(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:2H4V|rcsb pdb:2HY3|rcsb pdb:2NLK|rcsb pdb:2PBN|rcsb pdb:3JXH|rcsb pdb:3QCB|rcsb pdb:3QCC|rcsb pdb:3QCD|rcsb pdb:3QCE|rcsb pdb:3QCF|rcsb pdb:3QCG|rcsb pdb:3QCH|rcsb pdb:3QCI|rcsb pdb:3QCJ|rcsb pdb:3QCK|rcsb pdb:3QCL|rcsb pdb:3QCM|rcsb pdb:3QCN|rcsb pdb:5E5R|go:"GO:0007420"(brain development)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:MINT-1350023(identity) refseq:NP_002832.3|refseq:XP_005265410.1|ensembl:ENSG00000144724(gene)|ensembl:ENST00000474889(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:2H4V|rcsb pdb:2HY3|rcsb pdb:2NLK|rcsb pdb:2PBN|rcsb pdb:3JXH|rcsb pdb:3QCB|rcsb pdb:3QCC|rcsb pdb:3QCD|rcsb pdb:3QCE|rcsb pdb:3QCF|rcsb pdb:3QCG|rcsb pdb:3QCH|rcsb pdb:3QCI|rcsb pdb:3QCJ|rcsb pdb:3QCK|rcsb pdb:3QCL|rcsb pdb:3QCM|rcsb pdb:3QCN|rcsb pdb:5E5R|go:"GO:0007420"(brain development)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:MINT-1350013(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2014/10/16 rogid:9184ikfJS88Ndx9dhhblgdCFI+Y9606 rogid:9184ikfJS88Ndx9dhhblgdCFI+Y9606 intact-crc:7F8F290568B8C51A|rigid:pnpQvRV8KPdRwsp7IhBs9VFoieY false binding-associated region:738-760(MINT-1350024)|tag:?-?(MINT-1350027) tag:?-?(MINT-1350017)|binding-associated region:738-760(MINT-1350014) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23471 uniprotkb:P23471 intact:EBI-2263175|uniprotkb:A4D0W5|uniprotkb:O76043|uniprotkb:Q9UDR6|uniprotkb:C9JFM0|ensembl:ENSP00000377047 intact:EBI-2263175|uniprotkb:A4D0W5|uniprotkb:O76043|uniprotkb:Q9UDR6|uniprotkb:C9JFM0|ensembl:ENSP00000377047 psi-mi:ptprz_human(display_long)|uniprotkb:PTPRZ1(gene name)|psi-mi:PTPRZ1(display_short)|uniprotkb:HTPZP2(gene name synonym)|uniprotkb:PTPRZ(gene name synonym)|uniprotkb:PTPRZ2(gene name synonym)|uniprotkb:PTPZ(gene name synonym)|uniprotkb:R-PTP-zeta-2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 2(gene name synonym) psi-mi:ptprz_human(display_long)|uniprotkb:PTPRZ1(gene name)|psi-mi:PTPRZ1(display_short)|uniprotkb:HTPZP2(gene name synonym)|uniprotkb:PTPRZ(gene name synonym)|uniprotkb:PTPRZ2(gene name synonym)|uniprotkb:PTPZ(gene name synonym)|uniprotkb:R-PTP-zeta-2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type Z polypeptide 2(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669930|mint:MINT-62294|imex:IM-10850-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005250576.1|refseq:NP_001193767.1|refseq:NP_001193768.1|refseq:NP_002842.2|dip:DIP-42063N|ensembl:ENSG00000106278(gene)|ensembl:ENST00000393386(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:3JXF|rcsb pdb:3S97|rcsb pdb:5AWX|rcsb pdb:5H08|reactome:R-HSA-449836|mint:MINT-1350379(identity) refseq:XP_005250576.1|refseq:NP_001193767.1|refseq:NP_001193768.1|refseq:NP_002842.2|dip:DIP-42063N|ensembl:ENSG00000106278(gene)|ensembl:ENST00000393386(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007417"(central nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072534"(perineuronal net)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036398|interpro:IPR041887|rcsb pdb:3JXF|rcsb pdb:3S97|rcsb pdb:5AWX|rcsb pdb:5H08|reactome:R-HSA-449836|mint:MINT-1350369(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:iOG4w3mPNa50dCrP0V4V5r1TaSM9606 rogid:iOG4w3mPNa50dCrP0V4V5r1TaSM9606 intact-crc:7901D14A14E5B9B4|rigid:n7z8/8wCCHLtFyEizJOr6rw3F3s false tag:?-?(MINT-1350383)|binding-associated region:1637-1659(MINT-1350380) tag:?-?(MINT-1350373)|binding-associated region:1637-1659(MINT-1350370) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P23467 uniprotkb:P23467 intact:EBI-1265766|uniprotkb:B7ZKT0|uniprotkb:C9JX87|uniprotkb:Q14D85|uniprotkb:Q3MIV7|uniprotkb:B7ZKS8|uniprotkb:F5H3G6|ensembl:ENSP00000261266 intact:EBI-1265766|uniprotkb:B7ZKT0|uniprotkb:C9JX87|uniprotkb:Q14D85|uniprotkb:Q3MIV7|uniprotkb:B7ZKS8|uniprotkb:F5H3G6|ensembl:ENSP00000261266 psi-mi:ptprb_human(display_long)|uniprotkb:PTPRB(gene name)|psi-mi:PTPRB(display_short)|uniprotkb:PTPB(gene name synonym)|uniprotkb:Vascular endothelial protein tyrosine phosphatase(gene name synonym) psi-mi:ptprb_human(display_long)|uniprotkb:PTPRB(gene name)|psi-mi:PTPRB(display_short)|uniprotkb:PTPB(gene name synonym)|uniprotkb:Vascular endothelial protein tyrosine phosphatase(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7669986|mint:MINT-62295|imex:IM-10850-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001103224.1|refseq:NP_001193900.1|refseq:NP_001193901.1|refseq:NP_002828.3|refseq:NP_001317133.1|ensembl:ENSG00000127329(gene)|ensembl:ENST00000261266(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:P23467|rcsb pdb:2AHS|rcsb pdb:2H02|rcsb pdb:2H03|rcsb pdb:2H04|rcsb pdb:2HC1|rcsb pdb:2HC2|rcsb pdb:2I3R|rcsb pdb:2I3U|rcsb pdb:2I4E|rcsb pdb:2I4G|rcsb pdb:2I4H|rcsb pdb:2I5X|reactome:R-HSA-6798695|mint:MINT-1349796(identity) refseq:NP_001103224.1|refseq:NP_001193900.1|refseq:NP_001193901.1|refseq:NP_002828.3|refseq:NP_001317133.1|ensembl:ENSG00000127329(gene)|ensembl:ENST00000261266(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:P23467|rcsb pdb:2AHS|rcsb pdb:2H02|rcsb pdb:2H03|rcsb pdb:2H04|rcsb pdb:2HC1|rcsb pdb:2HC2|rcsb pdb:2I3R|rcsb pdb:2I3U|rcsb pdb:2I4E|rcsb pdb:2I4G|rcsb pdb:2I4H|rcsb pdb:2I5X|reactome:R-HSA-6798695|mint:MINT-1349786(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:X+GhwOoXfwd3PaFx3UFdQNkNAL89606 rogid:X+GhwOoXfwd3PaFx3UFdQNkNAL89606 intact-crc:3CDE2A0F72227154|rigid:NmZ97IhRxOZrIzuSoKQVcedo1ss false tag:?-?(MINT-1349800)|binding-associated region:1622-1641(MINT-1349797) binding-associated region:1622-1641(MINT-1349787)|tag:?-?(MINT-1349790) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q12913 uniprotkb:Q12913 intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010 intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010 psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym) psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7670088|mint:MINT-62296|imex:IM-10850-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369|mint:MINT-1349973(identity) refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369|mint:MINT-1349991(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1 F2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2014/10/16 rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606 rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606 intact-crc:4F847D57659F2948|rigid:pxih3Ueb1I7Vu7JGcT8TivM+jL8 false mutation increasing interaction:991-991(MINT-1349979)|mutation increasing interaction:992-992(MINT-1349977)|tag:?-?(MINT-1349985)|mutation decreasing interaction:983-983(MINT-1349981)|binding-associated region:972-996(MINT-1349974)|mutation decreasing interaction:979-979|mutation decreasing interaction:975-975 mutation increasing interaction:992-992(MINT-1349997)|mutation increasing interaction:991-991(MINT-1349995)|mutation decreasing interaction:975-975(MINT-1349999)|tag:?-?(MINT-1350003)|binding-associated region:972-996(MINT-1349992)|mutation decreasing interaction:983-983|mutation decreasing interaction:979-979 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9HD43 uniprotkb:Q9HD43 intact:EBI-1267176|uniprotkb:Q15426|uniprotkb:Q2NKN9|uniprotkb:Q2NKP0|intact:EBI-2826558|uniprotkb:C9JCH2|ensembl:ENSP00000365528 intact:EBI-1267176|uniprotkb:Q15426|uniprotkb:Q2NKN9|uniprotkb:Q2NKP0|intact:EBI-2826558|uniprotkb:C9JCH2|ensembl:ENSP00000365528 psi-mi:ptprh_human(display_long)|uniprotkb:PTPRH(gene name)|psi-mi:PTPRH(display_short)|uniprotkb:SAP1(gene name synonym)|uniprotkb:Transmembrane-type protein-tyrosine phosphatase type H(gene name synonym)|uniprotkb:Stomach cancer-associated protein tyrosine phosphatase 1(gene name synonym) psi-mi:ptprh_human(display_long)|uniprotkb:PTPRH(gene name)|psi-mi:PTPRH(display_short)|uniprotkb:SAP1(gene name synonym)|uniprotkb:Transmembrane-type protein-tyrosine phosphatase type H(gene name synonym)|uniprotkb:Stomach cancer-associated protein tyrosine phosphatase 1(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7670189|mint:MINT-62297|imex:IM-10850-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154912.2|refseq:NP_002833.4|ensembl:ENSG00000080031(gene)|ensembl:ENST00000376350(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR028855|interpro:IPR029021|interpro:IPR036116|mint:Q9HD43|mint:MINT-1349574(identity) refseq:NP_001154912.2|refseq:NP_002833.4|ensembl:ENSG00000080031(gene)|ensembl:ENST00000376350(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR028855|interpro:IPR029021|interpro:IPR036116|mint:Q9HD43|mint:MINT-1349564(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2018/04/06 rogid:a7NZuEFgvJhp4nMMr3+0yi9KT8Y9606 rogid:a7NZuEFgvJhp4nMMr3+0yi9KT8Y9606 intact-crc:EF343B2E4839F999|rigid:OHgmBB2KG9GAp/Mp+7+BcCEfHdI false tag:?-?(MINT-1349578)|binding-associated region:754-776(MINT-1349575) tag:?-?(MINT-1349568)|binding-associated region:754-776(MINT-1349565) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16827 uniprotkb:Q16827 intact:EBI-723739|uniprotkb:A0AV39|uniprotkb:Q13101|ensembl:ENSP00000281171|ensembl:ENSP00000501352|ensembl:ENSP00000501538|uniprotkb:Q9UBF0|uniprotkb:Q9UBT5|uniprotkb:Q8IYG3 intact:EBI-723739|uniprotkb:A0AV39|uniprotkb:Q13101|ensembl:ENSP00000281171|ensembl:ENSP00000501352|ensembl:ENSP00000501538|uniprotkb:Q9UBF0|uniprotkb:Q9UBT5|uniprotkb:Q8IYG3 psi-mi:ptpro_human(display_long)|uniprotkb:Glomerular epithelial protein 1(gene name synonym)|uniprotkb:Protein tyrosine phosphatase U2(gene name synonym)|uniprotkb:PTPRO(gene name)|psi-mi:PTPRO(display_short)|uniprotkb:GLEPP1(gene name synonym)|uniprotkb:PTPU2(gene name synonym) psi-mi:ptpro_human(display_long)|uniprotkb:Glomerular epithelial protein 1(gene name synonym)|uniprotkb:Protein tyrosine phosphatase U2(gene name synonym)|uniprotkb:PTPRO(gene name)|psi-mi:PTPRO(display_short)|uniprotkb:GLEPP1(gene name synonym)|uniprotkb:PTPU2(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7670237|mint:MINT-62298|imex:IM-10850-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002839.1|refseq:NP_109592.1|ensembl:ENST00000674316(transcript)|ensembl:ENST00000674261(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003093"(regulation of glomerular filtration)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032835"(glomerulus development)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036060"(slit diaphragm assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR042996|rcsb pdb:2G59|rcsb pdb:2GJT|reactome:R-HSA-9034015|go:"GO:0030424"(axon)|ensembl:ENSG00000151490(gene)|ensembl:ENST00000281171(transcript)|refseq:NP_109593.1|refseq:NP_109594.1|refseq:NP_109595.1|refseq:NP_109596.1|mint:MINT-1349506(identity) refseq:NP_002839.1|refseq:NP_109592.1|ensembl:ENST00000674316(transcript)|ensembl:ENST00000674261(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003093"(regulation of glomerular filtration)|go:"GO:0003105"(negative regulation of glomerular filtration)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007411"(axon guidance)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017147"(Wnt-protein binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030426"(growth cone)|go:"GO:0032835"(glomerulus development)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0036060"(slit diaphragm assembly)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR042996|rcsb pdb:2G59|rcsb pdb:2GJT|reactome:R-HSA-9034015|go:"GO:0030424"(axon)|ensembl:ENSG00000151490(gene)|ensembl:ENST00000281171(transcript)|refseq:NP_109593.1|refseq:NP_109594.1|refseq:NP_109595.1|refseq:NP_109596.1|mint:MINT-1349516(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2014/10/16 rogid:On01UwkglziGIJIEHE8TrOkOHd89606 rogid:On01UwkglziGIJIEHE8TrOkOHd89606 intact-crc:2D6F755B056B081D|rigid:rowHzEqOIc9LgTCKVHgZG6uVxK8 false tag:?-?(MINT-1349510)|binding-associated region:820-844(MINT-1349507) tag:?-?(MINT-1349520)|binding-associated region:820-844(MINT-1349517) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q16849 uniprotkb:Q16849 intact:EBI-728153|uniprotkb:Q08319|uniprotkb:Q53QD6|uniprotkb:Q6NSL1|uniprotkb:B4DK12|uniprotkb:F5GZS3|ensembl:ENSP00000295718 intact:EBI-728153|uniprotkb:Q08319|uniprotkb:Q53QD6|uniprotkb:Q6NSL1|uniprotkb:B4DK12|uniprotkb:F5GZS3|ensembl:ENSP00000295718 psi-mi:ptprn_human(display_long)|uniprotkb:PTPRN(gene name)|psi-mi:PTPRN(display_short)|uniprotkb:ICA3(gene name synonym)|uniprotkb:ICA512(gene name synonym)|uniprotkb:PTP IA-2(gene name synonym)|uniprotkb:Islet cell antigen 512(gene name synonym)|uniprotkb:Islet cell autoantigen 3(gene name synonym) psi-mi:ptprn_human(display_long)|uniprotkb:PTPRN(gene name)|psi-mi:PTPRN(display_short)|uniprotkb:ICA3(gene name synonym)|uniprotkb:ICA512(gene name synonym)|uniprotkb:PTP IA-2(gene name synonym)|uniprotkb:Islet cell antigen 512(gene name synonym)|uniprotkb:Islet cell autoantigen 3(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7670382|mint:MINT-62300|imex:IM-10850-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002837.1|refseq:NP_001186692.1|refseq:NP_001186693.1|ensembl:ENSG00000054356(gene)|ensembl:ENST00000295718(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001553"(luteinization)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043627"(response to estrogen)|go:"GO:0043679"(axon terminus)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051020"(GTPase binding)|go:"GO:0051591"(response to cAMP)|go:"GO:1904692"(positive regulation of type B pancreatic cell proliferation)|go:"GO:1990502"(dense core granule maturation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR021613|interpro:IPR029021|interpro:IPR029403|interpro:IPR033522|interpro:IPR038112|mint:Q16849|rcsb pdb:2I1Y|rcsb pdb:2QT7|rcsb pdb:3N01|rcsb pdb:3N4W|rcsb pdb:3NG8|rcsb pdb:3NP5|mint:MINT-1350237(identity) refseq:NP_002837.1|refseq:NP_001186692.1|refseq:NP_001186693.1|ensembl:ENSG00000054356(gene)|ensembl:ENST00000295718(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001553"(luteinization)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032868"(response to insulin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043627"(response to estrogen)|go:"GO:0043679"(axon terminus)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051020"(GTPase binding)|go:"GO:0051591"(response to cAMP)|go:"GO:1904692"(positive regulation of type B pancreatic cell proliferation)|go:"GO:1990502"(dense core granule maturation)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR021613|interpro:IPR029021|interpro:IPR029403|interpro:IPR033522|interpro:IPR038112|mint:Q16849|rcsb pdb:2I1Y|rcsb pdb:2QT7|rcsb pdb:3N01|rcsb pdb:3N4W|rcsb pdb:3NG8|rcsb pdb:3NP5|mint:MINT-1350247(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:tcloEPzsWu3GJ03BlPeLfgZgAjA9606 rogid:tcloEPzsWu3GJ03BlPeLfgZgAjA9606 intact-crc:216122A805C7CBA5|rigid:rENY0YLs9hWVRgtoOlXCTn8gCTM false tag:?-?(MINT-1350241)|binding-associated region:577-598(MINT-1350238) tag:?-?(MINT-1350251)|binding-associated region:577-598(MINT-1350248) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q15256 uniprotkb:Q15256 intact:EBI-2265659|uniprotkb:B7Z3J1|uniprotkb:F5GXR7|uniprotkb:B2R5Z7|uniprotkb:O00342|uniprotkb:Q92682|uniprotkb:Q9UE65|ensembl:ENSP00000283228 intact:EBI-2265659|uniprotkb:B7Z3J1|uniprotkb:F5GXR7|uniprotkb:B2R5Z7|uniprotkb:O00342|uniprotkb:Q92682|uniprotkb:Q9UE65|ensembl:ENSP00000283228 psi-mi:ptprr_human(display_long)|uniprotkb:PTPRR(gene name)|psi-mi:PTPRR(display_short)|uniprotkb:ECPTP(gene name synonym)|uniprotkb:PTPRQ(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PCPTP1(gene name synonym)|uniprotkb:NC-PTPCOM1(gene name synonym)|uniprotkb:Ch-1PTPase(gene name synonym) psi-mi:ptprr_human(display_long)|uniprotkb:PTPRR(gene name)|psi-mi:PTPRR(display_short)|uniprotkb:ECPTP(gene name synonym)|uniprotkb:PTPRQ(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase PCPTP1(gene name synonym)|uniprotkb:NC-PTPCOM1(gene name synonym)|uniprotkb:Ch-1PTPase(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7670318|mint:MINT-62299|imex:IM-10850-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001193945.1|refseq:NP_002840.2|refseq:NP_570897.2|refseq:NP_001193944.1|dip:DIP-42066N|ensembl:ENSG00000153233(gene)|ensembl:ENST00000283228(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008356(Protein-tyrosine phosphatase, KIM-containing)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016334(Protein-tyrosine phosphatase, receptor type R/non-receptor type 5)|interpro:IPR029021|mint:Q15256|rcsb pdb:2A8B|mint:MINT-1350092(identity) refseq:NP_001193945.1|refseq:NP_002840.2|refseq:NP_570897.2|refseq:NP_001193944.1|dip:DIP-42066N|ensembl:ENSG00000153233(gene)|ensembl:ENST00000283228(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR008356(Protein-tyrosine phosphatase, KIM-containing)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016334(Protein-tyrosine phosphatase, receptor type R/non-receptor type 5)|interpro:IPR029021|mint:Q15256|rcsb pdb:2A8B|mint:MINT-1350102(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:8so8NViDHoE+HVOlmv8aq0GJC/w9606 rogid:8so8NViDHoE+HVOlmv8aq0GJC/w9606 intact-crc:951272CDC18906FF|rigid:9qfOps5p7zOv6r/DsB/oLBbpLr8 false tag:?-?(MINT-1350096)|binding-associated region:228-248(MINT-1350093) tag:?-?(MINT-1350106)|binding-associated region:228-248(MINT-1350103) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92932 uniprotkb:Q92932 intact:EBI-310576|uniprotkb:Q8N4I5|uniprotkb:Q92662|intact:EBI-947109|uniprotkb:Q9Y4F8|uniprotkb:E9PC57|uniprotkb:Q9Y4I6|ensembl:ENSP00000374069 intact:EBI-310576|uniprotkb:Q8N4I5|uniprotkb:Q92662|intact:EBI-947109|uniprotkb:Q9Y4F8|uniprotkb:E9PC57|uniprotkb:Q9Y4I6|ensembl:ENSP00000374069 psi-mi:ptpr2_human(display_long)|uniprotkb:PTPRN2(gene name)|psi-mi:PTPRN2(display_short)|uniprotkb:KIAA0387(gene name synonym)|uniprotkb:Islet cell autoantigen-related protein(gene name synonym)|uniprotkb:Phogrin(gene name synonym) psi-mi:ptpr2_human(display_long)|uniprotkb:PTPRN2(gene name)|psi-mi:PTPRN2(display_short)|uniprotkb:KIAA0387(gene name synonym)|uniprotkb:Islet cell autoantigen-related protein(gene name synonym)|uniprotkb:Phogrin(gene name synonym) psi-mi:"MI:0370"(tox-r dimerization assay) Chin et al. (2005) pubmed:15978577|imex:IM-10850|mint:MINT-5217789 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7670445|mint:MINT-62301|imex:IM-10850-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002838.2|refseq:NP_570857.2|refseq:NP_570858.2|refseq:NP_001295196.1|refseq:NP_001295197.1|ensembl:ENSG00000155093(gene)|ensembl:ENST00000389418(transcript)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043195"(terminal bouton)|go:"GO:0043235"(receptor complex)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR021613|interpro:IPR029021|interpro:IPR029403|interpro:IPR033522|interpro:IPR038112|rcsb pdb:2QEP|rcsb pdb:4HTI|rcsb pdb:4HTJ|reactome:R-HSA-6798695|mint:MINT-1349756(identity) refseq:NP_002838.2|refseq:NP_570857.2|refseq:NP_570858.2|refseq:NP_001295196.1|refseq:NP_001295197.1|ensembl:ENSG00000155093(gene)|ensembl:ENST00000389418(transcript)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043195"(terminal bouton)|go:"GO:0043235"(receptor complex)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR021613|interpro:IPR029021|interpro:IPR029403|interpro:IPR033522|interpro:IPR038112|rcsb pdb:2QEP|rcsb pdb:4HTI|rcsb pdb:4HTJ|reactome:R-HSA-6798695|mint:MINT-1349746(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:T1 F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2005/08/23 2016/10/21 rogid:afvWmPT2RuvhMQ0X8iCHpp/ouF09606 rogid:afvWmPT2RuvhMQ0X8iCHpp/ouF09606 intact-crc:5C5A5F207CEDF3A1|rigid:urHXWQQseiew5F4O3C29So/piWE false binding-associated region:615-636(MINT-1349757)|tag:?-?(MINT-1349760) binding-associated region:615-636(MINT-1349747)|tag:?-?(MINT-1349750) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)