#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13639 uniprotkb:Q13639 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:"MI:0012"(bioluminescence resonance energy transfer) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7632806|mint:MINT-60079|imex:IM-10816-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347484(identity) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347478(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/07/05 2014/10/16 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 intact-crc:CD03BDB6F9230837|rigid:xfygD7VS3j+INn7YETlKWUKIKSc false tag:?-?(MINT-1347485) tag:?-?(MINT-1347479) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13639 uniprotkb:Q13639 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:"MI:0012"(bioluminescence resonance energy transfer) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7632853|mint:MINT-60080|imex:IM-10816-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347496(identity) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347502(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2005/07/05 2014/10/16 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 intact-crc:6E7FF9279A758472|rigid:xfygD7VS3j+INn7YETlKWUKIKSc false tag:?-?(MINT-1347497) tag:?-?(MINT-1347503) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13639 uniprotkb:P07550 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 intact:EBI-491169|uniprotkb:Q9UH95|uniprotkb:Q9UHA1|uniprotkb:O14823|uniprotkb:O14824|uniprotkb:O14825|uniprotkb:O14826|uniprotkb:Q4JG18|uniprotkb:Q8NEQ9|uniprotkb:Q9UMZ5|uniprotkb:Q6P4D8|uniprotkb:B0LPE4|uniprotkb:B2R7X2|uniprotkb:Q53GA6|uniprotkb:Q6GMT4|uniprotkb:Q96EC3|uniprotkb:Q9UCZ0|uniprotkb:Q9UCZ1|uniprotkb:Q9UCZ2|uniprotkb:Q9UCZ3|ensembl:ENSP00000305372 psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:adrb2_human(display_long)|uniprotkb:Beta-2 adrenoreceptor(gene name synonym)|uniprotkb:ADRB2(gene name)|psi-mi:ADRB2(display_short)|uniprotkb:ADRB2R(gene name synonym)|uniprotkb:B2AR(gene name synonym) psi-mi:"MI:0012"(bioluminescence resonance energy transfer) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7632899|mint:MINT-60083|imex:IM-10816-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347548(identity) refseq:NP_000015.1|ensembl:ENSG00000169252(gene)|ensembl:ENST00000305988(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002025"(norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004941"(beta2-adrenergic receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007171"(activation of transmembrane receptor protein tyrosine kinase activity)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009409"(response to cold)|go:"GO:0010008"(endosome membrane)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031649"(heat generation)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0061885"(positive regulation of mini excitatory postsynaptic potential)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0051380"(norepinephrine binding)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000332(Adrenergic receptor, beta 2)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P07550|rcsb pdb:1GQ4|rcsb pdb:2R4R|rcsb pdb:2R4S|rcsb pdb:2RH1|rcsb pdb:3D4S|rcsb pdb:3KJ6|rcsb pdb:3NY8|rcsb pdb:3NY9|rcsb pdb:3NYA|rcsb pdb:3P0G|rcsb pdb:3PDS|rcsb pdb:3SN6|rcsb pdb:4GBR|rcsb pdb:4LDE|rcsb pdb:4LDL|rcsb pdb:4LDO|rcsb pdb:4QKX|rcsb pdb:5D5A|rcsb pdb:5D5B|rcsb pdb:5D6L|rcsb pdb:5JQH|rcsb pdb:5X7D|rcsb pdb:6E67|rcsb pdb:6KR8|rcsb pdb:6MXT|rcsb pdb:6N48|rcsb pdb:6NI3|rcsb pdb:6OBA|rcsb pdb:6PRZ|rcsb pdb:6PS0|rcsb pdb:6PS1|rcsb pdb:6PS2|rcsb pdb:6PS3|rcsb pdb:6PS4|rcsb pdb:6PS5|rcsb pdb:6PS6|rcsb pdb:7BZ2|rcsb pdb:7DHI|rcsb pdb:7DHR|reactome:R-HSA-390696|reactome:R-HSA-418555|reactome:R-HSA-5689880|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9660821|dip:DIP-33948N|mint:MINT-1347554(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2005/07/05 2014/10/16 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 rogid:+pZmEUm9SKroeqpa7uI44Bz18zo9606 intact-crc:6A6EAFEAE112FE96|rigid:9kJ8YggQmnaVLiY9guf9T2ggivc false tag:?-?(MINT-1347549) tag:?-?(MINT-1347555) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13639-7 uniprotkb:Q13639 intact:EBI-7632879|intact:MINT-1347474 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 psi-mi:q13639-7(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:"MI:0012"(bioluminescence resonance energy transfer) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-7632872|mint:MINT-60082|imex:IM-10816-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6656425(isoform-parent)|mint:MINT-1347570(identity) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347564(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2005/07/05 2014/10/16 rogid:UMhZiApCJyhrLslKW27JesFMdqE9606 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 intact-crc:551AC092149FDE1F|rigid:tbRVx9A5haIedlQFTECa5VxbSQQ false tag:?-?(MINT-1347571) tag:?-?(MINT-1347565) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13639 uniprotkb:Q13639 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7632987|mint:MINT-60078|imex:IM-10816-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347514(identity) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347520(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/07/05 2014/10/16 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 intact-crc:00A733CC276DB45B|rigid:xfygD7VS3j+INn7YETlKWUKIKSc false tag:?-?(MINT-1347515) tag:?-?(MINT-1347521) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13639 uniprotkb:Q13639 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 intact:EBI-6656425|ensembl:ENSP00000367120|ensembl:ENSP00000485747|uniprotkb:Q546Q1|uniprotkb:Q684M0|uniprotkb:Q712M9|uniprotkb:Q96KH9|uniprotkb:Q96KI0|uniprotkb:Q9H199|uniprotkb:Q9NY73|uniprotkb:Q9UBM6|uniprotkb:Q9UBT4|uniprotkb:Q9UE22|uniprotkb:Q9UE23|uniprotkb:Q9UQR6|uniprotkb:C4WYH4 psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:5ht4r_human(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7633016|mint:MINT-60077|imex:IM-10816-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347538(identity) refseq:NP_001273339.1|ensembl:ENSG00000164270(gene)|ensembl:ENST00000377888(transcript)|ensembl:ENST00000631296(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0007198"(adenylate cyclase-inhibiting serotonin receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032098"(regulation of appetite)|go:"GO:0045202"(synapse)|go:"GO:0051378"(serotonin binding)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001520(5-Hydroxytryptamine 4 receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q13639|rcsb pdb:5EM9|reactome:R-HSA-390666|reactome:R-HSA-418555|reactome:R-HSA-9660821|refseq:NP_000861.1|refseq:NP_001035259.1|refseq:NP_001035262.2|refseq:NP_001035263.1|refseq:NP_955525.1|mint:MINT-1347532(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2005/07/05 2014/10/16 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 rogid:5+1AMJ2Bq46D7PZcb+0pVHgBY/U9606 intact-crc:8DAF14339066880F|rigid:xfygD7VS3j+INn7YETlKWUKIKSc false tag:?-?(MINT-1347539) tag:?-?(MINT-1347533) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q13639-7 uniprotkb:Q13639-7 intact:EBI-7632879|intact:MINT-1347474 intact:EBI-7632879|intact:MINT-1347474 psi-mi:q13639-7(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:q13639-7(display_long)|uniprotkb:HTR4(gene name)|psi-mi:HTR4(display_short)|uniprotkb:Serotonin receptor 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Berthouze et al. (2005) pubmed:15896782|imex:IM-10816|mint:MINT-5217738 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7633035|mint:MINT-60081|imex:IM-10816-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-6656425(isoform-parent)|mint:MINT-1347580(identity) intact:EBI-6656425(isoform-parent)|mint:MINT-1347586(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line) - 2005/07/05 2014/10/16 rogid:UMhZiApCJyhrLslKW27JesFMdqE9606 rogid:UMhZiApCJyhrLslKW27JesFMdqE9606 intact-crc:9EAC377DB1565D4A|rigid:F5/WKR/o42UR6fw8vypSbjr4Ue8 false tag:?-?(MINT-1347581) tag:?-?(MINT-1347587) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)