#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60831 uniprotkb:O60831 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7524786|mint:MINT-58204|imex:IM-13906-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1339921(identity) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1339927(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4A|comment:JM4 forms up to homotrimers|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/04/05 2014/10/16 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 intact-crc:D5848890A99FC66B|rigid:509SAcSHzzc7QGp3tn+d/DZbgm8 false tag:?-?(MINT-1339922) tag:?-?(MINT-1339928) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60831 uniprotkb:O75915 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258 psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7524822|mint:MINT-58205|imex:IM-13906-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340040(identity) refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|mint:MINT-1340046(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/04/05 2014/10/16 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606 intact-crc:872B55346E4ED3BF|rigid:JkuMRh1Is9Sj1qzXoQlUt/dbj1M false tag:?-?(MINT-1340041) tag:?-?(MINT-1340047) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75915 uniprotkb:P51681 intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258 intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881 psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name) psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7524918|mint:MINT-58208|imex:IM-13906-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|mint:MINT-1339972(identity) go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N|mint:MINT-1339966(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/04/05 2014/10/16 rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606 rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606 intact-crc:C6B2B3EC6ABD41C0|rigid:Zl+517XE3GqWG8daXnD4LGI7tPQ false tag:?-?(MINT-1339973) tag:?-?(MINT-1339967) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60831 uniprotkb:P51681 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881 psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7524880|mint:MINT-58207|imex:IM-13906-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340117(identity) go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N|mint:MINT-1340111(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/04/05 2014/10/16 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606 intact-crc:ACA8FDE7528CF25F|rigid:IZh3tXaJrGzfGFvdHNVqfXoeheI false tag:?-?(MINT-1340118) tag:?-?(MINT-1340112) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O75915 uniprotkb:O60831 intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0428"(imaging technique) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7525001|mint:MINT-58200|imex:IM-13906-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|mint:MINT-1340081(identity) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340074(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/04/05 2014/10/16 rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 intact-crc:EE124C7394CE730A|rigid:JkuMRh1Is9Sj1qzXoQlUt/dbj1M false tag:?-?(MINT-1340082) tag:?-?(MINT-1340075) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O75915 uniprotkb:O60831 intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0428"(imaging technique) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7525072|mint:MINT-58202|imex:IM-13906-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|mint:MINT-1339990(identity) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1339983(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/04/05 2014/10/16 rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 intact-crc:99370A56130E8CE6|rigid:JkuMRh1Is9Sj1qzXoQlUt/dbj1M false tag:?-?(MINT-1339991) tag:?-?(MINT-1339984) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O60831 uniprotkb:P27824 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0428"(imaging technique) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7525036|mint:MINT-58201|imex:IM-13906-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340056(identity) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|mint:MINT-1340063(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/04/05 2014/10/16 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 intact-crc:48C8D0D905B48AD5|rigid:WEyKFYlzaWGr3XniXketOy95iSM false tag:?-?(MINT-1340057) tag:?-?(MINT-1340064) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:O60664 uniprotkb:O60831 intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|intact:EBI-11103673|uniprotkb:K7EQF4|ensembl:ENSP00000221957 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0428"(imaging technique) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7525091|mint:MINT-58203|imex:IM-13906-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019915"(lipid storage)|go:"GO:0030133"(transport vesicle)|ensembl:ENSG00000105355(gene)|go:"GO:0045296"(cadherin binding)|interpro:IPR004279(Perilipin)|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|ensembl:ENST00000221957(transcript)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|mint:MINT-1340099(identity) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340092(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:similar results were obtained in COS cells, data not shown|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2005/04/05 2014/10/16 rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 intact-crc:8DB3BFBD7505133F|rigid:4Ng3SqAndq3xIRMYAQio+diXG5k false tag:?-?(MINT-1340100) tag:?-?(MINT-1340093) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P51681 uniprotkb:O60831 intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7525138|mint:MINT-58199|imex:IM-13906-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N|mint:MINT-1340005(identity) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340011(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2B|comment:BIOSOURCE=dog cf2th cells

The interaction occurs in the membrane fraction of cellular lysates|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9615(canlf-cf2th)|taxid:9615("Canis familiaris (dog) CF2Th thymus cell") - 2005/04/05 2014/10/16 rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 intact-crc:B4A2284BA6DBE57C|rigid:IZh3tXaJrGzfGFvdHNVqfXoeheI false tag:?-?(MINT-1340006) tag:?-?(MINT-1340012) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O60831 uniprotkb:P51681 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 intact:EBI-489374|uniprotkb:O14692|uniprotkb:O14693|uniprotkb:O14695|uniprotkb:O14696|uniprotkb:O14697|uniprotkb:O14698|uniprotkb:O14699|uniprotkb:O14700|uniprotkb:O14701|uniprotkb:O14702|uniprotkb:O14703|uniprotkb:O14704|uniprotkb:O14705|uniprotkb:O14706|uniprotkb:O14707|uniprotkb:O14708|uniprotkb:O15538|uniprotkb:Q9UPA4|ensembl:ENSP00000292303|ensembl:ENSP00000404881 psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:ccr5_human(display_long)|uniprotkb:HIV-1 fusion coreceptor(gene name synonym)|uniprotkb:CHEMR13(gene name synonym)|uniprotkb:CCR5(gene name)|psi-mi:CCR5(display_short)|uniprotkb:CMKBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Schweneker et al. (2005) pubmed:15757671|imex:IM-13906|mint:MINT-5217589 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7525206|mint:MINT-58198|imex:IM-13906-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1|mint:MINT-1340030(identity) go:"GO:0019722"(calcium-mediated signaling)|refseq:NP_000570.1|refseq:NP_001093638.1|ensembl:ENSG00000160791(gene)|ensembl:ENST00000292303(transcript)|ensembl:ENST00000445772(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002407"(dendritic cell chemotaxis)|go:"GO:0003779"(actin binding)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004950"(chemokine receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016493"(C-C chemokine receptor activity)|rcsb pdb:4MBS|rcsb pdb:5UIW|rcsb pdb:5YD3|rcsb pdb:5YD4|rcsb pdb:5YD5|rcsb pdb:5YY4|rcsb pdb:6FGP|rcsb pdb:6MEO|rcsb pdb:6MET|rcsb pdb:7O7F|reactome:R-HSA-173107|reactome:R-HSA-380108|reactome:R-HSA-418594|reactome:R-HSA-6783783|rcsb pdb:2RRS|go:"GO:0023052"(signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0070723"(response to cholesterol)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071791"("chemokine (C-C motif) ligand 5 binding")|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR002240(C-C chemokine receptor, type 5)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P51681|rcsb pdb:1ND8|rcsb pdb:1NE0|rcsb pdb:1OPN|rcsb pdb:1OPT|rcsb pdb:1OPW|rcsb pdb:2L87|go:"GO:0019957"(C-C chemokine binding)|rcsb pdb:2MZX|rcsb pdb:2RLL|dip:DIP-5866N|mint:MINT-1340024(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2005/04/05 2014/10/16 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rogid:qpXGapPDi9co6c1kf2NgfM1qkA89606 intact-crc:62401C0090ABB3C3|rigid:IZh3tXaJrGzfGFvdHNVqfXoeheI false tag:?-?(MINT-1340031) tag:?-?(MINT-1340025) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)