#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8FLC5	uniprotkb:P07623	intact:EBI-7557686|intact:MINT-1343547|ensemblbacteria:AAN78520	intact:EBI-1134411|uniprotkb:Q2M6U1|ensemblbacteria:AAC76983|ensemblbacteria:BAE78015	psi-mi:dnaj_ecol6(display_long)|uniprotkb:dnaJ(gene name)|psi-mi:dnaJ(display_short)|uniprotkb:c0020(locus name)	psi-mi:metas_ecoli(display_long)|uniprotkb:metAS(gene name)|psi-mi:metAS(display_short)|uniprotkb:Homoserine transsuccinylase(gene name synonym)|uniprotkb:metA(gene name synonym)|uniprotkb:JW3973(locus name)|uniprotkb:b4013(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gur et al. (2005)	pubmed:15792799|imex:IM-10960|mint:MINT-5217616	taxid:199310(ecol6)|taxid:199310("Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7557680|mint:MINT-58278|imex:IM-10960-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR012724(Chaperone DnaJ)|refseq:WP_001118464.1|mint:Q8FLC5|interpro:IPR036869|interpro:IPR036410|interpro:IPR018253|interpro:IPR008971(HSP40/DnaJ peptide-binding)|ensemblbacteria:AAN78520(transcript)|ensemblbacteria:c0020(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051082"(unfolded protein binding)|mint:MINT-1343562(identity)	refseq:WP_001122779.1|refseq:NP_418437.1|interpro:IPR005697(Homoserine O-succinyltransferase)|ensemblbacteria:AAC76983(transcript)|ensemblbacteria:b4013(gene)|ensemblbacteria:BAE78015(gene)|ensemblbacteria:BAE78015(transcript)|go:"GO:0004414"(homoserine O-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008899"(homoserine O-succinyltransferase activity)|go:"GO:0019281"(L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine)|rcsb pdb:6MTG|rcsb pdb:7CBE|interpro:IPR029062|interpro:IPR033752|mint:P07623|mint:MINT-1343558(identity)	-	comment:mint|function:Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon interaction with the dnaJ-bound protein, dnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from dnaK; ATP binding to dnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between dnaJ, dnaK and grpE are required for fully efficient folding. Also involved, together with dnaK and grpE, in the DNA replication of plasmids through activation of initiation proteins|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F6|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/04/26	2014/10/16	rogid:JydkPixHDPbuHXSsztfP3YX5XJA199310	rogid:2TwrvsMTbn3w5aE/iZKTh0Mi5yg83333	intact-crc:4C7F2E8E2243A2D6|rigid:+FsbXKRFO56y6X55+aRPgUZ8BnA	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)