#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O88307	uniprotkb:Q6P5E6	intact:EBI-7540114|uniprotkb:Q3UHM3|uniprotkb:O54711|uniprotkb:O70581|intact:MINT-1342356|ensembl:ENSMUSP00000058613	intact:EBI-2616239|uniprotkb:Q3U374|uniprotkb:Q6PFX3|uniprotkb:Q6ZPY8|uniprotkb:Q8BM76|uniprotkb:Q9DC15|ensembl:ENSMUSP00000033160|ensembl:ENSMUSP00000115581	psi-mi:sorl_mouse(display_long)|uniprotkb:Sorl1(gene name)|psi-mi:Sorl1(display_short)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:Gp250(gene name synonym)	psi-mi:gga2_mouse(display_long)|uniprotkb:Gga2(gene name)|psi-mi:Gga2(display_short)|uniprotkb:Kiaa1080(gene name synonym)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2005)	pubmed:15774496|mint:MINT-5217598	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7540109|mint:MINT-58554	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035566.2|ensembl:ENSMUSG00000049313(gene)|ensembl:ENSMUST00000060989(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|go:"GO:0006898"(receptor-mediated endocytosis)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|interpro:IPR006581(VPS10)|dip:DIP-42439N|mint:MINT-1342385(identity)	refseq:NP_083034.1|ensembl:ENSMUSG00000030872(gene)|ensembl:ENSMUST00000033160(transcript)|ensembl:ENSMUST00000124566(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q6P5E6|mint:MINT-1342376(identity)	-	comment:mint|function:"Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F8B|comment:homomint|comment:mint	taxid:10090(mouse-nih 3t3-l1)|taxid:10090(Mus musculus)	-	2005/06/06	2014/10/16	rogid:Q9DlzVMLmbQrNjfd9Pr/1B5FeTw10090	rogid:aG5tjatIjLUkQFBS1VG6nk8OFxI10090	intact-crc:451D72C0E92DE86B|rigid:iqxKjTKeL5dgGcapPkUq25ElBMs	false	tag:?-?(MINT-1342386)	binding-associated region:68-101(MINT-1342377)|tag:?-?(MINT-1342380)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14142	uniprotkb:Q6P5E6	intact:EBI-7540210|uniprotkb:Q3TPK6|uniprotkb:Q9JJN9|intact:MINT-1342290|ensembl:ENSMUSP00000018710	intact:EBI-2616239|uniprotkb:Q3U374|uniprotkb:Q6PFX3|uniprotkb:Q6ZPY8|uniprotkb:Q8BM76|uniprotkb:Q9DC15|ensembl:ENSMUSP00000033160|ensembl:ENSMUSP00000115581	psi-mi:glut4_mouse(display_long)|uniprotkb:Slc2a4(gene name)|psi-mi:Slc2a4(display_short)|uniprotkb:Glut4(gene name synonym)|uniprotkb:Glucose transporter type 4, insulin-responsive(gene name synonym)|uniprotkb:GT2(gene name synonym)	psi-mi:gga2_mouse(display_long)|uniprotkb:Gga2(gene name)|psi-mi:Gga2(display_short)|uniprotkb:Kiaa1080(gene name synonym)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Li et al. (2005)	pubmed:15774496|mint:MINT-5217598	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7540254|mint:MINT-58555	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033230.2|ensembl:ENSMUSG00000018566(gene)|ensembl:ENSMUST00000018710(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005360"("insulin-responsive glucose:proton symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010021"(amylopectin biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031550"(positive regulation of brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046323"(glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098694"(regulation of synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0098793"(presynapse)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002441("Glucose transporter, type 4 (GLUT4)")|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P14142|reactome:R-MMU-189200|interpro:IPR003663(Sugar transporter)|dip:DIP-42440N|mint:MINT-1342346(identity)	refseq:NP_083034.1|ensembl:ENSMUSG00000030872(gene)|ensembl:ENSMUST00000033160(transcript)|ensembl:ENSMUST00000124566(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q6P5E6|mint:MINT-1342337(identity)	-	comment:mint|function:Insulin-regulated facilitative glucose transporter|function:"Defects in Slc2a4 may be the cause of certain post-receptor defects in non-insulin-dependent diabetes mellitus (NIDDM)"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F8B|comment:The authors suggest that sortilin mediates binding of GGA to Glut4.|comment:homomint|comment:mint	taxid:10090(mouse-nih 3t3-l1)|taxid:10090(Mus musculus)	-	2005/06/06	2014/10/16	rogid:xH3TdOXTafR/dDOuhIjpvctUufM10090	rogid:aG5tjatIjLUkQFBS1VG6nk8OFxI10090	intact-crc:92744AA63B21F53E|rigid:M8afwLBHpsWxBkJKJSvbDlaMcO8	false	tag:?-?(MINT-1342347)	tag:?-?(MINT-1342341)|binding-associated region:68-101(MINT-1342338)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P14142	uniprotkb:Q6P5E6	intact:EBI-7540210|uniprotkb:Q3TPK6|uniprotkb:Q9JJN9|intact:MINT-1342290|ensembl:ENSMUSP00000018710	intact:EBI-2616239|uniprotkb:Q3U374|uniprotkb:Q6PFX3|uniprotkb:Q6ZPY8|uniprotkb:Q8BM76|uniprotkb:Q9DC15|ensembl:ENSMUSP00000033160|ensembl:ENSMUSP00000115581	psi-mi:glut4_mouse(display_long)|uniprotkb:Slc2a4(gene name)|psi-mi:Slc2a4(display_short)|uniprotkb:Glut4(gene name synonym)|uniprotkb:Glucose transporter type 4, insulin-responsive(gene name synonym)|uniprotkb:GT2(gene name synonym)	psi-mi:gga2_mouse(display_long)|uniprotkb:Gga2(gene name)|psi-mi:Gga2(display_short)|uniprotkb:Kiaa1080(gene name synonym)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Li et al. (2005)	pubmed:15774496|mint:MINT-5217598	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7540334|mint:MINT-58474	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033230.2|ensembl:ENSMUSG00000018566(gene)|ensembl:ENSMUST00000018710(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005360"("insulin-responsive glucose:proton symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0007611"(learning or memory)|go:"GO:0007614"(short-term memory)|go:"GO:0007616"(long-term memory)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010021"(amylopectin biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031550"(positive regulation of brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046323"(glucose import)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0098694"(regulation of synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0098793"(presynapse)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002441("Glucose transporter, type 4 (GLUT4)")|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P14142|reactome:R-MMU-189200|interpro:IPR003663(Sugar transporter)|dip:DIP-42440N|mint:MINT-1342325(identity)	refseq:NP_083034.1|ensembl:ENSMUSG00000030872(gene)|ensembl:ENSMUST00000033160(transcript)|ensembl:ENSMUST00000124566(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q6P5E6|mint:MINT-1342318(identity)	go:"GO:0048471"(perinuclear region of cytoplasm)	comment:mint|function:Insulin-regulated facilitative glucose transporter|function:"Defects in Slc2a4 may be the cause of certain post-receptor defects in non-insulin-dependent diabetes mellitus (NIDDM)"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F2|comment:homomint|comment:mint	taxid:10090(mouse-nih 3t3-l1)|taxid:10090(Mus musculus)	-	2005/06/06	2014/10/16	rogid:xH3TdOXTafR/dDOuhIjpvctUufM10090	rogid:aG5tjatIjLUkQFBS1VG6nk8OFxI10090	intact-crc:B91FEBA5D98DC826|rigid:M8afwLBHpsWxBkJKJSvbDlaMcO8	false	myc tag:?-?(MINT-1342326)	green fluorescent protein tag:?-?(MINT-1342319)	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0396"(predetermined participant)