#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96B97-1	uniprotkb:P08393	intact:EBI-7585212|intact:MINT-233719|ensembl:ENSP00000380921	intact:EBI-6148881	psi-mi:q96b97-1(display_long)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CD2-binding protein 3(gene name synonym)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)	psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liang et al. (2005)	pubmed:15824310|mint:MINT-5217660	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585206|mint:MINT-60939	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-346595(isoform-parent)|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|mint:MINT-1345105(identity)	refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX|mint:MINT-1345111(identity)	-	isoform-comment:Interacts with CBL.|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/12	2014/10/16	rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606	rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299	intact-crc:59BBEFC25A4F726F|rigid:+f3mU6XzR7Q4/GNNq+B4BUMNCtY	false	tag:?-?(MINT-1345106)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q96B97	uniprotkb:P08393	intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921	intact:EBI-6148881	psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym)	psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liang et al. (2005)	pubmed:15824310|mint:MINT-5217660	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585334|mint:MINT-60941	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization)|mint:MINT-1345149(identity)	refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX|mint:MINT-1345158(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/12	2014/10/16	rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606	rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299	intact-crc:4299C53849EF05B1|rigid:+f3mU6XzR7Q4/GNNq+B4BUMNCtY	false	tag:?-?(MINT-1345153)|binding-associated region:101-155(MINT-1345150)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q96B97	uniprotkb:P08393	intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921	intact:EBI-6148881	psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym)	psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liang et al. (2005)	pubmed:15824310|mint:MINT-5217660	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585296|mint:MINT-60940	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization)|mint:MINT-1345165(identity)	refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX|mint:MINT-1345174(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/12	2014/10/16	rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606	rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299	intact-crc:6877E35F1AB839F9|rigid:+f3mU6XzR7Q4/GNNq+B4BUMNCtY	false	tag:?-?(MINT-1345169)|binding-associated region:2-56(MINT-1345166)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q96B97-1	uniprotkb:P08393	intact:EBI-7585212|intact:MINT-233719|ensembl:ENSP00000380921	intact:EBI-6148881	psi-mi:q96b97-1(display_long)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CD2-binding protein 3(gene name synonym)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)	psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liang et al. (2005)	pubmed:15824310|mint:MINT-5217660	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585374|mint:MINT-60943	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-346595(isoform-parent)|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|mint:MINT-1345090(identity)	refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX|mint:MINT-1345094(identity)	-	isoform-comment:Interacts with CBL.|comment:mint|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/12	2014/10/16	rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606	rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299	intact-crc:C085BB7809CBF2BA|rigid:+f3mU6XzR7Q4/GNNq+B4BUMNCtY	false	-	binding-associated region:245-395(MINT-1345095)|tag:?-?(MINT-1345097)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q96B97	uniprotkb:P08393	intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921	intact:EBI-6148881	psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym)	psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liang et al. (2005)	pubmed:15824310|mint:MINT-5217660	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585354|mint:MINT-60942	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization)|mint:MINT-1345133(identity)	refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX|mint:MINT-1345142(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/12	2014/10/16	rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606	rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299	intact-crc:AED0B330B67EB025|rigid:+f3mU6XzR7Q4/GNNq+B4BUMNCtY	false	tag:?-?(MINT-1345137)|binding-associated region:270-326(MINT-1345134)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P22681	uniprotkb:P08393	intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033	intact:EBI-6148881	psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)	psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym)	psi-mi:"MI:0096"(pull down)	Liang et al. (2005)	pubmed:15824310|mint:MINT-5217660	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585393|mint:MINT-60944	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005179.2|ensembl:ENSP00000264033|dip:DIP-189N|ensembl:ENSG00000110395(gene)|ensembl:ENST00000264033(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6O03|rcsb pdb:6XAR|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9706369|reactome:R-HSA-9706377|mint:MINT-1345118(identity)	refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX|mint:MINT-1345122(identity)	-	comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F3|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/07/12	2014/10/16	rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606	rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299	intact-crc:7AD8884F28111CC2|rigid:HBUrShMoXOb0YVTvi4DDsxnhA2o	false	-	tag:?-?(MINT-1345125)|binding-associated region:245-510(MINT-1345123)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0072"(monoclonal antibody western blot)