#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O35601 uniprotkb:Q62418 intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947 intact:EBI-1550322|uniprotkb:Q80WP1|uniprotkb:Q8BH56|uniprotkb:Q3TG34|uniprotkb:Q3U5X3|uniprotkb:Q3U8I5|uniprotkb:Q3UZ33|uniprotkb:Q5NCI5|uniprotkb:Q5NCI6|uniprotkb:Q5NCI7|ensembl:ENSMUSP00000020769 psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym) psi-mi:dbnl_mouse(display_long)|uniprotkb:Dbnl(gene name)|psi-mi:Dbnl(display_short)|uniprotkb:Abp1(gene name synonym)|uniprotkb:Sh3p7(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Actin-binding protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yuan et al. (2005) pubmed:15848169|imex:IM-11481|mint:MINT-5217684 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7599521|mint:MINT-58560|imex:IM-11481-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-1345951(identity) refseq:NP_001139780.1|refseq:NP_001139781.1|refseq:NP_038838.1|dip:DIP-39835N|ensembl:ENSMUSG00000020476(gene)|ensembl:ENSMUST00000020769(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|interpro:IPR035717|interpro:IPR036028|mint:Q62418|reactome:R-MMU-264870|reactome:R-MMU-6794361|reactome:R-MMU-6798695|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|mint:MINT-1345959(identity) - comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2005/06/07 2014/10/16 rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090 rogid:uRFrfUfKF7cfhsrbleRauR33+g810090 intact-crc:AEF1E3AD6874999F|rigid:eHvJiLpheZx6RNUw3U8l8ZBP5IE false tag:?-?(MINT-1345954)|binding-associated region:1-339(MINT-1345952) tag:?-?(MINT-1345962)|binding-associated region:149-433(MINT-1345960) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35601 uniprotkb:Q62418 intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947 intact:EBI-1550322|uniprotkb:Q80WP1|uniprotkb:Q8BH56|uniprotkb:Q3TG34|uniprotkb:Q3U5X3|uniprotkb:Q3U8I5|uniprotkb:Q3UZ33|uniprotkb:Q5NCI5|uniprotkb:Q5NCI6|uniprotkb:Q5NCI7|ensembl:ENSMUSP00000020769 psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym) psi-mi:dbnl_mouse(display_long)|uniprotkb:Dbnl(gene name)|psi-mi:Dbnl(display_short)|uniprotkb:Abp1(gene name synonym)|uniprotkb:Sh3p7(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Actin-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Yuan et al. (2005) pubmed:15848169|imex:IM-11481|mint:MINT-5217684 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7599558|mint:MINT-58561|imex:IM-11481-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-1346002(identity) refseq:NP_001139780.1|refseq:NP_001139781.1|refseq:NP_038838.1|dip:DIP-39835N|ensembl:ENSMUSG00000020476(gene)|ensembl:ENSMUST00000020769(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|interpro:IPR035717|interpro:IPR036028|mint:Q62418|reactome:R-MMU-264870|reactome:R-MMU-6794361|reactome:R-MMU-6798695|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|mint:MINT-1345996(identity) - comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:"1) Fyb is His tagged

2) Abp1 is GST tagged"|figure legend:F4E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/07 2014/10/16 rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090 rogid:uRFrfUfKF7cfhsrbleRauR33+g810090 intact-crc:DE7AE9695938B817|rigid:eHvJiLpheZx6RNUw3U8l8ZBP5IE false tag:?-?(MINT-1346006)|binding-associated region:1-339(MINT-1346003) tag:?-?(MINT-1345997) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35601 uniprotkb:Q62418 intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947 intact:EBI-1550322|uniprotkb:Q80WP1|uniprotkb:Q8BH56|uniprotkb:Q3TG34|uniprotkb:Q3U5X3|uniprotkb:Q3U8I5|uniprotkb:Q3UZ33|uniprotkb:Q5NCI5|uniprotkb:Q5NCI6|uniprotkb:Q5NCI7|ensembl:ENSMUSP00000020769 psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym) psi-mi:dbnl_mouse(display_long)|uniprotkb:Dbnl(gene name)|psi-mi:Dbnl(display_short)|uniprotkb:Abp1(gene name synonym)|uniprotkb:Sh3p7(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Actin-binding protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Yuan et al. (2005) pubmed:15848169|imex:IM-11481|mint:MINT-5217684 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7599583|mint:MINT-58562|imex:IM-11481-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-1345982(identity) refseq:NP_001139780.1|refseq:NP_001139781.1|refseq:NP_038838.1|dip:DIP-39835N|ensembl:ENSMUSG00000020476(gene)|ensembl:ENSMUST00000020769(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|interpro:IPR035717|interpro:IPR036028|mint:Q62418|reactome:R-MMU-264870|reactome:R-MMU-6794361|reactome:R-MMU-6798695|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|mint:MINT-1345973(identity) - comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4F|comment:"1) Fyb is His tagged"|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/06/07 2014/10/16 rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090 rogid:uRFrfUfKF7cfhsrbleRauR33+g810090 intact-crc:C6C87A99EAA4978F|rigid:eHvJiLpheZx6RNUw3U8l8ZBP5IE false binding-associated region:1-339(MINT-1345983)|tag:?-?(MINT-1345986) binding-associated region:371-433(MINT-1345974)|tag:?-?(MINT-1345977) - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35601 uniprotkb:Q62418 intact:EBI-7353747|uniprotkb:Q9Z2H3|intact:MINT-244320|ensembl:ENSMUSP00000087947 intact:EBI-1550322|uniprotkb:Q80WP1|uniprotkb:Q8BH56|uniprotkb:Q3TG34|uniprotkb:Q3U5X3|uniprotkb:Q3U8I5|uniprotkb:Q3UZ33|uniprotkb:Q5NCI5|uniprotkb:Q5NCI6|uniprotkb:Q5NCI7|ensembl:ENSMUSP00000020769 psi-mi:fyb1_mouse(display_long)|uniprotkb:Fyb1(gene name)|psi-mi:Fyb1(display_short)|uniprotkb:Adhesion and degranulation promoting adaptor protein(gene name synonym)|uniprotkb:FYB-120/130(gene name synonym)|uniprotkb:FYN-T-binding protein(gene name synonym)|uniprotkb:Fyb(gene name synonym)|uniprotkb:SLAP-130(gene name synonym)|uniprotkb:SLP-76-associated phosphoprotein(gene name synonym) psi-mi:dbnl_mouse(display_long)|uniprotkb:Dbnl(gene name)|psi-mi:Dbnl(display_short)|uniprotkb:Abp1(gene name synonym)|uniprotkb:Sh3p7(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Actin-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yuan et al. (2005) pubmed:15848169|imex:IM-11481|mint:MINT-5217684 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7599641|mint:MINT-58563|imex:IM-11481-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035945.1|refseq:NP_001265198.1|ensembl:ENSMUSG00000022148(gene)|ensembl:ENSMUST00000090461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008289"(lipid binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR029294|interpro:IPR030635|interpro:IPR035540|interpro:IPR036028|interpro:IPR043443|reactome:R-MMU-202433|reactome:R-MMU-391160|dip:DIP-41350N|mint:MINT-1346022(identity) refseq:NP_001139780.1|refseq:NP_001139781.1|refseq:NP_038838.1|dip:DIP-39835N|ensembl:ENSMUSG00000020476(gene)|ensembl:ENSMUST00000020769(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|interpro:IPR035717|interpro:IPR036028|mint:Q62418|reactome:R-MMU-264870|reactome:R-MMU-6794361|reactome:R-MMU-6798695|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|mint:MINT-1346018(identity) - comment:mint|function:"Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F5C|comment:SHORT LABEL=J774 cells|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-4(in vivo)|taxid:-4(in vivo) - 2005/06/07 2014/10/16 rogid:6rfpz9eZT3M5F0khbMoHGg+/vEU10090 rogid:uRFrfUfKF7cfhsrbleRauR33+g810090 intact-crc:4841F80B4B3FFBB5|rigid:eHvJiLpheZx6RNUw3U8l8ZBP5IE false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)